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Development, manufacturing and sales of
game changing wound dressings and plasters
NAPOLY LLC was founded in April 2014
Founders: Seed Fund RVC, Biotechfarm CJSC, MSU Science Park and individuals
Product: ChitoPran® wound dressing
Registration certificate: № 2012/14071 dated August 26, 2014
Patent in Russia: № 252216
Manufacturing: Techno park Strogino & NPM CJSC, full manufacturing cycle in
Russia
Production capacity: 30 mln. items per year
NAPOLY LLC owns the Moscow innovational passport № 301
Current stage : sale
 Tender activities in order to supply its products to the various medical clinics
and hospitals throughout the territory of Russia;
 Pharmacies in Russia;
 On-line store.
Summary
2
 complex effect on wound
 no need to remove
 reduction of toxicity
New progressive approach to
management of the wounds
A human hair (80 microns) on the left and
pollen (30 microns) on the right on a
background of material of nanofibers (100 nm)
 the biological activity of chitosan
 nanofibrous layer structure
 additional biological effect of drugs
 high bioavailability of drug substances
Uniqueness
3
Product
ChitoPran® - indications for use:
 Treatment of torn, punctured,
incised wounds.
 Treatment of sluggish
granulating wounds, nonhealing
wounds in the step of regeneration,
burns II - III degrees, trophic ulcers, bedsores, frostbite.
 Temporary closure of burn wounds of IIIb degree to prepare them for
autodermoplasty.
 Closing of donor sites.
 Closing of capillary bleeding sections .
 Bedsores in places of pressing dentures.
 During the circumcision.
 Children's wards in clinics and hospitals. 4
5
Official papers
Registration Certificate of
Medical Product
Patent in Russia
6
Manufacturing technology
Submicron fibers in the form of ribbons
Administering the antibiotic
in the spinning solution
ELECTRO-
SPINNING
STERILIZATION
THERMO
PROCESSING
Increasing of strength
Timing control of dissolution
Radiation
Clinical observations
Dynamics of a donor wound healing using ChitoPran®
1) Donor wound 2) Imposition of biocover
3) Donor wound after 13 days
Donor wound,
male, 25 years
7
More than 80
distributors in Russia
Full cycle
Medical clinics, hospitals Pharmacies
MANUFACTURING
SALE
Individuals
Own system of
distribution
NAPOLY’s
on-line store
Business model
Wholesale
8
KATREN
- 19,9 mln.rub.
37,5 mln.rub.
(30 000 000)
(15 000 000)
-
15 000 000
30 000 000
45 000 000
1 кв.14 1 кв.15 1 кв.16 1 кв.17 1 кв.18
Выручка Расходы Прибыль накопленным итогом
Payback period = 4 years
Financial plan
Profit accumulatedRevenue Expenses
9
-30
-10
10
30
50
0 1 2 3 4 5 6 7
Traditional funds
Billion, $
Global market - $12 billion
Marketgrowth,%
Modern dressings / coating
Antimicrobial dressings
An increase of 30% per year
International market place dressings
ChitoPran®
10
11
Competitors
WHO?
WHEN? After coverage of the Russian and
CIS markets, 2018
Ivan Afanasov
Ph.D., Co-owner
Our team
Tatiana Yudanova
D.Sc., developer
Sergey Brusov
CEO
Olga Titova
Developer, promoter
Dmitry Perminov
Co-owner
Oleg Kareev
EU and SEA customer
development manager
12

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NAPOLY LLC

  • 1. Development, manufacturing and sales of game changing wound dressings and plasters
  • 2. NAPOLY LLC was founded in April 2014 Founders: Seed Fund RVC, Biotechfarm CJSC, MSU Science Park and individuals Product: ChitoPran® wound dressing Registration certificate: № 2012/14071 dated August 26, 2014 Patent in Russia: № 252216 Manufacturing: Techno park Strogino & NPM CJSC, full manufacturing cycle in Russia Production capacity: 30 mln. items per year NAPOLY LLC owns the Moscow innovational passport № 301 Current stage : sale  Tender activities in order to supply its products to the various medical clinics and hospitals throughout the territory of Russia;  Pharmacies in Russia;  On-line store. Summary 2
  • 3.  complex effect on wound  no need to remove  reduction of toxicity New progressive approach to management of the wounds A human hair (80 microns) on the left and pollen (30 microns) on the right on a background of material of nanofibers (100 nm)  the biological activity of chitosan  nanofibrous layer structure  additional biological effect of drugs  high bioavailability of drug substances Uniqueness 3
  • 4. Product ChitoPran® - indications for use:  Treatment of torn, punctured, incised wounds.  Treatment of sluggish granulating wounds, nonhealing wounds in the step of regeneration, burns II - III degrees, trophic ulcers, bedsores, frostbite.  Temporary closure of burn wounds of IIIb degree to prepare them for autodermoplasty.  Closing of donor sites.  Closing of capillary bleeding sections .  Bedsores in places of pressing dentures.  During the circumcision.  Children's wards in clinics and hospitals. 4
  • 5. 5 Official papers Registration Certificate of Medical Product Patent in Russia
  • 6. 6 Manufacturing technology Submicron fibers in the form of ribbons Administering the antibiotic in the spinning solution ELECTRO- SPINNING STERILIZATION THERMO PROCESSING Increasing of strength Timing control of dissolution Radiation
  • 7. Clinical observations Dynamics of a donor wound healing using ChitoPran® 1) Donor wound 2) Imposition of biocover 3) Donor wound after 13 days Donor wound, male, 25 years 7
  • 8. More than 80 distributors in Russia Full cycle Medical clinics, hospitals Pharmacies MANUFACTURING SALE Individuals Own system of distribution NAPOLY’s on-line store Business model Wholesale 8 KATREN
  • 9. - 19,9 mln.rub. 37,5 mln.rub. (30 000 000) (15 000 000) - 15 000 000 30 000 000 45 000 000 1 кв.14 1 кв.15 1 кв.16 1 кв.17 1 кв.18 Выручка Расходы Прибыль накопленным итогом Payback period = 4 years Financial plan Profit accumulatedRevenue Expenses 9
  • 10. -30 -10 10 30 50 0 1 2 3 4 5 6 7 Traditional funds Billion, $ Global market - $12 billion Marketgrowth,% Modern dressings / coating Antimicrobial dressings An increase of 30% per year International market place dressings ChitoPran® 10
  • 11. 11 Competitors WHO? WHEN? After coverage of the Russian and CIS markets, 2018
  • 12. Ivan Afanasov Ph.D., Co-owner Our team Tatiana Yudanova D.Sc., developer Sergey Brusov CEO Olga Titova Developer, promoter Dmitry Perminov Co-owner Oleg Kareev EU and SEA customer development manager 12