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VASA PREVIA
Dr.Regan,
MD
Definition
• Rupture of a fetal vessel
• Result of a velamentous insertion of the umbilical cord into the
membranes
–Veins travel across the amniotic membranes before coming
together in umbilical cord
Pathophysiology
• This is a situation where blood vessels (or their branches) in the
umbilical cord develop a route away from the cord and placenta
proper and are found just above the cervical opening
• That means they are, in effect, between the baby’s leading part
(usually the head) and the cervical opening
• Once the cervix starts dilating, the delicate vessels will be stretched
and will soon tear.
• This will unleash torrential vaginal bleeding.
Risk factors
• A low lying placenta (placenta praevia)
• Multiple pregnancy (twins or more)
• A placenta where the cord insertion is peripheral rather than central
(velamentous insertion of cord)
• IVF pregnancy: For some obscure reason, IVF pregnancy increases the
risk of vasa praevia almost 10-fold to an estimated 1 in 300.
• Previous history of uterine surgery including minor procedures such
as D&C
ALTERATIONS IN THE FETAL HEART RATE
• Initial fetal tachycardia—fetus attempts to compensate for acute
blood loss
• Bradycardia
• Intermittent accelerations
Note that;
• Fetal mortality reported to be greater than 50% Hence you must
make diagnosis rapidly and institute definitive therapy and delivery
Investigation
APT TEST
 Used to detect fetal blood.
• The blood is mixed with a small amount of tap water to cause
hemolysis.
• The sample is next centrifuged for several minutes.
• The pink hemoglobin-containing supernatant is then mixed with 1 mL
of 1% NaOH for each 5 mL of supernatant.
• The color of the fluid is assessed after 2 minutes. Fetal hemoglobin
will stay pink and adult hemoglobin will turn yellow-brown.
Management
• Consider hospitalization in the third trimester to provide proximity to
facilities for emergency cesarean delivery.
• Fetal surveillance to detect compression of vessels.
• Antenatal corticosteroids to promote lung maturity.
• Elective cesarean delivery at 35 to 36 weeks of gestation.
• Avoid amniotomy as the risk of fetal mortality is 60-70% with rupture
of the membranes
• THE END
• ANY QUESTION……..?????????

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VASA PREVIA.pptx

  • 2. Definition • Rupture of a fetal vessel • Result of a velamentous insertion of the umbilical cord into the membranes –Veins travel across the amniotic membranes before coming together in umbilical cord
  • 3. Pathophysiology • This is a situation where blood vessels (or their branches) in the umbilical cord develop a route away from the cord and placenta proper and are found just above the cervical opening • That means they are, in effect, between the baby’s leading part (usually the head) and the cervical opening • Once the cervix starts dilating, the delicate vessels will be stretched and will soon tear. • This will unleash torrential vaginal bleeding.
  • 4. Risk factors • A low lying placenta (placenta praevia) • Multiple pregnancy (twins or more) • A placenta where the cord insertion is peripheral rather than central (velamentous insertion of cord) • IVF pregnancy: For some obscure reason, IVF pregnancy increases the risk of vasa praevia almost 10-fold to an estimated 1 in 300. • Previous history of uterine surgery including minor procedures such as D&C
  • 5. ALTERATIONS IN THE FETAL HEART RATE • Initial fetal tachycardia—fetus attempts to compensate for acute blood loss • Bradycardia • Intermittent accelerations Note that; • Fetal mortality reported to be greater than 50% Hence you must make diagnosis rapidly and institute definitive therapy and delivery
  • 6. Investigation APT TEST  Used to detect fetal blood. • The blood is mixed with a small amount of tap water to cause hemolysis. • The sample is next centrifuged for several minutes. • The pink hemoglobin-containing supernatant is then mixed with 1 mL of 1% NaOH for each 5 mL of supernatant. • The color of the fluid is assessed after 2 minutes. Fetal hemoglobin will stay pink and adult hemoglobin will turn yellow-brown.
  • 7. Management • Consider hospitalization in the third trimester to provide proximity to facilities for emergency cesarean delivery. • Fetal surveillance to detect compression of vessels. • Antenatal corticosteroids to promote lung maturity. • Elective cesarean delivery at 35 to 36 weeks of gestation. • Avoid amniotomy as the risk of fetal mortality is 60-70% with rupture of the membranes
  • 8. • THE END • ANY QUESTION……..?????????