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Controversia tratamiento dislipemias
1.
2. 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce
Atherosclerotic Cardiovascular Risk in Adults
A Report of the American College of Cardiology/American Heart Association Task Force on
Practice Guidelines (November 2013)
GRUPO 1.- ENFERMEDAD CARDIOVASCULAR:
ALTA INTENSIDAD SI EDAD < 75 A.
MODERADA INTENSIDAD SI > 75 A.
Trat. Alta-Intensidad con Estatinas
Atorvastatin (40†)–80 mg
Rosuvastatin 20 (40) mg
GRUPO 2.- PACIENTES CON LDL > 190 mg / ml
ALTA INTENSIDAD
GRUPO 3.- DIABETICOS DE 40-75 a. LDL 70-189
ALTA INTENSIDAD SI RCV > 7,5 %
INTENSIDAD MODERADA SI RCV < 7,5 %
GRUPO 4.-PACIENTES LDL >70 mg% Y RCV >7,5 %
ALTA INTENSIDAD CON RCV > 7,5 %
MODERADA INTENSIDAD 5-7,5 %
Trat. Moderada Intensidad Estatinas
Atorvastatin 10 (20) mg
Rosuvastatin (5) 10 mg
Simvastatin 20–40 mg‡
Pravastatin 40 (80) mg
Lovastatin 40 mg
Fluvastatin XL 80 mg
Fluvastatin 40 mg bid
Pitavastatin 2–4 mg
3. In an article published November 18, 2013 in the New York
Times , two physicians testing the accuracy of the new risk
calculator developed by the American College of
Cardiology(ACC) and American Heart Association (AHA)
found that it vastly overestimated patient risk. Drs Paul
Ridker and Nancy Cook (Brigham and Women's Hospital,
Boston, MA) calculated the 10-year risk of cardiovascular
events in three large-scale primary prevention cohorts—
the Women's Health Study(WHS), the Physicians' Health
Study (PHS), and theWomen's Health Initiative
Observational Study (WHI-OS)—”SOBRESTIMA
RCV ENTRE EL 75% AL 150%”
EL
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5.
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7. European Guidelines on cardiovascular disease prevention in clinical
practice (version 2012)
European Heart Journal Advance Access published May 3, 2012