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Hemorrhage:
*Definition: is the excess loss of blood due to rupture of blood vessels
*Types and causes of hemorrhage:
1-Accidental hemorrhage: occurs in road accidents and industrial accidents , accidental
hemorrhage is two type:
a-primary hemorrhage: which occurs immediately after the accident
b- secondary hemorrhage: which occurs about few hours after accident.
2-capillary hemorrhage :is bleeding due to the rupture of blood vessels particularly
capillaries , it is very common in brain (cerebral hemorrhage)
3-Internal hemorrhage: is the bleeding in viscera , it is caused by rupture of blood vessels
in the viscera , the blood accumulates in viscera
4-postpartum hemorrhage: excess bleeding that occurs immediately after labor
5-Hemorrhage due to premature detachment of placenta
*Compensatory effects of hemorrhage: different in acute or chronic
hemorrhage:
1-acute hemorrhage: is the sudden loss of large quantity of blood, it occurs in conditions
like accidents,โ†“ in blood volume โ†’hypovolemic shock
2-chronic hemorrhage: is the loss of blood either by internal or external bleeding over a
long period of time, internal bleeding occurs in condition like ulcer, external occurs in
condition like hemophilia
*Immediate compensatory effects of hemorrhage:
1-On cardiovascular system: reduced blood volume after hemorrhage โ†“ venous
return , ventricular filling and cardiac output, in severe hemorrhage , there is fall in blood
pressure also ,
#Mechanism involved in maintenance of blood pressure during mild
hemorrhage: when there is loss of a small amount of blood up 350 to 500 ml
1- Usually when arterial blood pressure increase โ†’ stimulation of carotid and
aortic baroreceptors โ†’send impulses to brain โ†’โ†“ in blood pressure , during
hemorrhage falls in arterial blood pressure , baroreceptors become in activated
and stop discharging impulses
2- This increase the vasomotor tone leading to vasoconstriction in all regions of
body except brain and heart
3- Vasoconstriction result in increase in peripheral resistance
4- Loss of blood causes reflex constriction of veins
5- Venoconstriction enhance the venous return , ventricular filling
6- Because of โ†‘peripheral resistance the arterial blood pressure is restored
7- One more factor is involved in this mechanism vasoconstriction occurs in organs
having reservoir function such as skin , liver , and spleen , blood from these
reservoir organs is directed in to systemic circulation , this my compensate the
volume of blood that is lost during hemorrhage.
*Mechanism involved in maintenance of blood pressure during sever
hemorrhage:
1-when hemorrhage is severe with loss of about 1,500 to 2,000 ml of blood
2-the arterial blood pressure falls to great extend, it is because venous return and stroke
volume
3-in the heart , the reflex tachycardia increase the quantity of metabolic products in
myocardium
4-these metabolic products causes coronary vasodilatation
2- on skin:

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Hemorrhage

  • 1. Hemorrhage: *Definition: is the excess loss of blood due to rupture of blood vessels *Types and causes of hemorrhage: 1-Accidental hemorrhage: occurs in road accidents and industrial accidents , accidental hemorrhage is two type: a-primary hemorrhage: which occurs immediately after the accident b- secondary hemorrhage: which occurs about few hours after accident. 2-capillary hemorrhage :is bleeding due to the rupture of blood vessels particularly capillaries , it is very common in brain (cerebral hemorrhage) 3-Internal hemorrhage: is the bleeding in viscera , it is caused by rupture of blood vessels in the viscera , the blood accumulates in viscera 4-postpartum hemorrhage: excess bleeding that occurs immediately after labor 5-Hemorrhage due to premature detachment of placenta *Compensatory effects of hemorrhage: different in acute or chronic hemorrhage: 1-acute hemorrhage: is the sudden loss of large quantity of blood, it occurs in conditions like accidents,โ†“ in blood volume โ†’hypovolemic shock 2-chronic hemorrhage: is the loss of blood either by internal or external bleeding over a long period of time, internal bleeding occurs in condition like ulcer, external occurs in condition like hemophilia *Immediate compensatory effects of hemorrhage: 1-On cardiovascular system: reduced blood volume after hemorrhage โ†“ venous return , ventricular filling and cardiac output, in severe hemorrhage , there is fall in blood pressure also , #Mechanism involved in maintenance of blood pressure during mild hemorrhage: when there is loss of a small amount of blood up 350 to 500 ml 1- Usually when arterial blood pressure increase โ†’ stimulation of carotid and aortic baroreceptors โ†’send impulses to brain โ†’โ†“ in blood pressure , during
  • 2. hemorrhage falls in arterial blood pressure , baroreceptors become in activated and stop discharging impulses 2- This increase the vasomotor tone leading to vasoconstriction in all regions of body except brain and heart 3- Vasoconstriction result in increase in peripheral resistance 4- Loss of blood causes reflex constriction of veins 5- Venoconstriction enhance the venous return , ventricular filling 6- Because of โ†‘peripheral resistance the arterial blood pressure is restored 7- One more factor is involved in this mechanism vasoconstriction occurs in organs having reservoir function such as skin , liver , and spleen , blood from these reservoir organs is directed in to systemic circulation , this my compensate the volume of blood that is lost during hemorrhage. *Mechanism involved in maintenance of blood pressure during sever hemorrhage: 1-when hemorrhage is severe with loss of about 1,500 to 2,000 ml of blood 2-the arterial blood pressure falls to great extend, it is because venous return and stroke volume 3-in the heart , the reflex tachycardia increase the quantity of metabolic products in myocardium 4-these metabolic products causes coronary vasodilatation 2- on skin: