1. Study of Left Ventricular
Hypertrophy in patients with
Chronic Kidney Disease on
Maintainance Hemodialysis In
A Tertiary Care Setting
By Dr.Sharath Nallaperumal
1st Year Post-Graduate
General Medicine
2. Introduction
Left Ventricular Hypertrophy (LVH) is the most frequent cardiac alteration in
patients with Chronic Kidney Disease (CKD) undergoing hemodialysis.
In patients with CKD, LVH is a major independent risk factor for
cardiovascular morbidity and mortality
LVH results in-
- Impaired LV compliance
- Increased risk for arrythmias
- Sudden cardiac arrest
Hence, it is vital to diagnose it early in order to implement strategies to
reduce mortality
3. Aim
To study LVH in patients with CKD on maintainance hemodialysis in a teriary
care setting
Objective
To assess the prevalence of Left Ventricular Hypertrophy in patients with Chronic
Kidney Disease on maintainance hemodialysis in a tertiary care setting
4. Methodology
Study Design- A cross-sectional study of patients diagnosed with CKD who are on
maintainance hemodialysis in a tertiary care setting. Patients diagnosed with CKD
stage 5 who are on hemodialysis and who fit the inclusion criteria will be enrolled
in the study after getting their informed consent. Patient’s ECG and 2D
Echocardiogram done will be accessed to assess for findings of LVH. If not done or
if reports are not available, ECG and 2D Echocardiogram will be done afresh.
Study setting- Dialysis Unit, OPD and ICU patients of General medicine and
Nephrology department of Sree Balaji Medical College and Hospital, Chromepet
Study duration- 18 months (May 2023 to November 2024)
Sample Size- 116 (Minimum)
5. Inclusion Criteria
• Adult male and female patients (aged>/=18years) diagnosed with CKD Stage 5
[eGFR<15 ml/min/1.73 m2] who are on maintainance hemodialysis
Exclusion Criteria
• Patients with CKD below the age of 18 years
• Patients with CKD Stages 1-4 who are not on hemodialysis
• Patients who undergo emergency hemodialysis (Newly diagnosed CKD)
6. Study Tools
Patient’s ECG and 2D Echo reports - if not done, to be done afresh
Patient’s RFT and other laboratory reports (if relevant)
MS Office- Excel worksheet to analyse data set
