2. Mrs. ABC, 65/F
DOA- 25/02/2018
12: 00 AM
DOD- 25/02/2018
11:00 AM
3. Background history
Recently diagnosed as
RHD- Severe MR, mild AR,Severe PAH, Mild LV
dysfunction, EF 50%.
AF with LBBB (CVR)
NYHA III.
Was seen in OPD one week back and started on
metoprolol 25mg od , glyceryl mononitrate 30 mg SR,
enalapril 2.5mg, warfarin 3mg.
Complained of general weakness- since 7 am in the
morning.
Sought no medical help initially
4. Presented to ED AIIMS at 11:15 Pm
Initial clinical exam:
concious, disoriented
Pulse 36/min, BP 76/50, RR 36/min, SpO2 88% on
ambient air
Chest- B/L vesicular breath sounds. Crepts (R) ISA
CVS- S1, S2 normal, systolic murmrer at apex
10. Post TPI patient continued to be in shock, on triple
inotropes- adrenaline, Noradrenaline and Dopamine.
Echo- severe MR,Mild LV dysfunction EF 50%
Hb 10.2g/dL
TLC 14800/mm3
DLC N80% L12%
Urea 55 mg/dL
Creatinine 2.8 mg/dL
11. Down Hill Course continued in CCU
Patient continued to deteriorate
Patient received inj Augmentin and Inj Levofloxacin.
Inotropic drug requirement continued to increase
In the morning at arround 10 am patient developed
cardiac arrest, monitor revealed asystole, pacing spikes
with no capture.
CPR was given for about 30 mins and patient was
declared dead at 11 am.
12. Final diagnosis
Refractory cardiogenic shock with severe bradycardia-
CHB with Ventricular escape rythm
?Septic Shock
Source ? chest
?Drug toxicity
Beta blocker/ Nitrates
13. Could it have been better managed????
Was medical therapy in OPD over-aggressive since
such patients have no monitoring at home????
Could it be sepsis on top of cardiac disease????
Should we have tried inj Glucagon????
Or was it very late presentation as she presented with
severe lactic acidosis!!!!
Was it terminal bradycardia!!!!!