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Clinical Skills
Workshop:
Overdose Prevention and Response —
Administering Naloxone to Save Lives
Conflict of Interest Disclaimer
 No financial disclosures.
 Adapt Pharma provided one trainer of its nasal spray (no medicine) for
demonstration.
 Kaleo provided Evzio autoinjectable trainers (no medicine) for
demonstration.
National Overdose Deaths
Number of Deaths from Prescription Drugs
0
5,000
10,000
15,000
20,000
25,000
30,000 Total Female Male
Source: National Center for Health Statistics, CDC Wonder
National Overdose Deaths
Number of Deaths from Prescription Opioid Pain Relievers
0
2,000
4,000
6,000
8,000
10,000
12,000
14,000
16,000
18,000
20,000 Total Female Male
Source: National Center for Health Statistics, CDC Wonder
National Overdose Deaths
Number of Deaths from Heroin
0
2,000
4,000
6,000
8,000
10,000
12,000 Total Female Male
Break for video #1
It’s more than “use as directed”
An adverse reaction can occur if:
 Co-morbidities: lungs, liver, kidneys, etc.
 Co-pharmacy: e.g. sedative
 Genetic susceptibility
 Drinking alcohol
 User error
 Period of abstinence
 Switching opioids
 Family member may help themselves
When to write a script
 If patient is prescribed an opioid medication
 If patient is using opioids of any kind
 After a period of abstinence (any kind, including incarceration or drug
treatment)
 If pt. has experienced an overdose or adverse reaction.
 If pt. has witnessed an overdose or adverse reaction.
 If pt. asks for it.
 If pt. has a household member who might benefit from it.
Break for video #2
Enabling? No!
Safe? Yes!
• Been around since 1961
• Communities have been distributing
since 1996
• No compensatory behavior since it
causes withdrawal.
• No potential for abuse.
• People use it.
• Leads to treatment for substance
use disorder.
• Decrease in deaths much greater
than amount supplied, indicating
decrease in risky behavior as result
of the educational process that is
part of providing rx.
Rx, OTC, Standing Order
To script or not to script
 There may not be a standing order in your state
 Standing order may only be for certain pharmacies
 Pharmacist may not be aware of standing order
 Patient may not remember to ask for it
 Easier to pick up all rx at once
 Less worry about payment and billing issues
 There is no downside to writing a script
Your new best friend:
www.prescribetoprevent.org
One-stop shopping for patients, advocates, prescribers, pharmacists: videos,
online CME, research, legal info, billing, Rx pads, and things you never thought
you might need.
 Where do we go from here?
 Train your classmates: this is an easy brown-bag lunch session.
 Show video(s)
 Give demo
 Tell people where to get it for themselves
 Make this a national AMSA Project, educating medical students, college
students, incarcerated populations, drug treatment programs, faith
communities, etc.
Thank you!
Mary Beth Levin, MPH
Associate Professor
Department of Family Medicine
Georgetown University School of Medicine
levinmb@gmail.com
Other resources:
Harm Reduction Coalition: www.harmreduction.org
North Carolina Harm Reduction Coalition: www.nchrc.org
Chicago Recovery Alliance: www.anypoisitivechange.org

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Clinical Skills Workshop

  • 1. Clinical Skills Workshop: Overdose Prevention and Response — Administering Naloxone to Save Lives
  • 2. Conflict of Interest Disclaimer  No financial disclosures.  Adapt Pharma provided one trainer of its nasal spray (no medicine) for demonstration.  Kaleo provided Evzio autoinjectable trainers (no medicine) for demonstration.
  • 3.
  • 4. National Overdose Deaths Number of Deaths from Prescription Drugs 0 5,000 10,000 15,000 20,000 25,000 30,000 Total Female Male Source: National Center for Health Statistics, CDC Wonder
  • 5. National Overdose Deaths Number of Deaths from Prescription Opioid Pain Relievers 0 2,000 4,000 6,000 8,000 10,000 12,000 14,000 16,000 18,000 20,000 Total Female Male Source: National Center for Health Statistics, CDC Wonder
  • 6. National Overdose Deaths Number of Deaths from Heroin 0 2,000 4,000 6,000 8,000 10,000 12,000 Total Female Male
  • 8.
  • 9. It’s more than “use as directed” An adverse reaction can occur if:  Co-morbidities: lungs, liver, kidneys, etc.  Co-pharmacy: e.g. sedative  Genetic susceptibility  Drinking alcohol  User error  Period of abstinence  Switching opioids  Family member may help themselves
  • 10.
  • 11. When to write a script  If patient is prescribed an opioid medication  If patient is using opioids of any kind  After a period of abstinence (any kind, including incarceration or drug treatment)  If pt. has experienced an overdose or adverse reaction.  If pt. has witnessed an overdose or adverse reaction.  If pt. asks for it.  If pt. has a household member who might benefit from it.
  • 12.
  • 14.
  • 15. Enabling? No! Safe? Yes! • Been around since 1961 • Communities have been distributing since 1996 • No compensatory behavior since it causes withdrawal. • No potential for abuse. • People use it. • Leads to treatment for substance use disorder. • Decrease in deaths much greater than amount supplied, indicating decrease in risky behavior as result of the educational process that is part of providing rx.
  • 17. To script or not to script  There may not be a standing order in your state  Standing order may only be for certain pharmacies  Pharmacist may not be aware of standing order  Patient may not remember to ask for it  Easier to pick up all rx at once  Less worry about payment and billing issues  There is no downside to writing a script
  • 18. Your new best friend: www.prescribetoprevent.org One-stop shopping for patients, advocates, prescribers, pharmacists: videos, online CME, research, legal info, billing, Rx pads, and things you never thought you might need.  Where do we go from here?  Train your classmates: this is an easy brown-bag lunch session.  Show video(s)  Give demo  Tell people where to get it for themselves  Make this a national AMSA Project, educating medical students, college students, incarcerated populations, drug treatment programs, faith communities, etc.
  • 19. Thank you! Mary Beth Levin, MPH Associate Professor Department of Family Medicine Georgetown University School of Medicine levinmb@gmail.com Other resources: Harm Reduction Coalition: www.harmreduction.org North Carolina Harm Reduction Coalition: www.nchrc.org Chicago Recovery Alliance: www.anypoisitivechange.org

Editor's Notes

  1. National Overdose Deaths—Number of Deaths from Prescription Drugs. The figure above is a bar chart showing the total number of U.S. overdose deaths involving prescription drugs from 2001 to 2014. The chart is overlayed by a line graph showing the number of deaths by females and males. From 2001 to 2014 there was a 2.8-fold increase in the total number of deaths.
  2. National Overdose Deaths—Number of Deaths from Prescription Opioid Pain Relievers. The figure above is a bar chart showing the total number of U.S. overdose deaths involving opioid pain relievers from 2001 to 2014. The chart is overlayed by a line graph showing the number of deaths by females and males. From 2001 to 2014 there was a 3.4-fold increase in the total number of deaths.
  3. National Overdose Deaths—Number of Deaths from Heroin. The figure above is a bar chart showing the total number of U.S. overdose deaths involving heroin from 2001 to 2014. The chart is overlayed by a line graph showing the number of deaths by females and males. From 2001 to 2014 there was a 6-fold increase in the total number of deaths.