Dr Simon Schultz: Nesta Hot Topics Prostethics and Bionics slides

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To watch Dr Simon Schultz giving this presentation visit http://www.nesta.org.uk/events/hot_topics/assets/topics/prosthetics_and_bionics

Technology

New dimensions on
neuroprosthetics
Simon Schultz
Imperial College London

A long term view

Reading out neuronal activity
• e.g. ratiometric calcium sensor YC3.60

Lutcke et al Frontiers in Neural Circuits 2010

Of Cre mice and men

Cre driver lines

From O’Connor Nature 2009

Writing brain signals

Channelrhodopsin-2 (ChR2)
Deisseroth, Boyden

Erasing brain signals

AAV-CAG-ArchT-GFP, NeuroTrace

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