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•  Improved Outcomes: For topical preparations, there was
significant evidence to support the use of controlled release iodine
dressings.1
•  In combination with compression therapy, there was significant
evidence of greater complete healing1 by weeks 4 through 6.
•  Even in the absence of compression therapy, there remained
significant evidence of faster healing rates1 for controlled release
iodine dressings (p<0.05).
•  Alternatively, significant evidence to support improved
outcomes was not found for silver dressings in no less than
three separate and independent Cochrane Reviews.2,3,4
•  Cost to Treat: Controlled release iodine demonstrated significantly
less costs1 in dollars per cm2 of wound area reduction.
Reimbursement / Access: IodoFoam® is the only controlled
release iodine dressing with full & defined Medicare reimbursement.
Highest Level of Evidence Based Outcomes
Findings of the Cochrane Collaboration reviews of
topical antimicrobials for wounds:
Antibiotics and antiseptics for venous leg ulcers (Review)
O’Meara S, Al-Kurdi D, Ologun Y, Ovington LG
This is a reprint of a Cochrane review, prepared and maintained by The Cochrane Collaboration and published in The Cochrane Library
2010, Issue 10
http://www.thecochranelibrary.com
Antibiotics and Antiseptics for
Venous Leg Ulcers (Review)
O’Meara S, Al-Kurdi D, Ologun Y, Ovington LG. The Cochrane Library
2010, Issue 10.
® Registered Trademark of the Cochrane Collaboration.
1.  Antibiotics and antiseptics for venous leg ulcers., Cochrane Library 2010, Issue 10."
2.  Silver based wound dressings and topical agents for treating diabetic foot ulcers.,
Cochrane Library 2006, Issue 1."
3.  Topical silver for preventing wound infection. Cochrane Library 2010, Issue 3."
4.  Topical silver for treating infected wounds., Cochrane Library 2007, Issue 1."

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  • 1. •  Improved Outcomes: For topical preparations, there was significant evidence to support the use of controlled release iodine dressings.1 •  In combination with compression therapy, there was significant evidence of greater complete healing1 by weeks 4 through 6. •  Even in the absence of compression therapy, there remained significant evidence of faster healing rates1 for controlled release iodine dressings (p<0.05). •  Alternatively, significant evidence to support improved outcomes was not found for silver dressings in no less than three separate and independent Cochrane Reviews.2,3,4 •  Cost to Treat: Controlled release iodine demonstrated significantly less costs1 in dollars per cm2 of wound area reduction. Reimbursement / Access: IodoFoam® is the only controlled release iodine dressing with full & defined Medicare reimbursement. Highest Level of Evidence Based Outcomes Findings of the Cochrane Collaboration reviews of topical antimicrobials for wounds: Antibiotics and antiseptics for venous leg ulcers (Review) O’Meara S, Al-Kurdi D, Ologun Y, Ovington LG This is a reprint of a Cochrane review, prepared and maintained by The Cochrane Collaboration and published in The Cochrane Library 2010, Issue 10 http://www.thecochranelibrary.com Antibiotics and Antiseptics for Venous Leg Ulcers (Review) O’Meara S, Al-Kurdi D, Ologun Y, Ovington LG. The Cochrane Library 2010, Issue 10. ® Registered Trademark of the Cochrane Collaboration. 1.  Antibiotics and antiseptics for venous leg ulcers., Cochrane Library 2010, Issue 10." 2.  Silver based wound dressings and topical agents for treating diabetic foot ulcers., Cochrane Library 2006, Issue 1." 3.  Topical silver for preventing wound infection. Cochrane Library 2010, Issue 3." 4.  Topical silver for treating infected wounds., Cochrane Library 2007, Issue 1."