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PROPTOSIS
Forward displacement
of the eyeball beyond
the line joining the
superior and inferior
orbital margin.
EXOPHTHALMOS
It is the same thing. But
it is reserved for Thyroid
eye disease.
 Thyroid eye disease (TED) :
-lid retraction
-lid lag
-proptosis
Endocrine exophthalmos, Malignant
exophthalmos , Dysthroid
ophthalmopathy, Occular Graves’s
disease (OGD), Graves ophthalmopathy
(GO).
 Hyperthyroidism (90%)
 Hypothyroidism (4%)
 Euthyroidism (6%)
 Female (4-6 times)
 Smoking
 Middle age
 Autoimmune thyroid ds.
 HLA-DR3, HLA-B8
 1. American thyroid association (ATA)
 45/F
 Recurrent grave thyrotoxicosis
 Smoker
 TSH 0.03 mu/L , FT4=34 pmol/L
 Red eye, excessive sweating , squint and
double vision.
1. Lid signs
- Dalrymple sign (retraction of upper lids
giving staring and frightened apperance)
- mc and earliest feature
 Von Graefe’s sign ( when eye globe is
moved downward, the upper lid lags
behind)
 Enroth’s sign (fullnes of eye due to
edema)
 Gifford’s sign (difficulty in eversion of
upper lid)
 Stellwag’s sign (infrequent blinking)
 Jellinek’s sign ( increase pigmentation of
the lids)
2. Conjuctival signs
deep injection
chemosis
3. Pupillary signs
ineqquality of dilatation of pupils
1. Congestive
or active
phase
2. Fibrotic or
inactive phase
 Orbital cellulitis
 Idiopathic orbital inflammatory disease
 Sarcoidosis
 Amyloid
 Thyroid function test
 Thyroid autoantibody assay
 Usg
 Ct scan
 MRI
a) Periodic clinical work up
b) Non-surgical
c) Surgical
 Smoking cessation
 Head elevation (night) and cold
compression (morning)
 Artificial tear
 Eyelid taping
 Guanethidine 5% eye drop
 Systemic steroid
 Radiotherapy
 Combined therapy
 During active phase orbital
decompression
 During inactive phase extraoccular and eyelid
Sx.
Two wall Three wall Four wall
1.)Orbital
floor
2) Medial
wall
Add
roof(lat.
Half) and
sphenoid
at apex.
Add
Lateral
wall
 Recession surgery is done
 Mc= inferior rectus recession
 Mullerectomy-
 Levator recession-
 Scleral graft with LPS-
 Blepharoplasty-
Exophthalmos
Exophthalmos
Exophthalmos

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Exophthalmos