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Assistant Lecturer
OB/GYN Department
Benha Faculty of Medicine
2019
 Introduction
 Epidemiology
 OBSTETRIC CRITICAL CARE
 BASIC PRINCIPLES FOR OBSTETRIC
EMERGENCIES
 Transfer to critical care setting
 Role of the Obstetrician–Gynecologist
 Resuscitative hysterotomy
 SUPPORTIVE CARE
 Recommendations and Conclusions
Items to be discussed
ICU receives obstetric patients with medical &
surgical emergencies as well as specific obstetric
complications
 Proportion of obstetric patients in most ICUs is low
Relative inexperience in management & team-work
between ICU team & obstetrician.
Introduction
Approximately (0.7–13.5) obstetric patients per
1,000 deliveries are admitted to ICU
Most common indications are postpartum
hemorrhage and hypertensive disorders
Most of these (63–92%) are postpartum
admissions
not require major lifesaving interventions but rather
more intensive monitoring than can be provided
on antepartum or postpartum units
Epidemiology
median length of stay was 2.0 days for women
admitted antepartum and 1.1 day for those
admitted postpartum
The maternal death rate after ICU admission
differs significantly between high- and low-income
countries (median 3.3% versus 14.0%, respectively,
P=.002)
Epidemiology
OBSTETRIC CRITICAL CARE
 Hypertensive disorders
 Obstetric hemorrhage
 Sepsis
 Thromboembolic and PE
 Trauma
 Respiratory conditions
 Cardiovascular disorders
 DKA
 Gastrointestinal disorders
 overdose or poisoning
 neurologic disorders
Leading causes of ICU admission
Top Causes of
Maternal mortality
Clinically unstable ( hypotensive or hypoxemic)
At high risk of deterioration
 Need specialized ICU care such as mechanical ventilation
Laboratory work
• arterial blood gas
• serum lactate
 The Quick Sequential Organ Failure Assessment can also be
used to stratify risk in patients who have infection
 Patients require
• level 2 care (monitoring and simple interventions)
• level 3 care (major organ support)
Factors contribute to the decision to
move a pregnant patient to ICU
Maternal Early Warning Criteria From the
National Partnership for Maternal Safety
Physiological changes in pregnancy modify:
• Presentation of the problem
• Normal physiological variables
• Response to treatment
 Both mother & fetus are affected by the pathology
& subsequent treatment.
Mother’s welfare always takes precedence over
fetal concerns
 Fetal survival dependent on optimal management
 If a pregnancy is complicated by a critical illness or
condition, the woman should be cared for at a
hospital with obstetric services, an adult ICU,
advanced neonatal care services, and appropriate
hospital services such as a blood bank.
It is important not to discourage ICU admission;
rather, encouraged to use critical care services when
appropriate
Obstetric hemorrhage
Hypertensive Emergency
(1st Line Therapy)
Septic shock
Pre-transport evaluation of the woman and her
fetus must be performed, and maternal status must be
stabilized before transport
 when transport is unsafe or impossible, or when imminent
delivery is anticipated, arrangements can be made for
postpartum rather than antepartum maternal transport
 If there is a high probability that intubation and mechanical
ventilation will be needed during transport, it should be
accomplished before departure
Transfer Between Hospitals
During transport :
• continuous cardiac rhythm and pulse oximetry monitoring
• regular assessment of vital signs
• Venous access must be established before transport
• Left uterine displacement should be routine
 obstetrician–gynecologists at the receiving hospital give an
opinion about medical interventions before arrival, or
prepare for interventions needed
Transfer Between Hospitals
 communication between the obstetrician–gynecologist and
critical care services is crucial. In some cases (eg, planned
cesarean hysterectomy
 possible to request an ICU bed in advance (planned)
 involve critical care staff early in the transfer process
 During transport, the team must be able to assess BP, heart
rate, and oxygenation status.
 For a critically ill patient , the team also should have a
cardiac monitor with defibrillator, airway management
equipment, oxygen, and basic resuscitation medications.
 At least two health care professionals should accompany the
patient during transport
Transfer Within the Hospital
 obstetrician–gynecologist’s role will depend on:
• patient status (antepartum or postpartum)
• ICU model and type
 According to ICU model , his role is
• open model >>>>>> 1ry physician
• closed model >>>>>> only to be consulted
• semi-open model >>>>>> MDT
 patient care decisions made collaboratively multidisciplinary
care team.
 Decisions also should involve the patient, her family, or both.
Role of the Obstetrician–Gynecologist
 weighing the risks and benefits of interventions such as
medication administration and diagnostic Imaging
 fetal monitoring
 delivery planning when indicated.
 Daily rounds, frequent communication with the ICU team
 rapid response to calls for consultation are all important
 evaluation of vaginal or surgical site bleeding
 obstetric sources of infection,
 therapies (such as magnesium for eclampsia prophylaxis),
 surgical issues, such as re-exploration of the abdomen or
reclosure of abdominal and perineal or vaginal incisions.
Role of the Obstetrician–Gynecologist
Regardless of the type of ICU
 The underpinning principles are that the woman’s interests
are paramount, and optimal fetal status is generally
predicated on optimizing the maternal condition as much as
possible.
 Medical interventions and diagnostic imaging may be
modified to an extent but when indicated for maternal
health should not be withheld purely for fetal concerns.
 It is important not to discourage ICU admission; rather,
encouraged to use critical care services when appropriate
Role of the Obstetrician–Gynecologist
Regardless of the type of ICU
Maternal stabilization is the first priority
 Once woman is stable, determine GA to plan of care,
immediate decision-making.
 Drugs that cross the placenta may have fetal effects
 Known adverse effects on the woman and the fetus must
be carefully monitored, and risk–benefit ratios assessed
Neither necessary medications nor diagnostic imaging
should be withheld from a pregnant woman because of
fetal concerns.
Special considerations in care of a pregnant
woman in a critical care setting
 Administration of steroids for fetal benefit
 Indicated delivery should not be delayed for
administration of steroids in the late preterm period
 Fetal monitoring
 In postpartum period, obstetricians should evaluate
vaginal or surgical site bleeding, therapies, surgical issues
 Provision of lactation support and a breast pump may
also be considered when feasible.
special considerations in care of a pregnant
woman in a critical care setting
Resuscitative hysterotomy
Resuscitative hysterotomy
Resuscitative hysterotomy
Mechanical ventilation
Sedation
 Vasopressors
 hemodynamic monitoring
SUPPORTIVE CARE
 Defined as interventions that sustain life and prevent
complications, but do not treat the cause of the critical
illness
 Normal physiology, pregnancy maintain respiratory
alkalosis (PaCO2 32 mmHg and arterial pH 7.4 to
7.47) due to respiratory stimulation by progesterone
 Mechanical ventilation is similar for pregnant and non-
pregnant women
 The major pregnancy-specific considerations are related
PaCO2. Target PaCO2 should be 30 to 32 mmHg
 PaCO2 values <30 mmHg or >40 mmHg to be avoided
 A reasonable goal is a maternal PaO2 above 65 mmHg
Mechanical ventilation
 Intubation and mechanical ventilation are undertaken
when hypoxemia is profound and cannot be corrected by
noninvasive means, or when ventilation is failing
 Airway management in pregnancy can be challenging
 Increased airway edema and increased breast size make
positioning and direct laryngeal visualization more
difficult.
 The risk of failed intubation in obstetrics is eight times
higher than in the general population
 Once the decision to intubate is made, the patient should
be preoxygenated and suction should be available; the
most qualified personavailable should intubate.
 A plan for failed intubation must be made ahead of time,
Mechanical Ventilation
 Interventions other than vasopressors should be used
initially to manage hypotension, including the IV fluids
and left lateral decubitus position.
 If Hypotension persists initiate vasopressor, since
sustained hypotension decreases uterine blood flow.
 For pregnant women, suggest norepinephrine as the
initial agent, rather than ephedrine, epinephrine or
dopamine (Grade 2C).
 If refractory shock , suggest the use of phenylephrine
rather than ephedrine (Grade 2C)
Vasopressors
 Most drugs used for analgesia, sedation, and paralysis
cross the placenta >>>>>> Possible adverse effects
 Consultation with an obstetrician and a pharmacist
 A neonatologist should be present at delivery because
may respiratory depression in the newborn
 Analgesia: Any opioid is acceptable. However, NSAIDs
should be avoided during late pregnancy
 Sedation:
* Midazolam is superior to lorazepam
* Propofol classified as a pregnancy category B agent.
 Neuromuscular blocker: Cisatracurium may be
preferable as a first line agent
Sedation
All patients should undergo conventional ICU
monitoring.
 Invasive hemodynamic monitoring especially when
hypoxemic respiratory failure (pulmonary edema)
accompanied by hypotension and/or renal failure.
 Using a central venous catheter to measure the
central venous pressure, rather than a pulmonary
artery catheter
Arterial catheter if BP is labile or frequent ABG needed
Hemodynamic monitoring
Recommendations and Conclusions
ACOG 2019 level A
Recommendations and Conclusions
ACOG 2019 level B
Recommendations and Conclusions
ACOG 2019 level B
Recommendations and Conclusions
ACOG 2019 level C
Recommendations and Conclusions
ACOG 2019 level C
Recommendations and Conclusions
ACOG 2019 level C
Recommendations and Conclusions
ACOG 2019 level C
09- Jul-18 Dr Shashwat Jani.
+919909944160. 63

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Critical Care of Pregnant Patients

  • 2.  Introduction  Epidemiology  OBSTETRIC CRITICAL CARE  BASIC PRINCIPLES FOR OBSTETRIC EMERGENCIES  Transfer to critical care setting  Role of the Obstetrician–Gynecologist  Resuscitative hysterotomy  SUPPORTIVE CARE  Recommendations and Conclusions Items to be discussed
  • 3. ICU receives obstetric patients with medical & surgical emergencies as well as specific obstetric complications  Proportion of obstetric patients in most ICUs is low Relative inexperience in management & team-work between ICU team & obstetrician. Introduction
  • 4. Approximately (0.7–13.5) obstetric patients per 1,000 deliveries are admitted to ICU Most common indications are postpartum hemorrhage and hypertensive disorders Most of these (63–92%) are postpartum admissions not require major lifesaving interventions but rather more intensive monitoring than can be provided on antepartum or postpartum units Epidemiology
  • 5. median length of stay was 2.0 days for women admitted antepartum and 1.1 day for those admitted postpartum The maternal death rate after ICU admission differs significantly between high- and low-income countries (median 3.3% versus 14.0%, respectively, P=.002) Epidemiology
  • 7.  Hypertensive disorders  Obstetric hemorrhage  Sepsis  Thromboembolic and PE  Trauma  Respiratory conditions  Cardiovascular disorders  DKA  Gastrointestinal disorders  overdose or poisoning  neurologic disorders Leading causes of ICU admission
  • 9. Clinically unstable ( hypotensive or hypoxemic) At high risk of deterioration  Need specialized ICU care such as mechanical ventilation Laboratory work • arterial blood gas • serum lactate  The Quick Sequential Organ Failure Assessment can also be used to stratify risk in patients who have infection  Patients require • level 2 care (monitoring and simple interventions) • level 3 care (major organ support) Factors contribute to the decision to move a pregnant patient to ICU
  • 10. Maternal Early Warning Criteria From the National Partnership for Maternal Safety
  • 11. Physiological changes in pregnancy modify: • Presentation of the problem • Normal physiological variables • Response to treatment  Both mother & fetus are affected by the pathology & subsequent treatment. Mother’s welfare always takes precedence over fetal concerns  Fetal survival dependent on optimal management
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  • 17.  If a pregnancy is complicated by a critical illness or condition, the woman should be cared for at a hospital with obstetric services, an adult ICU, advanced neonatal care services, and appropriate hospital services such as a blood bank. It is important not to discourage ICU admission; rather, encouraged to use critical care services when appropriate
  • 21. Pre-transport evaluation of the woman and her fetus must be performed, and maternal status must be stabilized before transport  when transport is unsafe or impossible, or when imminent delivery is anticipated, arrangements can be made for postpartum rather than antepartum maternal transport  If there is a high probability that intubation and mechanical ventilation will be needed during transport, it should be accomplished before departure Transfer Between Hospitals
  • 22. During transport : • continuous cardiac rhythm and pulse oximetry monitoring • regular assessment of vital signs • Venous access must be established before transport • Left uterine displacement should be routine  obstetrician–gynecologists at the receiving hospital give an opinion about medical interventions before arrival, or prepare for interventions needed Transfer Between Hospitals
  • 23.  communication between the obstetrician–gynecologist and critical care services is crucial. In some cases (eg, planned cesarean hysterectomy  possible to request an ICU bed in advance (planned)  involve critical care staff early in the transfer process  During transport, the team must be able to assess BP, heart rate, and oxygenation status.  For a critically ill patient , the team also should have a cardiac monitor with defibrillator, airway management equipment, oxygen, and basic resuscitation medications.  At least two health care professionals should accompany the patient during transport Transfer Within the Hospital
  • 24.  obstetrician–gynecologist’s role will depend on: • patient status (antepartum or postpartum) • ICU model and type  According to ICU model , his role is • open model >>>>>> 1ry physician • closed model >>>>>> only to be consulted • semi-open model >>>>>> MDT  patient care decisions made collaboratively multidisciplinary care team.  Decisions also should involve the patient, her family, or both. Role of the Obstetrician–Gynecologist
  • 25.  weighing the risks and benefits of interventions such as medication administration and diagnostic Imaging  fetal monitoring  delivery planning when indicated.  Daily rounds, frequent communication with the ICU team  rapid response to calls for consultation are all important  evaluation of vaginal or surgical site bleeding  obstetric sources of infection,  therapies (such as magnesium for eclampsia prophylaxis),  surgical issues, such as re-exploration of the abdomen or reclosure of abdominal and perineal or vaginal incisions. Role of the Obstetrician–Gynecologist Regardless of the type of ICU
  • 26.  The underpinning principles are that the woman’s interests are paramount, and optimal fetal status is generally predicated on optimizing the maternal condition as much as possible.  Medical interventions and diagnostic imaging may be modified to an extent but when indicated for maternal health should not be withheld purely for fetal concerns.  It is important not to discourage ICU admission; rather, encouraged to use critical care services when appropriate Role of the Obstetrician–Gynecologist Regardless of the type of ICU
  • 27. Maternal stabilization is the first priority  Once woman is stable, determine GA to plan of care, immediate decision-making.  Drugs that cross the placenta may have fetal effects  Known adverse effects on the woman and the fetus must be carefully monitored, and risk–benefit ratios assessed Neither necessary medications nor diagnostic imaging should be withheld from a pregnant woman because of fetal concerns. Special considerations in care of a pregnant woman in a critical care setting
  • 28.  Administration of steroids for fetal benefit  Indicated delivery should not be delayed for administration of steroids in the late preterm period  Fetal monitoring  In postpartum period, obstetricians should evaluate vaginal or surgical site bleeding, therapies, surgical issues  Provision of lactation support and a breast pump may also be considered when feasible. special considerations in care of a pregnant woman in a critical care setting
  • 32. Mechanical ventilation Sedation  Vasopressors  hemodynamic monitoring SUPPORTIVE CARE  Defined as interventions that sustain life and prevent complications, but do not treat the cause of the critical illness
  • 33.  Normal physiology, pregnancy maintain respiratory alkalosis (PaCO2 32 mmHg and arterial pH 7.4 to 7.47) due to respiratory stimulation by progesterone  Mechanical ventilation is similar for pregnant and non- pregnant women  The major pregnancy-specific considerations are related PaCO2. Target PaCO2 should be 30 to 32 mmHg  PaCO2 values <30 mmHg or >40 mmHg to be avoided  A reasonable goal is a maternal PaO2 above 65 mmHg Mechanical ventilation
  • 34.  Intubation and mechanical ventilation are undertaken when hypoxemia is profound and cannot be corrected by noninvasive means, or when ventilation is failing  Airway management in pregnancy can be challenging  Increased airway edema and increased breast size make positioning and direct laryngeal visualization more difficult.  The risk of failed intubation in obstetrics is eight times higher than in the general population  Once the decision to intubate is made, the patient should be preoxygenated and suction should be available; the most qualified personavailable should intubate.  A plan for failed intubation must be made ahead of time, Mechanical Ventilation
  • 35.  Interventions other than vasopressors should be used initially to manage hypotension, including the IV fluids and left lateral decubitus position.  If Hypotension persists initiate vasopressor, since sustained hypotension decreases uterine blood flow.  For pregnant women, suggest norepinephrine as the initial agent, rather than ephedrine, epinephrine or dopamine (Grade 2C).  If refractory shock , suggest the use of phenylephrine rather than ephedrine (Grade 2C) Vasopressors
  • 36.  Most drugs used for analgesia, sedation, and paralysis cross the placenta >>>>>> Possible adverse effects  Consultation with an obstetrician and a pharmacist  A neonatologist should be present at delivery because may respiratory depression in the newborn  Analgesia: Any opioid is acceptable. However, NSAIDs should be avoided during late pregnancy  Sedation: * Midazolam is superior to lorazepam * Propofol classified as a pregnancy category B agent.  Neuromuscular blocker: Cisatracurium may be preferable as a first line agent Sedation
  • 37. All patients should undergo conventional ICU monitoring.  Invasive hemodynamic monitoring especially when hypoxemic respiratory failure (pulmonary edema) accompanied by hypotension and/or renal failure.  Using a central venous catheter to measure the central venous pressure, rather than a pulmonary artery catheter Arterial catheter if BP is labile or frequent ABG needed Hemodynamic monitoring
  • 45. 09- Jul-18 Dr Shashwat Jani. +919909944160. 63