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How to decrease Shock Therapy: Present and future of Catheter ablation Thorax Institute. Hospital Clinic University of Barcelona
Why do we need ablation in a patient with ICD’s ,[object Object],[object Object],[object Object],[object Object]
Selection of candidates to VT ablation.  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Decision to ablate depends on: ,[object Object],[object Object],[object Object]
Prophylactic Catheter Ablation for the Prevention of Defibrillator Therapy Reddy et al. N Engl J Med 2007 Decrease the number  of appropriate shocks!
Stevenson et al. Circulation 2008
Present Limitations of VT Ablation ,[object Object],[object Object],[object Object],[object Object],[object Object]
Tools to overcome unstable VT Mapping activation with a single beat Non-contact mapping
Circulatory assistance ,[object Object],[object Object],[object Object],[object Object],Carbuccicchio et al. Circulation 2009
Carbuccicchio et al. Circulation 2009
Ablation of VPB’s ,[object Object],[object Object],[object Object],[object Object],Bogun et al Heart and Rhythm 2008
Relationship of frequent VPB’s to the reentry circuit of scar-related tachycardia Bogun et al. Heart and Rhythm 2008
Present Limitations of VT Ablation ,[object Object],[object Object],[object Object],[object Object],[object Object]
De Bakker et al. JACC 1990
Defining Channels of conduction within the scar during sinus rythm Arenal et al.Circulation 2004
Present Limitations of VT Ablation ,[object Object],[object Object],[object Object],[object Object],[object Object]
Epicardial Origin ,[object Object],[object Object],[object Object],Berruezo A, et al. Circulation 2004. Berrruezo et al Circulation 2004 EPI ENDO TAT 
ECG recognition of epicardial origin Berruezo et al. Circ 2004 Pseudo delta in V2 > 34ms Intrinsecoid deflection in V2 > 85 ms Epicardial  Endocardial
Contraste en saco Catéter ablación
RV EPI
RF on
Bogun et al JACC 2009
Bogun et al  JACC 2009
Cardiac Image by ce-CMR Value in identifying scar location Epicardial VT  in a patient with a noncompaction of the LV - Hyperenhancement (scar) - Abnormal electrograms
Codreanu et al JACC 2008
Khaykin  et al Heart and Rhythm 2008
Mapping inside the CS GCV-AIV CS RVd 33 msec
Endocardial lesions (RF and fulguration) Epicardial lesions
New energy sources and better image techniques ,[object Object],[object Object],[object Object]
Noninvasive Evaluation of RF Lesions in the Human Ventricular Myocardium by Ce-CMR ,[object Object],[object Object],[object Object],[object Object],Berruezo et al. Circ Arryth 2009
Noninvasive Evaluation of RF Lesions in the Human Ventricular Myocardium by Ce-CMR Berruezo A, et al. Circulation Arrhythmia 2009.
Berruezo et al. Circ Arryth 2009 B A C D
Cardiac Image by ce-CMR Value in identifying scar location Epicardial hyperenhancement Endocardial normal EGs Epicardial re-entrant VTs
Cardiac Image by ce-CMR Tissue characterization 50%
Cardiac Image by ce-CMR Tissue characterization 60%
Cardiac Image by ce-CMR Tissue characterization
What do we need to improve results ? ,[object Object],[object Object],[object Object],[object Object]
 

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Aspirin presentation slides by Dr. Rewas Ali
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Dr. J.L. Mont Girbau: ¿Cómo reducir las descargas en pacientes portadores de DAI?

Editor's Notes

  1. In 2004 we demonstrated that it is posible to identify the epicardial origin of the ventricular activation on the surface ECG. To demonstrate the hypothesis that epicardial pacing increases the initial duration of the QRS with respect to the endocardial pacing, we paced several patients from the epicardium and the endocardium of the LV free wall at a similar site When pacing was performed from the epicardium, as compared when the stimulus was delivered from the endocardium: 1) Although we obtained a similar QRS configuration 2) the presence of a pseudo delta wave increased the duration of the initial part of the QRS complex and 3) this pseudo delta wave matched with the transmural activation time.
  2. DURÁN PORRAS Ejemplo (Martí Recover): - Previous failed ablation - ECG - Mapa Endo - Resonancia - Finalmente mapa Epi