Complex chronic patients (CCPs), defined as patients with two or more chronic diseases who are elderly and consume a high level of healthcare resources, represent 5% of the population but account for over 40% of hospital admissions. The CONNECARE project aims to develop and evaluate an integrated care model supported by technological solutions to better coordinate care and enable self-management for CCPs. Clinical trials will be conducted in Spain, Israel, and the Netherlands to assess the health benefits of the CONNECARE solution and generate guidelines to transfer the model to other healthcare systems.