Stem cells can replace diseased tissue and are used in bone marrow transplants for diseases like leukemia. There are three ways to achieve pluripotency: embryonic stem cells from the blastocyst, reprogrammed stem cells through somatic cell nuclear transfer or induced pluripotency, and induced pluripotent stem cells derived from adult skin cells which provide a complete immunological match for therapy.

1. Stem Cells – State of the ART
Description : Stem cell therapy regenerative medicine: Stem cells replace diseased tissue:
Hematopoietic diseases: Bone marrow transplantation – leukaemia, Pluripotent stem cells –
differentiate into all cell types. Three ways to pluripotency: Embryonic stem (ES) cells: Obtained
directly from inner cell mass of the blastocyst, Reprogrammed stem cells / Nuclear reprogramming:
SCNT somatic cell nuclear transfer, iPS cells induced pluripotency. Pluripotent stem cells and tissue
compatibility: ES cells from embryo- limited immunological match, iPS cells from skin cells-
complete immunological match.
Reference URL: http://medical.wesrch.com/paper-details/pdf-ME1XXFH5NZXDZ-stem-cells-s
tate-of-the-art