PRP ( Platelet Rich Plasma ) is a Autologous blood which contains platelets higher than normal.
Normal platelet count is 4.5 × 105/μL, but PRP has 4–5 times the normal value.
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Prp injections in orthopedics
1. PRP INJECTIONS IN ORTHOPEDICS
What is PRP?
PRP ( Platelet Rich Plasma ) is a Autologous blood which contains platelets higher than normal.
Normal platelet count is 4.5 × 105/μL, but PRP has 4–5 times the normal value.
How does PRP work?
Platelets secrete growth factors like platelet-derived growth factor (PDGF), transforming growth
factor beta (TGF-β), vascular endothelial growth factor (VEGF), and epithelial growth factor (EGF)
which improves healing process.
Platelets also have adhesion molecules like fibrin, fibronectin, and vitronectin which promote
bone formation.
2. How is PRP prepared?
Patient’s own blood drawn is then centrifuged in a machine to separate platelets. This
centrifugation allows the separation and collection of the buffy coat layer that contains PRP.
This prepared PRP is then administered to the site of injury or into the joints.
What are the conditions treated with PRP?
3. Do we need to be admitted in the hospital for PRP
procedure?
It’s a day care procedure done in the out patient department, you will be send home
immediately after the procedure.
How long we need to take rest after the procedure?
Technically there in no need for rest but it’s advisable for 24 – 48 hrs of less activity to be on
safer side.
How painful is the PRP injection?
It’s not a painful procedure on a scale of 10 it’s just 1.
X
4. What are it’s side effects?
As PRP is prepared from your blood it doesn’t have any side effects, It’s 100% safer procedure.
How long does it take PRP to act?
Usually it takes around 3-4 weeks .
How long does PRP work?
It depends on the magnitude of the problem, at what stage the PRP is administered and also varies from person
to person.
How many PRP injections are needed?
It depends on chronicity and the magnitude of the problem, varies from 1 – 3 injections given at 3 – 4 week
intervals.