1. IVMS BMS GENERAL PRINCIPLES USMLE WEB MAPS
COMPONENT VI: GENERAL PATHOLOGY: PATHOGENESIS AND
BIOLOGY OF TISSUE RESPONSE TO DISEASE deals with
inflammation (cells & mediators), reparative process and the
basic concepts in neoplasia including carcinogenesis, tumor
immunology and cancer epidemiology, prevention and control.
6.1. INFLAMMATION (CELLS AND MEDIATORS)
IVMS-General Pathology- Inflammation PPt.
http://ocw.tufts.edu/Course/51/lecturenotes
WebPath-Inflammation Index HTML. Page
(excellent, most comprehensive pathologic basis of inflammation – highly recommended)
http://en.wikipedia.org/wiki/Inflammation
Acute inflammation and mediator systems (pharmacologic mediators)
IVMS-Anti-Inflammatory and Autacoid Pharmacology- NSAIDs
Vascular response to injury (including mediators) Inflammatory cell recruitment (adherence and
cell migration) and phagocytosis
http://mayoresearch.mayo.edu/vmiller_lab/endothelial.cfm
Bactericidal mechanisms and tissue injury
Clinical manifestations (including pain, fever, leukocytosis, leukemoid reaction, and chills)
http://www.epathoplus.com/inflammation.htm
Chronic inflammation
CHRONIC INFLAMMATION AND WOUND HEALING
IVMS Inflammation Notes
6.2. REPARATIVE PROCESSES
Inflammation and Repair Illustrated Lectures
IVMS BMS GENERAL PRINCIPLES USMLE WEB MAPS
COMPONENT VI: GENERAL PATHOLOGY: PATHOGENESIS AND BIOLOGY OF TISSUE RESPONSE TO
DISEASE

2. Wound healing, hemostasis, and repair: thrombosis, granulation tissue, angiogenesis, fibrosis,
and scar/keloid formation
http://en.wikipedia.org/wiki/Wound_healing
How wounds heal and tumors form
Regenerative processes
6.3. NEOPLASIA
http://www.pathguy.com/lectures/unknown.htm
http://edcenter.med.cornell.edu/CUMC_PathNotes/Neoplasia/Neoplasia_01.html (excellent
classification of neoplasm)
Classification, histologic diagnosis
http://clinlabs.path.queensu.ca/present/dexter/oldneoplasia/
http://www.vet.purdue.edu/vpb/clinpath/vpb555/555cyt3/sld033.htm
Grading, and staging of neoplasms
http://www.unc.edu/courses/2001fall/biol/008/001/day25/neo5.ppt (Biology & epidemiology of
cancer)
Cell biology, biochemistry, and molecular biology of neoplastic cells: transformation, oncogenes,
altered cell differentiation, and proliferation
http://edcenter.med.cornell.edu/CUMC_PathNotes/Neoplasia/Neoplasia_04.html
Hereditary neoplastic disorders
Invasion and metastasis (mechanism & subtypes)
http://www3.mdanderson.org/DEPARTMENTS/liver/images/method.jpg biologic mechanism of
metastasis
http://www.path.sunysb.edu/courses/im/
Tumor immunology
http://www.merck.com/pubs/mmanual/section11/chapter143/143a.htm
http://www.mcl.tulane.edu/classware/pathology/medical_pathology/New_for_99/tum_immu/
Paraneoplastic manifestations of cancer
IVMS-Gen Tumors, Host and Paraneoplastic Syndromes
http://www.urotext.com/pages/PNSs.html
http://www.cancernetwork.com/home/frames.htm?http://www.cancernetwork.com/handbook/em
ergencies.htm&3
IVMS BMS GENERAL PRINCIPLES USMLE WEB MAPS
COMPONENT VI: GENERAL PATHOLOGY: PATHOGENESIS AND BIOLOGY OF TISSUE RESPONSE TO
DISEASE

3. Cancer epidemiology, control and prevention
http://www.pitt.edu/~super1/lecture/lec0192/
PLEASE REPORT BROKEN LINKS TO DR. CRAY drcray@imhotepvirtualmedsch.com
IVMS BMS GENERAL PRINCIPLES USMLE WEB MAPS
COMPONENT VI: GENERAL PATHOLOGY: PATHOGENESIS AND BIOLOGY OF TISSUE RESPONSE TO
DISEASE