Zap-CHO is a new class of supplement that provides FBS-like performance.
1.23.09 CD medium C; 1.8 g/L Zap-CHO
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Maximize CHO Cell Culture Performance with InVitria\'s Zap-CHO
Zap-CHO Media Supplement Maximizes the Growth and Productivity of CHO Cells<br />Steve Pettit, Ph.D<br />Director of Cell Culture Development<br />InVitria<br />www.InVitria.com Info@Invitria.com<br />(800) 916-8311<br />
What is Zap-CHO?<br />Zap-CHO is:<br />A combination of defined recombinant proteins that maximize CHO growth and productivity<br />Well defined and consistent from lot-to-lot<br />Cost effective<br />A FBS replacement for performance - without the animal source<br />ZAP-CHO is NOT:<br />A hydrolysate<br />
Zap-CHO is Effective Across Media Types<br />Relative Increase in Productivity<br />820 810<br /> Protein Free Serum Free Chemically Defined Serum Free Protein Free Chemically Defined<br />
Improved Growth Kinetics of CHO with Zap-CHO <br />10% FBS<br />No Additive<br />
Average Increase in Growth and Productivity<br />*InVitria tests comparing the performance of Zap-CHO vs. hydrolysates and IGF1 show that Zap-CHO outperforms both of these supplements.<br />
Zap-CHO Proteins are Removed by Protein A<br />Reducing SDS-PAGE<br />75 KDa -<br />Heavy Chain<br />50 Kda -<br />Light Chain<br />25 Kda -<br />
Advantages & Applications of Zap-CHO<br />Advantages<br /><ul><li>Faster cell growth
Removed by Protein A column during downstream purification</li></ul>Applications<br /><ul><li>Clone selection – Improve growth and shorten timelines
Seed train expansion – Shorten time from cell bank to bioreactor
Cell adaptation– Shorten timelines for media adaptation
Bioproduction– Maximize antibody titre</li></li></ul><li>To Learn More About Zap-CHO<br />To Request a Zap-CHO Scientific Poster or to Order a Sample of Zap-CHO <br /><ul><li>Online: www.zapcho.com