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• An Obsolete past OR the Next big thing?
Making a case for Colpocleisis
Ajay Dhawle
12.09.2017
• “Simple, Effective & Underutilized”
History
• (Greek) Kolpos: folds; Cleisis: closure
• 1823 Gerardin described denuding the anterior and posterior
vaginal wall at the introitus and suturing them
• Current technique: A modification of that first described in
1877 by Leon LeFort.
• LeFort’s Repair: Partial colpocleisis technique that left the
uterus in situ, after which a perineorrhaphy was performed 8
days postoperatively.
• His technique was based on the premise that apposition of
the vaginal walls could prevent uterine prolapse and that a
widened genital hiatus may lead to unsuccessful outcomes.
What is colpocleisis?
Pre-requisites
• NOT sexually active
• Stage 3-4 prolapse
• ?Failed pessary/ not suitable
Advantages
• Fairly simple: LA/ regional
• Quick: shorter operating times
• Low morbidity, faster recovery
• Low recurrence rates
• Gentler learning curve (vs SSF/Sacro-
colpopexy)
Outcomes
• Zebede et al reported a 98.1% anatomic
success (310 women) with a 92.9% patient
satisfaction.
• The complication rate was low (15.2%) and
the mortality rate was 1.3%.
Concerns
• Regret
• Body image
• Access to cervix/ uterus
• Pyometra
• Pelvic abscess
• Worsening of UI
• Multicenter study by Crisp et al, colpocleisis as a definitive
surgical intervention resulted in a positive impact on bowel,
bladder, and prolapse symptoms. A high rate of satisfaction
and low levels of regret were reported.
• (Crisp CC, Book NM, Smith AL, Cunkelman JA, Mishan V, Treszezamsky AD, et al.
Body image, regret, and satisfaction following colpocleisis. Am J Obstet Gynecol.
2013 Nov. 209(5):473.e1-7.)
• Ninety five percent of those patients reported that they were
either “very satisfied” or “satisfied” with the outcome of their
surgery
• Fitzgerald MP, Richter HE, Bradley CS, Ye W, Visco AC, Cundiff GW, et al. Pelvic
support, pelvic symptoms, and patient satisfaction after colpocleisis. Int
Urogynecol J Pelvic Floor Dysfunct. 2008 Dec. 19(12):1603-9.
• De novo or worsening urinary incontinence is one of the
drawbacks of colpocleisis. However, the same risk is present in
approximately 40% of women who undergo surgical
reconstructive procedures for POP without a continence
operation
• Albo ME, Richter HE, Brubaker L, et al, for Urinary Incontinence Treatment Network. Burch
colposuspension versus fascial sling to reduce urinary stress incontinence. N Engl J Med.
2007;356:2143–2155.
Post Colpocleisis cancer
• Cervical smears/ biopsies
• PMB
R Elkattah, A Brooks, and R K Huffaker, “Gynecologic
Malignancies Post-LeFort Colpocleisis,” Case Reports
in Obstetrics and Gynecology, vol. 2014,
Alternatives
Anatomical repair
• Surgically complex
• Recurrence
• Steep learning curve
• Complications
Pessary
• Also not compatible
with sexual intercourse
• Need for follow up/
replacement
• PV discharge/ bleeding
• Erosion/ incarceration/
fistulae
• Palliative rather than
curative
• Economic viability esp
over long term?
Surgical Fitness?
Why Colpocleisis makes sense?
• Ageing population
• Increasing co-morbidities
• Obviates need for F/U
• Economically viable
• Low recurrence/ Good satisfaction rates
•Sexual activity: women ages 57 to 64 = 62%
women ages 75 to 85 =17%
•(Hullfish KL, Bovbjerg VE, Steers WD. Colpocleisis for pelvic organ prolapse:
patient goals, quality of life, and satisfaction. Obstet Gynecol. 2007 Aug. 110(2 Pt
1):341-5)
Unanswered Questions
• ? Concomittant incontinence procedures
• ? Safety as a day case
• ? Routine hysterectomy prior to Colpocleisis
• Eastern philosophy of ‘Karma’
• ‘What goes around, comes around’
Thank you

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Making a case for colpocleisis.ppt

  • 1. • An Obsolete past OR the Next big thing?
  • 2. Making a case for Colpocleisis Ajay Dhawle 12.09.2017
  • 3. • “Simple, Effective & Underutilized”
  • 4. History • (Greek) Kolpos: folds; Cleisis: closure • 1823 Gerardin described denuding the anterior and posterior vaginal wall at the introitus and suturing them • Current technique: A modification of that first described in 1877 by Leon LeFort. • LeFort’s Repair: Partial colpocleisis technique that left the uterus in situ, after which a perineorrhaphy was performed 8 days postoperatively. • His technique was based on the premise that apposition of the vaginal walls could prevent uterine prolapse and that a widened genital hiatus may lead to unsuccessful outcomes.
  • 6.
  • 7. Pre-requisites • NOT sexually active • Stage 3-4 prolapse • ?Failed pessary/ not suitable
  • 8. Advantages • Fairly simple: LA/ regional • Quick: shorter operating times • Low morbidity, faster recovery • Low recurrence rates • Gentler learning curve (vs SSF/Sacro- colpopexy)
  • 9. Outcomes • Zebede et al reported a 98.1% anatomic success (310 women) with a 92.9% patient satisfaction. • The complication rate was low (15.2%) and the mortality rate was 1.3%.
  • 10. Concerns • Regret • Body image • Access to cervix/ uterus • Pyometra • Pelvic abscess • Worsening of UI
  • 11. • Multicenter study by Crisp et al, colpocleisis as a definitive surgical intervention resulted in a positive impact on bowel, bladder, and prolapse symptoms. A high rate of satisfaction and low levels of regret were reported. • (Crisp CC, Book NM, Smith AL, Cunkelman JA, Mishan V, Treszezamsky AD, et al. Body image, regret, and satisfaction following colpocleisis. Am J Obstet Gynecol. 2013 Nov. 209(5):473.e1-7.) • Ninety five percent of those patients reported that they were either “very satisfied” or “satisfied” with the outcome of their surgery • Fitzgerald MP, Richter HE, Bradley CS, Ye W, Visco AC, Cundiff GW, et al. Pelvic support, pelvic symptoms, and patient satisfaction after colpocleisis. Int Urogynecol J Pelvic Floor Dysfunct. 2008 Dec. 19(12):1603-9.
  • 12. • De novo or worsening urinary incontinence is one of the drawbacks of colpocleisis. However, the same risk is present in approximately 40% of women who undergo surgical reconstructive procedures for POP without a continence operation • Albo ME, Richter HE, Brubaker L, et al, for Urinary Incontinence Treatment Network. Burch colposuspension versus fascial sling to reduce urinary stress incontinence. N Engl J Med. 2007;356:2143–2155.
  • 13. Post Colpocleisis cancer • Cervical smears/ biopsies • PMB R Elkattah, A Brooks, and R K Huffaker, “Gynecologic Malignancies Post-LeFort Colpocleisis,” Case Reports in Obstetrics and Gynecology, vol. 2014,
  • 14. Alternatives Anatomical repair • Surgically complex • Recurrence • Steep learning curve • Complications Pessary • Also not compatible with sexual intercourse • Need for follow up/ replacement • PV discharge/ bleeding • Erosion/ incarceration/ fistulae • Palliative rather than curative • Economic viability esp over long term? Surgical Fitness?
  • 15. Why Colpocleisis makes sense? • Ageing population • Increasing co-morbidities • Obviates need for F/U • Economically viable • Low recurrence/ Good satisfaction rates
  • 16. •Sexual activity: women ages 57 to 64 = 62% women ages 75 to 85 =17% •(Hullfish KL, Bovbjerg VE, Steers WD. Colpocleisis for pelvic organ prolapse: patient goals, quality of life, and satisfaction. Obstet Gynecol. 2007 Aug. 110(2 Pt 1):341-5)
  • 17. Unanswered Questions • ? Concomittant incontinence procedures • ? Safety as a day case • ? Routine hysterectomy prior to Colpocleisis
  • 18. • Eastern philosophy of ‘Karma’ • ‘What goes around, comes around’

Editor's Notes

  1. His technique was based on the premise that apposition of the vaginal walls could prevent uterine prolapse and that a widened genital hiatus may lead to unsuccessful outcomes. His theory holds true today; this obliterative procedure is associated with high rates of satisfaction.
  2. The LeFort method involves denudation and approximation of the midportions of the anterior and posterior vaginal walls.8 This operation creates a longitudinal vaginal septum with bilateral channels on each side, which serve as conduits for any secretion or bleeding from the apical vagina. Aggressive perineorraphy is also needed to shorten the genital hiatus. The following description incorporates perineorraphy into the LeFort technique.
  3. In a study of 310 women, the largest case series to date, Zebede et al reported a 98.1% anatomic success with a 92.9% patient satisfaction. The complication rate was low (15.2%) and the mortality rate was 1.3%; this suggests that colpocleisis is a low-risk, effective procedure.
  4. 5 endometrial 2 ovarian 1 Cx, 1 Vaginal Evaluating candidates for cervical or uterine abnormalities prior to surgery is therefore important. This entails reviewing previous pap smears and cervical biopsies and asking targeted questions regarding patients with postmenopausal bleeding who may require endometrial biopsy or ultrasound to evaluate endometrial thickness