The document discusses several topics related to healthcare of the future: 1) The world's population is projected to reach 9.7 billion by 2050, increasing demands on healthcare systems. 2) Life expectancy has been rising in the UK, but chronic conditions and mental health issues affect a large portion of the population. 3) New advanced therapies using gene-modified cells show promise for treating cancers like leukemia. 4) Age-related macular degeneration is a major cause of vision loss that treatments using stem cell-derived patches could help address.

1. Healthcare of the Future
Dr Ruth McKernan CBE - Chief Execu5ve
@RuthMcKernan

2. The world’s popula4on is projected to reach 9.7 billion by 2050
Data courtesy of the Office for Na5onal Sta5s5cs and the United Na5ons
84
86
88
90
92
94
96
98
1980 1990 2000 2010 2020 2030 2040
Life expectancy at birth
UK females
UK males

3. Liver disease
6% Respiratory
disease
9%
Other diseases
21%
Cardiovascular
disease
22%
Cancer
42%
Lead causes of
premature death in
England
Data courtesy of NHS England

4. Data courtesy of the Department of Health and the King’s Fund
30%
of the popula5on of
England have at least
one long-term condi5on
30%
of that group have
a mental health
condi5on

9. Harvest
T cells from
patient
Anti-tumour
activityT cell
receptor
therapy
Genetically
engineer cells
Infuse back
into patient
Trea4ng cancer with new advanced therapies
Advanced therapies are being developed using gene-
modified T cells targe5ng the WT1 gene that is expressed in
blood cancers such as acute myeloid leukaemia (AML).
Content courtesy of

10. Age-related Macular Degenera4on
Images courtesy of the London Project to Cure Blindness, UCL, Neusen5s/Pfizer, Moorfields Eye Hospital
§ Major cause of vision loss
over age of 65
§ 600,000 cases in the UK
§ Expected to rise to 700,000
cases by 2020
§ Cases may double by 2030

11. RPE patch made from stem cells ready for human treatment
Images courtesy of the London Project to Cure Blindness, UCL, Neusen5s/Pfizer, Moorfields Eye Hospital

12. Working with the research community and across Government to turn scien5fic
excellence into economic impact
Accelera4ng UK economic growth, nurturing small, high-growth companies, with
strong produc5vity and export success
Building on innova4on excellence throughout the UK, inves5ng locally in areas
of strength
Developing Catapults within a na4onal innova4on network
Evolving our funding models; helping public funding go further
Our 5-point plan

13. The Catapults
Network

14. Innovate UK supports UK businesses across sectors

16. Meet the innovators

17. We can’t stop
thinking about
the future
Dr Ruth McKernan CBE
@RuthMcKernan
www.innovateuk.gov.uk