A non-invasive maternal blood test that can detect certain fetal chromosomal disorders, including Down syndrome, early in pregnancy is improving some skill of attention as a potential new method of prenatal screening. Currently, several organizations support its use in pregnant women at high risk of having a child with a disorder caused by an abnormal number of chromosomes. However, invasive diagnostic tests, such as chorionic villus sampling (CVS) and amniocentesis, are needed to confirm the results, still.

1. Blood Test for Detecting Fetal
Abnormalities Gaining Interest

2. A non-invasive maternal blood test that can detect certain fetal
chromosomal disorders, including Down syndrome, early
in pregnancy is improving some skill of attention as a potential
new method of prenatal screening.
Currently, several organizations support its use in pregnant women
at high risk of having a child with a disorder caused by an
abnormal number of chromosomes.
However, invasive diagnostic tests, such as chorionic villus
sampling (CVS) and amniocentesis, are needed to confirm the
results, still.

3. cell-free fetal DNA (cffDNA)
The test, which was first introduced in October 2011, is called cell-
free fetal DNA (cffDNA) and requires only a blood draw from a
pregnant woman’s arm.
The blood sample is tested for fetal cell-free genetic material that
circulates in her blood.
Currently, the test screens for three genetic disorders: Down
syndrome, Edwards syndrome, and Patau syndrome.
It identifies approximately 85% of women carrying a fetus with
Down syndrome with a false positive rate of 5%.

4. About Trisomy disorders :
By comparison, studies of cffDNA have shown an ability to
recognize 98% of cases of Down syndrome, with a false positive
rate of less than 0.5%, even though these studies were surrounding
between high risk women only.
The first trimester screen only reviews the risk of Down syndrome
and Edwards syndrome, whereas cffDNA screens for three trisomy
disorders with the potential for high.

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