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CAR-T:
Market Perspectives
April 15, 2015
Brand Acumen
The Global Leader in Pharmaceutical Name Development
CAR-T: Market Positioning
2	
  
The purpose of this presentation is
to examine the CAR-T market
landscape with an eye on brand
positioning, market messaging and
current external perceptions.
The contents include a high level
overview of the nomenclature and
nascent brand architecture of the
primary companies, a review of the
evolving CAR-T lexicon, and the
results of a CAR-T specific Brand
Equity Perception Study conducted
in March, 2015.
Differentiation Dimensions
Overview:
The CAR-T
Nomenclature and
Nascent Brand
Architecture
Brand Acumen’s
CAR-T
Brand Equity
Perception Study
March, 2015
A Review of the
Evolving
CAR-T Lexicon
Celyad
Transposagen
Cellular Biomedicine
Carsgen
Unum
Caribou Biosciences
Xcyte
WuXi
Atara
CAR-T
émergent
nomenclature
corporatebrands
CAR-T
anewlexicon
chimeric antigen receptor therapy
SurveyDesign
5	
  
To initiate the CAR-T Brand Equity
Study we surveyed five segments
of Key Innovation Leaders (KILs).
•  Bio Industry Writers (8)
•  Venture Capitalists (7)
•  Oncologists (35)
•  CAR-T Specific Researchers (21)
•  Market Makers/Analysts (12)
CAR-TBrandEquityPerceptionStudy
Brand Acumen’s CAR-T Brand Equity survey methodology brings together market,
brand, competitive, and technological attribute perceptions.
A corporate brand’s performance can be assessed allowing for a roadmap for
improvement to be identified in micro-niche biotech ecosystems.
samplesize/
numberofrespondents
Each of the six attribute
categories are scored from
0-100 with 0 being the lowest
and 100 the highest score.
The scores are weighted
based on respondents
answers to quantitative and
qualitative criteria.
chimeric antigen receptor therapy
CAR-T:
The Main Players
A Review of Company Nomenclature and
Results of the Brand Acumen CAR-T Brand Equity Perception Study
7	
  
CAR-T
nomenclature
@NascentCAR-TNomenclature
tisagenlecleucel-T
Alternative Names:
•  Anti-CD19-CAR retroviral vector-transduced autologous T
cells - University of Pennsylvania
•  Anti-CD19-CAR transduced T cells - Novartis/University of
Pennsylvania
•  CART-019; CART-19; CART-19 cells
•  Chimeric antigen receptor-modified T cells against CD19 -
University of Pennsylvania/Novartis
•  CTL 019
•  LG-740
Most Recent Events
26 Feb 2015
Phase-II clinical trials in
Diffuse large B cell lymphoma
in USA (IV) (Novartis, pipeline,
February 2015)
08 Dec 2014 Efficacy data from
a pediatric study in Acute
lymphoblastic leukemia
presented at the 56th Annual
Meeting and Exposition of the
American Society of
Hematology (ASH-Hem-2014)
15 Oct 2014 Interim efficacy
and adverse events data from
two phase I trials in Acute
lymphoblastic leukemia
(second-line therapy or
greater) released by University
of Pennsylvania
tisa – gen – lec – leu – cel - T
generic name
•  MesoCART
•  huCART19
non-proprietary name
CRISPR/Cas9
CAR-TBrandEquityPerceptionStudy
Each of the six attribute categories are scored from 0-100 with 0 being
the lowest and 100 the highest score.
CAR-TBrandEquityPerceptionStudy
Each of the six
attribute
categories are
scored from 0-100
with 0 being the
lowest and 100 the
highest score.
The scores are
weighted based on
respondents
answers to
quantitative and
qualitative criteria.
CAR-T
nomenclature
@NascentCAR-TNomenclature
Sleeping Beauty
RheoSwitch®
platformbrands
AttSite®
UltraVector®
LEAP®
CAR-TBrandEquityPerceptionStudy
Each of the six attribute categories are scored from 0-100 with 0 being
the lowest and 100 the highest score.
CAR-TBrandEquityPerceptionStudy
Each of the six
attribute
categories are
scored from 0-100
with 0 being the
lowest and 100 the
highest score.
The scores are
weighted based on
respondents
answers to
quantitative and
qualitative criteria.
CAR-T
nomenclature
@NascentCAR-TNomenclature
Lentiglobin®
Lenti-D®
Starbeam Study
North Star Study
branded clinical studies
brands
CAR-TBrandEquityPerceptionStudy
CAR-TBrandEquityPerceptionStudy
Each of the six
attribute
categories are
scored from 0-100
with 0 being the
lowest and 100 the
highest score.
The scores are
weighted based on
respondents
answers to
quantitative and
qualitative criteria.
CAR-T
nomenclature
@NascentCAR-TNomenclature
eACT™
T-Cell Factory B.V.
acquisition
collaboration
platformbrand
CAR-TBrandEquityPerceptionStudy
Each of the six attribute categories are scored from 0-100 with 0 being
the lowest and 100 the highest score.
CAR-TBrandEquityPerceptionStudy
Each of the six
attribute
categories are
scored from 0-100
with 0 being the
lowest and 100 the
highest score.
The scores are
weighted based on
respondents
answers to
quantitative and
qualitative criteria.
CAR-T
nomenclature
@NascentCAR-TNomenclature
CaspaCIDe™
CIDeCAR™
GoCAR-T™
DeCIDe™
brands
CAR-TBrandEquityPerceptionStudy
Each of the six attribute categories are scored from 0-100 with 0 being
the lowest and 100 the highest score.
CAR-TBrandEquityPerceptionStudy
Each of the six
attribute
categories are
scored from 0-100
with 0 being the
lowest and 100 the
highest score.
The scores are
weighted based on
respondents
answers to
quantitative and
qualitative criteria.
CAR-T
nomenclature
@NascentCAR-TNomenclature
Armored CAR technology
technology brand
CAR-TBrandEquityPerceptionStudy
Each of the six attribute categories are scored from 0-100 with 0 being
the lowest and 100 the highest score.
CAR-TBrandEquityPerceptionStudy
Each of the six
attribute
categories are
scored from 0-100
with 0 being the
lowest and 100 the
highest score.
The scores are
weighted based on
respondents
answers to
quantitative and
qualitative criteria.
CAR-T
nomenclature
@NascentCAR-TNomenclature
pipeline identifier brand
UCART
CAR-TBrandEquityPerceptionStudy
Each of the six attribute categories are scored from 0-100 with 0 being
the lowest and 100 the highest score.
CAR-TBrandEquityPerceptionStudy
Each of the six
attribute
categories are
scored from 0-100
with 0 being the
lowest and 100 the
highest score.
The scores are
weighted based on
respondents
answers to
quantitative and
qualitative criteria.
evolutionary.
revolutionary.
disruptive.
28	
  
Brand Acumen
19 Leonard St.
NY, NY 10013
Bill Smith, CEO
(Call Bill. 704.906.3402)
william.smith@brandacumenstudios.com

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