gpat 2020 prepaeration

1. Memory based questions from GPAT 2020
1. Mesh size in lycopodium spore method is ....?
2. The pungency of zingiber rhizomes due to which components?
3. pH calculation by Henderson hasselbatch 0.1M NaOH 50ml in 100ml 0.1M
ch3cooH..pka acetic acid was given
4. What is SFI index full form?
5. What is the HPMC use?
6. What is Biological source of shellac?
7. Wolf Kisner reaction was given ...… identification of that reaction
8. HNO3+H2So4 =?
9. Size of lycopodium spores
10.Aneurysm is ....?
11.Amylopectin reacts with iodine gives ….. colour?
12.Clotting factors activated by Vitamin K is ....?
13.Identify the reaction order given (there may be the 2nd order equation)
14.Calculation of Css I.V…equation (from biopharmaceutics section)
15.Scavenger cell also called?
16.Graves disease causes?
17.Identify Alpha 1 blockers?
18.Characteristics of microemulsion are ...?
19.Pair of alpha2 blockers
20.Timolol structure
21.Van gierks disease occurs due to?
22.Hospital formulary question
23.Medline databases are?
24.Identify false statement on Calcitrol
25.5 alpha-reductase inhibitor?

2. 26.What is ELISA
Identify differentiated product from paracetamol, Zantac, ranitidine, isoniazid
27.pM indicators used in ??
28.Non-Newtonian viscometer
29.Travellers diarrhoea treated with?
30.Which one of the following is not anti Tb drug ( streptomycin, gentamicin,
isoniazid, clotrimazole )
31.What is Suture?
32.Avicel also know as?
33.Carboxymethyl cellulose used as in tablet?
34.Purpose of barometric leg in jet condenser?
35.Uses of the chemical compound obtained from red scill ( rodenticide )
36.Is microscopy observed in Alzheimer’s disease?
37.To identify a protein, which probe is used?
38.Soda ash also called as?
39.1. MTP forms – owner of place
2. Patent office – Mumbai, Chennai & delhi
3. Cannabis penalty – 10 yrs + 1 lakh fine
4. Pharmacy act – Education course & examination conduct
5. Differentiated product – Zantac
6. Two or more brand loyal – Shifting Loyal
7. Barometer leg – To remove excess steam/solvent
8. Hardinge mill – Ball mill
9. Absorptivity & emissivity relation – Stevan Boltzman equation
10. Elisa principle – Antigen-Antibody reaction
11. ProteinProbe – Antibody
40.12. Cassia angustifolia in draught condition – Increase Sennosides A + B
13. Antiviral Neem – Nimbin
14. Rheoholarrhina A-F – Kurchi
15. Gambier Fluorescence – Green
16. Shellac Source – Aviera lacca
17. Lycopodium spore size – 25 micrometer
18. Cone like, pointed shrubs & trees – Coniferous
19. Ginger pungency – Gingerol

3. 20. Red Squill – Rodenticide
21. Pyrethrum Cultivation – Kenya/India
41.22. OECD guidelines for toxicity studies – Fixed dose combination
23. Excessive use of diuretics causes – Hypovolemic Shock
24. Beta 2 agonist when not given inhalation route shows side effect of –
Fine tremors
25. Metabolic process not affected in weight loss
26. Not the property of nitric oxide – platelet aggregation
27. Graves disease – Thyrotoxicosis
28. Vitamin D true statement except – Calcium reabsoprtion from bones
29. Suture in bone – Skull
30. Aneurysm – Bulge in artery
31. Cardiac output – Volume of ventricular ejection per minute
32. Drug used for factor Xa – Rivaroxaban
33. Vitamin K coenzyme for factors – II, VII, IX, X
34. Most metabolizing CYP enzyme – 3A4
35. Erythromycin coadministration effect – Increase Bio availability by
inhibiting enzyme
36. Not true for benzodiazepine – causes convulsion
37. Alzheimer’s disease cause – beta amyloid
38. Haemotocrit value >65% – polycythemia
39. Drug not used in treatment of YB – Gentamicin
40. Metabolic acidosis not caused in – wound healing
41. Scavengers cells – Macrophages
42. Migration of cells under inflammation – Chemotaxis
43. Not a function of glucocorticoids – Sensitize immune response
44. Not a muscarinic function – reflex tachycardia
45. Travellers diarrhoea – Sulphamethoxazole + trimethoprim
46. Alpha blocker – prazosin
47. Synovial fluid impaired – decrease in hylarunic acid
48. Match the following (cholethiasis – bile, stestosis – fat cell)
49. Bilirubin retention cause – decrease clearance of bile
50. Anticonvulsant drug increases GABA and Decreases Glutamate –
Valproate (topiramate)
51. Estrogen/progesterone balance deficiency in enzyme for decrease in
serotonin and dopamine – tryptophan hydroxylase (enzyme decarboxylase)
52. 5 alpha reductase inhibitors – finasteride
53. Von-gierks disease – glucose-6-phosphate
53. Beta oxidation deficiency causes – Sudden infant death
54. Anti emetic function of glycopyrrolium due to – M1
55. Protective layer on stomach mucosa – Sucralfate
56. Anaplasia – Morphological differentiation from other cells
42.57. Anti addition of bromine to trans alkene – meso product
58. Reaction of converting carbonyl to alkane in alkaline condition – wolf
kishner

4. 59. Reduction Reaction catalyzed by NH2-NH2 – wolf kishner
60. E1 elimination of neo-pentyl bromide – 2-methyl-butene
61. Soda ash – Sodium carbonate
62. Dakin solution – Sodium hypochlorite
63. HNO3 + H2SO4 – H3O+ + 2HSO4- + NO2+
64. Amine protectiongroup – t-BOC
65. Which diacid not forms anhydride – Fumaric acid
66. Conjugation Reaction forming alpha-beta-ester – Darzen’s reaction
67. Doxorubicin contains which ring – Anthracene and cyclohexane ring
68. Beta blocker Structure – None option matches given structure
69. Timolol contains which ring – 1,2,5-thiadiazide ring
70. Alanine and proline ACE inhibitors – Enalapril
71. Amylopectin color reaction with iodine – Red purple
72. PM indicators – Complexometric titrations
73. Compound having no dipole moment – CO2
74. Band due to Nujol is due to – C-Hstr and C-Hdef
75. Cardioselective beta blocker – Nevibolol
76. Glass type II, volumetric flask 1000 ml limit –
77. NaOH (50 ml) and CH3COOH (100 ml), Ka of acetic acid given, pH of
resultant solution –
78. Heat of vaporization for water given calculation –
79. Freezing point depression calculation –
80. Highest Thermal conductivity gas – Helium
81. UV absorption value due to Pi-Pi bond – 237 nm
82. AAS steps as per Nebulization and Desolvation –
83. Strongest to weakest order towards electrophilic aromatic substitution –
N(R)3 > NHCOR > C6H5 > I
43.84. 21 CFR 211 is for – GMP
85. NDA filing with S and P – Standard and Priority
86. HLB calculation – A-1.4 and B-5.6
87. Css for one compartment model – (Cmax) × (infusion rate) / Clearance
88. Fluid flow per unit time to a tissue – perfusion rate
89. Aerosol valve acceptance limit – 15%
90. Microcyrtalline celluose – Avicel
91. In tablets, HPMC use – Binder
92. Non-newtonian system apparatus – Cup and bob
93. Hospital formulary benefit – Avoid duplicacy of brand
94. Highest MP – stable
95. Polymorphism detection technique – DSC
96. Medline, Embase use – Database
97. Order of reaction for twice dependability – 2nd order
98. Roll over technique modification –
99. Glassware for pyrogen free – Autoclave for 15 min
100. Paediatric bitter solution flavour – orange syrup
101. SFI full form – solid fat index
102. Not a emulsification theory – phase inversion

5. 103. Microemulsion true statement – forms gel on exaggerated conditions
104. Migration of solid under influence of potential – electrophoresis
105. Two brand product having same clinical effects – therapeutic
equivalence
106. Which oxide not added in amber glass
107. Shake well label for – opthalmic suspensions
108. Phase contrast Microscopy – fluorescent dye
109. Concentration of IgG administered –
110. GMP guidelines for human and veterinary drugs aaplicable for –
manufacturing, holding and packaging
111. Not true for bulkiness – Smaller particle entrapped in pores
112. Leaching of solid in solvent – maceration
113. Not a principle for Gastro retentive delivery system – Osmosis
114. Phase solubility of liquids not a method for – Bio availability studies
115. Volume-diameter given, density given, number of particles calculation –
44.116. Diazonium salt to halides conversion catalyst – Cu(II)
117. Catalytic activity RNA – ribozyme
118. 6-APA + p-hydroxy-benzyl-glycine – amoxicilin