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STOP WATCH TESTING
An analysis into the use of a new testing technique to
identify and treat concussions
By Peter Eggleston Connor
Data provided by
Southern Oregon Orthopedics
A Graduate Thesis from
Southern Oregon University
TERMINOLOGY
Reaction Time
Healthy / Injured / Recovering
Days Since Injury (or: Recovery Time)
Symptom Score
HISTORY
• Prior to 2001: Concussion detection had little empirical evidence
supporting it.
• 2001-2012: American Academy of Neurology (AAN) creates guidelines
for more globally accessing concussion risks in athletes.
• 2013: An update came out pointing towards evidence that having a
concussion made future concussions more likely.
OBJECTIVES
• Identify changes between healthy and injured reaction times
• Determine a concussion recovery rate based on reaction time
• Identify significant symptom scores over course of recovery
DATA COLLECTION – HEALTHY AND INJURY FORM
DATA COLLECTION – RECOVERING FORM
DATA ORGANIZATION
DESCRIPTIVE ANALYSIS
DESCRIPTIVE ANALYSIS – RECOVERY TIME
n = 39
Mean:
8.2 days
Standard Deviation:
5.3 days
90th Percentile:
~11 days
DESCRIPTIVE ANALYSIS – HEALTHY REACTION TIME
Mean:
0.18 sec
Standard Deviation:
0.03 sec
DESCRIPTIVE ANALYSIS –
HEALTHY REACTION TIME IN CONCUSSED PLAYERS
Mean:
0.18 sec
Standard Deviation:
0.02 sec
Hypothesis Test All vs
Concussed Healthy
Reaction Times
p-value:
0.16
Conclusions:
Accept Null
DESCRIPTIVE ANALYSIS – INJURED REACTION TIME
Mean:
0.27sec
Standard Deviation:
0.10sec
Hypothesis Test Healthy vs
Injured Reaction Time in
Concussed Athletes
p-value:
~1
Conclusion:
Reject Null
DESCRIPTIVE ANALYSIS –
REACTION TIME DIFFERENCES
Mean:
.088 sec
Standard Deviation:
.098 sec
DESCRIPTIVE ANALYSIS – REACTION TIME RATIOS
Mean:
1.49
Standard Deviation:
0.52
COMPARE
DAYS
TO
REACTION
TIME
EXPONENTIAL
MODELING:
DIFFERENCE 𝑦 = (𝑐 − ℎ) 𝑒 𝛽𝑡
+ ℎ
y: The reaction time at t days since injury
c: The reaction time at the time of injury
h: The healthy reaction time
β: The rate of decay in the reaction time during recovery
t: The number of days since the concussion injury
EXPONENTIAL
MODELING
𝑦 = (𝑐 − ℎ) 𝑒 𝛽𝑡 + ℎ
Purple:
β = .01
Red:
β = .2
Blue:
β = 1
EXPONENTIAL
MODELING:
DIFFERENCES
𝑦𝑖 = ( 𝑐 𝑖 − ℎ𝑖 )𝑒−𝛽𝑡
+ ℎ𝑖
EXPONENTIAL
MODELING:
DIFFERENCES
Where:
i: Index for patient histories (1 to 39)
ŷ: The predicted reaction time at t days since injury
Objective: Find the β that minimizes
𝑖
𝑛
𝑗
𝑚 𝑖
𝑦𝑖 − ŷ𝑖
2
PREDICTIVE
MODEL
USING
DIFFERENCES
𝑦 = 𝑐 − ℎ 𝑒−0.5441𝑡 + ℎ
With β selected as 0.5441
𝑟2
is optimized at 0.62
PREDICTIVE MODEL USING DIFFERENCES
Can be transformed into:
𝑡 𝑦,𝑖 =
𝑙𝑜𝑔(
𝑘
𝑐𝑖 − ℎ𝑖
−0.5441
Where 𝑘 = 𝑦 − ℎ𝑖
PREDICTIVE MODEL USING DIFFERENCE BETWEEN HEALTHY
AND INJURY
𝑡 𝑦,𝑖 =
log(
𝑘
𝑐𝑖 − ℎ𝑖
−0.5441
Optimal k:
0.0014
Mean:
6.97 Days
Standard Deviation:
1.52 Days
EXPONENTIAL MODELING: RATIO
𝑦𝑖
ℎ𝑖
= (
𝑐𝑖
ℎ𝑖
− 1 )𝑒−𝛽𝑡 + 1
EXPONENTIAL MODELING: RATIO
Objective: Find the β that minimizes
𝑖
𝑛
𝑗
𝑚 𝑖 𝑦𝑖
ℎ𝑖
− (
𝑦𝑖
ℎ𝑖
)
2
Where:
(
𝑦 𝑖
ℎ 𝑖
) : Is the predicted ratio
PREDICTIVE MODEL USING RATIOS
With β selected as 0.5696
𝑟2 is optimized at 0.43
𝑦𝑖
ℎ𝑖
= (
𝑐𝑖
ℎ𝑖
− 1 )𝑒−0.5696𝑡 + 1
PREDICTIVE MODEL USING RATIOS
To predict days until RTP:
𝑡 𝑦,𝑖 =
𝑙𝑜𝑔(
𝑝∗ℎ 𝑖
𝑐 𝑖−ℎ 𝑖
)
−0.5441
Where
𝑝 =
𝑦𝑖
ℎ𝑖
− 1
PREDICTIVE MODEL USING RATIOS OF
HEALTHY TO INJURY
Optimal p:
0.008
Mean:
6.97 Days
Standard Deviation:
1.50 Days
𝑡 𝑦,𝑖 =
𝑙𝑜𝑔(
𝑝∗ℎ 𝑖
𝑐 𝑖−ℎ 𝑖
)
−0.5441
SYMPTOMS  Blurry Vision
 Concentration
 Dizziness
 Fatigue
 Headache
 Heightened Feelings
 Light Sensitivity
 Loss of Balance
 Memory Loss
 Nausea
 Noise Sensitivity
 Sleeping Habits
SYMPTOMS COMPARED TO DAYS SINCE INJURY
HEADACHE EXAMPLE
SYMPTOM LINEAR MODELING:
SINGLE DESCRIPTIVE VARIABLE
Where:
y: Represents the response variable, days since injury
x: Represents the predictor variable, a symptom
𝑏0: Is the value of y when x is zero
𝑏1: The amount y changes when x increases by 1
𝑦 = 𝑏0 + 𝑏1 𝑥
SYMPTOM LINEAR MODELING:
MULTIPLE DESCRIPTIVE VARIABLES
Where:
n: Is the number of predictor variables used in the model
𝑥𝑙: Is a predictor variable value, where 𝑙 = 1, 2, … , 𝑛 are
symptoms
𝑏𝑙: The amount y changes when 𝑥𝑙 increases by 1
𝑦 = 𝑏0 + 𝑏1 𝑥1 + 𝑏2 𝑥2+. . . +𝑏 𝑛 𝑥 𝑛
SYMPTOMS
COMPARED
TO DAYS
SINCE INJURY
ANALYSIS OF
VARIANCE
(ANOVA)
• Identify Predictor Variables Independently
in Multivariable Experiments
• Assess Explained and Residual Variation of
Response Variable
• Determine Significance of Predictor
Variables on Response Variable
SYMPTOMS
COMPARED
TO DAYS
SINCE INJURY
ANOVA
SYMPTOMS COMPARED TO REACTION TIME
HEADACHE EXAMPLE
SYMPTOMS
COMPARED
TO
REACTION TIME
SYMPTOMS
COMPARED
TO
REACTION TIME
ANOVA
CONCLUSIONS:
DETERMINING A CONCUSSION OFF OF STOP WATCH
TESTING
The reaction times taken after injury were significantly different from
those of healthy times taken at the beginning of the season.
CONCLUSIONS:
RETURN TO PLAY
𝑡 𝑦,𝑖 =
𝑙𝑜𝑔(
0.008099
𝑐𝑖 − ℎ𝑖
−0.5441
Best Calculator:
Roughly 97.5% of cases recover in 10 Days.
CONCLUSIONS:
CONCUSSION SYMPTOMS
Headache, dizziness, fatigue, heightened feelings, and feeling nauseas
showed significance when looking at reaction time.
Headache showed significance when looking at days since injury.
FURTHER RESEARCH
Unconscious Incidents
Multiple Concussions
Correlation Coefficients in Linear Analysis
Larger Data Set

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Concussion projectdefenseversion2

Editor's Notes

  1. *: 1 of the concussions had no follow up data, so nothing was able to be gathered from it, leaving 39 concussions going forward.