11. Side effects of antithyroid
drugs
Minor
Skin reactions 4–6% Urticarial or macular reactions
Arthralgias 1–5% May be harbinger of more severe
arthritis
Gastrointestinal effects 1–5% Includes gastric distress and nausea
Abnormal sense of taste
Polyarthritis 1–2% So-called antithyroid arthritis syndrome
13. Hyperthyroidisms in pregnancy
Only 0.2 -0.4 % case
Due to geave’s disease ,toxic nodules, thyroditis.
Risk- Low birth weight, pre-eclemsia
Choice of treatment –Medical management
- surgical after 2nd
trimester
Drugs of choice - Propylthiouracil