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ALZHEIMER’S DISEASE:
MANAGEMENT CHALLENGES
& TREATMENT MEASURES
RICCI M. HAYES
JUNE 7, 2015
HCM310 – Introduction to the U.S. Healthcare System
Colorado State University – Global Campus
Dr. Dawn Tesner
Alzheimer’s Disease (AD): The Numbers
AD afflicts 5.2 million people and is
expected to reach as much as 16
million by 2050 (Medscape, 2015a).
Americans spend roughly
$100,000,000 per year on AD
care, a figure expected to rise
exponentially (de la Torre, 2010).
Source: http://reference.medscape.com/features/slideshow/alzheimers/
80-90% of nursing home patients
with dementia have
neuropsychiatric symptoms, a
precursor to staff turnover, stress,
and burnout (Van de Ven, Draskovic, Van
Herpen, Koopmans, Donders, Zuidema,
Adang, Vernooij-Dassen , 2014).
Incidence of AD vs other chronic disease
Aging-related Alzheimer’s Disease
increasingly evident until ~ 90
years old
Other co-morbidities such as
diabetes and arthritis, start to
decline ~ 70-80 years old.
(Akushevich, Kravchenko, Ukraintseva,
Arbeev, &Yashin, 2012).
Source: Akushevich, et al, 2012, p. 325
AD in Skilled Nursing Facilities (SNFs)
 Many AD afflicted are in SNFs. This is covered
by Medicare, right?
 Not exactly…
 Days 1-20, paid in full
 Days 21-100, Medicare Part A pays primary,
patient pays co-pay
 Day 101…no Medicare reimbursement
(Center for Medicare & Medicaid Services, 2014)
Affordable Care Act (ACA) and AD
 ACA includes mandate: improve transparency
about ownership of SNFs (Sultz & Young, 2014).
 ACA through CMS provides patient
information about “grades” of SNFs relative to:
 Health Inspection
 Staffing
 Quality Measures (Medicare, 2015)
AD Treatment & Cost Containment
 Are there treatment options that reduce cost of
long-term care?
 Van de Ven, et al, (2014) previously studied
dementia-care mapping (DCM) and showed
effective in dementia care, but sought to
examine further…
Is the one-to-one treatment cost efficient
for SNFs?
AD Treatment & Cost Containment (cont.)
“We find that DCM is a cost-neutral intervention
for nursing home residents with dementia that
has an advantage over usual care when it
comes to the costs of outpatient hospital
appointments. Since DCM has shown positive
effects on resident outcome measures such as
depression, agitation and quality of life,
considerations other than costs may
determine whether or not a nursing home will
adopt this method,” (Van de Ven, et al, 2014, p.8, para.2)
Prevention=Cost Savings Champion
There is no cure for Alzheimer’s.
Early prevention of known risk
factors, may delay, or even
eliminate the causation of AD.
Author states that “carotid artery
ultrasound and echocardiography
together with ankle-brachial index…
[are] cost-effective, non-invasive,
and reasonably accurate” in
detecting risks for AD (de la Torre,
2010, p.868, para.5).
Source: de la Torre. (2010). p.865
Prevention=Cost Savings Champion
In Medscape’s etiology section on AD, it says:
Midlife hypertension is an established risk factor for
late-life dementia, of which AD is the most common
type. A brain autopsy study evaluating the link
between hypertension and AD found that patients
using beta-blockers to control blood pressure had
fewer Alzheimer's-type brain lesions on autopsy
compared to patients taking no drug therapy or those
taking other medications (2015b).
Alzheimer’s Disease Management
AD is a debilitating, progressive disease.
AD care costs Americans millions of dollars.
AD has no cure.
Only by addressing the lifestyle, preventable
risks of AD, can we hope to curb the
increasing rate of disease and its associated
financial burden to American healthcare.
References
 Akushevich, I., Kravchenko, J., Ukraintseva, S., Arbeev, K., Yashin, A. (2012, February). Age patterns of
incidence of geriatric disease in the U.S. elderly population: Medicare-based analysis. Journal of the
American Geriatrics Society, 60(2), 323-327. doi: 10.1111/j.1532-5415.2011.03786.x
 Center for Medicare and Medicaid Services. (2014, August). Skilled nursing facility (SNF) billing reference.
Retrieved from http://www.cms.gov/Outreach-and-Education/Medicare-Learning-Network-
MLN/MLNProducts/downloads/SNFSpellIllnesschrt.pdf
 de la Torre, J. (2010, July 1). Alzheimer’s disease is incurable but preventable. Journal of Alzheimer’s Disease,
20(3), 861-870. doi: 10.3233/JAD-2010-091579
 Medicare. (2015). Nursing home compare. Retrieved from
http://www.medicare.gov/NursingHomeCompare/compare.html#cmprTab=0&cmprID=555161%2C05615
3%2C555639&cmprDist=0.7%2C1.0%2C3.6&loc=94558&lat=38.3170536&lng=-122.3019206
 Medscape. (2015a). Alzheimer’s disease: Slideshow. Retrieved from
http://reference.medscape.com/features/slideshow/alzheimers/
 Medscape. (2015b). Alzheimer disease: Etiology. Retrieved from
http://emedicine.medscape.com/article/1134817- overview#aw2aab6b2b5
 Sultz, H. & Young, K. (2014). Health care USA: Understanding its organization and delivery (8th edition).
Burlington, MA: Jones & Bartlett Learning, LLC.
 Van de Ven, G., Draskovic, I., Van Herpen, E., Koopmans, R., Donders, R., Zuidema, S., Adang, E., Vernooij-
Dassen, M. (2014, January). The economics of dementia-care mapping in nursing homes: A cluster-
randomised controlled trial. Plos One, 9(1), 1-8. doi: 10.1371/journal.pone.0086662

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Alzheimer’s Disease

  • 1. ALZHEIMER’S DISEASE: MANAGEMENT CHALLENGES & TREATMENT MEASURES RICCI M. HAYES JUNE 7, 2015 HCM310 – Introduction to the U.S. Healthcare System Colorado State University – Global Campus Dr. Dawn Tesner
  • 2. Alzheimer’s Disease (AD): The Numbers AD afflicts 5.2 million people and is expected to reach as much as 16 million by 2050 (Medscape, 2015a). Americans spend roughly $100,000,000 per year on AD care, a figure expected to rise exponentially (de la Torre, 2010). Source: http://reference.medscape.com/features/slideshow/alzheimers/ 80-90% of nursing home patients with dementia have neuropsychiatric symptoms, a precursor to staff turnover, stress, and burnout (Van de Ven, Draskovic, Van Herpen, Koopmans, Donders, Zuidema, Adang, Vernooij-Dassen , 2014).
  • 3. Incidence of AD vs other chronic disease Aging-related Alzheimer’s Disease increasingly evident until ~ 90 years old Other co-morbidities such as diabetes and arthritis, start to decline ~ 70-80 years old. (Akushevich, Kravchenko, Ukraintseva, Arbeev, &Yashin, 2012). Source: Akushevich, et al, 2012, p. 325
  • 4. AD in Skilled Nursing Facilities (SNFs)  Many AD afflicted are in SNFs. This is covered by Medicare, right?  Not exactly…  Days 1-20, paid in full  Days 21-100, Medicare Part A pays primary, patient pays co-pay  Day 101…no Medicare reimbursement (Center for Medicare & Medicaid Services, 2014)
  • 5. Affordable Care Act (ACA) and AD  ACA includes mandate: improve transparency about ownership of SNFs (Sultz & Young, 2014).  ACA through CMS provides patient information about “grades” of SNFs relative to:  Health Inspection  Staffing  Quality Measures (Medicare, 2015)
  • 6. AD Treatment & Cost Containment  Are there treatment options that reduce cost of long-term care?  Van de Ven, et al, (2014) previously studied dementia-care mapping (DCM) and showed effective in dementia care, but sought to examine further… Is the one-to-one treatment cost efficient for SNFs?
  • 7. AD Treatment & Cost Containment (cont.) “We find that DCM is a cost-neutral intervention for nursing home residents with dementia that has an advantage over usual care when it comes to the costs of outpatient hospital appointments. Since DCM has shown positive effects on resident outcome measures such as depression, agitation and quality of life, considerations other than costs may determine whether or not a nursing home will adopt this method,” (Van de Ven, et al, 2014, p.8, para.2)
  • 8. Prevention=Cost Savings Champion There is no cure for Alzheimer’s. Early prevention of known risk factors, may delay, or even eliminate the causation of AD. Author states that “carotid artery ultrasound and echocardiography together with ankle-brachial index… [are] cost-effective, non-invasive, and reasonably accurate” in detecting risks for AD (de la Torre, 2010, p.868, para.5). Source: de la Torre. (2010). p.865
  • 9. Prevention=Cost Savings Champion In Medscape’s etiology section on AD, it says: Midlife hypertension is an established risk factor for late-life dementia, of which AD is the most common type. A brain autopsy study evaluating the link between hypertension and AD found that patients using beta-blockers to control blood pressure had fewer Alzheimer's-type brain lesions on autopsy compared to patients taking no drug therapy or those taking other medications (2015b).
  • 10. Alzheimer’s Disease Management AD is a debilitating, progressive disease. AD care costs Americans millions of dollars. AD has no cure. Only by addressing the lifestyle, preventable risks of AD, can we hope to curb the increasing rate of disease and its associated financial burden to American healthcare.
  • 11. References  Akushevich, I., Kravchenko, J., Ukraintseva, S., Arbeev, K., Yashin, A. (2012, February). Age patterns of incidence of geriatric disease in the U.S. elderly population: Medicare-based analysis. Journal of the American Geriatrics Society, 60(2), 323-327. doi: 10.1111/j.1532-5415.2011.03786.x  Center for Medicare and Medicaid Services. (2014, August). Skilled nursing facility (SNF) billing reference. Retrieved from http://www.cms.gov/Outreach-and-Education/Medicare-Learning-Network- MLN/MLNProducts/downloads/SNFSpellIllnesschrt.pdf  de la Torre, J. (2010, July 1). Alzheimer’s disease is incurable but preventable. Journal of Alzheimer’s Disease, 20(3), 861-870. doi: 10.3233/JAD-2010-091579  Medicare. (2015). Nursing home compare. Retrieved from http://www.medicare.gov/NursingHomeCompare/compare.html#cmprTab=0&cmprID=555161%2C05615 3%2C555639&cmprDist=0.7%2C1.0%2C3.6&loc=94558&lat=38.3170536&lng=-122.3019206  Medscape. (2015a). Alzheimer’s disease: Slideshow. Retrieved from http://reference.medscape.com/features/slideshow/alzheimers/  Medscape. (2015b). Alzheimer disease: Etiology. Retrieved from http://emedicine.medscape.com/article/1134817- overview#aw2aab6b2b5  Sultz, H. & Young, K. (2014). Health care USA: Understanding its organization and delivery (8th edition). Burlington, MA: Jones & Bartlett Learning, LLC.  Van de Ven, G., Draskovic, I., Van Herpen, E., Koopmans, R., Donders, R., Zuidema, S., Adang, E., Vernooij- Dassen, M. (2014, January). The economics of dementia-care mapping in nursing homes: A cluster- randomised controlled trial. Plos One, 9(1), 1-8. doi: 10.1371/journal.pone.0086662

Editor's Notes

  1. Comparison between healthy brain and one with AD shows the death of brain tissue. Critics of AD “treatment” say that even if you could re-grow neuropathways, they would not be that of the original being and are therefore, unethical (Akushevich, Kravchenko, Ukraintseva, Arbeev, Yashin, 2012).
  2. Study from authors of Medicare data reviewing 26% of the U.S. population to evaluate the incidence of AD among population over 70 years of age. Interestingly, while AD incidence climbs to age 90-95, incidence of other chronic disease declines with age, making AD a greater concern for long term care facilities (LTCF).
  3. Other provisions are supported by Affordable Care Act including respite care and in-home services (Sultz & Young, 2014). But for SNFs, billing management is imperative. AD afflicted will not be “cured” in 100 days.
  4. I was surprised to find the ‘Nursing Home Compare’ link on CMS website. In the reference provided you will find three clinics with which I have regular contact. My assumption was that Meadows, a non-profit SNF would receive the top ranking; I was off-base.
  5. Netherlands study involving 318 residents and 376 staff members. The question arose from their previous study; it’s one thing to identify effective measures in AD management, but quite another to consider whether treatments are indicated and efficient.
  6. The study indicated that although no ‘savings’ were identified in the increased staff attention, neither were additional expenses identified; there were secondary cost savings, such as those with outpatient hospital appointments, needs for which were reduced.
  7. Author is critical of “treatments” for AD suggesting that medications for removing plaques from what are really dead brain neurotransmitters, is like digging up graves and expecting people to rise from the dead. Prevention may not only be most effective for AD, but come at a great cost savings for future generations.
  8. This information further illustrates a link between preventing risk factors and preventing AD.
  9. Risks for AD are preventable, and should be addressed with those not yet showing symptoms according to de la Torre, 2010.