4. TRIGEMINAL NERVE
• Largest Cranial Nerve
V1-opthalmic - Passes through Superior Orbital
Fissure
V2- Maxillary – Foramen Rotundum
V3- Mandibular – Foramen Ovale
5.
6. TRIGEMINAL NEURALGIA
• A disorder of the trigeminal nerve (fifth) that causes
episodes of sharp, stabbing pain in the cheek, lips,
gums, or chin on one side of the face.
• Pain seldom lasts more than a few seconds or a minute
or two but may be so intense that patent winces,
hence term tick.
• trigeminal neuralgia gets itsFrench nickname
• ‘tic douloureux’, meaning "painful twitch”.
• • Commonly in middle aged or elderly people
• • F>M
• Incidence 4-8 per 100,000
7.
8. Pathophysiology
• Compression Of Trigeminal Nerve Root By Blood
Vessel( superior cerebellar artery, tortuous)----
Demyelination – Ectopic Generation Of Action
Potential -- Hyperexcitabllity
9.
10. Trigger factor
• Touching
• Washing of face
• Shaving
• Teeth cleaning
• Cold breeze Eating
• Talking
• Application of lotions and cosmetics
14. SURGICAL
• 1. Injection of phenol or alcohol into a
trigeminal ganglion
• 2. Radiofrequency thermal rhizotomy
• 3. Sectioning of sensory root of trigeminal
ganglion inside the cranium
• 4. Microvascular decompression by
suboccipital craniotomy
15.
16. BELLS PALSY
• Most common form of facial paralysis.
• Incidence of idopathic 25 per 100,000
• Risk factor- Pregnancy & DM
17.
18. Clinical Manifestation
• Abrupt onset, maximum weakness at 48 h
• Pain behind ear may precede paralysis for a
day or two.
• Taste sensation may be lost unilaterally
• Hyperacusis may be present
• MRI – Swelling and uniform enhancement of
geniculate ganglion & facial nerve
• 80 % recover within a few weeks or months
19. Pathophysiology
• Mostly reactivation of HSV-1 in geniculate
ganglion
• Reactivation of Varicella Zoster virus (1/3)
• Reported in recipient of intranasal Influenza
vaccine
20. Differential Diagnosis
• Lyme disease (Borrelia burgdorferi) may cause unilateral or bilateral facial
paralysis
• Ramsay Hunt syndrome – severe facial palsy plus vesicular eruption in
external auditory canal
• B/L in Sarcodisis & GBS
• Leprosy
• Facial Neuropathy – in DM, Sjogren syndrome & amyloidosis
• Melkersson-Rosenthal syndrome – Recurrent facial palsy & plication of
tounge
• Acostic neuroma
• Infarct, demyelination lesion of MS & tumor are common pontine lesion
• Tumor invade temporal bone ( carotid body, cholestatoma,dermoid)
• Supranuclear Facial palsy- Frontalis & orbicularis oculi are involved less
than lower part of face , Since upper facial muscle are innervated by
corticobulbar pathways from both motor cortex.
21. LAB DIAGNOSIS
• Diagnosis of BELLS PALSY usually Clinically
• ESR
• Testing of DM
• Lyme titer
• Angiotensing converting enzyme & chest
imaging for Sarcoidosis
• Lumbar Puncture for GBS
• MRI
22.
23. TREATMENT
• Paper tape to depress upper eyelid
• Prednisolone – 60-80 mg daily for 5 days then
taper over next 5 days
• Antiviral – Valacyclovir 1000 mg daily for 5-7
days or Acylovir 400 mg five time daily for 10
days
• Cosmetic surgical procedure for permanantly
paralysis with bells palsy