4. 0
50
100
150
200
250
300
350
400
450
500
Noon 1pm 2pm 3pm 4pm
Blood Glucose (mg/dL)
Long term complications:
nerve damage, kidney failure,
blindness, amputation
Acute, short term dangers:
cognitive impairment,
seizure, coma, death
5. Precise Insulin Dosing for T1D Depends On:
Current Blood Glucose
Insulin to Carbohydrate Ratio
Carbohydrates
Insulin on Board
Protein and Fat
Insulin Sensitivity Factor
Exercise
Menstrual Cycle
Stress
Illness
and much, much more…
26. Production
Environment
Amazon Web ServicesPublic Internet
Staging
Environment
Production
Environment
Staging
Environment
Development
Environment
MongoDB Master
MongoDB Slave
MongoDB Slave
S3 Backup MongoDB Master
Production DB Cluster
Staging/Dev DB
Secure, HIPAA-compliant
Software as a Service
JavaScript
Node.js
ReactJS
D3.js
Go
MongoDB
27. Tidepool Uploader
Data Authentication and
Validation
REST APIs
Visualization
Cloud
Data
APIs
Research
APIs
EHR APIs
Messaging
and
Notification APIs
APIs enabling an Ecosystem of Research and Therapy
Research App 1 Research App 2 Athlete App Pregnancy App
Blip Nutshell Sonar AP Remote Telemetry
28. A Vibrant Ecosystem Type 1 Diabetes Application
Bolus Calculators
Remote Monitoring
Apps for Teens
Clinical Decision
Support
T1D + Fitness Data
Research Apps
and Interfaces
Apps for Pregnant
Moms with T1D
Apps for Kids
Location-aware
Apps
Contextual Meal
Memory
Psycho-social
Research
Artificial PancreasApps for Elderly
Supply
Management
T1D Triathlete
Trainer
T1D
Telemedicine
30. 2013 2014
2015 2016
Founded
Seed
Funding
Platform
Uploader
Nutshell No Clinic Left Behind
Blip Pilot
at UCSF
Blip & Uploader
Released
Blip in Clinic
Goldsmith
Foundation
Founding Team Hired
Lean Launchpad
Dex G5
Apple Health
Nutshell
Beta
Diamond StudyReplaceBG Study
+ over 30 other
clinics
FDA Quality
System Published
Glycemia Study