SlideShare a Scribd company logo
1 of 19
Download to read offline
Varun Nemmani June 2016
University of Missouri- Kansas City
1
US Pharma Majors Go Shopping in India:
A Know-How Guide to Acquire & Invest in the Indian Pharmaceutical Industry
Abstract:
The present paper deals with the topic of the evolving landscape of the global pharmaceutical
industry, where the manufacturing and other vital operations do not take place any longer in the
conventional markets but have shifted to more cost-effective, emerging markets in the world. In
the wake of this transformation there has been a sudden rush in the industry to form global strategic
alliances/ partnerships and to acquire pharma companies. This trend of consolidation has caught
up with firms in both developed and emerging economies alike, to acquire the resources and
capabilities that would equip them with a sustainable competitive edge in a hyper-competitive
market. This research paper is an attempt at understanding- the forces that have caused the shift,
why the time is ripe for pharmaceutical firms in the US to expand beyond their comfort zone and
enter the race to expand into emerging markets- especially into India, the best route to enter the
Indian industry (investments and acquisitions), whom and how to select for mergers &
acquisitions, understanding the various opportunities and issues of operating in the Indian market,
the various elements that make up the Indian industry and the various factors at play there, which
make it unique in ways more than one, strategies to capture the Indian market and how to transform
the organizational culture, manufacturing practices and supply chain to make the acquisition not
only a success story but also to ensure the company abides by the rules and regulations of the
USFDA. Last but not the least, the paper would also examine the exit strategies, in case the
acquisition doesn’t turn out quite right.
Varun Nemmani June 2016
University of Missouri- Kansas City
2
Introduction:
The latest trend in the global pharmaceutical industry is of mergers, acquisitions, alliances and
partnerships to cooperate with each other. The major reasons behind such a move of consolidation
in the industry is that Research & Development costs are spiraling up, developing drugs is time
consuming, the development phase can be stuck in the pipeline for years together, results are highly
uncertain and drugs can often fail at the clinical trial phase as well, the possibility of finding the
‘blockbuster’ drug is quite rare and more often than not access to international markets if often
draught with various regulatory issues as well as severe competition. Not all companies have the
necessary funds, skills and capabilities to achieve the desired level of innovation and
manufacturing capacities. When a drug is in the pipeline, with a lot of investment locked in,
sustainability can become an issue. The desperation to survive and to continue earning revenues
to keep the firm running against all odds, often makes these businesses turn a blind eye to quality
and regulatory issues. This is when a pharmaceutical company earns the risk of facing the wrath
of regulatory bodies such as USFDA, which can often lead to their drugs being banned from the
market. Hence a lot of pharma companies in the world are seeking M&A’s and alliances on a
global scale. The phenomenon of ‘consolidation’ in the pharma industry is a reality, it is here to
stay and is inevitable. This would enable them to not only acquire knowledge and gain skilled
workforce in the emerging economies but also leverage the low cost structure of the developing
markets. These international alliances would help a multinational company transform into a
transnational organization (Anonymous, 2006).
At this point, the question that begs to be asked is, why are American firms shifting their operations
and manufacturing base from their home turf to emerging markets like India? The answer is that-
i) revenues of US based companies are decreasing because of fall in prices of generic drugs, ii)
more generic drugs are being introduced into the market, iii) most of which are being pumped from
low-cost markets in to the US market, iv) M&A’s and global alliances are reducing the number of
firms manufacturing in the United States and v) the most important and perhaps an obvious reason
behind all this is the rising costs of manufacturing costs in the US (Greene, 2007).
There has been surging interest in the field of generics for a lot of reasons for quite some time now.
According to the reports of the US Trade Commission, of the 10 largest generic firms in the world,
9 belong to the US and these firms are out to capture generic drug manufacturers in low-cost
Varun Nemmani June 2016
University of Missouri- Kansas City
3
markets like that of India. Indian pharma companies have specialized the manufacture of generics
long before it became a hot topic of the global pharma industry. Another point of interest is the
cost of generics. They cost anywhere between 30-80% cheaper than the branded drugs and as a
result, close to 56% of the drugs prescribed by doctors in the US are generics and sales of generics
grew by 21% between the years 2004 and 2005 (Greene, 2007). Pharmaceutical companies
specializing in innovation too have diverted their attention towards generics now as their patented
drugs are about to lose their protection (patent expiry). For example, Pfizer, which had exited the
generics business long ago, re-entered the field of generics with the creation of ‘Established
Products’ in 2008 for manufacturing generics and later in 2009 and 2010 Pfizer had signed
contracts with two Indian firms for the manufacture and supply of vaccines and anti- cancer drugs
(Harding, 2010).
Now, let’s dissect the Indian pharmaceutical industry to understand the sudden interest it has been
garnering from its international counterparts.
The Indian Pharmaceutical Industry:
The Indian pharma industry is the third largest in the world in terms of the volume of exports and
ranks thirteenth in terms of value of its exports (India Brand Equity Foundation, 2016). The size
of the Indian pharma industry is estimated to be around $ 20 billion (Indiatimes, 2016) and the
export turnover of the industry is over $ 10 billion and it exports to more than 200 countries
(Taylor, 2014). The CAGR of the industry is 14%, whereas the growth rates of the pharma
industries in EU and US hover between 1-6% (Sharma, 2010). Up to 40% of the generic drugs
available in the US market come from India (Taylor, 2014) and as of 2014, the total value of the
exports to the US stands at $ 3.45 billion. Around 520 Indian firms are registered with USFDA
(Business line, 2015).
SWOT analysis of the industry:
Strengths of the Indian Pharmaceutical Industry:
 The biggest strength is perhaps its cost effectiveness and its capability to produce drugs at
the cheapest rate possible. According to the estimates of the US Trade Commission, the
labor costs are 50-55% cheaper in India than they are in the US, infrastructure costs are
40% cheaper, the fixed costs in the Indian pharma industry are less by 12-20%, cost of
Varun Nemmani June 2016
University of Missouri- Kansas City
4
developing bulk drugs is 60% less in India and the construction of a production plant costs
40% less.
 Most Indian pharma companies have immense experience in the field of reverse
engineering of drugs, which is a huge asset when it comes to the manufacture of generics.
 The industry specializes in ‘contract manufacturing’.
 India boasts of a large pool of English speaking, technically skilled workers who come at
a low cost.
 Rapidly developing and evolving infrastructure.
 Reformations in Patent laws to the advantage of firms looking to manufacture new drugs
(Greene, 2007).
Weaknesses of the Indian Pharmaceutical Industry:
 Huge investment gap in R&D and other innovation projects. As a result, it lags behind in
innovation and is hugely restricted to replicating existing drugs whose patents have expired
(Business line, 2016).
 The pharma industry and its supply chain are both highly fragmented.
 The Indian government imposes ‘price ceilings’ on certain important and lifesaving drugs
 The ever increasing problem of counterfeit drugs in the market.
 Absence of strong and established logistics players in the industry, as a result of which the
cost of distribution is high (Greene, 2007). Close to half of the costs in the supply chain
arise from logistics alone (Shetty, 2015).
 Lack of proper clinical trials.
 Lack of documentation of the processes involved.
 Insufficient information and compensation to patients participating in the clinical trials
(Taylor, 2014).
Opportunities in the Indian Pharmaceutical Industry:
 The fact that the Indian industry already boasts of such impressive exports and that the
exports are poised to touch the $ 50 billion mark by 2020 speaks volumes of the immense
opportunities that the Indian industry holds.
 Evolving and ever increasing demand in the Indian domestic market.
Varun Nemmani June 2016
University of Missouri- Kansas City
5
 $ 40 billion worth patented drugs have gone off patent in the year 2010 and many more
drugs will follow suit. Yet again this presents an opportunity to the companies to
manufacture generic drugs.
 The capital requirements to start operations in India are very low.
 The barriers of entry are low as well (Taylor, 2014).
 The government provides tax benefits for companies investing in the Indian industry.
 Changing patent laws.
 Reduction of custom duties.
 India has a huge untapped market for drugs.
 Huge and diverse population makes India an ideal location for conducting clinical trials
and R&D experiments (Shetty, 2015).
Threats facing the industry:
 In the year 2014, nineteen warning letters were issued by the USFDA, of which eight were
issued to Indian pharma companies according to a survey by Ernst and Young (Business
line, 2015).
 Not all firms have USFDA approvable facilities (Harding, 2010).
 Shortage of funds, staff and mounting work pressure on the existing staff leading to false
and inaccurate documentation and manufacturing practices (Business line, 2015).
 Expanding interest of the pharma companies towards other low-cost emerging markets
such as Mexico, Brazil, Chile, Romania, South Africa, Singapore, South Korea and
Australia (Harding, 2010).
 Increasing competition from China, which is able to manufacture intermediates and bulk
drugs at a much cheaper rate and a lot faster too. The dumping of Chinese drugs in the
Indian market has led to the closure of some Indian businesses as well.
 Lax policies and lack of sufficient regulatory procedures to look into the irregularities of
the pharmaceutical industry (Lalitha, 2002).
The weaknesses, threats and other challenges of the Indian pharma industry are certainly
outweighed by its strengths and opportunities. For these very reasons the global pharma majors
can’t ignore the unique opportunities India bestows upon those who would want to invest in it
Varun Nemmani June 2016
University of Missouri- Kansas City
6
(Shetty, 2015). It is estimated that these international players will eventually capture 60% of the
Indian pharma industry in the near future and these M&A’s will infuse cash and inject innovation
into the industry (Business line, 2016), i.e., will only enable the Indian firms to invest more in their
R&D programs, to move up the value chain and diversify their product portfolio (Greene, 2007).
Why is it so crucial for the Indian pharma industry to attract foreign investments?
We have already seen that most of the Indian firms are strapped for cash and hence aren’t able to
move up the ladder of innovation or stick to the GMP guidelines laid down by the USFDA. It isn’t
just a random observation that investments into manufacturing facilities and innovation projects
are highly correlated to the export performance of a firm. It has been validated by a study
conducted by Rentala and Anand in 2014 on 142 Indian pharma companies using the OLS and
Quantile Regression methods. The analysis revealed positive correlation between- efforts/
investments put into R&D projects, age of the firm, monetary compensation given to employees,
fixed assets of the firm, import of capital goods/ raw materials and exports of the firm. Higher the
efforts, larger the investment into innovation programs and GMP higher the value/ volume of
exports (Rentala & Anand, 2014).
Impact of competition on R&D in the Indian pharma industry:
Let us try and understand the impact of competition within the industry on the R&D expenditure
of a firm.
A study has found that there is an Inverted-U relationship between amount of investment/intensity
of R&D efforts and market concentration in the Indian pharma industry. Essentially this means
that pharma companies try to spend a lot on R&D even when their market share is low, which in
turn reflects the magnitude of competition in the industry. As the market share and profit margins
of a firm go up, so does its spending on R&D. This has led to the Indian firms clamor for
collaboration and alliances in the field of R&D, primarily to decrease their cost of innovation and
lower their risk associated with the development of new drugs (Das & Das, 2015).
Mode of entry into the Indian pharma industry:
Having understood the various facets of the industry and the various forces at play, let’s examine
the best ways to enter it.
Varun Nemmani June 2016
University of Missouri- Kansas City
7
The Government of India allows 100% Foreign Direct Investment in greenfield pharmaceuticals
(a greenfield investment is one when a MNC invests in another country to start a new
manufacturing facility) and 74% FDI through the brownfield mode of investment (a type of
investment where a MNC purchases existing plant or facilities to start operations in a foreign
country). Considering the present market circumstances (stringent requirements of the USFDA,
market dynamics in the US and India and the needs of Indian companies) it is advisable that US
firms enter the Indian market through the brownfield mode of investment. In fact, over 96% of the
FDI in the pharma sector flowed in through brownfield investments (Indiatimes, 2016).
That was the macro-economic picture of the mode of entry. Now, let’s look at the micro-economic
picture to examine the various models of business that a US firm can choose from depending on
its requirements.
Figure 1: The various business models that global pharma players can consider before entering
the Indian market.
Various companies from the US have already entered the Indian industry using one of the models,
depending on their needs (Shetty, 2015).
a) Outsourcing: Perhaps this is one of the oldest business models now and is quite safe and
risk free. Also, doesn’t entail a lot of investment. A lot of US companies have tried this
model before and continue to do so.
Ex: GVK Bio takes up contract research for US and European firms.
Business
Models
outsourcing
Varun Nemmani June 2016
University of Missouri- Kansas City
8
b) Licensing agreements: In this model, the firm that innovates the drug issues licenses to
firms in other countries either to manufacture or market them. This way the costs of
manufacturing and commercializing/marketing the drugs aren’t borne by the innovator
firm any longer, but they continue to yield profits through retained ownership and royalty
on licensing agreements.
c) Franchising: This mode of entry is more common in the retailing format of the pharma
industry. Government of India allows companies to start their own retail pharmacy stores
and franchise them to interested parties or partner with existing retail players.
Ex: Medicine Shoppe International, a US based firm, has already entered the retail industry
with numerous stores all over urban India. Fortis Healthcare too has made its entry into the
Indian market with about 1000 stores by 2012.
d) Joint Ventures: A more common option for firms looking to partner with local businesses
to gain advantage of their experience and knowledge of the local business environment.
Ex: India based CPL Biologicals will develop drugs for Cadila Pharmaceuticals and
Novavax using their proprietary formulae and technology.
e) Partially or Wholly owned subsidiaries: Pfizer has a stake of 72% in its India subsidiary
and Novartis fully owns two subsidiaries in India, which go by the names- Novartis
Consumer Health Private limited and Sandoz India Private Limited.
The advantage of a wholly owned subsidiary is that there’s very little risk of losing critical
information about technology and operation processes and they often get some tax
advantages well (Shetty, 2015).
Strategies to capture the Indian pharmaceutical market:
No merger or acquisition can be successful or complete without the knowledge of capturing the
domestic market. India’s domestic consumption of medicines is rising with changing
demographics and lifestyles and this translates into a huge market/ opportunity for American firms
looking to expand into India. More often than not the MNC’s might not have to look much beyond
the Indian market frontiers for their sales and revenues in the future (Shetty, 2015).
An article by McKinsey had analyzed the Brazilian pharma industry and had formulated various
strategies to capture the same. In ways more than one, India and Brazil share a lot of similarities.
Their economies are at a similar juncture and they face similar challenges and opportunities in
Varun Nemmani June 2016
University of Missouri- Kansas City
9
growth. The industries in both the economies are currently following a similar growth trajectory
and that is the reason why the strategies formulated to capture the Brazilian pharma market are
applicable to the Indian scenario as well.
In order to capture the market and devise strategies accordingly, one needs to classify and view
the pharma market as being made of three different sub-entities- Retail pharma market,
Institutional Public market and Institutional Private market. Let us now analyze the key drivers of
each segment and the strategies to capture them (Afonso, Dreszer, Francis, & Ramos, 2015).
Figure 2: Illustration of the three classifications or sub-entities in the pharmaceutical market
A. Retail Market:
 Key Drivers of this segment- The average disposable income per person is rising, the
population is growing, trade discounts and penetration of generics.
 Strategies to capture this segment- Establish relationship/ partnership with local
companies, suppliers, distributors, wholesalers and retailers, ensure supply of low cost
drugs as India is a cost conscious and cost sensitive market, reach out to consumers in mid-
sized cities (as this is where most of the growth would be in the future), also this would
require the MNC’s to create new capabilities and supply chain maps to penetrate the market
better, identify segments of population that would most probably use medicines and target
them accordingly and develop ‘customer centric supply chains’ by going beyond the sales
of medicines by tracking and monitoring the health of their consumers, develop awareness
programs about diseases & how to manage them better and supply of health monitoring
Pharmaceutical
Market
Retail Market
Institutional
Public Market
Insitutional
Private Market
Varun Nemmani June 2016
University of Missouri- Kansas City
10
devices- these strategies would not only help increase sales but also give a fillip to the
image of the pharma company (Afonso et al., 2015).
B. Institutional Public Market:
 Key drivers of this segment- GDP growth and increased government spending on health as
a percentage of GDP (Worldbank, 2015). The federal government has asked the states to
increase their funding on health (Kalra, 2015). Proactive policies to attract more FDI into
this sector, relaxation of licensing policies and quicker approvals to start the manufacturing
operations. Also, the new patent laws are attracting more foreign investment (Invest India,
2012).
 Strategies to capture this segment- the MNC’s need to understand how public hospitals
work and how the doctors there prescribe medicines to their patients, develop resources
and capabilities to strike a relation with these institutions/ doctors for a more direct
approach to reduce barriers/ middlemen, this will lead to increased prescriptions and sales,
it is better not to deal with middle men working for the public hospitals or local/federal
governments (Afonso et al., 2015).
C. Institutional Private Market:
 Key drivers of this segment- increasing expenses on hospitalization and therapies.
 Strategies to capture this segment- MNC’s should invest time and resources to better the
individual consumer, private hospitals and also the health insurance providers. Should
understand the needs and behavior of consumers and also what drives the doctors to
prescribe certain drugs. The focus of the MNC should be towards understanding and
dealing with clinical operations and nursing departments in private hospitals and pharmacy
stores as well. Dealing with health insurance providers would give the firms a competitive
edge, enabling them to penetrate the market better (Afonso et al., 2015).
Major acquisitions in the Indian Pharma sector:
The story of M&A’s with Indian companies is not a new one. In fact, it has been happening at a
very fast rate over the last four years. Here’s the list of some of the most famous acquisitions in
the Indian industry-
Varun Nemmani June 2016
University of Missouri- Kansas City
11
1. Mylan Labs of US had bought 71.5% equity in Matrix Labs of India
2. A German health care group had acquired 73.3% stake in Dabur Pharma
3. Ranbaxy was bought by Japan based Daiichi Sankyo
4. French Pharma company- Sanofi Pasteur had bought Shanta Biotechnics (Sharma, 2010).
5. Chinese firm Fosun had recently acquired 86% stake in Gland Pharma (Economic times,
2016).
But, not all acquisitions have a happy ending, resulting in profits. Some acquisitions in the Indian
pharma industry had to be terminated half way through for a plenty of reasons. Let’s look at two
such stories to see what went wrong with the acquisition, how to avert those mistakes while
acquiring an Indian firm and other critical lessons to be learnt from their experiences, as Otto von
Bismarck once said “the wise man learns from the mistakes of others”.
I) Daiichi Sankyo sells Ranbaxy:
The story of Daiichi Sankyo’s acquisition of Ranbaxy is one of a failure. When the Japanese firm
bought Ranbaxy five years ago, it expected the acquisition to fetch them billions of dollars in
return, but instead it cost them billions. The reason behind this is the USFDA decision of blocking
Ranbaxy’s products. The reasons behind the ban were shocking to say the least- the drugs were
adulterated, their labs lacked some critical amenities, dysfunctional doors and windows,
unhygienic conditions in the lab, small shards of glass inside pills. The workers in Ranbaxy’s
plants had no training whatsoever and were instructed to keep the production running with
continuous cuts in funding, over dependence on temporary workers, lack of inspections and false/
inaccurate test results (McLain, 2014).
Daiichi Sankyo found that the various departments in Ranbaxy were functioning in ‘silos’ and as
a result there was no flow of information or communication between departments and lack of
documentation of the processes in the company. Though the Japanese firm had tried to bring about
some transformation in the culture of the organization, they had to sell the organization, as every
passing day with Ranbaxy only meant mounting losses for Daiichi Sankyo. To curtail their losses
further, Daiichi Sankyo sells Ranbaxy to Sun Pharmaceuticals, the largest manufacturer of drugs
and vaccines in India (Mitra, 2013).
Varun Nemmani June 2016
University of Missouri- Kansas City
12
But, even Sun Pharma isn’t immune from the warning letters of USFDA. Sterility in their
manufacturing plants was a thing of concern for FDA officials. Today, Sun Pharma is actively
seeking large foreign investments in the fields of employee training, process automation, quality
control mechanisms and clinical trials (Kazmin, 2015).
II) Germany’s Fresenius Kabi gets FDA warning:
The German company had acquired 73% stake in India’s Dabur Pharma way back in 2008
(Economic times, 2008). They had to recall their cancer treatment drugs being shipped to the US
after discovering cross-contamination of drugs. This led to the firm losing some share in the
market, which analysts say will take time to recover and had a moderate impact on their finances
and share prices. Perhaps the biggest impact was that they halt their production, although it was
just temporary (Singh, 2010).
The problem was that the quality control staff and other management officials had manipulated
and hid QC data which led to a series of problems for the firm (Stanton, 2014).
Lessons to be learnt from these debacles:
Daiichi Sankyo’s former head of pharma research, Hidemi Minami has some excellent advice-
there should be seamless flow of information between the manufacturing, R&D and marketing
departments and must have mutual consensus throughout the process including the product launch.
The various jobs in the organization need to be stitched together for a product profile that’s ideal
for the market. There should be ample emphasis on teamwork and transparency at the workplace.
Formation of cross-functional teams to enable flexibility in the organization. There should be
synergy and consensus between the top management and employees of the organization. Indian
companies usually have the ‘top-down’ approach in management and MNC’s expanding into India
should strike a balance between the top-down and consensus approaches (Mitra, 2013).
For a problem like the once faced by the German firm Fresenius Kabi, MNC’s could adopt the
following strategies to avert those problems- there should be a third party audit of the firm to be
acquired and should seek a detailed report of the operating and manufacturing practices of the firm,
check if the firm already adheres to GMP’s, assess the management structure and organizational
culture and check if they are compatible; random and regular third party inspections of the
manufacturing site after the acquisition and have the reports sent to the headquarters, have a single,
Varun Nemmani June 2016
University of Missouri- Kansas City
13
cohesive work culture throughout the organization to ensure uniform implementation of best
practices and to stick to USFDA regulations; have regular training programs for employees on
GMP’s; more importantly, be prepared for eventualities such as the one faced by the German firm
and have a Business Continuity Plan, so that there is swift damage control to avoid huge
disruptions to the business operations; Data Integrity Assessments should be carried out in regular
intervals to inspect the level of compliance with USFDA and GMP’s (Business line, 2015).
India’s pharma supply chain and how to re-design it:
The pharma supply chain in India is highly fragmented and so is the distribution network, leading
to heavy dependence on retailers in the chain. The retailers are having to stock more inventory
than required (Supplychainbrain, 2013). The role of third party logistics providers is growing in
India. Though there are international logistics providers like UPS and FedEx in India, their
presence is limited only to large Indian cities. MNC’s have to depend on local logistics providers,
who have good idea of the market landscape and also provide comprehensive services (Ups, 2003).
According to Price Waterhouse Coopers, 45-55% of the costs in the supply chain stem from
logistics alone (Shetty, 2015). Though the adoption of latest technology was painstakingly slow in
the supply chain, of late, the integration of supply chain management software is picking up
quickly. MNC’s can meet the challenges posed by the Indian supply chain provided they keep in
mind that IT can be the prime enabler of the supply chain (Supplychainbrain, 2013).
Varun Nemmani June 2016
University of Missouri- Kansas City
14
Figure 3: Indian Pharmaceutical Supply Chain (Image Source:
http://www.biopharminternational.com/pharmaceutical-distribution-india )
Re-designing the supply chain:
i) Designing rapid distribution channels- to meet market demands on time, to reach it
with maximum efficiency and to keep the distribution costs low, MNC’s need to design
distribution networks that are speedy and agile.
ii) The supply chain should be capable of handling large consignments and be able to ship
them to international destinations precisely.
API & Raw materials supplier
Manufacturer
Carrying & Forwarding Agents
Distribution centre
Super stockists
Stockists Sub-stockists Hospitals
Pharmacy Retail store
consumer
Varun Nemmani June 2016
University of Missouri- Kansas City
15
iii) The firm should have control on the supply chain activities and should strive to improve
transparency in the supply chain (end-to-end visibility) (Ups, 2003).
iv) To introduce and implement the concept of ‘product pedigrees’ in the supply chain to
make sure the pharma products are safe and viable by the time they reach the
consumers. Pedigrees enable the companies to track the products anywhere in the
supply chain, thereby promoting integrity of the supply chain. This will also ensure that
counterfeit drugs do not enter the supply chain at any stage. An e-pedigree provides
information about the drug electronically. Data about the origin of the drug, date of
manufacture, expiry date, trade information of the drug all along the supply chain and
the names and addresses of all the players involved in the supply chain, is revealed. it
has been made mandatory by the USFDA (HIDA, 2013).
v) The onus is on the manufacturer to ensure communication and collaboration between
all the players in the supply chain. This would decrease the possibility of stock-outs.
vi) Forecasting and planning should become a part of the supply chain activities to
overcome the bull-whip effect.
vii) Data and feedback should be collected from all points in the supply chain in real time
(Handfield, 2005).
Conclusion:
The US firms wanting to expand into India should learn to play in a market that is not only
fragmented but also dominated by a lot of small scale businesses that are unregulated. Also, they
should learn to operate in a market where there is price ceiling imposed by the government.
Despite all the challenges in the Indian pharma industry or the market, the opportunities are too
good to resist. With many tax benefits, reduction of customs duties, improving infrastructure,
strong support of the government and more importantly changing patent laws, the scenario of the
industry seems to be brimming with positivity. All future estimates of the industry point at high
growth rates and industry leaders have termed it as the future leader of the global pharma industry.
There are plenty of options and companies to choose from. There are various modes of entry into
the industry. The growing consumption and demand for medicines in the Indian domestic market
promises a huge potential for MNC’s. The English speaking, technically skilled and low-cost
workforce make India a particularly attractive destination.
Varun Nemmani June 2016
University of Missouri- Kansas City
16
There are a lot of Indian companies facing fund crunch, stuck in huge debts, looking for expansion
and modernization of their facilities and seeking to invest further in their R&D projects.
Irrespective of their market size, almost all of them are seeking foreign investments in some form
or the other. This in itself presents an attractive opportunity for the US pharma majors to either
acquire them or strike some form of alliance with them. Many global pharma majors have realized
the potential and have staked their claim of the Indian pharma pie. All in all, the future of the
Indian pharma industry seems very optimistic and investment with caution would reap huge
benefits.
Varun Nemmani June 2016
University of Missouri- Kansas City
17
References:
1. Afonso, P., Dreszer, J., Francis, T., & Ramos, P. (2015). McKinsey. Retrieved 15 July,
2016, from http://www.mckinsey.com/industries/pharmaceuticals-and-medical-
products/our-insights/maintaining-momentum-in-brazils-pharmaceutical-market
2. Anonymous. (2006). Pharma's Global Karma. Strategic Direction, 22(1), 5-
8. Retrieved 15 July, 2016, from doi.org/10.1108/02580540610635852
3. Business line. (2016, 6th May). The Hindu Business Line: Injecting innovation into
Indian pharma. [Weblog]. Retrieved 15 July 2016, from
http://search.proquest.com.proxy.library.umkc.edu/docview/1787188840?pq-
origsite=summon
4. Business line. (2015, 5th June). The Hindu Business Line: Image of Indian pharma
industry tarnished: EY. [Weblog]. Retrieved 15 July 2016, from
http://search.proquest.com.proxy.library.umkc.edu/docview/1686129198?pq-
origsite=summon&accountid=14589
5. Das, P & Das, S. (2015). Competitiveness and its impact on research and development in
Indian pharmaceutical industry. Decision, 42(3), 325-334. Retrieved 18 July, 2016, from
http://dx.doi.org/ 10.1007/s40622-015-0099-8
6. Economic times. (2016). The Economic Times. Retrieved 18 July, 2016, from
http://economictimes.indiatimes.com/industry/healthcare/biotech/pharmaceuticals/chinas-
shanghai-fosun-to-acquire-86-stake-in-gland-pharma-for-1-4-
billion/articleshow/53423688.cms
7. Economic times. (2008). Economic Times. Retrieved 15 July, 2016, from
http://articles.economictimes.indiatimes.com/2008-04-20/news/27709803_1_dabur-
pharma-fresenius-se-fresenius-kabi-pte
8. Greene, W. (2007). US International Trade Commission. Retrieved 20 July, 2016, from
https://www.usitc.gov/publications/332/EC200705A.pdf
9. Handfield, R. (2005). Supply Chain Resource Consortium. Retrieved 15 July, 2016, from
http://www.supplychainredesign.com/publications/trends-pharma-biotech.pdf
10. Harding, D. (2010). Thomson Reuters. Retrieved 11 July, 2016, from
http://thomsonreuters.com/content/dam/openweb/documents/pdf/pharma-life-
sciences/white-paper/newport-deals.pdf
Varun Nemmani June 2016
University of Missouri- Kansas City
18
11. HIDA. (2013). Hida. Retrieved 16 July, 2016, from
http://www.hida.org/DEV/Government_Affairs/Industry_Issues/Pedigree_Supply_Chain
_Integrity_/HIDA2012/HIDA/Navigation/GovernmentAffairs/IndustryIssues/PedigreeSu
pplyChainIntegrity/Pedigree.aspx
12. India Brand Equity Foundation. (2016). IBEF. Retrieved 3 July, 2016, from
http://www.ibef.org/industry/pharmaceutical-india.aspx
13. Indiatimes. (2016). The Times of India. Retrieved 13 July, 2016, from
http://timesofindia.indiatimes.com/city/delhi/pharma-sector-to-grow-by-20-on-relaxed-
fdi-norms-govt/articleshow/52898987.cms
14. Invest India. (2012). InvestIndia. Retrieved 17 July, 2016, from
http://www.investindia.gov.in/pharmaceuticals-sector/
15. Kalra, A. (2015). Reuters. Retrieved 10 July, 2016, from
http://www.reuters.com/article/india-health-budget-idUSL4N0W20CA20150228
16. Kazmin, A. (2015). Financial Times. Retrieved 13 July, 2016, from
http://www.ft.com/cms/s/0/e03b0f96-a638-11e5-9700-2b669a5aeb83.html
17. Kelkar, A. (2008). Bio Pharm International. Retrieved 13 July, 2016, from
http://www.biopharminternational.com/pharmaceutical-distribution-india
18. Lalitha, N. (2002). Indian Pharmaceutical Industry in WTO Regime: A SWOT
Analysis. Economic and Political Weekly, 37(34), 3542-3555. Retrieved 19 July,
2016, from
http://www.jstor.org.proxy.library.umkc.edu/stable/pdf/4412521.pdf?_=1470123855588
19. McLain, S. (2014). WSJ. Retrieved 13 July, 2016, from
http://www.wsj.com/articles/SB10001424052702303456104579487381613887674
20. Mitra, M. (2013). Economic Times. Retrieved 14 July, 2016, from
http://articles.economictimes.indiatimes.com/2013-03-04/news/37437466_1_daiichi-
sankyo-ranbaxy-parvinder-singh
21. Rentala, S & Anand, B. (2014). Innovation Efforts and Export Performance of Indian
Pharmaceutical Industry: Empirical Evidence using Quantile Regression Approach. Bi-
annual Journal of Asian School of Business Management, 7(2), 10-20. Retrieved 17 July,
2016, from
Varun Nemmani June 2016
University of Missouri- Kansas City
19
https://ill.library.umkc.edu/illiad/illiad.dll?Action%3D10&Form%3D75&Value%3D335
072
22. Sharma, E. (2010). Business Today. Retrieved 3 July, 2016, from
http://search.proquest.com.proxy.library.umkc.edu/docview/507914912?pq-
origsite=summon&accountid=14589
23. Shetty, S. (2015). Pwc. Retrieved 113 July, 2016, from
http://www.pwc.com/gx/en/pharma-life-sciences/pdf/global-pharma-looks-to-india.pdf
24. Singh, K. (2010). Economic Times. Retrieved 13 July, 2016, from
http://articles.economictimes.indiatimes.com/2010-10-04/news/27614097_1_drugmaker-
cancer-drug-drug-regulator
25. Stanton, D. (2014). In-Pharma Technologist. Retrieved 14 July, 2016, from
http://www.in-pharmatechnologist.com/Processing/Fresenius-US-supply-from-troubled-
Indian-plant-to-restart-in-
Q3?utm_source=copyright&utm_medium=OnSite&utm_campaign=copyright
26. Supplychainbrain. (2013). Supplychainbrain. Retrieved 14 July, 2016, from
http://www.supplychainbrain.com/content/world-regions/asia-pacific/single-article-
page/article/indias-supply-chain-is-improving-but-still-has-a-long-way-to-go/
27. Taylor, K. (2014, 20th January). Challenges facing India's pharmaceutical
industry. [Weblog]. Retrieved 12 July 2016, from
http://blogs.deloitte.co.uk/health/2014/01/challenges-facing-indias-pharmaceutical-
industry.html
28. Ups. (2003). Ups. Retrieved 16 July, 2016, from https://www.ups-
scs.com/solutions/white_papers/wp_outsource_biotech.pdf
29. Worldbank. (2015). Worldbank. Retrieved 11 July, 2016, from
http://data.worldbank.org/indicator/SH.XPD.PUBL.ZS

More Related Content

What's hot

Global generic pharmaceuticals market – brighter times ahead
Global generic pharmaceuticals market – brighter times aheadGlobal generic pharmaceuticals market – brighter times ahead
Global generic pharmaceuticals market – brighter times aheadAiswariya Chidambaram
 
PROBLEMS AND PROSPECTS PHARMA PRODUCT SELLING..
PROBLEMS AND PROSPECTS PHARMA PRODUCT SELLING..PROBLEMS AND PROSPECTS PHARMA PRODUCT SELLING..
PROBLEMS AND PROSPECTS PHARMA PRODUCT SELLING..Subrata Ghosh
 
Pharmaceutical Industry Overview
Pharmaceutical Industry OverviewPharmaceutical Industry Overview
Pharmaceutical Industry OverviewDemetris Iacovides
 
Porter five force model analysis of merck
Porter five force model analysis of merckPorter five force model analysis of merck
Porter five force model analysis of merckTahira Sultana
 
Corporate Strategy Assignment - The Global Pharmaceutical Industry
Corporate Strategy Assignment - The Global Pharmaceutical IndustryCorporate Strategy Assignment - The Global Pharmaceutical Industry
Corporate Strategy Assignment - The Global Pharmaceutical IndustryAmany Hamza
 
A review of marketing
A review of marketingA review of marketing
A review of marketingNilesh Shah
 
Implications for indian_pharmaceuticals
Implications for indian_pharmaceuticalsImplications for indian_pharmaceuticals
Implications for indian_pharmaceuticalsAkshay Bawa
 
Porter’S Five Force Model In Pharma Industries
Porter’S Five Force Model In Pharma IndustriesPorter’S Five Force Model In Pharma Industries
Porter’S Five Force Model In Pharma IndustriesPradeep555
 
Financial Management in Pharmaceutical industry
Financial Management in Pharmaceutical industryFinancial Management in Pharmaceutical industry
Financial Management in Pharmaceutical industryDr.Richa S
 
Growth of pharmaceutical industry
Growth of pharmaceutical industryGrowth of pharmaceutical industry
Growth of pharmaceutical industrySai Datri Arige
 
Pharmaceutical Industry Environmental Analysis (Sanofi, Merck & Co.)
Pharmaceutical Industry Environmental Analysis (Sanofi, Merck & Co.)Pharmaceutical Industry Environmental Analysis (Sanofi, Merck & Co.)
Pharmaceutical Industry Environmental Analysis (Sanofi, Merck & Co.)Steven Sabo
 
The Pharmaceutical Industry and the Industrial Pharmacist: A Partnership for ...
The Pharmaceutical Industry and the Industrial Pharmacist: A Partnership for ...The Pharmaceutical Industry and the Industrial Pharmacist: A Partnership for ...
The Pharmaceutical Industry and the Industrial Pharmacist: A Partnership for ...European Industrial Pharmacists Group
 
Pharmaceutical industry in india
Pharmaceutical industry in indiaPharmaceutical industry in india
Pharmaceutical industry in indiaSomnath Surai
 
Changing trends in Indian Pharmaceutical Industry
Changing trends in Indian Pharmaceutical IndustryChanging trends in Indian Pharmaceutical Industry
Changing trends in Indian Pharmaceutical IndustryRishang Deoras
 
indian pharmaceutical industry
indian pharmaceutical industryindian pharmaceutical industry
indian pharmaceutical industryKushal Shah
 
Pharmaceutical industry-
Pharmaceutical industry-Pharmaceutical industry-
Pharmaceutical industry-minasinvest
 

What's hot (20)

Global generic pharmaceuticals market – brighter times ahead
Global generic pharmaceuticals market – brighter times aheadGlobal generic pharmaceuticals market – brighter times ahead
Global generic pharmaceuticals market – brighter times ahead
 
PROBLEMS AND PROSPECTS PHARMA PRODUCT SELLING..
PROBLEMS AND PROSPECTS PHARMA PRODUCT SELLING..PROBLEMS AND PROSPECTS PHARMA PRODUCT SELLING..
PROBLEMS AND PROSPECTS PHARMA PRODUCT SELLING..
 
Pharmaceutical Industry Overview
Pharmaceutical Industry OverviewPharmaceutical Industry Overview
Pharmaceutical Industry Overview
 
Porter five force model analysis of merck
Porter five force model analysis of merckPorter five force model analysis of merck
Porter five force model analysis of merck
 
Pharma
PharmaPharma
Pharma
 
BEACON.Dec 2013
BEACON.Dec 2013BEACON.Dec 2013
BEACON.Dec 2013
 
Corporate Strategy Assignment - The Global Pharmaceutical Industry
Corporate Strategy Assignment - The Global Pharmaceutical IndustryCorporate Strategy Assignment - The Global Pharmaceutical Industry
Corporate Strategy Assignment - The Global Pharmaceutical Industry
 
A review of marketing
A review of marketingA review of marketing
A review of marketing
 
Implications for indian_pharmaceuticals
Implications for indian_pharmaceuticalsImplications for indian_pharmaceuticals
Implications for indian_pharmaceuticals
 
Porter’S Five Force Model In Pharma Industries
Porter’S Five Force Model In Pharma IndustriesPorter’S Five Force Model In Pharma Industries
Porter’S Five Force Model In Pharma Industries
 
Indian pharma industry
Indian pharma industryIndian pharma industry
Indian pharma industry
 
Financial Management in Pharmaceutical industry
Financial Management in Pharmaceutical industryFinancial Management in Pharmaceutical industry
Financial Management in Pharmaceutical industry
 
Growth of pharmaceutical industry
Growth of pharmaceutical industryGrowth of pharmaceutical industry
Growth of pharmaceutical industry
 
Pharmaceuticals Sector Report - April 2019
Pharmaceuticals Sector Report - April 2019Pharmaceuticals Sector Report - April 2019
Pharmaceuticals Sector Report - April 2019
 
Pharmaceutical Industry Environmental Analysis (Sanofi, Merck & Co.)
Pharmaceutical Industry Environmental Analysis (Sanofi, Merck & Co.)Pharmaceutical Industry Environmental Analysis (Sanofi, Merck & Co.)
Pharmaceutical Industry Environmental Analysis (Sanofi, Merck & Co.)
 
The Pharmaceutical Industry and the Industrial Pharmacist: A Partnership for ...
The Pharmaceutical Industry and the Industrial Pharmacist: A Partnership for ...The Pharmaceutical Industry and the Industrial Pharmacist: A Partnership for ...
The Pharmaceutical Industry and the Industrial Pharmacist: A Partnership for ...
 
Pharmaceutical industry in india
Pharmaceutical industry in indiaPharmaceutical industry in india
Pharmaceutical industry in india
 
Changing trends in Indian Pharmaceutical Industry
Changing trends in Indian Pharmaceutical IndustryChanging trends in Indian Pharmaceutical Industry
Changing trends in Indian Pharmaceutical Industry
 
indian pharmaceutical industry
indian pharmaceutical industryindian pharmaceutical industry
indian pharmaceutical industry
 
Pharmaceutical industry-
Pharmaceutical industry-Pharmaceutical industry-
Pharmaceutical industry-
 

Viewers also liked

Currículo referência matemática6º ao 9º ano
Currículo referência  matemática6º ao 9º anoCurrículo referência  matemática6º ao 9º ano
Currículo referência matemática6º ao 9º anotecnicossme
 
Social Media for Lead Generation
Social Media for Lead GenerationSocial Media for Lead Generation
Social Media for Lead GenerationLeadSquared
 
Evolution of Data Analytics: the past, the present and the future
Evolution of Data Analytics: the past, the present and the futureEvolution of Data Analytics: the past, the present and the future
Evolution of Data Analytics: the past, the present and the futureVarun Nemmani
 
SENSOR BASED AUTOMATIC DRIP IRRIGATION SYSTEM
SENSOR BASED AUTOMATIC DRIP IRRIGATION SYSTEMSENSOR BASED AUTOMATIC DRIP IRRIGATION SYSTEM
SENSOR BASED AUTOMATIC DRIP IRRIGATION SYSTEMJournal For Research
 
Fodder system: Growing animal feed in 7 days without soil
Fodder system: Growing animal feed in 7 days without soilFodder system: Growing animal feed in 7 days without soil
Fodder system: Growing animal feed in 7 days without soilSamson Ogbole
 
Chatter Actions - Short Version
Chatter Actions - Short VersionChatter Actions - Short Version
Chatter Actions - Short VersionCloudTech 
 
"ΠΑΡΑΞΕΝΑ ΖΩΑ ΤΟΥ ΠΛΑΝΗΤΗ ΜΑΣ"
"ΠΑΡΑΞΕΝΑ ΖΩΑ ΤΟΥ ΠΛΑΝΗΤΗ ΜΑΣ""ΠΑΡΑΞΕΝΑ ΖΩΑ ΤΟΥ ΠΛΑΝΗΤΗ ΜΑΣ"
"ΠΑΡΑΞΕΝΑ ΖΩΑ ΤΟΥ ΠΛΑΝΗΤΗ ΜΑΣ"Χάιδω Δράκου
 

Viewers also liked (11)

Lampades
LampadesLampades
Lampades
 
εθνικός κήπος
εθνικός κήποςεθνικός κήπος
εθνικός κήπος
 
Currículo referência matemática6º ao 9º ano
Currículo referência  matemática6º ao 9º anoCurrículo referência  matemática6º ao 9º ano
Currículo referência matemática6º ao 9º ano
 
Social Media for Lead Generation
Social Media for Lead GenerationSocial Media for Lead Generation
Social Media for Lead Generation
 
Evolution of Data Analytics: the past, the present and the future
Evolution of Data Analytics: the past, the present and the futureEvolution of Data Analytics: the past, the present and the future
Evolution of Data Analytics: the past, the present and the future
 
SENSOR BASED AUTOMATIC DRIP IRRIGATION SYSTEM
SENSOR BASED AUTOMATIC DRIP IRRIGATION SYSTEMSENSOR BASED AUTOMATIC DRIP IRRIGATION SYSTEM
SENSOR BASED AUTOMATIC DRIP IRRIGATION SYSTEM
 
Fodder system: Growing animal feed in 7 days without soil
Fodder system: Growing animal feed in 7 days without soilFodder system: Growing animal feed in 7 days without soil
Fodder system: Growing animal feed in 7 days without soil
 
Chatter Actions - Short Version
Chatter Actions - Short VersionChatter Actions - Short Version
Chatter Actions - Short Version
 
κυκλοφοριακη αγωγη
κυκλοφοριακη αγωγηκυκλοφοριακη αγωγη
κυκλοφοριακη αγωγη
 
"ΠΑΡΑΞΕΝΑ ΖΩΑ ΤΟΥ ΠΛΑΝΗΤΗ ΜΑΣ"
"ΠΑΡΑΞΕΝΑ ΖΩΑ ΤΟΥ ΠΛΑΝΗΤΗ ΜΑΣ""ΠΑΡΑΞΕΝΑ ΖΩΑ ΤΟΥ ΠΛΑΝΗΤΗ ΜΑΣ"
"ΠΑΡΑΞΕΝΑ ΖΩΑ ΤΟΥ ΠΛΑΝΗΤΗ ΜΑΣ"
 
GtoPdb_ITMAT_2017
GtoPdb_ITMAT_2017GtoPdb_ITMAT_2017
GtoPdb_ITMAT_2017
 

Similar to U.S Pharma Majors Go Shopping in India

Mipm report team 3
Mipm report team 3Mipm report team 3
Mipm report team 3BiplovRoy2
 
Overview of the Pharma industry
Overview of the Pharma industryOverview of the Pharma industry
Overview of the Pharma industrykeyursavalia
 
Mipm report team 3
Mipm report team 3Mipm report team 3
Mipm report team 3BiplovRoy2
 
Indian Pharmaceutical Export Market - Top Export Destinations for Indian Phar...
Indian Pharmaceutical Export Market - Top Export Destinations for Indian Phar...Indian Pharmaceutical Export Market - Top Export Destinations for Indian Phar...
Indian Pharmaceutical Export Market - Top Export Destinations for Indian Phar...Irish Pereira
 
Contract Manufacturing In India
Contract Manufacturing  In IndiaContract Manufacturing  In India
Contract Manufacturing In Indiakaushik2541984
 
Indian pharma outlook
Indian pharma outlookIndian pharma outlook
Indian pharma outlookAkshay Bawa
 
Indian Pharmaceutical Industry
Indian Pharmaceutical IndustryIndian Pharmaceutical Industry
Indian Pharmaceutical IndustryChandni Sahgal
 
Industry Monitor - Indian Healthcare Sector October 2014 (2)
Industry Monitor - Indian Healthcare Sector October 2014 (2)Industry Monitor - Indian Healthcare Sector October 2014 (2)
Industry Monitor - Indian Healthcare Sector October 2014 (2)Debasish M Banerjee
 
Drugs and pharmaceuticals
Drugs and pharmaceuticalsDrugs and pharmaceuticals
Drugs and pharmaceuticalsThariq Asharaf
 
Indian Pharma - An Overview by IDMA Secretary General Daara B Patel
Indian Pharma - An Overview by IDMA Secretary General Daara B PatelIndian Pharma - An Overview by IDMA Secretary General Daara B Patel
Indian Pharma - An Overview by IDMA Secretary General Daara B PatelAnup Soans
 
A review of marketing
A review of marketingA review of marketing
A review of marketingNilesh Shah
 
Project on Production and Packaging in Pharmaceutical Industry Emcure By Nikh...
Project on Production and Packaging in Pharmaceutical Industry Emcure By Nikh...Project on Production and Packaging in Pharmaceutical Industry Emcure By Nikh...
Project on Production and Packaging in Pharmaceutical Industry Emcure By Nikh...Nikhil Dhawan
 
Equity research report himanshi and rashmi
Equity research report himanshi and rashmiEquity research report himanshi and rashmi
Equity research report himanshi and rashmiHimanshiKarmakar1
 
A Study of generic drugs
A Study of generic drugsA Study of generic drugs
A Study of generic drugsSantosh Salgare
 

Similar to U.S Pharma Majors Go Shopping in India (20)

Mipm report team 3
Mipm report team 3Mipm report team 3
Mipm report team 3
 
Overview of the Pharma industry
Overview of the Pharma industryOverview of the Pharma industry
Overview of the Pharma industry
 
Mipm report team 3
Mipm report team 3Mipm report team 3
Mipm report team 3
 
Presentation
PresentationPresentation
Presentation
 
Indian Pharmaceutical Export Market - Top Export Destinations for Indian Phar...
Indian Pharmaceutical Export Market - Top Export Destinations for Indian Phar...Indian Pharmaceutical Export Market - Top Export Destinations for Indian Phar...
Indian Pharmaceutical Export Market - Top Export Destinations for Indian Phar...
 
Jom 06 02_012
Jom 06 02_012Jom 06 02_012
Jom 06 02_012
 
Contract Manufacturing In India
Contract Manufacturing  In IndiaContract Manufacturing  In India
Contract Manufacturing In India
 
Api china-2013
Api china-2013Api china-2013
Api china-2013
 
Indian pharma outlook
Indian pharma outlookIndian pharma outlook
Indian pharma outlook
 
Indian Pharmaceutical Industry
Indian Pharmaceutical IndustryIndian Pharmaceutical Industry
Indian Pharmaceutical Industry
 
Industry Monitor - Indian Healthcare Sector October 2014 (2)
Industry Monitor - Indian Healthcare Sector October 2014 (2)Industry Monitor - Indian Healthcare Sector October 2014 (2)
Industry Monitor - Indian Healthcare Sector October 2014 (2)
 
ASSOCHAM_White_paper_091106
ASSOCHAM_White_paper_091106ASSOCHAM_White_paper_091106
ASSOCHAM_White_paper_091106
 
Drugs and pharmaceuticals
Drugs and pharmaceuticalsDrugs and pharmaceuticals
Drugs and pharmaceuticals
 
Indian Pharma - An Overview by IDMA Secretary General Daara B Patel
Indian Pharma - An Overview by IDMA Secretary General Daara B PatelIndian Pharma - An Overview by IDMA Secretary General Daara B Patel
Indian Pharma - An Overview by IDMA Secretary General Daara B Patel
 
A review of marketing
A review of marketingA review of marketing
A review of marketing
 
Project on Production and Packaging in Pharmaceutical Industry Emcure By Nikh...
Project on Production and Packaging in Pharmaceutical Industry Emcure By Nikh...Project on Production and Packaging in Pharmaceutical Industry Emcure By Nikh...
Project on Production and Packaging in Pharmaceutical Industry Emcure By Nikh...
 
Nikroxx file pdf
Nikroxx file pdfNikroxx file pdf
Nikroxx file pdf
 
Nikroxx file pdf
Nikroxx file pdfNikroxx file pdf
Nikroxx file pdf
 
Equity research report himanshi and rashmi
Equity research report himanshi and rashmiEquity research report himanshi and rashmi
Equity research report himanshi and rashmi
 
A Study of generic drugs
A Study of generic drugsA Study of generic drugs
A Study of generic drugs
 

Recently uploaded

Best Basmati Rice Manufacturers in India
Best Basmati Rice Manufacturers in IndiaBest Basmati Rice Manufacturers in India
Best Basmati Rice Manufacturers in IndiaShree Krishna Exports
 
Value Proposition canvas- Customer needs and pains
Value Proposition canvas- Customer needs and painsValue Proposition canvas- Customer needs and pains
Value Proposition canvas- Customer needs and painsP&CO
 
Unlocking the Secrets of Affiliate Marketing.pdf
Unlocking the Secrets of Affiliate Marketing.pdfUnlocking the Secrets of Affiliate Marketing.pdf
Unlocking the Secrets of Affiliate Marketing.pdfOnline Income Engine
 
VIP Kolkata Call Girl Howrah 👉 8250192130 Available With Room
VIP Kolkata Call Girl Howrah 👉 8250192130  Available With RoomVIP Kolkata Call Girl Howrah 👉 8250192130  Available With Room
VIP Kolkata Call Girl Howrah 👉 8250192130 Available With Roomdivyansh0kumar0
 
HONOR Veterans Event Keynote by Michael Hawkins
HONOR Veterans Event Keynote by Michael HawkinsHONOR Veterans Event Keynote by Michael Hawkins
HONOR Veterans Event Keynote by Michael HawkinsMichael W. Hawkins
 
VIP Call Girls In Saharaganj ( Lucknow ) 🔝 8923113531 🔝 Cash Payment (COD) 👒
VIP Call Girls In Saharaganj ( Lucknow  ) 🔝 8923113531 🔝  Cash Payment (COD) 👒VIP Call Girls In Saharaganj ( Lucknow  ) 🔝 8923113531 🔝  Cash Payment (COD) 👒
VIP Call Girls In Saharaganj ( Lucknow ) 🔝 8923113531 🔝 Cash Payment (COD) 👒anilsa9823
 
Call Girls Pune Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Pune Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Pune Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Pune Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
Understanding the Pakistan Budgeting Process: Basics and Key Insights
Understanding the Pakistan Budgeting Process: Basics and Key InsightsUnderstanding the Pakistan Budgeting Process: Basics and Key Insights
Understanding the Pakistan Budgeting Process: Basics and Key Insightsseribangash
 
Monthly Social Media Update April 2024 pptx.pptx
Monthly Social Media Update April 2024 pptx.pptxMonthly Social Media Update April 2024 pptx.pptx
Monthly Social Media Update April 2024 pptx.pptxAndy Lambert
 
Call Girls In DLf Gurgaon ➥99902@11544 ( Best price)100% Genuine Escort In 24...
Call Girls In DLf Gurgaon ➥99902@11544 ( Best price)100% Genuine Escort In 24...Call Girls In DLf Gurgaon ➥99902@11544 ( Best price)100% Genuine Escort In 24...
Call Girls In DLf Gurgaon ➥99902@11544 ( Best price)100% Genuine Escort In 24...lizamodels9
 
0183760ssssssssssssssssssssssssssss00101011 (27).pdf
0183760ssssssssssssssssssssssssssss00101011 (27).pdf0183760ssssssssssssssssssssssssssss00101011 (27).pdf
0183760ssssssssssssssssssssssssssss00101011 (27).pdfRenandantas16
 
Mondelez State of Snacking and Future Trends 2023
Mondelez State of Snacking and Future Trends 2023Mondelez State of Snacking and Future Trends 2023
Mondelez State of Snacking and Future Trends 2023Neil Kimberley
 
Mysore Call Girls 8617370543 WhatsApp Number 24x7 Best Services
Mysore Call Girls 8617370543 WhatsApp Number 24x7 Best ServicesMysore Call Girls 8617370543 WhatsApp Number 24x7 Best Services
Mysore Call Girls 8617370543 WhatsApp Number 24x7 Best ServicesDipal Arora
 
Grateful 7 speech thanking everyone that has helped.pdf
Grateful 7 speech thanking everyone that has helped.pdfGrateful 7 speech thanking everyone that has helped.pdf
Grateful 7 speech thanking everyone that has helped.pdfPaul Menig
 
VIP Call Girl Jamshedpur Aashi 8250192130 Independent Escort Service Jamshedpur
VIP Call Girl Jamshedpur Aashi 8250192130 Independent Escort Service JamshedpurVIP Call Girl Jamshedpur Aashi 8250192130 Independent Escort Service Jamshedpur
VIP Call Girl Jamshedpur Aashi 8250192130 Independent Escort Service JamshedpurSuhani Kapoor
 
Ensure the security of your HCL environment by applying the Zero Trust princi...
Ensure the security of your HCL environment by applying the Zero Trust princi...Ensure the security of your HCL environment by applying the Zero Trust princi...
Ensure the security of your HCL environment by applying the Zero Trust princi...Roland Driesen
 
Yaroslav Rozhankivskyy: Три складові і три передумови максимальної продуктивн...
Yaroslav Rozhankivskyy: Три складові і три передумови максимальної продуктивн...Yaroslav Rozhankivskyy: Три складові і три передумови максимальної продуктивн...
Yaroslav Rozhankivskyy: Три складові і три передумови максимальної продуктивн...Lviv Startup Club
 
Sales & Marketing Alignment: How to Synergize for Success
Sales & Marketing Alignment: How to Synergize for SuccessSales & Marketing Alignment: How to Synergize for Success
Sales & Marketing Alignment: How to Synergize for SuccessAggregage
 

Recently uploaded (20)

Best Basmati Rice Manufacturers in India
Best Basmati Rice Manufacturers in IndiaBest Basmati Rice Manufacturers in India
Best Basmati Rice Manufacturers in India
 
Value Proposition canvas- Customer needs and pains
Value Proposition canvas- Customer needs and painsValue Proposition canvas- Customer needs and pains
Value Proposition canvas- Customer needs and pains
 
Unlocking the Secrets of Affiliate Marketing.pdf
Unlocking the Secrets of Affiliate Marketing.pdfUnlocking the Secrets of Affiliate Marketing.pdf
Unlocking the Secrets of Affiliate Marketing.pdf
 
VIP Kolkata Call Girl Howrah 👉 8250192130 Available With Room
VIP Kolkata Call Girl Howrah 👉 8250192130  Available With RoomVIP Kolkata Call Girl Howrah 👉 8250192130  Available With Room
VIP Kolkata Call Girl Howrah 👉 8250192130 Available With Room
 
HONOR Veterans Event Keynote by Michael Hawkins
HONOR Veterans Event Keynote by Michael HawkinsHONOR Veterans Event Keynote by Michael Hawkins
HONOR Veterans Event Keynote by Michael Hawkins
 
VIP Call Girls In Saharaganj ( Lucknow ) 🔝 8923113531 🔝 Cash Payment (COD) 👒
VIP Call Girls In Saharaganj ( Lucknow  ) 🔝 8923113531 🔝  Cash Payment (COD) 👒VIP Call Girls In Saharaganj ( Lucknow  ) 🔝 8923113531 🔝  Cash Payment (COD) 👒
VIP Call Girls In Saharaganj ( Lucknow ) 🔝 8923113531 🔝 Cash Payment (COD) 👒
 
Nepali Escort Girl Kakori \ 9548273370 Indian Call Girls Service Lucknow ₹,9517
Nepali Escort Girl Kakori \ 9548273370 Indian Call Girls Service Lucknow ₹,9517Nepali Escort Girl Kakori \ 9548273370 Indian Call Girls Service Lucknow ₹,9517
Nepali Escort Girl Kakori \ 9548273370 Indian Call Girls Service Lucknow ₹,9517
 
Call Girls Pune Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Pune Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Pune Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Pune Just Call 9907093804 Top Class Call Girl Service Available
 
Understanding the Pakistan Budgeting Process: Basics and Key Insights
Understanding the Pakistan Budgeting Process: Basics and Key InsightsUnderstanding the Pakistan Budgeting Process: Basics and Key Insights
Understanding the Pakistan Budgeting Process: Basics and Key Insights
 
Monthly Social Media Update April 2024 pptx.pptx
Monthly Social Media Update April 2024 pptx.pptxMonthly Social Media Update April 2024 pptx.pptx
Monthly Social Media Update April 2024 pptx.pptx
 
Call Girls In DLf Gurgaon ➥99902@11544 ( Best price)100% Genuine Escort In 24...
Call Girls In DLf Gurgaon ➥99902@11544 ( Best price)100% Genuine Escort In 24...Call Girls In DLf Gurgaon ➥99902@11544 ( Best price)100% Genuine Escort In 24...
Call Girls In DLf Gurgaon ➥99902@11544 ( Best price)100% Genuine Escort In 24...
 
VVVIP Call Girls In Greater Kailash ➡️ Delhi ➡️ 9999965857 🚀 No Advance 24HRS...
VVVIP Call Girls In Greater Kailash ➡️ Delhi ➡️ 9999965857 🚀 No Advance 24HRS...VVVIP Call Girls In Greater Kailash ➡️ Delhi ➡️ 9999965857 🚀 No Advance 24HRS...
VVVIP Call Girls In Greater Kailash ➡️ Delhi ➡️ 9999965857 🚀 No Advance 24HRS...
 
0183760ssssssssssssssssssssssssssss00101011 (27).pdf
0183760ssssssssssssssssssssssssssss00101011 (27).pdf0183760ssssssssssssssssssssssssssss00101011 (27).pdf
0183760ssssssssssssssssssssssssssss00101011 (27).pdf
 
Mondelez State of Snacking and Future Trends 2023
Mondelez State of Snacking and Future Trends 2023Mondelez State of Snacking and Future Trends 2023
Mondelez State of Snacking and Future Trends 2023
 
Mysore Call Girls 8617370543 WhatsApp Number 24x7 Best Services
Mysore Call Girls 8617370543 WhatsApp Number 24x7 Best ServicesMysore Call Girls 8617370543 WhatsApp Number 24x7 Best Services
Mysore Call Girls 8617370543 WhatsApp Number 24x7 Best Services
 
Grateful 7 speech thanking everyone that has helped.pdf
Grateful 7 speech thanking everyone that has helped.pdfGrateful 7 speech thanking everyone that has helped.pdf
Grateful 7 speech thanking everyone that has helped.pdf
 
VIP Call Girl Jamshedpur Aashi 8250192130 Independent Escort Service Jamshedpur
VIP Call Girl Jamshedpur Aashi 8250192130 Independent Escort Service JamshedpurVIP Call Girl Jamshedpur Aashi 8250192130 Independent Escort Service Jamshedpur
VIP Call Girl Jamshedpur Aashi 8250192130 Independent Escort Service Jamshedpur
 
Ensure the security of your HCL environment by applying the Zero Trust princi...
Ensure the security of your HCL environment by applying the Zero Trust princi...Ensure the security of your HCL environment by applying the Zero Trust princi...
Ensure the security of your HCL environment by applying the Zero Trust princi...
 
Yaroslav Rozhankivskyy: Три складові і три передумови максимальної продуктивн...
Yaroslav Rozhankivskyy: Три складові і три передумови максимальної продуктивн...Yaroslav Rozhankivskyy: Три складові і три передумови максимальної продуктивн...
Yaroslav Rozhankivskyy: Три складові і три передумови максимальної продуктивн...
 
Sales & Marketing Alignment: How to Synergize for Success
Sales & Marketing Alignment: How to Synergize for SuccessSales & Marketing Alignment: How to Synergize for Success
Sales & Marketing Alignment: How to Synergize for Success
 

U.S Pharma Majors Go Shopping in India

  • 1. Varun Nemmani June 2016 University of Missouri- Kansas City 1 US Pharma Majors Go Shopping in India: A Know-How Guide to Acquire & Invest in the Indian Pharmaceutical Industry Abstract: The present paper deals with the topic of the evolving landscape of the global pharmaceutical industry, where the manufacturing and other vital operations do not take place any longer in the conventional markets but have shifted to more cost-effective, emerging markets in the world. In the wake of this transformation there has been a sudden rush in the industry to form global strategic alliances/ partnerships and to acquire pharma companies. This trend of consolidation has caught up with firms in both developed and emerging economies alike, to acquire the resources and capabilities that would equip them with a sustainable competitive edge in a hyper-competitive market. This research paper is an attempt at understanding- the forces that have caused the shift, why the time is ripe for pharmaceutical firms in the US to expand beyond their comfort zone and enter the race to expand into emerging markets- especially into India, the best route to enter the Indian industry (investments and acquisitions), whom and how to select for mergers & acquisitions, understanding the various opportunities and issues of operating in the Indian market, the various elements that make up the Indian industry and the various factors at play there, which make it unique in ways more than one, strategies to capture the Indian market and how to transform the organizational culture, manufacturing practices and supply chain to make the acquisition not only a success story but also to ensure the company abides by the rules and regulations of the USFDA. Last but not the least, the paper would also examine the exit strategies, in case the acquisition doesn’t turn out quite right.
  • 2. Varun Nemmani June 2016 University of Missouri- Kansas City 2 Introduction: The latest trend in the global pharmaceutical industry is of mergers, acquisitions, alliances and partnerships to cooperate with each other. The major reasons behind such a move of consolidation in the industry is that Research & Development costs are spiraling up, developing drugs is time consuming, the development phase can be stuck in the pipeline for years together, results are highly uncertain and drugs can often fail at the clinical trial phase as well, the possibility of finding the ‘blockbuster’ drug is quite rare and more often than not access to international markets if often draught with various regulatory issues as well as severe competition. Not all companies have the necessary funds, skills and capabilities to achieve the desired level of innovation and manufacturing capacities. When a drug is in the pipeline, with a lot of investment locked in, sustainability can become an issue. The desperation to survive and to continue earning revenues to keep the firm running against all odds, often makes these businesses turn a blind eye to quality and regulatory issues. This is when a pharmaceutical company earns the risk of facing the wrath of regulatory bodies such as USFDA, which can often lead to their drugs being banned from the market. Hence a lot of pharma companies in the world are seeking M&A’s and alliances on a global scale. The phenomenon of ‘consolidation’ in the pharma industry is a reality, it is here to stay and is inevitable. This would enable them to not only acquire knowledge and gain skilled workforce in the emerging economies but also leverage the low cost structure of the developing markets. These international alliances would help a multinational company transform into a transnational organization (Anonymous, 2006). At this point, the question that begs to be asked is, why are American firms shifting their operations and manufacturing base from their home turf to emerging markets like India? The answer is that- i) revenues of US based companies are decreasing because of fall in prices of generic drugs, ii) more generic drugs are being introduced into the market, iii) most of which are being pumped from low-cost markets in to the US market, iv) M&A’s and global alliances are reducing the number of firms manufacturing in the United States and v) the most important and perhaps an obvious reason behind all this is the rising costs of manufacturing costs in the US (Greene, 2007). There has been surging interest in the field of generics for a lot of reasons for quite some time now. According to the reports of the US Trade Commission, of the 10 largest generic firms in the world, 9 belong to the US and these firms are out to capture generic drug manufacturers in low-cost
  • 3. Varun Nemmani June 2016 University of Missouri- Kansas City 3 markets like that of India. Indian pharma companies have specialized the manufacture of generics long before it became a hot topic of the global pharma industry. Another point of interest is the cost of generics. They cost anywhere between 30-80% cheaper than the branded drugs and as a result, close to 56% of the drugs prescribed by doctors in the US are generics and sales of generics grew by 21% between the years 2004 and 2005 (Greene, 2007). Pharmaceutical companies specializing in innovation too have diverted their attention towards generics now as their patented drugs are about to lose their protection (patent expiry). For example, Pfizer, which had exited the generics business long ago, re-entered the field of generics with the creation of ‘Established Products’ in 2008 for manufacturing generics and later in 2009 and 2010 Pfizer had signed contracts with two Indian firms for the manufacture and supply of vaccines and anti- cancer drugs (Harding, 2010). Now, let’s dissect the Indian pharmaceutical industry to understand the sudden interest it has been garnering from its international counterparts. The Indian Pharmaceutical Industry: The Indian pharma industry is the third largest in the world in terms of the volume of exports and ranks thirteenth in terms of value of its exports (India Brand Equity Foundation, 2016). The size of the Indian pharma industry is estimated to be around $ 20 billion (Indiatimes, 2016) and the export turnover of the industry is over $ 10 billion and it exports to more than 200 countries (Taylor, 2014). The CAGR of the industry is 14%, whereas the growth rates of the pharma industries in EU and US hover between 1-6% (Sharma, 2010). Up to 40% of the generic drugs available in the US market come from India (Taylor, 2014) and as of 2014, the total value of the exports to the US stands at $ 3.45 billion. Around 520 Indian firms are registered with USFDA (Business line, 2015). SWOT analysis of the industry: Strengths of the Indian Pharmaceutical Industry:  The biggest strength is perhaps its cost effectiveness and its capability to produce drugs at the cheapest rate possible. According to the estimates of the US Trade Commission, the labor costs are 50-55% cheaper in India than they are in the US, infrastructure costs are 40% cheaper, the fixed costs in the Indian pharma industry are less by 12-20%, cost of
  • 4. Varun Nemmani June 2016 University of Missouri- Kansas City 4 developing bulk drugs is 60% less in India and the construction of a production plant costs 40% less.  Most Indian pharma companies have immense experience in the field of reverse engineering of drugs, which is a huge asset when it comes to the manufacture of generics.  The industry specializes in ‘contract manufacturing’.  India boasts of a large pool of English speaking, technically skilled workers who come at a low cost.  Rapidly developing and evolving infrastructure.  Reformations in Patent laws to the advantage of firms looking to manufacture new drugs (Greene, 2007). Weaknesses of the Indian Pharmaceutical Industry:  Huge investment gap in R&D and other innovation projects. As a result, it lags behind in innovation and is hugely restricted to replicating existing drugs whose patents have expired (Business line, 2016).  The pharma industry and its supply chain are both highly fragmented.  The Indian government imposes ‘price ceilings’ on certain important and lifesaving drugs  The ever increasing problem of counterfeit drugs in the market.  Absence of strong and established logistics players in the industry, as a result of which the cost of distribution is high (Greene, 2007). Close to half of the costs in the supply chain arise from logistics alone (Shetty, 2015).  Lack of proper clinical trials.  Lack of documentation of the processes involved.  Insufficient information and compensation to patients participating in the clinical trials (Taylor, 2014). Opportunities in the Indian Pharmaceutical Industry:  The fact that the Indian industry already boasts of such impressive exports and that the exports are poised to touch the $ 50 billion mark by 2020 speaks volumes of the immense opportunities that the Indian industry holds.  Evolving and ever increasing demand in the Indian domestic market.
  • 5. Varun Nemmani June 2016 University of Missouri- Kansas City 5  $ 40 billion worth patented drugs have gone off patent in the year 2010 and many more drugs will follow suit. Yet again this presents an opportunity to the companies to manufacture generic drugs.  The capital requirements to start operations in India are very low.  The barriers of entry are low as well (Taylor, 2014).  The government provides tax benefits for companies investing in the Indian industry.  Changing patent laws.  Reduction of custom duties.  India has a huge untapped market for drugs.  Huge and diverse population makes India an ideal location for conducting clinical trials and R&D experiments (Shetty, 2015). Threats facing the industry:  In the year 2014, nineteen warning letters were issued by the USFDA, of which eight were issued to Indian pharma companies according to a survey by Ernst and Young (Business line, 2015).  Not all firms have USFDA approvable facilities (Harding, 2010).  Shortage of funds, staff and mounting work pressure on the existing staff leading to false and inaccurate documentation and manufacturing practices (Business line, 2015).  Expanding interest of the pharma companies towards other low-cost emerging markets such as Mexico, Brazil, Chile, Romania, South Africa, Singapore, South Korea and Australia (Harding, 2010).  Increasing competition from China, which is able to manufacture intermediates and bulk drugs at a much cheaper rate and a lot faster too. The dumping of Chinese drugs in the Indian market has led to the closure of some Indian businesses as well.  Lax policies and lack of sufficient regulatory procedures to look into the irregularities of the pharmaceutical industry (Lalitha, 2002). The weaknesses, threats and other challenges of the Indian pharma industry are certainly outweighed by its strengths and opportunities. For these very reasons the global pharma majors can’t ignore the unique opportunities India bestows upon those who would want to invest in it
  • 6. Varun Nemmani June 2016 University of Missouri- Kansas City 6 (Shetty, 2015). It is estimated that these international players will eventually capture 60% of the Indian pharma industry in the near future and these M&A’s will infuse cash and inject innovation into the industry (Business line, 2016), i.e., will only enable the Indian firms to invest more in their R&D programs, to move up the value chain and diversify their product portfolio (Greene, 2007). Why is it so crucial for the Indian pharma industry to attract foreign investments? We have already seen that most of the Indian firms are strapped for cash and hence aren’t able to move up the ladder of innovation or stick to the GMP guidelines laid down by the USFDA. It isn’t just a random observation that investments into manufacturing facilities and innovation projects are highly correlated to the export performance of a firm. It has been validated by a study conducted by Rentala and Anand in 2014 on 142 Indian pharma companies using the OLS and Quantile Regression methods. The analysis revealed positive correlation between- efforts/ investments put into R&D projects, age of the firm, monetary compensation given to employees, fixed assets of the firm, import of capital goods/ raw materials and exports of the firm. Higher the efforts, larger the investment into innovation programs and GMP higher the value/ volume of exports (Rentala & Anand, 2014). Impact of competition on R&D in the Indian pharma industry: Let us try and understand the impact of competition within the industry on the R&D expenditure of a firm. A study has found that there is an Inverted-U relationship between amount of investment/intensity of R&D efforts and market concentration in the Indian pharma industry. Essentially this means that pharma companies try to spend a lot on R&D even when their market share is low, which in turn reflects the magnitude of competition in the industry. As the market share and profit margins of a firm go up, so does its spending on R&D. This has led to the Indian firms clamor for collaboration and alliances in the field of R&D, primarily to decrease their cost of innovation and lower their risk associated with the development of new drugs (Das & Das, 2015). Mode of entry into the Indian pharma industry: Having understood the various facets of the industry and the various forces at play, let’s examine the best ways to enter it.
  • 7. Varun Nemmani June 2016 University of Missouri- Kansas City 7 The Government of India allows 100% Foreign Direct Investment in greenfield pharmaceuticals (a greenfield investment is one when a MNC invests in another country to start a new manufacturing facility) and 74% FDI through the brownfield mode of investment (a type of investment where a MNC purchases existing plant or facilities to start operations in a foreign country). Considering the present market circumstances (stringent requirements of the USFDA, market dynamics in the US and India and the needs of Indian companies) it is advisable that US firms enter the Indian market through the brownfield mode of investment. In fact, over 96% of the FDI in the pharma sector flowed in through brownfield investments (Indiatimes, 2016). That was the macro-economic picture of the mode of entry. Now, let’s look at the micro-economic picture to examine the various models of business that a US firm can choose from depending on its requirements. Figure 1: The various business models that global pharma players can consider before entering the Indian market. Various companies from the US have already entered the Indian industry using one of the models, depending on their needs (Shetty, 2015). a) Outsourcing: Perhaps this is one of the oldest business models now and is quite safe and risk free. Also, doesn’t entail a lot of investment. A lot of US companies have tried this model before and continue to do so. Ex: GVK Bio takes up contract research for US and European firms. Business Models outsourcing
  • 8. Varun Nemmani June 2016 University of Missouri- Kansas City 8 b) Licensing agreements: In this model, the firm that innovates the drug issues licenses to firms in other countries either to manufacture or market them. This way the costs of manufacturing and commercializing/marketing the drugs aren’t borne by the innovator firm any longer, but they continue to yield profits through retained ownership and royalty on licensing agreements. c) Franchising: This mode of entry is more common in the retailing format of the pharma industry. Government of India allows companies to start their own retail pharmacy stores and franchise them to interested parties or partner with existing retail players. Ex: Medicine Shoppe International, a US based firm, has already entered the retail industry with numerous stores all over urban India. Fortis Healthcare too has made its entry into the Indian market with about 1000 stores by 2012. d) Joint Ventures: A more common option for firms looking to partner with local businesses to gain advantage of their experience and knowledge of the local business environment. Ex: India based CPL Biologicals will develop drugs for Cadila Pharmaceuticals and Novavax using their proprietary formulae and technology. e) Partially or Wholly owned subsidiaries: Pfizer has a stake of 72% in its India subsidiary and Novartis fully owns two subsidiaries in India, which go by the names- Novartis Consumer Health Private limited and Sandoz India Private Limited. The advantage of a wholly owned subsidiary is that there’s very little risk of losing critical information about technology and operation processes and they often get some tax advantages well (Shetty, 2015). Strategies to capture the Indian pharmaceutical market: No merger or acquisition can be successful or complete without the knowledge of capturing the domestic market. India’s domestic consumption of medicines is rising with changing demographics and lifestyles and this translates into a huge market/ opportunity for American firms looking to expand into India. More often than not the MNC’s might not have to look much beyond the Indian market frontiers for their sales and revenues in the future (Shetty, 2015). An article by McKinsey had analyzed the Brazilian pharma industry and had formulated various strategies to capture the same. In ways more than one, India and Brazil share a lot of similarities. Their economies are at a similar juncture and they face similar challenges and opportunities in
  • 9. Varun Nemmani June 2016 University of Missouri- Kansas City 9 growth. The industries in both the economies are currently following a similar growth trajectory and that is the reason why the strategies formulated to capture the Brazilian pharma market are applicable to the Indian scenario as well. In order to capture the market and devise strategies accordingly, one needs to classify and view the pharma market as being made of three different sub-entities- Retail pharma market, Institutional Public market and Institutional Private market. Let us now analyze the key drivers of each segment and the strategies to capture them (Afonso, Dreszer, Francis, & Ramos, 2015). Figure 2: Illustration of the three classifications or sub-entities in the pharmaceutical market A. Retail Market:  Key Drivers of this segment- The average disposable income per person is rising, the population is growing, trade discounts and penetration of generics.  Strategies to capture this segment- Establish relationship/ partnership with local companies, suppliers, distributors, wholesalers and retailers, ensure supply of low cost drugs as India is a cost conscious and cost sensitive market, reach out to consumers in mid- sized cities (as this is where most of the growth would be in the future), also this would require the MNC’s to create new capabilities and supply chain maps to penetrate the market better, identify segments of population that would most probably use medicines and target them accordingly and develop ‘customer centric supply chains’ by going beyond the sales of medicines by tracking and monitoring the health of their consumers, develop awareness programs about diseases & how to manage them better and supply of health monitoring Pharmaceutical Market Retail Market Institutional Public Market Insitutional Private Market
  • 10. Varun Nemmani June 2016 University of Missouri- Kansas City 10 devices- these strategies would not only help increase sales but also give a fillip to the image of the pharma company (Afonso et al., 2015). B. Institutional Public Market:  Key drivers of this segment- GDP growth and increased government spending on health as a percentage of GDP (Worldbank, 2015). The federal government has asked the states to increase their funding on health (Kalra, 2015). Proactive policies to attract more FDI into this sector, relaxation of licensing policies and quicker approvals to start the manufacturing operations. Also, the new patent laws are attracting more foreign investment (Invest India, 2012).  Strategies to capture this segment- the MNC’s need to understand how public hospitals work and how the doctors there prescribe medicines to their patients, develop resources and capabilities to strike a relation with these institutions/ doctors for a more direct approach to reduce barriers/ middlemen, this will lead to increased prescriptions and sales, it is better not to deal with middle men working for the public hospitals or local/federal governments (Afonso et al., 2015). C. Institutional Private Market:  Key drivers of this segment- increasing expenses on hospitalization and therapies.  Strategies to capture this segment- MNC’s should invest time and resources to better the individual consumer, private hospitals and also the health insurance providers. Should understand the needs and behavior of consumers and also what drives the doctors to prescribe certain drugs. The focus of the MNC should be towards understanding and dealing with clinical operations and nursing departments in private hospitals and pharmacy stores as well. Dealing with health insurance providers would give the firms a competitive edge, enabling them to penetrate the market better (Afonso et al., 2015). Major acquisitions in the Indian Pharma sector: The story of M&A’s with Indian companies is not a new one. In fact, it has been happening at a very fast rate over the last four years. Here’s the list of some of the most famous acquisitions in the Indian industry-
  • 11. Varun Nemmani June 2016 University of Missouri- Kansas City 11 1. Mylan Labs of US had bought 71.5% equity in Matrix Labs of India 2. A German health care group had acquired 73.3% stake in Dabur Pharma 3. Ranbaxy was bought by Japan based Daiichi Sankyo 4. French Pharma company- Sanofi Pasteur had bought Shanta Biotechnics (Sharma, 2010). 5. Chinese firm Fosun had recently acquired 86% stake in Gland Pharma (Economic times, 2016). But, not all acquisitions have a happy ending, resulting in profits. Some acquisitions in the Indian pharma industry had to be terminated half way through for a plenty of reasons. Let’s look at two such stories to see what went wrong with the acquisition, how to avert those mistakes while acquiring an Indian firm and other critical lessons to be learnt from their experiences, as Otto von Bismarck once said “the wise man learns from the mistakes of others”. I) Daiichi Sankyo sells Ranbaxy: The story of Daiichi Sankyo’s acquisition of Ranbaxy is one of a failure. When the Japanese firm bought Ranbaxy five years ago, it expected the acquisition to fetch them billions of dollars in return, but instead it cost them billions. The reason behind this is the USFDA decision of blocking Ranbaxy’s products. The reasons behind the ban were shocking to say the least- the drugs were adulterated, their labs lacked some critical amenities, dysfunctional doors and windows, unhygienic conditions in the lab, small shards of glass inside pills. The workers in Ranbaxy’s plants had no training whatsoever and were instructed to keep the production running with continuous cuts in funding, over dependence on temporary workers, lack of inspections and false/ inaccurate test results (McLain, 2014). Daiichi Sankyo found that the various departments in Ranbaxy were functioning in ‘silos’ and as a result there was no flow of information or communication between departments and lack of documentation of the processes in the company. Though the Japanese firm had tried to bring about some transformation in the culture of the organization, they had to sell the organization, as every passing day with Ranbaxy only meant mounting losses for Daiichi Sankyo. To curtail their losses further, Daiichi Sankyo sells Ranbaxy to Sun Pharmaceuticals, the largest manufacturer of drugs and vaccines in India (Mitra, 2013).
  • 12. Varun Nemmani June 2016 University of Missouri- Kansas City 12 But, even Sun Pharma isn’t immune from the warning letters of USFDA. Sterility in their manufacturing plants was a thing of concern for FDA officials. Today, Sun Pharma is actively seeking large foreign investments in the fields of employee training, process automation, quality control mechanisms and clinical trials (Kazmin, 2015). II) Germany’s Fresenius Kabi gets FDA warning: The German company had acquired 73% stake in India’s Dabur Pharma way back in 2008 (Economic times, 2008). They had to recall their cancer treatment drugs being shipped to the US after discovering cross-contamination of drugs. This led to the firm losing some share in the market, which analysts say will take time to recover and had a moderate impact on their finances and share prices. Perhaps the biggest impact was that they halt their production, although it was just temporary (Singh, 2010). The problem was that the quality control staff and other management officials had manipulated and hid QC data which led to a series of problems for the firm (Stanton, 2014). Lessons to be learnt from these debacles: Daiichi Sankyo’s former head of pharma research, Hidemi Minami has some excellent advice- there should be seamless flow of information between the manufacturing, R&D and marketing departments and must have mutual consensus throughout the process including the product launch. The various jobs in the organization need to be stitched together for a product profile that’s ideal for the market. There should be ample emphasis on teamwork and transparency at the workplace. Formation of cross-functional teams to enable flexibility in the organization. There should be synergy and consensus between the top management and employees of the organization. Indian companies usually have the ‘top-down’ approach in management and MNC’s expanding into India should strike a balance between the top-down and consensus approaches (Mitra, 2013). For a problem like the once faced by the German firm Fresenius Kabi, MNC’s could adopt the following strategies to avert those problems- there should be a third party audit of the firm to be acquired and should seek a detailed report of the operating and manufacturing practices of the firm, check if the firm already adheres to GMP’s, assess the management structure and organizational culture and check if they are compatible; random and regular third party inspections of the manufacturing site after the acquisition and have the reports sent to the headquarters, have a single,
  • 13. Varun Nemmani June 2016 University of Missouri- Kansas City 13 cohesive work culture throughout the organization to ensure uniform implementation of best practices and to stick to USFDA regulations; have regular training programs for employees on GMP’s; more importantly, be prepared for eventualities such as the one faced by the German firm and have a Business Continuity Plan, so that there is swift damage control to avoid huge disruptions to the business operations; Data Integrity Assessments should be carried out in regular intervals to inspect the level of compliance with USFDA and GMP’s (Business line, 2015). India’s pharma supply chain and how to re-design it: The pharma supply chain in India is highly fragmented and so is the distribution network, leading to heavy dependence on retailers in the chain. The retailers are having to stock more inventory than required (Supplychainbrain, 2013). The role of third party logistics providers is growing in India. Though there are international logistics providers like UPS and FedEx in India, their presence is limited only to large Indian cities. MNC’s have to depend on local logistics providers, who have good idea of the market landscape and also provide comprehensive services (Ups, 2003). According to Price Waterhouse Coopers, 45-55% of the costs in the supply chain stem from logistics alone (Shetty, 2015). Though the adoption of latest technology was painstakingly slow in the supply chain, of late, the integration of supply chain management software is picking up quickly. MNC’s can meet the challenges posed by the Indian supply chain provided they keep in mind that IT can be the prime enabler of the supply chain (Supplychainbrain, 2013).
  • 14. Varun Nemmani June 2016 University of Missouri- Kansas City 14 Figure 3: Indian Pharmaceutical Supply Chain (Image Source: http://www.biopharminternational.com/pharmaceutical-distribution-india ) Re-designing the supply chain: i) Designing rapid distribution channels- to meet market demands on time, to reach it with maximum efficiency and to keep the distribution costs low, MNC’s need to design distribution networks that are speedy and agile. ii) The supply chain should be capable of handling large consignments and be able to ship them to international destinations precisely. API & Raw materials supplier Manufacturer Carrying & Forwarding Agents Distribution centre Super stockists Stockists Sub-stockists Hospitals Pharmacy Retail store consumer
  • 15. Varun Nemmani June 2016 University of Missouri- Kansas City 15 iii) The firm should have control on the supply chain activities and should strive to improve transparency in the supply chain (end-to-end visibility) (Ups, 2003). iv) To introduce and implement the concept of ‘product pedigrees’ in the supply chain to make sure the pharma products are safe and viable by the time they reach the consumers. Pedigrees enable the companies to track the products anywhere in the supply chain, thereby promoting integrity of the supply chain. This will also ensure that counterfeit drugs do not enter the supply chain at any stage. An e-pedigree provides information about the drug electronically. Data about the origin of the drug, date of manufacture, expiry date, trade information of the drug all along the supply chain and the names and addresses of all the players involved in the supply chain, is revealed. it has been made mandatory by the USFDA (HIDA, 2013). v) The onus is on the manufacturer to ensure communication and collaboration between all the players in the supply chain. This would decrease the possibility of stock-outs. vi) Forecasting and planning should become a part of the supply chain activities to overcome the bull-whip effect. vii) Data and feedback should be collected from all points in the supply chain in real time (Handfield, 2005). Conclusion: The US firms wanting to expand into India should learn to play in a market that is not only fragmented but also dominated by a lot of small scale businesses that are unregulated. Also, they should learn to operate in a market where there is price ceiling imposed by the government. Despite all the challenges in the Indian pharma industry or the market, the opportunities are too good to resist. With many tax benefits, reduction of customs duties, improving infrastructure, strong support of the government and more importantly changing patent laws, the scenario of the industry seems to be brimming with positivity. All future estimates of the industry point at high growth rates and industry leaders have termed it as the future leader of the global pharma industry. There are plenty of options and companies to choose from. There are various modes of entry into the industry. The growing consumption and demand for medicines in the Indian domestic market promises a huge potential for MNC’s. The English speaking, technically skilled and low-cost workforce make India a particularly attractive destination.
  • 16. Varun Nemmani June 2016 University of Missouri- Kansas City 16 There are a lot of Indian companies facing fund crunch, stuck in huge debts, looking for expansion and modernization of their facilities and seeking to invest further in their R&D projects. Irrespective of their market size, almost all of them are seeking foreign investments in some form or the other. This in itself presents an attractive opportunity for the US pharma majors to either acquire them or strike some form of alliance with them. Many global pharma majors have realized the potential and have staked their claim of the Indian pharma pie. All in all, the future of the Indian pharma industry seems very optimistic and investment with caution would reap huge benefits.
  • 17. Varun Nemmani June 2016 University of Missouri- Kansas City 17 References: 1. Afonso, P., Dreszer, J., Francis, T., & Ramos, P. (2015). McKinsey. Retrieved 15 July, 2016, from http://www.mckinsey.com/industries/pharmaceuticals-and-medical- products/our-insights/maintaining-momentum-in-brazils-pharmaceutical-market 2. Anonymous. (2006). Pharma's Global Karma. Strategic Direction, 22(1), 5- 8. Retrieved 15 July, 2016, from doi.org/10.1108/02580540610635852 3. Business line. (2016, 6th May). The Hindu Business Line: Injecting innovation into Indian pharma. [Weblog]. Retrieved 15 July 2016, from http://search.proquest.com.proxy.library.umkc.edu/docview/1787188840?pq- origsite=summon 4. Business line. (2015, 5th June). The Hindu Business Line: Image of Indian pharma industry tarnished: EY. [Weblog]. Retrieved 15 July 2016, from http://search.proquest.com.proxy.library.umkc.edu/docview/1686129198?pq- origsite=summon&accountid=14589 5. Das, P & Das, S. (2015). Competitiveness and its impact on research and development in Indian pharmaceutical industry. Decision, 42(3), 325-334. Retrieved 18 July, 2016, from http://dx.doi.org/ 10.1007/s40622-015-0099-8 6. Economic times. (2016). The Economic Times. Retrieved 18 July, 2016, from http://economictimes.indiatimes.com/industry/healthcare/biotech/pharmaceuticals/chinas- shanghai-fosun-to-acquire-86-stake-in-gland-pharma-for-1-4- billion/articleshow/53423688.cms 7. Economic times. (2008). Economic Times. Retrieved 15 July, 2016, from http://articles.economictimes.indiatimes.com/2008-04-20/news/27709803_1_dabur- pharma-fresenius-se-fresenius-kabi-pte 8. Greene, W. (2007). US International Trade Commission. Retrieved 20 July, 2016, from https://www.usitc.gov/publications/332/EC200705A.pdf 9. Handfield, R. (2005). Supply Chain Resource Consortium. Retrieved 15 July, 2016, from http://www.supplychainredesign.com/publications/trends-pharma-biotech.pdf 10. Harding, D. (2010). Thomson Reuters. Retrieved 11 July, 2016, from http://thomsonreuters.com/content/dam/openweb/documents/pdf/pharma-life- sciences/white-paper/newport-deals.pdf
  • 18. Varun Nemmani June 2016 University of Missouri- Kansas City 18 11. HIDA. (2013). Hida. Retrieved 16 July, 2016, from http://www.hida.org/DEV/Government_Affairs/Industry_Issues/Pedigree_Supply_Chain _Integrity_/HIDA2012/HIDA/Navigation/GovernmentAffairs/IndustryIssues/PedigreeSu pplyChainIntegrity/Pedigree.aspx 12. India Brand Equity Foundation. (2016). IBEF. Retrieved 3 July, 2016, from http://www.ibef.org/industry/pharmaceutical-india.aspx 13. Indiatimes. (2016). The Times of India. Retrieved 13 July, 2016, from http://timesofindia.indiatimes.com/city/delhi/pharma-sector-to-grow-by-20-on-relaxed- fdi-norms-govt/articleshow/52898987.cms 14. Invest India. (2012). InvestIndia. Retrieved 17 July, 2016, from http://www.investindia.gov.in/pharmaceuticals-sector/ 15. Kalra, A. (2015). Reuters. Retrieved 10 July, 2016, from http://www.reuters.com/article/india-health-budget-idUSL4N0W20CA20150228 16. Kazmin, A. (2015). Financial Times. Retrieved 13 July, 2016, from http://www.ft.com/cms/s/0/e03b0f96-a638-11e5-9700-2b669a5aeb83.html 17. Kelkar, A. (2008). Bio Pharm International. Retrieved 13 July, 2016, from http://www.biopharminternational.com/pharmaceutical-distribution-india 18. Lalitha, N. (2002). Indian Pharmaceutical Industry in WTO Regime: A SWOT Analysis. Economic and Political Weekly, 37(34), 3542-3555. Retrieved 19 July, 2016, from http://www.jstor.org.proxy.library.umkc.edu/stable/pdf/4412521.pdf?_=1470123855588 19. McLain, S. (2014). WSJ. Retrieved 13 July, 2016, from http://www.wsj.com/articles/SB10001424052702303456104579487381613887674 20. Mitra, M. (2013). Economic Times. Retrieved 14 July, 2016, from http://articles.economictimes.indiatimes.com/2013-03-04/news/37437466_1_daiichi- sankyo-ranbaxy-parvinder-singh 21. Rentala, S & Anand, B. (2014). Innovation Efforts and Export Performance of Indian Pharmaceutical Industry: Empirical Evidence using Quantile Regression Approach. Bi- annual Journal of Asian School of Business Management, 7(2), 10-20. Retrieved 17 July, 2016, from
  • 19. Varun Nemmani June 2016 University of Missouri- Kansas City 19 https://ill.library.umkc.edu/illiad/illiad.dll?Action%3D10&Form%3D75&Value%3D335 072 22. Sharma, E. (2010). Business Today. Retrieved 3 July, 2016, from http://search.proquest.com.proxy.library.umkc.edu/docview/507914912?pq- origsite=summon&accountid=14589 23. Shetty, S. (2015). Pwc. Retrieved 113 July, 2016, from http://www.pwc.com/gx/en/pharma-life-sciences/pdf/global-pharma-looks-to-india.pdf 24. Singh, K. (2010). Economic Times. Retrieved 13 July, 2016, from http://articles.economictimes.indiatimes.com/2010-10-04/news/27614097_1_drugmaker- cancer-drug-drug-regulator 25. Stanton, D. (2014). In-Pharma Technologist. Retrieved 14 July, 2016, from http://www.in-pharmatechnologist.com/Processing/Fresenius-US-supply-from-troubled- Indian-plant-to-restart-in- Q3?utm_source=copyright&utm_medium=OnSite&utm_campaign=copyright 26. Supplychainbrain. (2013). Supplychainbrain. Retrieved 14 July, 2016, from http://www.supplychainbrain.com/content/world-regions/asia-pacific/single-article- page/article/indias-supply-chain-is-improving-but-still-has-a-long-way-to-go/ 27. Taylor, K. (2014, 20th January). Challenges facing India's pharmaceutical industry. [Weblog]. Retrieved 12 July 2016, from http://blogs.deloitte.co.uk/health/2014/01/challenges-facing-indias-pharmaceutical- industry.html 28. Ups. (2003). Ups. Retrieved 16 July, 2016, from https://www.ups- scs.com/solutions/white_papers/wp_outsource_biotech.pdf 29. Worldbank. (2015). Worldbank. Retrieved 11 July, 2016, from http://data.worldbank.org/indicator/SH.XPD.PUBL.ZS