Preclinical CRO performing GLP, Non-GLP, pilot and development testing of medical devices, biotech, pharma, gene therapies, and more. AAALAC accredited facility with highly skilled personnel which can create a large array of research models for chronic or acute testing.

1. Main Facility
Lancaster, MA
Ph: 978-368-3477
Direct Contact
Tony Nazal
978-618-7361
tnazal@davincibiomed.com
www.davincibiomed.com
As a GLP, AAALAC
Accredited Contract
Research Laboratory,
DaVINCI offers a full range
of Preclinical In Vivo
Research Services.
Member
MassMEDIC
NCMD
AALAS
Bringing Art & Innovation together through Scientific Excellence
Accreditation
OLAW

2. Regenerative
Medicine
Cardiovascular
Orthopaedic Pharmacokinetics &
Toxicokinetics
•Drug, Compound
•Dermal
•Article
•Safety
•Efficacy
Acute & Chronic
Studies
Aregulatory environment
supported by Innovation,
Skill, &
a State-of-the-Art Facility.
GLP
Non-GLP
Histology
Pathology
•Medical Device
•Combination Devices
•Telemetry
•Invasive, Minimally
Invasive
•Interventional Radiology
Bringing Art & Innovation together through…Discipline

3. www.davincibiomed.com
Our business has been built on the foundation of establishing relationships with our clients.
In doing so, we are more focused on individual needs versus the needs of the masses.
v Customized service ensures that the details and the demands
of the application are met.
v Focus provides confidence that your research is
in the hands of experienced and knowledgeable staff.
v Responsiveness gives attention to the needs of your
specific study.
v Flexibility represents a service that is truly client
oriented.
Focus
Customized
Responsiveness
Flexibility
Bringing Art & Innovation together through…Customized Service

4. www.davincibiomed.com
Card
iovas
cular
Native &
PTFE
Vascular
Grafts
Angiogenesis
Angioplasty
Arterio-
sclerosis
Thrombosis
All Levels
DVT
Pacing
LVAD AV Block
Filters –
Vena Cava
And Much
More…
Congestive
Heart
Failure
MR
Stenosis
Infarct
One of the highest levels of expertise in the industry, with a State-of-the-Art
application of techniques to insure comprehensive testing.

5. www.davincibiomed.com
Ortho
paedi
c
Bone
Fillers
& Cements
Engineering
Analysis
Bone Defects Prosthetics
Joint
Replacement
Spinal
Prosthetics
Meniscus
Tears
Hardware
Application
And Much
More…
Expertise in applying devices, and materials, provides confidence in the
performance of the projects and the resulting data.

6. www.davincibiomed.com
Regen
erativ
e
Sutures,
Staples
Adhesives
Skin Grafts,
Wound
Healing
Antimicrobial
Coatings
Dermal
Applications
Closure
Devices
Artificial
Organs
And Much
More…
Critical
Trauma
Astrong knowledge base, and experience with various regenerative and tissue
engineered models, offers a unique skill set surgically and in postoperative care.

7. www.davincibiomed.com
Pharma
co-Toxic
okinetic
s
LD50
PK
Characterization
Infusion
Studies
Interspecies
Scaling
Pharmaco-
dynamics
Pre-
Instrumented
Models
And Much
More…
In Vivo
Metabolism
Telemetry
Data
Collection
Insight & efficiency provide timely implementation and reliable management of
studies.

8. www.davincibiomed.com
Fluoroscopy-
IVUS
Micro-Digital
Photography
Testing
Evaluation
Analysis
Interpretation
Telemetry
3D Ultrasound
See the difference.
Endoscopy
Cardiovascular
Monitoring
Bringing Art & Innovation together through…Imaging

9. Micro-Surgery
Arthroscopic
Surgery
Orthopedic Surgery
- Invasive
Laparoscopic
Surgery
Innovation
Expertise
Experience
Equipment
Meeting the Demands of the Industry.
Telemetry
Implantation
Telemetry
Monitoring
Full Necropsy
w/ Gross Examinations & Analysis
Bringing Art & Innovation together through…Skill

10. www.davincibiomed.com
Mechanical
Testing
Pressure
Torsion
Statistical
Analysis
Separation
Testing
Tension
Fixture
Design
Puncture /
Ball Testing
Experience and efficiency provide our clients reliable data. DaVINCI offers a
higher level of quality.

11. Non-Human Primates
Porcine - Canine
Rodents
-
Rabbits
Hircine
–
Ovine
Bovine
Experience with a large
array of animal models.
Fully enclosed facility
designed to handle large
numbers for chronic
applications.
AAALAC Accredited GLP Facility
Bringing Art & Innovation together through…Knowledge

12. MEDICAL EQUIPMENT
q 3D & 2D Ultrasounds
q DSI Telemetry Monitoring Systems
q COBE Heart Lung Machine/Bypass
q Dragger 4D Anesthesia Machines
(Digital) and more.
q 2-Neuro Vascular Units, OEC 9800
(30fps, 1kx1k resolution, Thermal, X-
ray & DVD Medium
q Pacemaking Units, Medtronics
Programmer FDK
q Endoscopy, Laparoscopy & More….
(Storks 3 Chip Camera)
q Instron System for Material Testing
and analysis.
FACILITIES
q 60,000 sq./ft Operation
q Large, State of Art Surgical Suites
q Animal housing - 200 Plus large
animals
q Sterilization, Low Pressure “ETO”
(Telemetry Sterilization) & Steam
q Specialized Sample Storage,
-80c, -40c & -20c
q Caging for High Volume Studies
for all species
Bringing Art & Innovation together through…State of the Art Facility

13. Knowledge provides understanding, Experience & Skill provide the foundation to apply it correctly.
Contact
Tony Nazal
At 978-618-7361
to learn more about our ability
to take your research to the
next level.
AAALAC Accredited
GLP Facility
Bringing Art & Innovation together through…Knowledge