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What is the mechanistic basis for protein-protein interactions- Polype.pdf

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What is the mechanistic basis for protein-protein interactions? Polypeptides unfold into an energetically disfavorable conformation to facilitate the interaction. Peptide bonds between each amino acid are hydrolyzed to facilitate the interactions. Amino acid R-groups (side chains) interact with each other through hydrogen bonds, hydrophobic interactions, and ionic bonds. Each protein is incorporated into the other protein's secondary structure to facilitate the interaction..

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What is the mechanistic basis for protein-protein interactions? Polypeptides unfold into an energetically disfavorable conformation to facilitate the interaction. Peptide bonds between each amino acid are hydrolyzed to facilitate the interactions. Amino acid R-groups (side chains) interact with each other through hydrogen bonds, hydrophobic interactions, and ionic bonds. Each protein is incorporated into the other protein's secondary structure to facilitate the interaction.

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