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MAXILLARY SINUS:
Contents
1. Introduction
2. Embryology of maxillary sinus
3. Anatomy of maxillary sinus
4. Microscopic anatomy
5. Drainage of sinus
6. Functions of sinus
7. Classification of diseases of maxillary sinus
8. Maxillary sinusitis
9. Oroantral fistula
10. Benign and malignant tumors of maxillary sinus
11. Approaches to maxillary sinus
12. Conclusion
13. References
Introduction:
Maxillary sinus
 Pneumatic space lodged in the body of
maxilla that communicates with the
external environment by way of middle
meatus and nasal vestibule - by Orban’s
 Also known as antrum of Highmore (1651)
Embryology
• Development of sinus begins as
evagination of mucus membrane in
lateral wall of middle meatus when
nasal epithelium invades maxillary
mesenchyme ( Kitamura, 1989)
• Growth of sinus takes place by
pneumatization
 Primary (10th weeks)
 Secondary (5th month)
• Post natally grows @ 2 mm vertically and 3 mm AP
• 3 growth spurts
a) 0-2.5 years
b) 7.5-10 years
c) 12-14 years
Growth:
Anatomy:
 Base-Lateral wall of nose
 Apex – projects laterally into zygomatic process
of maxilla
 Roof – orbital floor
 Floor – alveolar process of maxilla which
supports premolars and molars
 Posterior wall – infra-temporal and pterygo-
palatine fossa
 Anterior wall – facial surface of maxilla
Medial wall
IMP STRUCTURES:  Sinus ostrium
 Hiatus semilunaris
 Ethmoidal bulla
 Uncinate process
 Infundibulum
Natural ostium
• Located in posterior ½ of
infundibulum or behind
lower1/3 of uncinate
process.
• Tunnel shaped, length: 1-
22mm;3-6mm diameter
• Unfavorable position for
gravity dependent drainage
• Post edge-continuous with
lamina papyracea(imp for
surgical dissection)
Superior wall
• Forms roof of sinus and floor of orbit
• Imp structures
• Infra orbital canal
• Infra orbital foramen
• ASA nerve
• Applied aspect
Posterolateral wall
 Made of zygomatic and greater wing of sphenoid bone(maxillary
tuberosity)
 Imp structures
 PSA nerve
 Maxillary artery
 Maxillary nerve
 Pterygopalatine ganglion
 Nerve of pterygoid canal
Anterior wall
• Extends from pyriform
aperture anteriorly to ZM
suture
& IO rim superiorly to alveolar
process inferiorly.
• Imp structures
 Infraorbital foramen
 ASA, MSA nerves
 Levator labii, obicularis
oculi muscles
Floor of sinus
• Formed by junction of anterior sinus wall
and lateral nasal wall
• 1-1.2 cm below nasal floor
Vascularization & innervation
Arterial Supply
a) Nasal MucosalVasculature
SP, Ethmoid
b) OsseousVasculature
IO, PSA,ASA,GP, Facial
Venous Drainage
a) Medial wall - SP
b) Other walls – Pterygomaxillary
Plexus
Lymphatic Drainage Collecting vessels in middle meatus
Nerve Innervation ION, GP, PSA, MSA, ASA
Microscopic anatomy
• 3 layers
 Epithelium
 Basal lamina
 Sub epithelium
Pseudo stratified columnar
ciliated epithelium
• Cells
 Columnar ciliated
 Goblet
 Basal
 Non – ciliated
Drainage of sinus
Mucociliary flow from anterior sinuses converge at OMC, carried to posterior
nasopharynx & inferiorly to eustachian tube orifice
Mucus coursing along lateral wall, carried medially along roof to reach ostium
Drainage into ethmoidal infundibulum
Upward course along walls of entire cavity and then towards natural ostium in
superomedial wall
Flow of mucus superiorly against gravity
By Donald et al & Antunes et al
Drainage of sinus
Functions of sinus
1. Decrease skull weight
2. Impart resonance to voice
3. Mucus production and storage
4. Humidify and warm inhaled air
5. Define facial contour
6. Immunodefensive action
7. Conserve heat from nasal fossae
8. Moisturize air
9. Filters debris
10. Dampen pressure differential during inspiration
11. Limit extent of facial injury from trauma
12. Serves as accessory olfactory organ
Classification of diseases
 Maxillary sinusitis :Inflammatory
 odontogenic
 Oro antral fistula :acute and chronic
 Traumatic: hematoma in sinus
 Iatrogenic: tooth or root displaced into sinus
 Cysts of the maxillary sinus
 Intrinsic origin-
 Mucocele
 Serous cyst
 Choleosteatoma
 Extrinsic origin
 OKC
 Radicular cyst
 Tumors:
 1.Benign tumors
 Intrinsic origin-
 Papilloma
 Juvenile angio fibroma
 Extrinsic origin
 Ameloblastoma
 Odontoma
 CEOT
 2.Malignant tumors: carcinoma of maxillary sinus
 Tumor like lesions
 Fibrous dysplasia
 Ossyifying fibroma
 Antral rhinoliths
Maxillary sinusitis
Maxillary sinusitis
Maxillary sinusitis
1. Infectious causes
a) Bacterial
b)Viral
c) Fungal
d) Parasitic
2. Non infectious causes
a)Allergic
b) Non allergic
c) Pharmocologic
d) Irritants
3. Disruption of
mucociliary drainage
a) Surgery
b) Infection
c)Trauma
Extrinsic
causes 1. Genetic
a) Structural
b) Immunodeficiency
c) Mucociliary abnormality
(cystic fibrosis, dismotility)
2. Acquired
a) Aspirin hypersensitivity
b)Autonomic
dysregulation
c) Hormonal
d) Structural (Tumors,
cysts)
e)Idiopathic/ autoimmune
f) Immunodeficiency
Intrinsic
causes
Acute maxillary sinusitis :haemophilus influenzae, streptococcus pneumoniae, or
maraxella catarrhalis.
chronic sinusitis : anaerobic and polymicrobial and more likely to involve
staphylococcus aureus.
odontogenic etiology related with first molar infection with mucostasis of other cause.
ETIOLOGY OF MAXILLARY
SINUSITIS:
DIAGNOSIS:
SYMPTOMS:: maxillary pain, pressure, pain similar to toothache,
CLINICAL FINDINGS: fever, throat-clearing cough, purulent
rhinorrhea, hyposmia, headache, malaise, maxillary anterior wall
tenderness to percussion, purulence noted, in cases associated with
cellulitis ,facial swelling and erythema seen ,
RADIOGRAPH: —water’s view, fluid opacification of maxillary sinus
CT SCAN
SIGNS AND SYMPTOMS OF ACUTE MAXILLARY
SINUSITIS
SIGNS:
 Pain on pressure over the anterior maxillary sinus wall.
 Purulent discharge over the inferior nasal turbinate.
 Fever
 Malaise
SYMPTOMS
 Cheek pain with referral to frontal region.
 Increased pain on bending.
 Maxillary posterior teeth free like “pegs”
 Hyposmia
MELENS CRITERIA FOR CHRONIC SINUSITIS :
 Facial pain, nasal congestion or abnormal
secretions remain or reappear during a period of
at least 3 months.
 Sinus radiography or sinus endoscopy reveals
persistent localized or generalized mucosal
swelling with or without secretions.
 Chronic maxillary sinusitis of rhinogenous origin
that does not heal after conservative treatment.
 Chronic maxillary sinusitis of dental origin.
Maxillary sinusitis
 Diagnosis
1. History
2. Physical examination
 Inspection
 Palpation
 Percussion
 Diagnostic techniques
a. Rhinoscopy
b. Endoscopy
c. Culture and sensitivity
Maxillary sinusitis
3. Radiological examination
a) Lateral view
b) CT scan
c) MRI
4. Tests for mucociliary functions
a) Naso mucociliary clearance
b) Ciliary beat frequency
c) Rhino manometry
5. Test for olfaction
Maxillary sinusitis
Management
Medical
1. Antibiotics
2. Steroids
3. Decongestants
4. Analgesics
5. Antihistamines
6. Nasal spray & saline irrigation
7. Hydration
8. Mucolytics
Surgical
1. sinus aspiration and lavage
2. Maxillary needle sinusotomy
3. Caldwell luc
4. FESS
Antibiotics
Antibiotic Micro factors
FIRST LINETHERAPY
Amoxicillin 45 mg/kg/day or 90 mg/kg/day divided
Amoxicillin/potassium calvulanate
22.5-45 mg/kg/day divided (dose based on
amoxicillin component)
Azithromycin
10 mg/kg/day on day 1, then 5 mg/kg/day on days 2-
5
Cefdinir 14 mg/kg/day
Cefpodoxime 10 mg/kg/QID
Cefprozil 15 mg/kg/QID
Cefuroxime 15 mg/kg/QID
Ciprofloxacin
Clarithromycin 7.5 mg/kg/day
Cindamycin 8-20 mg/kg/day dividedQID
Doxycycline
Garifloxacin
Levofloxacin
Sulfamethoxazole/trimethoprim 6-12 mg/kg/day divided (based on trimethoprim)
1.Steroids:
• 1st line of therapy: topical intranasal (beta methasone, dexa methasone,
triamcinolone)
• Systemic steroids:
• Prednisolone:0.5-1mg/kg x3-4 days
2.Decongestants:
Systemic (phenyl propanolamine, pseud oephidrine):
• Contraindications: hypertension, hyperthyroidism, asthma
Topical: pheny lepinephrine HCl, oxy metazoline HCl
• Adv. Effects- rhinitis medicamentosa
3.Analgesics:
• Opioid: acetaminophen, codeine
• NSAIDS:
4.Antihistamines:
• Mequitazine, terfenad
• Contraindicated in bacterial sinusitis
• Adv effect: sedation
Nasal lavage & sprays
• Removes debris & dead tissue
• Washes inflammatory secretions
• Eliminates nutrient source
• Methods:
• Lavage pot
• Syringe
• Irrigating bulb
Surgical management
Indications
• Bilateral chronic
sinusitis with polyps
• Fungal sinusitis
• Presence of
complications
• Tumor of PNS
• CSF rhinorrhea
Contraindications
• Presence of
extensive polyps
• Pt with complaint of
headache and mid
facial pain
• Medically
compromised
• Hypo plastic sinuses
Sinus aspiration & lavage
 Direct removal of bacteria laden secretions
 Indication: no response to medical therapy
Maxillary needle sinusotomy
• Complications:
• Bleeding
• Infection
• Dental injury
• Sensory nerve disturbance
• Instrument breakage
Infiltration of LA
Preparation of site
Transcutaneous
puncture ant & post to
canine eminence
Caldwell luc sinusotomy
 By George Caldwell (1893) & Henry Luc (1897)
 Indications
 Fungal sinusitis
 Multiple antral lesions
 Antrochoanal polyp
 Excision of tumor
 Closure of OAF
 Removal of antral foreign body
 surgical approach for transantral spheno ethmoidectomy,
orbital decompression
Caldwell luc sinusotomy
Complications
•Bleeding
•Dental sensitivity
•Infraorbital neuralgia
•Osseous defect in
anterolateral wall
•Entrapment of inferior
rectus muscle
FESS
 Coined by Kennedy
 Principle: stop the cycle that
begins with ostium blockage
that leads to chronic sinusitis
via stagnated secretions,
tissue inflammation and
bacterial infections.
FESS
FESS
FESS
Minor hemorrhage
Hyposmia
Adhesions
Periorbital emphysema
Intracranial hemorrhage
Brain injury
CSF leak
Diplopia
Blindness
Anosmia
Epistaxis
NL duct injury
Meningitis
Complications
Complications of untreated maxillary
sinusitis:
 Complications:
 Facial cellulitis
 Orbital extension
 Intracranial
extension
DISPLACED ROOT OR TOOTH INTO THE
SINUS
 Most common complication following tooth extraction.
 Roots are those of the 1st molar (80%) with slightly less
than 20 % are 2nd molar and the remainder involving the
3rd molar and 2nd premolar and rarely the canines
Procedure to retrieve broken root tip from
antrum:
 Place the pt in upright position
Determine the location of tooth /root tip
Determine antral perforation/IOPA has
to be taken
If it in the sinus
Place small suction tip in to sinus
through the socket gently/saline
irrigation can be done
Pack 0.5inch long
iodoform gauge in to the
sinus &pull it out in one
stretch
Cald well luc sinusotomy
SINUS EXPOSURE FOLLOWING TUBEROSITY
FRACTURE
 Prevented by preliminary expansion of the socket
 In multiple extractions 3 rd molar should be extracted 1 st
 Discontinue the extraction
 Fixation is done by an arch bar, acrylic splint or an
orthdontic appliance
ORO ANTRAL FISTULA
OROANTRAL FISTULA
 Etiology
• Iatrogenic (50%)
• Presence of periapical lesions
• Injudicious use of instruments
• During attempted extraction
• Trauma(7.5%)
• Chronic infections(11%)
• Malignant diseases(18.5%)
• Infected maxillary dentures(3.7%)
• h/o sinus surgery(7.5%)
Predisposing factors
Acute Chronic
1. Escape of air and fluids through nose &
mouth
1.Pain, tenderness over cheeks which is
dull and boring type
2. Epistaxis 2. Purulent discharge
3. Excruciating pain 3. Post nasal drip
4. Altered voice due to enhanced column
of air
4. Presence of polyps
5. h/o surgery in vicinity of sinus, escape
of fluids in to the nose
5. Generalized constitutional symptoms
Signs & symptoms of
oroantral fistula
Diagnosis
H/o previous extraction
Mouth mirror test
Nose blow test
Cotton wisp test
Inspection
Radiological
 IOPA
 OPG
MANAGEMENT
• 3mm-5mm heals spontaneously
• Acute OAF: closure by simple reduction of buccal and
palatal socket walls, followed by acrylic splint.
1) Antibiotics : Penicillin & derivatives
2) Nasal decongestants:
 Ephedrine drops
 Inhalations(steam , benzoin ,menthol)
3) Analgesics:
 Aspirin 500mg
 Paracetamol 500mg
 Ibuprofen 400 mg
4) Antral lavage
Surgical management:
Closure of Oroantral Communications:A Review of the Literature, Susan H. Visscher et al, J Oral Maxillofac
Surg68:1384-1391, 2010
•Temporalis
flap
•Forehead
flap
Overview of the treatment modalities of Oro-Antral Communications
Surgical closure
• Factors determining flap selection
• Size of communication
• Timeline of diagnosing
• Presence of infection
Buccal flap:
The defects can be closed by
a. Advancement flaps
b. Sliding flaps
Buccal advancement flap
Adv:
 Broad base
 No denuded area
Disad:
Depth of buccal vestibule
obliterated
Buccal sliding flap
 Moczair described it
 Minimal change in
buccal vestibule
 Facilitates distal shift
of flap
 Disad:
 Raw surface anteriorly
 Gingival recession
Modified BuccalAdvancement Flap
Laskin and Robinson
described it first
A clinical study on oro antral fistula;
J cranio maxillofacial
surg.1998;26;267-71
Palatal Flaps:
These includes
a. Straight advancement
b. Rotational advancement
c. Island palatal flap
d. Hinged palatal flap
StraightAdvancement Flap:
RotationalAdvancement Flap:
Ø Kruger suggested V-
shaped excision of tissue on
the lesser curvature to
minimize folding the flap.
Sub mucosal Connective Tissue Flap:
Ito and Hara described elevation
of full-thickness palatal flap
followed by creation of a
submucosal connective tissue
flap to close the fistula and
return of the remainder of the
flap to lower the original donor
site.
Island Palatal Flap:
Hendersen has described the use of a
palatal pedicle island flap.
Because of the mobility of this flap
and its excellent blood supply it
can be used to close larger defect.
James suggested that sectioning the
island should be done best so
that the tissue can still be used as
a rotational advancement flap or
rotational to tits original site will
cause injury to its vessels.
Hinged Flap:
The mucoperiosteum on the
palatal aspect of the
oroantral fistula can be used
as a hinged flap to close
small opening.
Combined Local Flaps:
They are
Simple
Transverse
Bipedicled
Buccopalatal flap
These are practiced where there
is sufficient large edentulous
surface.
Combination of inversion and
rotational advancement
flaps.
Double hinged flaps.
Double island flaps.
Superimposed reverse palatal
buccal flaps.
Distant Flaps
1. Flap from extremities
2. Flap from forehead
3. Tongue flap
4. Temporalis flap
5. Buccal fat pad flap
BUCCAL FAT PAD
Use of pedicled buccal fat pad in closure of oro antral communication;
analysis of 75 cases
Dolanmaz et.al.,
Quintessence international 2004: 35(3) ; 241-426
TONGUE FLAP
Introduced by lexer,1909
Technique
Advantages
Disadvantages
Use of the tongue flap for intra oral
reconstruction; report of 16 case
Kim, Yeo and Kim
J Oral Maxillofac Surg 1998; 56: 716-719
TEMPORALIS FLAP:
 Advantages:
Proximity to the oral cavity.
Safety of it vascular pedicle.
Its pliability
Minimal functional and esthetic sequelae
Less dysfunction during healing.
 Procedure:
GRAFTS
Grafts
GRAFTS
AUTOGENOUS
Iliac crest
Chin
Retromolar area
Zygoma
Brusati has used
bone from lateral
wall
ALLOGENOUS
Collagen sheet
Fibrin glue
Gold foil
Tantalum
PMMA
Hydroxyapatite
XENOGRAFTS
Porcine dermis
Bio guide & Bio oss
Other techniques
• Third molar transplantation(kitagawa et al)
• Interseptal alveolotomy(hori et al)
• GTR(Waldrop & Semba)
• Prolamine gel(Gotzfried & Kaduk)
• Laser light(Janas)
• Splints for immunocompromised pts(llogan and coates)
• Allotransplants of fasvia lata and dura
matter(guven;1995)
• Buccinator myo mucosal island flap(J.OralMaxillofacial
Surg;2002;60;816-821)
THE EFFECTS OF TRAUMAON
THE MAXILLARY SINUS
The effects of traumatic sinus
disruption vary from:
-Chronic sinusitis
-Polyps
-Mucocele formation
-Acute sinusitis with extension to
more vital organs
 Any midfacial trauma --clouding of the sinus
 ZMC fracture involves inferior orbital fissure --orbital
floor is often comminuted creating multiple fracture lines
in roof of the maxillary sinus
 Fractures of the internal orbit --teardrop radioopacity
 Lefort fractures --involve maxillary sinus
Response of maxillary sinus to trauma
a)Mucosal regeneration
b)Bony regeneration
Management:
 Generally does not require direct treatment
 The sinus regenerates after the hemorrhagic fluids have
been removed by mucociliary action
 Gross debris must be removed before closing the soft
tissues overlying it
Reconstruction of sinus walls:
 Common area is roof of sinus (floor of the orbit)
 Indications: enoptholmos, exopthalmos, diplopia, isolated
sinus wall defects
Autogenous
 Eg: calvarial, iliac crest
Nonautogenous
 Eg: lyophilized dura, siloxane, teflon and other
bioresorbable materials,grafts
INFECTIOUS DISEASES OF THE
MAXILLARY SINUS
 Aspergillosis :
Caused by the fungus aspergillus
Immune compromise is common
Severe neutropenia
H/O recent treatment with cytotoxic drugs &
corticosteroids
 Aspergillosis :
Thick ,dark greasy material is found in the sinus
 Three types are seen:
Non invasive
Invasive
Fulminant
Treatment includes aggressive debridement &
systemic antifungal therapy
 Mucormycosis :
Caused by fungi of the class phycomycetes
Infection is usually fatal
Impaired chemotaxis & phagocytic activity
Virulent strain can cause thrombosis ,ischaemia &
necrosis
 Clinical signs of advanced disease are:
 Proptosis
 Opthalmoplegia
 Anesthesia of trigeminal nerve distribution
 Cavernous sinus thrombosis
 Facial palsy
Management includes
 Correction of the underlying metabolic/hematologic
abnormality
 Aggressive debridement & Systemic antifungal
therapy
Maxillary antrolithiasis:
 Asymptomatic or pain,
nasal obstruction,
epistaxis, sinusitis.
 Investigation:
 Radiographs – opaque
mass
 Treatment – surgical
removal
BENIGN MUCOSAL CYST
• Most common cyst
• Due to obstruction of the glandular ducts.
Clinical features:
1. Discomfort in the cheek or maxilla.
2. Buccal expansion of the antrum.
3. Nasal obstruction.
4. Post nasal discharge.
5. External deformity of the face.
Radiographic features: appear as rounded lightly
opaque shadow in the floor of the sinus.
Aspiration: through inferior turbinate will reveal straw or
amber-coloured fluid “cholesterol crystals”.
Treatment:
Asymptomatic: monitor
1. Cannulation through inferior turbinate puncture.
2. Marsupialization
3. Enculeation through cald well. Luc operation with
nasal antrostomy.
Odontogenic keratocyst:
 Maxillary OKC’S occur primarily in the 3 rd molar
region with canine being the 2 nd most common site
 Peak incidence is in 2 nd & 3 rd decades
TUMOURS OF THE MAXILLARY SINUS
 Ameloblastoma
 Antrum & nasal floor are common sites
Most cases arise extrinsic to the sinus
Present as an enlarging mass
 Management : en bloc excision with good
surgical margins
CALCIFYING EPITHELIAL
ODONTOGENIC TUMOUR
 Arises from the epithelial remnants of the enamel
organ
 Comprises 1% of all odontogenic tumours
 Slow growing painless swelling
 Age :40 years approximately
CEOT
 MANAGEMENT:
 Enucleation ,resection –for smaller lesions
 Large posteriorly located lesions- resection similar to
ameloblastoma
MALIGNANT TUMOURS OF THE
MAXILLARY SINUS
Harrison’s classification of maxillary sinus
malignancies:
 T1- Limited to the antral mucosa
 T2- bony erosion
 T3- involvement of facial skin, orbit, ethmoid
labrynth, or extension into pterygopalatine fossa
 T4- extension into the nasopharynx, sphenoid
sinus, cribriform plate, or pterygopalatine fossa
TNM STAGING:
 Tx – primary tumor cannot be assessed
 T0 – no evidence of primary tumor
 Tis – carcinoma in situ
 T1 – tumor limited to antral mucosa with no erosion or
bone destruction
 T2 – tumor causing bone erosion except for posterior
antral wall
 T3 – tumor invading bone of posterior wall, skin of cheek,
subcutaneous tissues, floor or medial wall of orbit,infra
temporal fossa ,pterygoid plates ,ethmoid sinuses
 T4 – tumor invading orbital contents including orbital
apex ,cribriform plate,base of skull ,naso
pharynx,sphenoid,frontal sinuses
• Signs /symptoms :
 Group 1:oral signs/symptoms:
Tooth ache, loose teeth
 Group 2:nasal signs/symptoms:
Congestion, rhinorrhea, & epistaxis
 Group 3:facial signs/symptoms
Cheek mass, facial asymmetry
 Group4:ocular signs/symptoms:
Found in 23% of patients & an ocular problem is the
presenting complaint in 5% of the patients
 Group5:neurologic signs/symptoms:
Involvement of adjacent branches of cranial nerves
 Diagnosis
 Insidious in onset
 Can extend superomedially,
medially,superiorly, inferiorly & anteriorly
Ohngren’s line from the medial
canthus of the eye to the angle
of the mandible. The
infrastructure of the maxillary
sine lies anterior to this line
and tumors of this area have a
better prognosis.
STAGING
 Biopsy techniques :
Endoscopic biopsy by enlarging the ostium
Classical nasal antrostomy beneath inferior
turbinate
Caldwell-luc approach
 MANAGEMENT
 Surgery
 Hemimaxillectomy & modifications like medial
maxillectomy
 Partial maxillectomy
 Sub total maxillectomy
 Total maxillectomy
 Maxillectomy with orbital exenteration
 Craniofacial resection
 Neck dissection
Approaches:
 Trans nasal
 Transoral and transpalatal
 Mid face deglowing
 Weber fergussion approach
 Lefort 1 osteotomy approach
 Combined cranio facial approach
Lateral rhinotomy
Classical WF
WF with lynch
WF with
lat sub ciliary
WF with
supra ciliary
Subtotal Maxillectomy
Larger lesions of the gums, palate or the antrum which
extend to the superior aspects or beyond the
confines of the antrum
Proposed Bonycuts
Total Maxillectomy
Primary tumours filling the entire antrum
In some cases infra orbital rim is preserved
RECONSTRUCTION:
 Autogenous grafts
 Non-autogenous grafts
 Resorbable
Gelatin,polyglactin,polydioxonone films
 Non-resorbable
Sheets of silicone,teflon,porous polypropylene,metallic
mesh
RECONSTRUCTION:
 Prosthesis
 Local flaps:palatal flaps
 Radial fore arm flap
 Temporalis &tempero parietal galeal flap
 Iliac crest free microvascular flap
RADIATION THERAPY
CHEMOTHERAPY & COMBINATION THERAPY
CIS-PLATINUM(100mg/m2/d/1d)
5-FLUOROUROCIL(1000mg/m2/d1-5x3cycles)
RAD PLAT PROTOCOL
CHEMOTHERAPY—CIS-PLATINUM(150mg/m2/wk/4wk) with EXTERNAL
BEAM RADIATION THERAPY(68-72 GY)
Conclusion
• Due to close proximity of maxillary sinus to
orbit, alveolar ridge, maxillary teeth, diseases
involving these structures may produce
confusing symptoms. Hence a precise
information about the surgical anatomy is
essential to surgeons.
THANK YOU

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SEMINAR_ON_MAXILLARY_SINUS.ppt

  • 2. Contents 1. Introduction 2. Embryology of maxillary sinus 3. Anatomy of maxillary sinus 4. Microscopic anatomy 5. Drainage of sinus 6. Functions of sinus 7. Classification of diseases of maxillary sinus 8. Maxillary sinusitis 9. Oroantral fistula 10. Benign and malignant tumors of maxillary sinus 11. Approaches to maxillary sinus 12. Conclusion 13. References
  • 4. Maxillary sinus  Pneumatic space lodged in the body of maxilla that communicates with the external environment by way of middle meatus and nasal vestibule - by Orban’s  Also known as antrum of Highmore (1651)
  • 6. • Development of sinus begins as evagination of mucus membrane in lateral wall of middle meatus when nasal epithelium invades maxillary mesenchyme ( Kitamura, 1989) • Growth of sinus takes place by pneumatization  Primary (10th weeks)  Secondary (5th month)
  • 7. • Post natally grows @ 2 mm vertically and 3 mm AP • 3 growth spurts a) 0-2.5 years b) 7.5-10 years c) 12-14 years
  • 9.
  • 11.
  • 12.  Base-Lateral wall of nose  Apex – projects laterally into zygomatic process of maxilla  Roof – orbital floor  Floor – alveolar process of maxilla which supports premolars and molars  Posterior wall – infra-temporal and pterygo- palatine fossa  Anterior wall – facial surface of maxilla
  • 13. Medial wall IMP STRUCTURES:  Sinus ostrium  Hiatus semilunaris  Ethmoidal bulla  Uncinate process  Infundibulum
  • 14. Natural ostium • Located in posterior ½ of infundibulum or behind lower1/3 of uncinate process. • Tunnel shaped, length: 1- 22mm;3-6mm diameter • Unfavorable position for gravity dependent drainage • Post edge-continuous with lamina papyracea(imp for surgical dissection)
  • 15. Superior wall • Forms roof of sinus and floor of orbit • Imp structures • Infra orbital canal • Infra orbital foramen • ASA nerve • Applied aspect
  • 16. Posterolateral wall  Made of zygomatic and greater wing of sphenoid bone(maxillary tuberosity)  Imp structures  PSA nerve  Maxillary artery  Maxillary nerve  Pterygopalatine ganglion  Nerve of pterygoid canal
  • 17. Anterior wall • Extends from pyriform aperture anteriorly to ZM suture & IO rim superiorly to alveolar process inferiorly. • Imp structures  Infraorbital foramen  ASA, MSA nerves  Levator labii, obicularis oculi muscles
  • 18. Floor of sinus • Formed by junction of anterior sinus wall and lateral nasal wall • 1-1.2 cm below nasal floor
  • 19. Vascularization & innervation Arterial Supply a) Nasal MucosalVasculature SP, Ethmoid b) OsseousVasculature IO, PSA,ASA,GP, Facial Venous Drainage a) Medial wall - SP b) Other walls – Pterygomaxillary Plexus Lymphatic Drainage Collecting vessels in middle meatus Nerve Innervation ION, GP, PSA, MSA, ASA
  • 20. Microscopic anatomy • 3 layers  Epithelium  Basal lamina  Sub epithelium Pseudo stratified columnar ciliated epithelium • Cells  Columnar ciliated  Goblet  Basal  Non – ciliated
  • 21. Drainage of sinus Mucociliary flow from anterior sinuses converge at OMC, carried to posterior nasopharynx & inferiorly to eustachian tube orifice Mucus coursing along lateral wall, carried medially along roof to reach ostium Drainage into ethmoidal infundibulum Upward course along walls of entire cavity and then towards natural ostium in superomedial wall Flow of mucus superiorly against gravity By Donald et al & Antunes et al
  • 23. Functions of sinus 1. Decrease skull weight 2. Impart resonance to voice 3. Mucus production and storage 4. Humidify and warm inhaled air 5. Define facial contour 6. Immunodefensive action 7. Conserve heat from nasal fossae 8. Moisturize air 9. Filters debris 10. Dampen pressure differential during inspiration 11. Limit extent of facial injury from trauma 12. Serves as accessory olfactory organ
  • 24. Classification of diseases  Maxillary sinusitis :Inflammatory  odontogenic  Oro antral fistula :acute and chronic  Traumatic: hematoma in sinus  Iatrogenic: tooth or root displaced into sinus  Cysts of the maxillary sinus  Intrinsic origin-  Mucocele  Serous cyst  Choleosteatoma  Extrinsic origin  OKC  Radicular cyst
  • 25.  Tumors:  1.Benign tumors  Intrinsic origin-  Papilloma  Juvenile angio fibroma  Extrinsic origin  Ameloblastoma  Odontoma  CEOT  2.Malignant tumors: carcinoma of maxillary sinus  Tumor like lesions  Fibrous dysplasia  Ossyifying fibroma  Antral rhinoliths
  • 28. Maxillary sinusitis 1. Infectious causes a) Bacterial b)Viral c) Fungal d) Parasitic 2. Non infectious causes a)Allergic b) Non allergic c) Pharmocologic d) Irritants 3. Disruption of mucociliary drainage a) Surgery b) Infection c)Trauma Extrinsic causes 1. Genetic a) Structural b) Immunodeficiency c) Mucociliary abnormality (cystic fibrosis, dismotility) 2. Acquired a) Aspirin hypersensitivity b)Autonomic dysregulation c) Hormonal d) Structural (Tumors, cysts) e)Idiopathic/ autoimmune f) Immunodeficiency Intrinsic causes
  • 29. Acute maxillary sinusitis :haemophilus influenzae, streptococcus pneumoniae, or maraxella catarrhalis. chronic sinusitis : anaerobic and polymicrobial and more likely to involve staphylococcus aureus. odontogenic etiology related with first molar infection with mucostasis of other cause. ETIOLOGY OF MAXILLARY SINUSITIS:
  • 30. DIAGNOSIS: SYMPTOMS:: maxillary pain, pressure, pain similar to toothache, CLINICAL FINDINGS: fever, throat-clearing cough, purulent rhinorrhea, hyposmia, headache, malaise, maxillary anterior wall tenderness to percussion, purulence noted, in cases associated with cellulitis ,facial swelling and erythema seen , RADIOGRAPH: —water’s view, fluid opacification of maxillary sinus CT SCAN
  • 31. SIGNS AND SYMPTOMS OF ACUTE MAXILLARY SINUSITIS SIGNS:  Pain on pressure over the anterior maxillary sinus wall.  Purulent discharge over the inferior nasal turbinate.  Fever  Malaise SYMPTOMS  Cheek pain with referral to frontal region.  Increased pain on bending.  Maxillary posterior teeth free like “pegs”  Hyposmia
  • 32. MELENS CRITERIA FOR CHRONIC SINUSITIS :  Facial pain, nasal congestion or abnormal secretions remain or reappear during a period of at least 3 months.  Sinus radiography or sinus endoscopy reveals persistent localized or generalized mucosal swelling with or without secretions.  Chronic maxillary sinusitis of rhinogenous origin that does not heal after conservative treatment.  Chronic maxillary sinusitis of dental origin.
  • 33. Maxillary sinusitis  Diagnosis 1. History 2. Physical examination  Inspection  Palpation  Percussion  Diagnostic techniques a. Rhinoscopy b. Endoscopy c. Culture and sensitivity
  • 34. Maxillary sinusitis 3. Radiological examination a) Lateral view b) CT scan c) MRI 4. Tests for mucociliary functions a) Naso mucociliary clearance b) Ciliary beat frequency c) Rhino manometry 5. Test for olfaction
  • 35. Maxillary sinusitis Management Medical 1. Antibiotics 2. Steroids 3. Decongestants 4. Analgesics 5. Antihistamines 6. Nasal spray & saline irrigation 7. Hydration 8. Mucolytics Surgical 1. sinus aspiration and lavage 2. Maxillary needle sinusotomy 3. Caldwell luc 4. FESS
  • 36. Antibiotics Antibiotic Micro factors FIRST LINETHERAPY Amoxicillin 45 mg/kg/day or 90 mg/kg/day divided Amoxicillin/potassium calvulanate 22.5-45 mg/kg/day divided (dose based on amoxicillin component) Azithromycin 10 mg/kg/day on day 1, then 5 mg/kg/day on days 2- 5 Cefdinir 14 mg/kg/day Cefpodoxime 10 mg/kg/QID Cefprozil 15 mg/kg/QID Cefuroxime 15 mg/kg/QID Ciprofloxacin Clarithromycin 7.5 mg/kg/day Cindamycin 8-20 mg/kg/day dividedQID Doxycycline Garifloxacin Levofloxacin Sulfamethoxazole/trimethoprim 6-12 mg/kg/day divided (based on trimethoprim)
  • 37. 1.Steroids: • 1st line of therapy: topical intranasal (beta methasone, dexa methasone, triamcinolone) • Systemic steroids: • Prednisolone:0.5-1mg/kg x3-4 days 2.Decongestants: Systemic (phenyl propanolamine, pseud oephidrine): • Contraindications: hypertension, hyperthyroidism, asthma Topical: pheny lepinephrine HCl, oxy metazoline HCl • Adv. Effects- rhinitis medicamentosa 3.Analgesics: • Opioid: acetaminophen, codeine • NSAIDS: 4.Antihistamines: • Mequitazine, terfenad • Contraindicated in bacterial sinusitis • Adv effect: sedation
  • 38. Nasal lavage & sprays • Removes debris & dead tissue • Washes inflammatory secretions • Eliminates nutrient source • Methods: • Lavage pot • Syringe • Irrigating bulb
  • 39. Surgical management Indications • Bilateral chronic sinusitis with polyps • Fungal sinusitis • Presence of complications • Tumor of PNS • CSF rhinorrhea Contraindications • Presence of extensive polyps • Pt with complaint of headache and mid facial pain • Medically compromised • Hypo plastic sinuses
  • 40. Sinus aspiration & lavage  Direct removal of bacteria laden secretions  Indication: no response to medical therapy
  • 41. Maxillary needle sinusotomy • Complications: • Bleeding • Infection • Dental injury • Sensory nerve disturbance • Instrument breakage Infiltration of LA Preparation of site Transcutaneous puncture ant & post to canine eminence
  • 42. Caldwell luc sinusotomy  By George Caldwell (1893) & Henry Luc (1897)  Indications  Fungal sinusitis  Multiple antral lesions  Antrochoanal polyp  Excision of tumor  Closure of OAF  Removal of antral foreign body  surgical approach for transantral spheno ethmoidectomy, orbital decompression
  • 43. Caldwell luc sinusotomy Complications •Bleeding •Dental sensitivity •Infraorbital neuralgia •Osseous defect in anterolateral wall •Entrapment of inferior rectus muscle
  • 44. FESS  Coined by Kennedy  Principle: stop the cycle that begins with ostium blockage that leads to chronic sinusitis via stagnated secretions, tissue inflammation and bacterial infections.
  • 45. FESS
  • 46. FESS
  • 47. FESS Minor hemorrhage Hyposmia Adhesions Periorbital emphysema Intracranial hemorrhage Brain injury CSF leak Diplopia Blindness Anosmia Epistaxis NL duct injury Meningitis Complications
  • 48. Complications of untreated maxillary sinusitis:  Complications:  Facial cellulitis  Orbital extension  Intracranial extension
  • 49. DISPLACED ROOT OR TOOTH INTO THE SINUS  Most common complication following tooth extraction.  Roots are those of the 1st molar (80%) with slightly less than 20 % are 2nd molar and the remainder involving the 3rd molar and 2nd premolar and rarely the canines
  • 50. Procedure to retrieve broken root tip from antrum:  Place the pt in upright position Determine the location of tooth /root tip Determine antral perforation/IOPA has to be taken If it in the sinus Place small suction tip in to sinus through the socket gently/saline irrigation can be done Pack 0.5inch long iodoform gauge in to the sinus &pull it out in one stretch Cald well luc sinusotomy
  • 51. SINUS EXPOSURE FOLLOWING TUBEROSITY FRACTURE  Prevented by preliminary expansion of the socket  In multiple extractions 3 rd molar should be extracted 1 st  Discontinue the extraction  Fixation is done by an arch bar, acrylic splint or an orthdontic appliance
  • 53. OROANTRAL FISTULA  Etiology • Iatrogenic (50%) • Presence of periapical lesions • Injudicious use of instruments • During attempted extraction • Trauma(7.5%) • Chronic infections(11%) • Malignant diseases(18.5%) • Infected maxillary dentures(3.7%) • h/o sinus surgery(7.5%) Predisposing factors
  • 54. Acute Chronic 1. Escape of air and fluids through nose & mouth 1.Pain, tenderness over cheeks which is dull and boring type 2. Epistaxis 2. Purulent discharge 3. Excruciating pain 3. Post nasal drip 4. Altered voice due to enhanced column of air 4. Presence of polyps 5. h/o surgery in vicinity of sinus, escape of fluids in to the nose 5. Generalized constitutional symptoms Signs & symptoms of oroantral fistula
  • 55. Diagnosis H/o previous extraction Mouth mirror test Nose blow test Cotton wisp test Inspection Radiological  IOPA  OPG
  • 56. MANAGEMENT • 3mm-5mm heals spontaneously • Acute OAF: closure by simple reduction of buccal and palatal socket walls, followed by acrylic splint. 1) Antibiotics : Penicillin & derivatives 2) Nasal decongestants:  Ephedrine drops  Inhalations(steam , benzoin ,menthol) 3) Analgesics:  Aspirin 500mg  Paracetamol 500mg  Ibuprofen 400 mg 4) Antral lavage
  • 57. Surgical management: Closure of Oroantral Communications:A Review of the Literature, Susan H. Visscher et al, J Oral Maxillofac Surg68:1384-1391, 2010 •Temporalis flap •Forehead flap Overview of the treatment modalities of Oro-Antral Communications
  • 58. Surgical closure • Factors determining flap selection • Size of communication • Timeline of diagnosing • Presence of infection
  • 59. Buccal flap: The defects can be closed by a. Advancement flaps b. Sliding flaps
  • 60. Buccal advancement flap Adv:  Broad base  No denuded area Disad: Depth of buccal vestibule obliterated
  • 61. Buccal sliding flap  Moczair described it  Minimal change in buccal vestibule  Facilitates distal shift of flap  Disad:  Raw surface anteriorly  Gingival recession
  • 62. Modified BuccalAdvancement Flap Laskin and Robinson described it first A clinical study on oro antral fistula; J cranio maxillofacial surg.1998;26;267-71
  • 63. Palatal Flaps: These includes a. Straight advancement b. Rotational advancement c. Island palatal flap d. Hinged palatal flap
  • 65. RotationalAdvancement Flap: Ø Kruger suggested V- shaped excision of tissue on the lesser curvature to minimize folding the flap.
  • 66. Sub mucosal Connective Tissue Flap: Ito and Hara described elevation of full-thickness palatal flap followed by creation of a submucosal connective tissue flap to close the fistula and return of the remainder of the flap to lower the original donor site.
  • 67. Island Palatal Flap: Hendersen has described the use of a palatal pedicle island flap. Because of the mobility of this flap and its excellent blood supply it can be used to close larger defect. James suggested that sectioning the island should be done best so that the tissue can still be used as a rotational advancement flap or rotational to tits original site will cause injury to its vessels.
  • 68. Hinged Flap: The mucoperiosteum on the palatal aspect of the oroantral fistula can be used as a hinged flap to close small opening.
  • 69. Combined Local Flaps: They are Simple Transverse Bipedicled Buccopalatal flap These are practiced where there is sufficient large edentulous surface. Combination of inversion and rotational advancement flaps. Double hinged flaps. Double island flaps. Superimposed reverse palatal buccal flaps.
  • 70. Distant Flaps 1. Flap from extremities 2. Flap from forehead 3. Tongue flap 4. Temporalis flap 5. Buccal fat pad flap
  • 71. BUCCAL FAT PAD Use of pedicled buccal fat pad in closure of oro antral communication; analysis of 75 cases Dolanmaz et.al., Quintessence international 2004: 35(3) ; 241-426
  • 72. TONGUE FLAP Introduced by lexer,1909 Technique Advantages Disadvantages Use of the tongue flap for intra oral reconstruction; report of 16 case Kim, Yeo and Kim J Oral Maxillofac Surg 1998; 56: 716-719
  • 73. TEMPORALIS FLAP:  Advantages: Proximity to the oral cavity. Safety of it vascular pedicle. Its pliability Minimal functional and esthetic sequelae Less dysfunction during healing.  Procedure:
  • 75. Grafts GRAFTS AUTOGENOUS Iliac crest Chin Retromolar area Zygoma Brusati has used bone from lateral wall ALLOGENOUS Collagen sheet Fibrin glue Gold foil Tantalum PMMA Hydroxyapatite XENOGRAFTS Porcine dermis Bio guide & Bio oss
  • 76. Other techniques • Third molar transplantation(kitagawa et al) • Interseptal alveolotomy(hori et al) • GTR(Waldrop & Semba) • Prolamine gel(Gotzfried & Kaduk) • Laser light(Janas) • Splints for immunocompromised pts(llogan and coates) • Allotransplants of fasvia lata and dura matter(guven;1995) • Buccinator myo mucosal island flap(J.OralMaxillofacial Surg;2002;60;816-821)
  • 77. THE EFFECTS OF TRAUMAON THE MAXILLARY SINUS The effects of traumatic sinus disruption vary from: -Chronic sinusitis -Polyps -Mucocele formation -Acute sinusitis with extension to more vital organs
  • 78.  Any midfacial trauma --clouding of the sinus  ZMC fracture involves inferior orbital fissure --orbital floor is often comminuted creating multiple fracture lines in roof of the maxillary sinus  Fractures of the internal orbit --teardrop radioopacity  Lefort fractures --involve maxillary sinus
  • 79. Response of maxillary sinus to trauma a)Mucosal regeneration b)Bony regeneration
  • 80. Management:  Generally does not require direct treatment  The sinus regenerates after the hemorrhagic fluids have been removed by mucociliary action  Gross debris must be removed before closing the soft tissues overlying it
  • 81. Reconstruction of sinus walls:  Common area is roof of sinus (floor of the orbit)  Indications: enoptholmos, exopthalmos, diplopia, isolated sinus wall defects Autogenous  Eg: calvarial, iliac crest Nonautogenous  Eg: lyophilized dura, siloxane, teflon and other bioresorbable materials,grafts
  • 82. INFECTIOUS DISEASES OF THE MAXILLARY SINUS  Aspergillosis : Caused by the fungus aspergillus Immune compromise is common Severe neutropenia H/O recent treatment with cytotoxic drugs & corticosteroids
  • 83.  Aspergillosis : Thick ,dark greasy material is found in the sinus  Three types are seen: Non invasive Invasive Fulminant Treatment includes aggressive debridement & systemic antifungal therapy
  • 84.  Mucormycosis : Caused by fungi of the class phycomycetes Infection is usually fatal Impaired chemotaxis & phagocytic activity Virulent strain can cause thrombosis ,ischaemia & necrosis
  • 85.  Clinical signs of advanced disease are:  Proptosis  Opthalmoplegia  Anesthesia of trigeminal nerve distribution  Cavernous sinus thrombosis  Facial palsy Management includes  Correction of the underlying metabolic/hematologic abnormality  Aggressive debridement & Systemic antifungal therapy
  • 86. Maxillary antrolithiasis:  Asymptomatic or pain, nasal obstruction, epistaxis, sinusitis.  Investigation:  Radiographs – opaque mass  Treatment – surgical removal
  • 87. BENIGN MUCOSAL CYST • Most common cyst • Due to obstruction of the glandular ducts. Clinical features: 1. Discomfort in the cheek or maxilla. 2. Buccal expansion of the antrum. 3. Nasal obstruction. 4. Post nasal discharge. 5. External deformity of the face.
  • 88. Radiographic features: appear as rounded lightly opaque shadow in the floor of the sinus. Aspiration: through inferior turbinate will reveal straw or amber-coloured fluid “cholesterol crystals”. Treatment: Asymptomatic: monitor 1. Cannulation through inferior turbinate puncture. 2. Marsupialization 3. Enculeation through cald well. Luc operation with nasal antrostomy.
  • 89. Odontogenic keratocyst:  Maxillary OKC’S occur primarily in the 3 rd molar region with canine being the 2 nd most common site  Peak incidence is in 2 nd & 3 rd decades
  • 90. TUMOURS OF THE MAXILLARY SINUS  Ameloblastoma  Antrum & nasal floor are common sites Most cases arise extrinsic to the sinus Present as an enlarging mass  Management : en bloc excision with good surgical margins
  • 91. CALCIFYING EPITHELIAL ODONTOGENIC TUMOUR  Arises from the epithelial remnants of the enamel organ  Comprises 1% of all odontogenic tumours  Slow growing painless swelling  Age :40 years approximately
  • 92. CEOT  MANAGEMENT:  Enucleation ,resection –for smaller lesions  Large posteriorly located lesions- resection similar to ameloblastoma
  • 93. MALIGNANT TUMOURS OF THE MAXILLARY SINUS Harrison’s classification of maxillary sinus malignancies:  T1- Limited to the antral mucosa  T2- bony erosion  T3- involvement of facial skin, orbit, ethmoid labrynth, or extension into pterygopalatine fossa  T4- extension into the nasopharynx, sphenoid sinus, cribriform plate, or pterygopalatine fossa
  • 94. TNM STAGING:  Tx – primary tumor cannot be assessed  T0 – no evidence of primary tumor  Tis – carcinoma in situ  T1 – tumor limited to antral mucosa with no erosion or bone destruction  T2 – tumor causing bone erosion except for posterior antral wall  T3 – tumor invading bone of posterior wall, skin of cheek, subcutaneous tissues, floor or medial wall of orbit,infra temporal fossa ,pterygoid plates ,ethmoid sinuses  T4 – tumor invading orbital contents including orbital apex ,cribriform plate,base of skull ,naso pharynx,sphenoid,frontal sinuses
  • 95. • Signs /symptoms :  Group 1:oral signs/symptoms: Tooth ache, loose teeth  Group 2:nasal signs/symptoms: Congestion, rhinorrhea, & epistaxis  Group 3:facial signs/symptoms Cheek mass, facial asymmetry  Group4:ocular signs/symptoms: Found in 23% of patients & an ocular problem is the presenting complaint in 5% of the patients  Group5:neurologic signs/symptoms: Involvement of adjacent branches of cranial nerves
  • 96.  Diagnosis  Insidious in onset  Can extend superomedially, medially,superiorly, inferiorly & anteriorly
  • 97. Ohngren’s line from the medial canthus of the eye to the angle of the mandible. The infrastructure of the maxillary sine lies anterior to this line and tumors of this area have a better prognosis. STAGING
  • 98.  Biopsy techniques : Endoscopic biopsy by enlarging the ostium Classical nasal antrostomy beneath inferior turbinate Caldwell-luc approach
  • 99.  MANAGEMENT  Surgery  Hemimaxillectomy & modifications like medial maxillectomy  Partial maxillectomy  Sub total maxillectomy  Total maxillectomy  Maxillectomy with orbital exenteration  Craniofacial resection  Neck dissection
  • 100. Approaches:  Trans nasal  Transoral and transpalatal  Mid face deglowing  Weber fergussion approach  Lefort 1 osteotomy approach  Combined cranio facial approach
  • 101. Lateral rhinotomy Classical WF WF with lynch WF with lat sub ciliary WF with supra ciliary
  • 102. Subtotal Maxillectomy Larger lesions of the gums, palate or the antrum which extend to the superior aspects or beyond the confines of the antrum Proposed Bonycuts
  • 103. Total Maxillectomy Primary tumours filling the entire antrum In some cases infra orbital rim is preserved
  • 104. RECONSTRUCTION:  Autogenous grafts  Non-autogenous grafts  Resorbable Gelatin,polyglactin,polydioxonone films  Non-resorbable Sheets of silicone,teflon,porous polypropylene,metallic mesh
  • 105. RECONSTRUCTION:  Prosthesis  Local flaps:palatal flaps  Radial fore arm flap  Temporalis &tempero parietal galeal flap  Iliac crest free microvascular flap
  • 106. RADIATION THERAPY CHEMOTHERAPY & COMBINATION THERAPY CIS-PLATINUM(100mg/m2/d/1d) 5-FLUOROUROCIL(1000mg/m2/d1-5x3cycles) RAD PLAT PROTOCOL CHEMOTHERAPY—CIS-PLATINUM(150mg/m2/wk/4wk) with EXTERNAL BEAM RADIATION THERAPY(68-72 GY)
  • 107. Conclusion • Due to close proximity of maxillary sinus to orbit, alveolar ridge, maxillary teeth, diseases involving these structures may produce confusing symptoms. Hence a precise information about the surgical anatomy is essential to surgeons.

Editor's Notes

  1. Inner surface is rough by bony septa Retrieval of root fragment Interferes with sinus drainage
  2. Intranasal endoscopic technique that allows establishment of adequate sinus drainage without negative impact on sinus mucosa physiology and function.