what you can do to prevent Alzheimer’s? Hello, I am Mohammad Seder from Hebron in Palestine, I’m going to talk about what you can do to prevent Alzheimer’s. This scary disease, despite decades of research, scientists still have no cure of this disease. Firstly, let’s begin by looking at what the scientists currently understand about the neuroscience of Alzheimer's, and we will then talk about how to prevent it. Here’s a picture of two neurons connecting, the point of connection the space circled in red is called the synapse. The synapses where neurotransmitters are released, this where signals are transmitted or communication happens, this is where we think, feel, see, desire, and remember. But in the synapses where the Alzheimer happen, during the business of communicating information, Neurons released small peptide called amyloid-beta. And most scientists believe that, the disease begins when amyloid-beta begins to accumulate, and when this happens it binds to itself forming sticky aggregates called amyloid-beta plaques. Scientists think it takes at least 15 to 20 years of amyloid plaque accumulation before it causes the clinical symptoms of Alzheimer. High blood pressure, diabetes, obesity, smoking have all been shown to increase our risk of developing Alzheimer's. In deep sleep, spinal fluid throughout our brains clearing away metabolic waste that accumulated in our synapses while we were awake. Aerobic exercises has been many studies to decrease amyloid-beta. But there's one more thing you can do to protect yourself from experiencing the symptoms of Alzheimer's. Remember the experience of having Alzheimer's is due to a result of losing synapses. Let's imagine a simplified example, let's say you only know one thing about a subject, let's say it's about me, you know that, Mohmmad studies at PPU, and that's the only thing you know about me. You have that single neural connection that one synapse. now imagine you have Alzheimer's plaques. you can't remember because you forgotten me forever. But what if you have learned more about me, let’s say you also know that’ I am study medicine, I live in Hebron, I am study at PPU, and I am a neuroscientist for example. Alzheimer's in three of these synapses are damaged, but you still have a way to bypass the remain information, so you can still remember my name. So, in short, we can be resistant to the presence of Alzheimer's pathology through the employment of undamaged pathways. You want to pave new neural roads building. So, in my opinion Alzheimer's resistant brain means keeping your brain learning and learning about new experiences , such as learning to speak a new language, meeting new friends, or reading a book or deeply thinking in the Holy Qur'an. And THANK YOU

1. ALZEHIMER’S (AD)
what you can do to prevent Alzehimer's ?
MOHMMADRJAB S. SEDER

2. Overview
- Neuroscience of Alzheimer's
- How to prevent it

3. Synapse

5. Amyloid-Beta

6. 15-20
YEARS

7. 1. High blood pressure
2. Diabetes
3. Obesity
4. Smoking

8. Sleeping !

10. !!!

11. Studies
at PPU
MohmmadRjab
Seder

16. Thank you