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Case presentation
Data:
• Mrs. Renuka
• 42/F
• Occupation :House maid
Chief complaints: HOPI
- Fever * 3 days
- Dry cough * 3 days
- Breathlessness since yesterday night.
Patient was apparently normal three days back & she developed fever which is low
grade, continuous type associated with cough which is dry not continuous not blood
stained and not associated with chills/rigor. After that She developed
breathlessness[MMRC III] since the night before ER Presentation, which was
progressive in nature and worsened since today morning. No relieving factor. H/o
generalized tiredness (+). H/o decrease urine output (~ 100 -200 ml)since yesterday
night.
HOPI:
Negative history:
• No h/o vomiting ,loose stools, chest pain, burning
micturation,hematuria abdominal pain, giddiness, altered sensorium.
• No recent travel history.
• TB contact/loss of weight/loss of appetite/bleed/rashes/ joint
pain/swelling
Adayar clinic – initially presented to adayar kmh treated with
inj.hydrocortisone, nebulisers, IV fluids 1.5 litres and NIV support and
shifted with inotropes support
PAST HISTORY:
• RA FACTOR positive - 1 MONTH back. PATIENT started ON
T.ETORICOXIB & T.PREDINISOLONE DAILY.
• Routine neg.
GENERAL EXAMINATION:
• CONSCIOUS,ORIENTED. GCS – 15/15.
• FEBRILE – 101.2 F
• TACHYPNEIC
• NO PALLOR ,ICTERUS,CYANOSIS,CLUBBING,LYMPHADENOPATHY,EDEMA
• VITALS: BP -100/80 MMHG with 3ml/hr noradrenaline support .(taken on right
arm sitting position)
• PR- 124/MIN
SPO2 – 85 -92 @ 15 L 02
RR – 31/MIN
Systemic examination: Respiratory system
• Inspection: Trachea is in midline, Chest is symmetrical, no chest wall
deformity,movement of chest is equal in both sides &
normal,Abdominal thoraco breathing,Tachypneic,using accessory
muscles for respiration. No dilated or engorged veins, No
scars,swelling & visible pulsation seen.
• Palpation: Not done.
• Auscultation: bilateral extensive crepitation in all areas of chest.
• Percussion: Dull in all areas of chest..
SUMMARY:
• 42 YR/F CAME WITH C/O FEVER(D3), BREATHLESSNESS AT REST , DECREASE URINE
OUTPUT, GENERALISED TIREDNESS. WHILE RECEIVING PATIENT WAS FEBRILE &
TACHYPENIC , WHEEZE + .
• PATIENT WAS INTIALLY EVALUATED AT KMH ADAYAR . STARTED ON
NIV.WORSENING SHORTNESS OF BREATH AND DIFFICULTY IN LYING DOWN FLAT.
PATIENT WAS COUNSELLED FOR ICU ADMISSION AND SHIFTED TO KAMAKSHI ER
FOR FURTHER MANAGEMENT.
• INITIALLY STARTED WITH NEBULISERS 2 CYCLES, IV PARACETAMOL 1GM IV,
INJ.HYDROCORT 100 MG IV, IV FLUIDS 1000ML IV BOLUS F/B 200ML/HR.
• NIL URINE OUTPUT .
• BP WAS NOT MAINTAINED.STARTED INJ.NORADRENALINE 8ML/HR.
• PATIENT DEVELOPED B/L CREPTS+.
Investigations:
• ABG: PaO2/FIO2 RATIO  < 100
• ECG –
• XRAY – B/L UPPER & MIDDLE ZONE INFILTRATES +. F/S/O SEVERE
ARDS.
• ECHO – LVEF 65% ,NO RWMA, NORMAL LV, IVC – COLLAPSING.
Provisional DIAGNOSIS:
• Influenza like illness / CAP
• Severe ARDS
• Septic shock
• RA positive on Steroid tx
Treatment:
• IN VIEW OF IMPENDING RESPIRATORY DISTRESS , PATIENT INTUBATED WITH
7MM ET TUBE FIXED AT LIP LEVEL 22 CM WITH
• PREMEDICATION: INJ.SCOLINE 100MG, INJ.KETAMINE 100MG, INJ.FENTANYL
100MG. 5 POINTS AUSCULATION CHECKED.
• VCV MODE : FIO2 100 % PEEP -12 TV – 420
• POST PROCEDURE VITALS: SPO2 – 92 % BP – 130/70 MMHG PR – 120/min
• INJ.NORADRENALINE 5 ML/HR
• ANTIBIOTICS : INJ.MEROPENAM 2GM IV STAT.
• Catheterization :10ML URINE OUTPUT.
• IV fluids 100ml /hr
• Right ijv central line secured.
BUFALO
Summarize : only positibe
ICU CARE:
• PATIENT REVIEWED BY ICU TEAM  IN VIEW OF Refractory HYPOXIA(84-87%) - PRONE
VENTILATION.
• Repeat ABG - ?? RESPIRATORY ACIDOSIS WITH HIGH LACTATE.
• A LINE secured at right radial
• I/V/O PERSISTENT HYPOTENSION  INJ.NORADRENALINE uptitrated AND VASOPRESSIN
SUPPORT STARTED.
• BLOOD REPORTS REVIEWED  leukocytosis
• Antibiotic :INJ.MEROPENAM 1GM TDS , INJ.TEICOPLANIN 400MG BD, T.AZITHROMYCIN
5OOMG 1-O-O , T.OSELTAMAVIR 75 MG 1-0-1 .
• INJ.HYDROCORTISONE 50MG 1-0-1
• INJ.CLEXANE 60MG S/C O for prophylaxis.
DAY 2:
• I/V/O PERSISTANT HYPOTENSION AND LACTIC ACIDOSIS . PATIENT
ATTENDERS WAS EXPLAINED IN DETAIL ABOUT ECMO TO IMPROVE
OXYGENATION.
• CTVS OPINION OBTAINED  PATIENT WAS UNPRONED AFTER 16HRS
OF PRONE VENTILATION AND VenoVenous ECMO WAS PLACED
UNDER ASPETIC PRECAUTION.
• VCV MODE FIO2 : 100% SERIAL ABG WAS MONITORED
WORSENING ACIDOIS AND LACTATE LEVELS.
• PATIENT ON MAXED OUT INOTROPES LEVELS.
DAY 2:
• PATIENT WAS ANURIC WITH SERIAL INCREASE IN LACTATE LEVELS.
CONTINUOUS RENAL REPLACEMENT DIALYSATE 800ML/POST 600ML)
THERAPY WAS INITIATED.( AT EFFLUENT RATE OF 1800 ML, PRE
400ML
• DAY 3 PATIENT ON MAX INOTROPES SUPPORT UNDER SEDATION &
PARALYSIS SHE WAS HYPOTENSIVE,BRADYCARDIA AND HYPOXIA.
• DESPITE ALL RESUSCIATIVE MEASURE WITH ALL SUPPORTIVE
MEDICATION.
• PATIENT DETORIATES AND DECLARED DEAD.
ARDS /Prone ventilation/ECMO
ON ARRIVAL: @ ER:
• SHE IS TACHYPNEIC,GCS- 15/15.
• RR- 36/MIN
• BP- 100/60 @ 3ML INJ.NORADRENALINE 3ML/HR.
• SPO2 – 85 @ 15 L O2
RS:
• Inspection/palp -
• ON AUSCULTATION B/L CREpTS – areas , nvbs/bronch, accessory muscle usage, other
added sounds
• Percussion
• cvs

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Case presentation ARDS.pptx

  • 2. Data: • Mrs. Renuka • 42/F • Occupation :House maid
  • 3. Chief complaints: HOPI - Fever * 3 days - Dry cough * 3 days - Breathlessness since yesterday night. Patient was apparently normal three days back & she developed fever which is low grade, continuous type associated with cough which is dry not continuous not blood stained and not associated with chills/rigor. After that She developed breathlessness[MMRC III] since the night before ER Presentation, which was progressive in nature and worsened since today morning. No relieving factor. H/o generalized tiredness (+). H/o decrease urine output (~ 100 -200 ml)since yesterday night. HOPI:
  • 4. Negative history: • No h/o vomiting ,loose stools, chest pain, burning micturation,hematuria abdominal pain, giddiness, altered sensorium. • No recent travel history. • TB contact/loss of weight/loss of appetite/bleed/rashes/ joint pain/swelling Adayar clinic – initially presented to adayar kmh treated with inj.hydrocortisone, nebulisers, IV fluids 1.5 litres and NIV support and shifted with inotropes support
  • 5. PAST HISTORY: • RA FACTOR positive - 1 MONTH back. PATIENT started ON T.ETORICOXIB & T.PREDINISOLONE DAILY. • Routine neg.
  • 6. GENERAL EXAMINATION: • CONSCIOUS,ORIENTED. GCS – 15/15. • FEBRILE – 101.2 F • TACHYPNEIC • NO PALLOR ,ICTERUS,CYANOSIS,CLUBBING,LYMPHADENOPATHY,EDEMA • VITALS: BP -100/80 MMHG with 3ml/hr noradrenaline support .(taken on right arm sitting position) • PR- 124/MIN SPO2 – 85 -92 @ 15 L 02 RR – 31/MIN
  • 7. Systemic examination: Respiratory system • Inspection: Trachea is in midline, Chest is symmetrical, no chest wall deformity,movement of chest is equal in both sides & normal,Abdominal thoraco breathing,Tachypneic,using accessory muscles for respiration. No dilated or engorged veins, No scars,swelling & visible pulsation seen. • Palpation: Not done. • Auscultation: bilateral extensive crepitation in all areas of chest. • Percussion: Dull in all areas of chest..
  • 8. SUMMARY: • 42 YR/F CAME WITH C/O FEVER(D3), BREATHLESSNESS AT REST , DECREASE URINE OUTPUT, GENERALISED TIREDNESS. WHILE RECEIVING PATIENT WAS FEBRILE & TACHYPENIC , WHEEZE + . • PATIENT WAS INTIALLY EVALUATED AT KMH ADAYAR . STARTED ON NIV.WORSENING SHORTNESS OF BREATH AND DIFFICULTY IN LYING DOWN FLAT. PATIENT WAS COUNSELLED FOR ICU ADMISSION AND SHIFTED TO KAMAKSHI ER FOR FURTHER MANAGEMENT. • INITIALLY STARTED WITH NEBULISERS 2 CYCLES, IV PARACETAMOL 1GM IV, INJ.HYDROCORT 100 MG IV, IV FLUIDS 1000ML IV BOLUS F/B 200ML/HR. • NIL URINE OUTPUT . • BP WAS NOT MAINTAINED.STARTED INJ.NORADRENALINE 8ML/HR. • PATIENT DEVELOPED B/L CREPTS+.
  • 9. Investigations: • ABG: PaO2/FIO2 RATIO  < 100 • ECG – • XRAY – B/L UPPER & MIDDLE ZONE INFILTRATES +. F/S/O SEVERE ARDS. • ECHO – LVEF 65% ,NO RWMA, NORMAL LV, IVC – COLLAPSING.
  • 10.
  • 11. Provisional DIAGNOSIS: • Influenza like illness / CAP • Severe ARDS • Septic shock • RA positive on Steroid tx
  • 12. Treatment: • IN VIEW OF IMPENDING RESPIRATORY DISTRESS , PATIENT INTUBATED WITH 7MM ET TUBE FIXED AT LIP LEVEL 22 CM WITH • PREMEDICATION: INJ.SCOLINE 100MG, INJ.KETAMINE 100MG, INJ.FENTANYL 100MG. 5 POINTS AUSCULATION CHECKED. • VCV MODE : FIO2 100 % PEEP -12 TV – 420 • POST PROCEDURE VITALS: SPO2 – 92 % BP – 130/70 MMHG PR – 120/min • INJ.NORADRENALINE 5 ML/HR • ANTIBIOTICS : INJ.MEROPENAM 2GM IV STAT. • Catheterization :10ML URINE OUTPUT. • IV fluids 100ml /hr • Right ijv central line secured.
  • 14. Summarize : only positibe
  • 15.
  • 16. ICU CARE: • PATIENT REVIEWED BY ICU TEAM  IN VIEW OF Refractory HYPOXIA(84-87%) - PRONE VENTILATION. • Repeat ABG - ?? RESPIRATORY ACIDOSIS WITH HIGH LACTATE. • A LINE secured at right radial • I/V/O PERSISTENT HYPOTENSION  INJ.NORADRENALINE uptitrated AND VASOPRESSIN SUPPORT STARTED. • BLOOD REPORTS REVIEWED  leukocytosis • Antibiotic :INJ.MEROPENAM 1GM TDS , INJ.TEICOPLANIN 400MG BD, T.AZITHROMYCIN 5OOMG 1-O-O , T.OSELTAMAVIR 75 MG 1-0-1 . • INJ.HYDROCORTISONE 50MG 1-0-1 • INJ.CLEXANE 60MG S/C O for prophylaxis.
  • 17. DAY 2: • I/V/O PERSISTANT HYPOTENSION AND LACTIC ACIDOSIS . PATIENT ATTENDERS WAS EXPLAINED IN DETAIL ABOUT ECMO TO IMPROVE OXYGENATION. • CTVS OPINION OBTAINED  PATIENT WAS UNPRONED AFTER 16HRS OF PRONE VENTILATION AND VenoVenous ECMO WAS PLACED UNDER ASPETIC PRECAUTION. • VCV MODE FIO2 : 100% SERIAL ABG WAS MONITORED WORSENING ACIDOIS AND LACTATE LEVELS. • PATIENT ON MAXED OUT INOTROPES LEVELS.
  • 18.
  • 19. DAY 2: • PATIENT WAS ANURIC WITH SERIAL INCREASE IN LACTATE LEVELS. CONTINUOUS RENAL REPLACEMENT DIALYSATE 800ML/POST 600ML) THERAPY WAS INITIATED.( AT EFFLUENT RATE OF 1800 ML, PRE 400ML
  • 20.
  • 21. • DAY 3 PATIENT ON MAX INOTROPES SUPPORT UNDER SEDATION & PARALYSIS SHE WAS HYPOTENSIVE,BRADYCARDIA AND HYPOXIA. • DESPITE ALL RESUSCIATIVE MEASURE WITH ALL SUPPORTIVE MEDICATION. • PATIENT DETORIATES AND DECLARED DEAD.
  • 23. ON ARRIVAL: @ ER: • SHE IS TACHYPNEIC,GCS- 15/15. • RR- 36/MIN • BP- 100/60 @ 3ML INJ.NORADRENALINE 3ML/HR. • SPO2 – 85 @ 15 L O2 RS: • Inspection/palp - • ON AUSCULTATION B/L CREpTS – areas , nvbs/bronch, accessory muscle usage, other added sounds • Percussion • cvs