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Cost of intramuscular versus oral vitamin B12 in Primary Care
![Cost of intramuscular versus oral vitamin B12 in Primary Care Josep Vidal-Alaball, Christopher C Butler and Christopher Potter Department of General Practice / Department of Epidemiology, Statistics and Public Health, University of Wales College of Medicine, Cardiff ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Preliminary results Cost of resources used in parenteral treatment compared with oral treatment: References 1. van Walraven C, Naylor C. Use of vitamin B12 injections among elderly patients by primary care practitioners in Ontario. Canadian Medical Association Journal 1999;161:146-9. 2. Rickes E, Brink N, Koniuszy F, Wood T, Folkers K. Crystalline vitamin B12. Science 1948;107:396. 3. Spies T, Stone R, Lopez G, Milanes F, Toca R, Aramburu T. Vitamin B12 by mouth in pernicious and nutritional macrocytic anaemia and sprue. Lancet 1949;2:454-6. 4. Ross G, Mollin D, Cox E, Ungley C. Hematologic responses and concentration of vitamin B12 in serum and urine following oral administration of vitamin B12 without intrinsic factor. Blood 1954;9:473-88. 5. Berlin H, Berlin R, Brante G. Oral treatment of pernicious anemia with high doses of vitamin B12 without intrinsic factor. Acta Medica Scandinavica 1968;184(4):247-58. 6. Berlin R, Berlin H, Brante G, Pilbrant A. Vitamin B12 body stores during oral and parenteral treatment of pernicious anaemia. Acta Medica Scandinavica 1978;204(1-2):81-4. 7. Norberg B. Oral high-dose cyanocobalamin - a contagious concept. Rondel , 2001. 8. Lederle FA. Oral cobalamin for pernicious anemia. Medicine's best kept secret? Journal of the American Medical Association 1991;265(1):94-5. 9. Middleton, J. and Wells, W. Vitamin B12 injections: considerable source of work for the district nurse, British Medical Journal Clinical Research Ed 1985; 290 : 1254-5. Effectiveness estimation We have conducted a systematic review on the use of oral vitamin B 12 for the treatment of vitamin B 12 deficiency. The review concluded that oral vitamin B 12 is a effective as intramuscular vitamin B 12 in treating vitamin B 12 deficiency. ,[object Object],[object Object],[object Object],SAPC, Glasgow 2004 =](https://image.slidesharecdn.com/cmaposterjvidal-alaball-091122184653-phpapp01/85/cost-of-intramuscular-versus-oral-vitamin-b12-in-primary-care-1-320.jpg)
