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Provider performance in
  treating poor patients -
    factors influencing
 prescribing practices in
Lao PDR: a cross-sectional
           study
  Regional Forum on Health Care Financing
   2-4 May 2012, Phnom Penh, Cambodia
              By: Lamphone Syhakhang
        Deputy Director of FDD, MoH, Lao PDR
Background
• High out-of-pocket payments of medical care
  spending at hospitals in Laos, thereby putting poor
  households at risk of catastrophic health expenditure
• Main financing mechanism is revolving drug fund
  whereby providers can sell drugs at purchase price
  with 25% profit margin
• Social security schemes have newly been introduced
  in some parts of Laos, and Drug and Therapeutic
  Committees have been established to ensure
  Rational Use of Medicines and to improve quality of
  care
• Control mechanisms formulated but insufficiently
  enforced.
Objectives
- To assess direct and indirect medical costs
  for hospitalizations at district and
  provincial hospitals
- To assess appropriateness of use of
  medicines
Study design & study
         population
• Cross-sectional study using four tracer
  conditions for data collection: a) major injury,
   b) hypertension, c) post-delivery haemorrhage,
  and d) pneumonia in children under five.
• Conducted in 12 hospitals (3 provincial hospitals
  and 9 district hospitals) in three provinces
  (Luangprabang, Vientiane and Savannakhet)
• In total 828 patients were selected consecutively
  according to the time of their admission to the
  hospital.
Methods
• Structured interviews with 828 in-patients at
  twelve provincial and district hospitals on
  expenditures for treatment ,direct non-medical
  costs (transport, food, lodging), including
  informal payment.
• Evaluation of each patient’s medical record for
  appropriateness of drug use using a checklist of
  treatment guidelines (maximum score = 10)
Results – patients with
    different income levels
• No significant differences regarding quality of
   treatment for patients at different income levels
   (low, medium and high):
- the scores for appropriate drug use: 5.0, 4.8 and
   4.8, p=0.71
- The average number of antibiotic injections
   0.87, 0.93 and 0.94, p=0.63
- total cost of medicines LAK 319 645, 324 685,
   and 370 855, p=0.85
• However, the high-level income patients paid
   fees 3 times more than others (p<0.0001).
Results – insured and
      uninsured patients
• A significant higher score for appropriate drug use
  in insured patients than uninsured patients (5.9 vs
  4.9 p=0.0001).
• Insured patients received significantly fewer
  medicines in total and also fewer antibiotics
  compared with uninsured patients (0.52 vs 0.98,
  p<0.0001).
• Insured patients also stayed fewer days in hospital
  (2.7 vs. 3.7) and paid significantly less for
  medicines (USD 14.8 vs. 43.9) and diagnostic
  tests (USD 5.9 vs. 9.2) than uninsured patients
Use of medicines, diagnostic tests and costs in LAK* for uninsured and insured patie

  Description                                    Insurance
                                                 Mean (SD)              p-value
                                            No              Yes
                                           N=712           N=116
  Appropriate drug use score                 4.9(2.7)        5.9(2.7)    0.0001
  Total number of medicines during           5.4(2.5)        5.2(3.2)      0.04
  hospital stay
  - Number of antibiotic injections         0.98(0.89)       0.52(0.86) <0.0001
  - Number of oral antibiotics              0.49(0.58)       0.37(0.68)   0.011
  - Number of essential medicines              4.6(2.1)         4.6(2.6)   0.14
  - Number of brand drugs                      1.3(1.4)         1.2(1.3)   0.54
  Average duration of stay (days)              3.7(4.4)         2.7(3.3)  0.002
  Cost of medicines (in LAK)                   373 060          126 063   0.001
                                             (772 660)        (267 340)
  Cost of diagnostic tests (in LAK)             77 826           50 146    0.02
                                             (123 104)         (54 929)
  Other costs (in LAK)                         360 608          240 745     0.11
                                             (563 086)        (394 973)
  Fee charge (in LAK)                           53 308           43 166    0.74
* LAK = Lao KIP; 1 USD = 8 500 LAK           (105 995)         (89 158)
Results – patients at provincial
    and district hospitals
• The score for appropriate use of medicines was
  significantly higher at district hospitals than at
  provincial hospitals (5.3 vs. 4.8, p=0.01)
• The use of medicines for patients at provincial level
  was also significantly higher than for patients at
  district level in terms of average number of
  medicines prescribed (6.8 vs. 4.5, p<0.0001),
  number of antibiotics injections (1.3 vs. 0.7,
  p<0.0001) and number of essential medicines (5.7
  vs.3.9, p<0.0001) , as well as number of days in
  hospital (6.6 vs.1.7, p<0.0001).
Results – patients at provincial
     and district hospitals
              Provincial Hospitals   District Hospitals
   Costs            (LAK*)                 (LAK)        p-value
               Means        SD       Means         SD
Medicines      740,350 1,061,000       113,100 239,103 <0.0001

Diagnostic      95,478    139,967       47,023    71,503 <0.0001
test
Other Costs    532,770    693,214     203,602    338,480 <0.0001

Fee charges     60,780    103,764       47,430   105,474 0.67

Total         1,429,378                411,155

* LAK = Lao KIP; 1 USD = 8 500 LAK
Results – patients with
different tracer conditions
   and informal payment
• A significant lower score for appropriate use of
  medicines in patients with major injury and post-
  delivery haemorrhage (3.7 and 3.8, respectively),
  than in patients with hypertension (5.8) and in
  children with pneumonia (7.1) (p<0.0001)
• Patients who made informal payments had a
  significantly lower score for appropriate use of
  medicines than those not making informal
  payments (5.1 vs 3.5, p=0.0001).
Factors influencing
    prescribing practices
• A higher total cost for medicines and diagnostic
  tests was associated with uninsured patients,
  patients with higher education, patients making
  informal payments, patients treated in a
  provincial hospital and patients in the lowest
  income-level group
• There was no association found with sex,
  profession and distance from health facility.
Suggested factors influencing provider performance in terms of total cost for
 medicines and diagnostic tests in LAK*, multiple linear regression analysis
(R-squared = 0.29).
     Suggested factors         beta     Standard p-value      95% confidence
                            coefficient deviation                  limits
 Sex                           -58 571     50 455   0.246     (-157 625; 40 482)
 0=female, 1=male
 Education                    117 142     59 380      0.049      (568; 233 715)
 0= low, 1=high
 Income                      -139 999     52 653      0.008 (-243 366; -36 632)
 0= low, 1=high
 Hospital level              -578 531     52 880    <0.001 (-682344; -474 717)
 0=provincial, 1=district
 Insurance                   -178 853     71 359      0.012 (-318 943; -38 763)
 0= no insurance,
 1= insurance
 Informal payment             681 790     74 142    <0.001 (536236; - 827 344)
 0= no informal payment
 1= with informal
 payment
Conclusions
• Use of medicines and cost of care at hospitals in
  Laos were more appropriate for insured patients
  regardless of level of income, this can help reduce
  the number of households experiencing catastrophic
  health expenditure
• Difference in cost for the same treatments according
  to leave of care (province vs. district hospital)
• Insurance schemes will lower risk for catastrophic
  health expenditure if implemented cautiously
• Support from well-functioning Drug and Therapeutics
  Committees is essential
Thank you

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Laos: Hospital treatment costs and tertiary care

  • 1. Provider performance in treating poor patients - factors influencing prescribing practices in Lao PDR: a cross-sectional study Regional Forum on Health Care Financing 2-4 May 2012, Phnom Penh, Cambodia By: Lamphone Syhakhang Deputy Director of FDD, MoH, Lao PDR
  • 2. Background • High out-of-pocket payments of medical care spending at hospitals in Laos, thereby putting poor households at risk of catastrophic health expenditure • Main financing mechanism is revolving drug fund whereby providers can sell drugs at purchase price with 25% profit margin • Social security schemes have newly been introduced in some parts of Laos, and Drug and Therapeutic Committees have been established to ensure Rational Use of Medicines and to improve quality of care • Control mechanisms formulated but insufficiently enforced.
  • 3. Objectives - To assess direct and indirect medical costs for hospitalizations at district and provincial hospitals - To assess appropriateness of use of medicines
  • 4. Study design & study population • Cross-sectional study using four tracer conditions for data collection: a) major injury, b) hypertension, c) post-delivery haemorrhage, and d) pneumonia in children under five. • Conducted in 12 hospitals (3 provincial hospitals and 9 district hospitals) in three provinces (Luangprabang, Vientiane and Savannakhet) • In total 828 patients were selected consecutively according to the time of their admission to the hospital.
  • 5. Methods • Structured interviews with 828 in-patients at twelve provincial and district hospitals on expenditures for treatment ,direct non-medical costs (transport, food, lodging), including informal payment. • Evaluation of each patient’s medical record for appropriateness of drug use using a checklist of treatment guidelines (maximum score = 10)
  • 6. Results – patients with different income levels • No significant differences regarding quality of treatment for patients at different income levels (low, medium and high): - the scores for appropriate drug use: 5.0, 4.8 and 4.8, p=0.71 - The average number of antibiotic injections 0.87, 0.93 and 0.94, p=0.63 - total cost of medicines LAK 319 645, 324 685, and 370 855, p=0.85 • However, the high-level income patients paid fees 3 times more than others (p<0.0001).
  • 7. Results – insured and uninsured patients • A significant higher score for appropriate drug use in insured patients than uninsured patients (5.9 vs 4.9 p=0.0001). • Insured patients received significantly fewer medicines in total and also fewer antibiotics compared with uninsured patients (0.52 vs 0.98, p<0.0001). • Insured patients also stayed fewer days in hospital (2.7 vs. 3.7) and paid significantly less for medicines (USD 14.8 vs. 43.9) and diagnostic tests (USD 5.9 vs. 9.2) than uninsured patients
  • 8. Use of medicines, diagnostic tests and costs in LAK* for uninsured and insured patie Description Insurance Mean (SD) p-value No Yes N=712 N=116 Appropriate drug use score 4.9(2.7) 5.9(2.7) 0.0001 Total number of medicines during 5.4(2.5) 5.2(3.2) 0.04 hospital stay - Number of antibiotic injections 0.98(0.89) 0.52(0.86) <0.0001 - Number of oral antibiotics 0.49(0.58) 0.37(0.68) 0.011 - Number of essential medicines 4.6(2.1) 4.6(2.6) 0.14 - Number of brand drugs 1.3(1.4) 1.2(1.3) 0.54 Average duration of stay (days) 3.7(4.4) 2.7(3.3) 0.002 Cost of medicines (in LAK) 373 060 126 063 0.001 (772 660) (267 340) Cost of diagnostic tests (in LAK) 77 826 50 146 0.02 (123 104) (54 929) Other costs (in LAK) 360 608 240 745 0.11 (563 086) (394 973) Fee charge (in LAK) 53 308 43 166 0.74 * LAK = Lao KIP; 1 USD = 8 500 LAK (105 995) (89 158)
  • 9. Results – patients at provincial and district hospitals • The score for appropriate use of medicines was significantly higher at district hospitals than at provincial hospitals (5.3 vs. 4.8, p=0.01) • The use of medicines for patients at provincial level was also significantly higher than for patients at district level in terms of average number of medicines prescribed (6.8 vs. 4.5, p<0.0001), number of antibiotics injections (1.3 vs. 0.7, p<0.0001) and number of essential medicines (5.7 vs.3.9, p<0.0001) , as well as number of days in hospital (6.6 vs.1.7, p<0.0001).
  • 10. Results – patients at provincial and district hospitals Provincial Hospitals District Hospitals Costs (LAK*) (LAK) p-value Means SD Means SD Medicines 740,350 1,061,000 113,100 239,103 <0.0001 Diagnostic 95,478 139,967 47,023 71,503 <0.0001 test Other Costs 532,770 693,214 203,602 338,480 <0.0001 Fee charges 60,780 103,764 47,430 105,474 0.67 Total 1,429,378 411,155 * LAK = Lao KIP; 1 USD = 8 500 LAK
  • 11. Results – patients with different tracer conditions and informal payment • A significant lower score for appropriate use of medicines in patients with major injury and post- delivery haemorrhage (3.7 and 3.8, respectively), than in patients with hypertension (5.8) and in children with pneumonia (7.1) (p<0.0001) • Patients who made informal payments had a significantly lower score for appropriate use of medicines than those not making informal payments (5.1 vs 3.5, p=0.0001).
  • 12. Factors influencing prescribing practices • A higher total cost for medicines and diagnostic tests was associated with uninsured patients, patients with higher education, patients making informal payments, patients treated in a provincial hospital and patients in the lowest income-level group • There was no association found with sex, profession and distance from health facility.
  • 13. Suggested factors influencing provider performance in terms of total cost for medicines and diagnostic tests in LAK*, multiple linear regression analysis (R-squared = 0.29). Suggested factors beta Standard p-value 95% confidence coefficient deviation limits Sex -58 571 50 455 0.246 (-157 625; 40 482) 0=female, 1=male Education 117 142 59 380 0.049 (568; 233 715) 0= low, 1=high Income -139 999 52 653 0.008 (-243 366; -36 632) 0= low, 1=high Hospital level -578 531 52 880 <0.001 (-682344; -474 717) 0=provincial, 1=district Insurance -178 853 71 359 0.012 (-318 943; -38 763) 0= no insurance, 1= insurance Informal payment 681 790 74 142 <0.001 (536236; - 827 344) 0= no informal payment 1= with informal payment
  • 14. Conclusions • Use of medicines and cost of care at hospitals in Laos were more appropriate for insured patients regardless of level of income, this can help reduce the number of households experiencing catastrophic health expenditure • Difference in cost for the same treatments according to leave of care (province vs. district hospital) • Insurance schemes will lower risk for catastrophic health expenditure if implemented cautiously • Support from well-functioning Drug and Therapeutics Committees is essential