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SCBU case report
M. BABY 62...
History
A 3min old female term neonates rushed in with APGAR score of 3
Neonates body was covered in meconium, resuscitation was commenced
immediately
Spot at presentation was 70%.
Airway was cleared, meconium sunctioned out and AMBU bagging was
commenced
At 5th minutes of life APGAR became 6
Mothers history
Mother had EMCS on account of obstructed labour
Mother is a 23years old Housewife, unsure of her LMP, however uss put gestation
at 38weeks
Antenatal history were essentially normal
Not a known DM, or HTNsive
Exams finding
She was conscious, pink afebrile anicteric SpO2 88%
Portswine stained, multiple salmon patches covering the body with exfoliating skin
Umbilical cord was found thrombosed : blood filled upto about 7cm, cord is
distended and caliber of vessels seen were abnormally large in diameter
Other exams were essentially normal
Available results
PCV46% RBS 5.1mmol/l
Diagnosis
Respiratory distress of newborn 2 to meconium aspiration
Mild perinatal asphyxia
Umbilical cord thrombosis
Management
IV fluids
Antibiotics
Vitamin K
4th hour of life
Neonates became very pale and breathless
Repeated PCV was 46%
Patient was planned to be transfused
7th Hour of life
She was transfused with sedimented blood at 15ml/kg
SpO2 after transfusion was 64% on oxygen
9th hr of life
Baby was found gasping CPR commenced
Patients died at 12:19am
Discussion
The findings of thrombosed umbilical cord should have changed the outcome
It is a rare complication of pregnancy and delivery
We found few cases reported in journals
Incidence of umbilical cord thrombosis is 1;1500
It is strongly associated with fetal demise and perinatal death
Etiology
Cause is unknown
2 reported cases from St Joseph healthcare ontario Canada found meconium
present in amniotic fluid of the 2 babies raising possibility of vascular insult as a
cause
Associations
Cases found online in journals were associated with
portal vein thrombosis
Ductus arteriosclerosis
Severe protein S deficiency
Intraarterial ischeamic stroke.
Management
Management remains unsolved puzzle to clinicians globally
Despite high mortality there are still survivors especially those that were start early
on low molecular weight heparin at birth
Good outcome depends on
Early detection
Fetal monitoring
Preemptive delivery
Prompt intervention
Conclusion
Umbilical cord thrombosis is a rare event that can lead to neonatal death. When a
baby is delivered with thrombus in the umbilical cord, it may be prudent to
investigate for portal vein thrombosis. Low molecular weight heparin could be
tried. End-organ damage should be considered, and a thrombophilia screen is
also warranted.
Thanks for listening

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SCBU case report.pptx

  • 1. SCBU case report M. BABY 62...
  • 2. History A 3min old female term neonates rushed in with APGAR score of 3 Neonates body was covered in meconium, resuscitation was commenced immediately Spot at presentation was 70%. Airway was cleared, meconium sunctioned out and AMBU bagging was commenced At 5th minutes of life APGAR became 6
  • 3. Mothers history Mother had EMCS on account of obstructed labour Mother is a 23years old Housewife, unsure of her LMP, however uss put gestation at 38weeks Antenatal history were essentially normal Not a known DM, or HTNsive
  • 4. Exams finding She was conscious, pink afebrile anicteric SpO2 88% Portswine stained, multiple salmon patches covering the body with exfoliating skin Umbilical cord was found thrombosed : blood filled upto about 7cm, cord is distended and caliber of vessels seen were abnormally large in diameter Other exams were essentially normal
  • 6. Diagnosis Respiratory distress of newborn 2 to meconium aspiration Mild perinatal asphyxia Umbilical cord thrombosis
  • 8. 4th hour of life Neonates became very pale and breathless Repeated PCV was 46% Patient was planned to be transfused
  • 9. 7th Hour of life She was transfused with sedimented blood at 15ml/kg SpO2 after transfusion was 64% on oxygen
  • 10. 9th hr of life Baby was found gasping CPR commenced Patients died at 12:19am
  • 11. Discussion The findings of thrombosed umbilical cord should have changed the outcome It is a rare complication of pregnancy and delivery We found few cases reported in journals Incidence of umbilical cord thrombosis is 1;1500 It is strongly associated with fetal demise and perinatal death
  • 12. Etiology Cause is unknown 2 reported cases from St Joseph healthcare ontario Canada found meconium present in amniotic fluid of the 2 babies raising possibility of vascular insult as a cause
  • 13. Associations Cases found online in journals were associated with portal vein thrombosis Ductus arteriosclerosis Severe protein S deficiency Intraarterial ischeamic stroke.
  • 14. Management Management remains unsolved puzzle to clinicians globally Despite high mortality there are still survivors especially those that were start early on low molecular weight heparin at birth Good outcome depends on Early detection Fetal monitoring Preemptive delivery Prompt intervention
  • 15. Conclusion Umbilical cord thrombosis is a rare event that can lead to neonatal death. When a baby is delivered with thrombus in the umbilical cord, it may be prudent to investigate for portal vein thrombosis. Low molecular weight heparin could be tried. End-organ damage should be considered, and a thrombophilia screen is also warranted.