1. Marta V. Hamity, Ph.D.
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CURRICULUM VITAE
Marta V. Hamity, Ph.D.
Department of Anesthesia
3000 Medical Laboratories
University of Iowa
Iowa City, IA
(319) 384-4481 (office)
(319) 594-5048 (cell)
marta-hamity@uiowa.edu
EDUCATION
1997-2002 Bachelor of Science (Psychology). Universidad Nacional de Cordoba,
Argentina.
 Degree thesis “Development of a behavioral test in the rat to evaluate
muscle pain produced by physiologic pain substances” Grade: 10 (ten),
Summa Cum Laude. August 2002
2003-2007 PhD in Psychology, Universidad Nacional de Córdoba, Argentina.
 PhD Thesis: “Pain sensibility mediated by neurons that depend on
specific trophic factors during development”. Grade: 10 (ten), Summa
Cum Laude. December, 2007.
RESEARCH EXPERIENCE
Assistant Research Scientist, May 2012 to present. Department of Anesthesia,
University of Iowa. Mentor: Donna L. Hammond, Ph.D.
 Project: Nicotinamide Ribose as a novel treatment for peripheral
neuropathies.
 Responsible for grant writing, the design and conduct of the experiments,
graphic presentation and statistical analysis of the data, preparation of
manuscripts and data presentation in lab meetings and international meetings
 Responsible for supervision of undergraduate and graduate students
 Techniques:
 Measurement of pain behaviors in the conscious laboratory rodent
o Von Frey test filaments to measure mechanical nociception
o Hargreaves test for thermal nociception
o Assessment of Cold Allodynia.
o Assessment of pain aversiveness using the Place Escape Avoidance
Paradigm (PEAP)
 Brain, dorsal root ganglia, spinal cord and skin tissue dissections from rat.
 RNA isolation, RT-PCR and qPCR
 Light, epifluorescence and confocal microscopy
 Single, double and triple-label immunohistochemical methods
 Quantitative analysis of immunohistochemical data using Autoneuron and
StereoInvestigator image analysis software.

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Postdoctoral Scholar, January 2008 to May 2012; Department of Anesthesia,
University of Iowa. Mentor: Donna L. Hammond, Ph.D.
 Project: Study the role of Substance P and the neurokinin 1 receptor in the
rodent brainstem in the modulation of nociception after injury.
 Responsible for the design and conduct of the experiments, graphic
presentation and statistical analysis of the data, preparation of manuscripts
and data presentation in lab meetings and international meetings
 Responsible for supervision of undergraduate and graduate students
 Techniques:
o Small animal surgery including stereotaxic placement of cannulae in the
brain and injection of tracers in the spinal cord.
o Measurement of pain behaviors in the conscious laboratory rodent
o Von Frey test filaments to measure mechanical nociception
o Hargreaves test for thermal nociception
o Assessment of spontaneous and evoked pain behaviors after
capsaicin injection.
 Brain, dorsal root ganglia and spinal cord tissue dissections from rat.
 RNA isolation, RT-PCR and qPCR
 Light and confocal microscopy
 Single, double and triple-label immunohistochemical methods
 Retrograde, as well as anterograde tracing methods
 Quantitative analysis of immunohistochemical data using Autoneuron and
StereoInvestigator image analysis software.
HONORS
PhD Fellowship from the “Agencia Nacional de Promoción Científica y Tecnológica”
(National Agency for the Advancement of Science and Technology).
Awarded through a national competition.
April 2005 – December 2007
PhD Fellowship from the “Secretary of Science and Technology of the University of
Córdoba” (SECYT), February 2004 to March 2005. Advisor: Héctor López PhD.
TEACHING EXPERIENCE
University of Iowa
Spring 2015 “Mechanisms of Pain Transmission” Coordinator
Fall/Spring 2014 “Neurochemistry and Neuropharmacology Series”
1 hr lecture Norepinephrine & Epinephrine
1 hr lecture Dopamine
1 hr lecture Serotonin & Histamine
1 hr lecture Neuropeptides

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Spring 2013 101:902:001 Molecular and Neural Mechanisms of Pain
1 hr lecture: Animals Models of Pain
Fall 2011 101:277 Mechanisms of Pain Transmission
1 hr lecture: Methods for Assessment of Acute Pain
Universidad Nacional de Córdoba- Argentina
2007 Coordinator and Teaching Tutor of the graduate course
“Psychophysiology of Pain”. Psychology Program, School of
Psychology
2005/2006 Teaching Tutor (Docente Tutor) in the undergraduate course
“Psychophysiology of Pain”. Psychology Program, School of
Psychology
2004/2005 Assistant (Adscripto) in “Neurophysiology and Psychophysiology”
School of Psychology
2000/2001 Teaching Tutor (Docente tutor) the undergraduate course “Initiation
Course on Psychology”. Psychology Program, School of Psychology
1999-2001 Teaching Assistant of Neurophysiology and Psychophysiology
School of Psychology
1999-2000 Teaching Assistant of Social Psychology
School of Psychology
MENTORING EXPERIENCE
2008 - 2016 First-line supervisor for graduate student; responsible for training and
oversight of experiments
Trained and supervised graduate student in conduct of
immunohistochemistry techniques and quantification.
2005 – 2008 Trained multiple individuals in small animal surgery and handling
skills
Trained and supervised undergraduate student in conduct of pain
behavioral tests.
2006/2007 Co-Director of the research work of Federico Scabuzzo, recipient of a
fellowship from the Córdoba Agency of Science (Cordoba, Argentina)
Title: Skeletal muscle pain: behavioral effects of intramuscular
application of carrageenan in the rat during development
INVITED SEMINARS
2015 BCRG Breast Cancer Tumor Board, University of Iowa “Chemotherapy-
Induced Peripheral Neuropathy (CIPN): When Cancer Treatment Packs a Painful
Punch”

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2014 University of Iowa Neurology Grand Rounds “NK1 receptor upregulation in the
Rostral Ventromedial Medulla: One of the ways that Substance P participates in the
maintenance of peripheral inflammatory pain”
PUBLICATIONS
Refereed Journals
1) Hamity MV, White SR, Hammond DL. Effects of neurokinin-1 receptor agonism
and antagonism in the rostral ventromedial medulla of rats with acute or
persistent inflammatory nociception. Neuroscience 2010; 165:902-13.
2) Hamity MV, Walder RY and Hammond DL. Increased neuronal expression of
Neurokinin-1 receptor and stimulus-evoked internalization of the receptor in the
rostral ventromedial medulla of the rat after peripheral inflammatory injury.
Journal of Comparative Neurology 2014; 522:3037-3051
3) Walder RY, Wattiez AS, White SR, Marquez de Prado B, Hamity MV and
Hammond DL. Validation of four reference genes for quantitative mRNA
expression studies in a rat model of inflammatory injury. Molecular Pain 2014;
10(1):55.
4) Maduka UP, Hamity MV, Walder RY, White SR., Li Y and Hammond DL.
Changes in the disposition of Substance P in the Rostral Ventromedial Medulla
after Inflammatory Injury in the Rat. Neuroscience 2016; 317:1-11.
5) Hamity MV, White SR, Schmidt M, Walder RY, Brenner C and Hammond DL.
Nicotinamide riboside, an NAD+ precursor and nutritional supplement, relieves
the nociceptive and aversive dimensions of paclitaxel-induced peripheral
neuropathy in female rats. Under revision
6) Hamity MV, Maduka UP and Hammond, DL. Release of substance P (Sub P) in
the rat rostral ventromedial medulla (RVM): Modulation by inflammatory injury
and presynaptic N-methyl-D-aspartate receptors (NMDARs) In preparation
CONFERENCES and PRESENTATIONS (out of 25 communications)
1) Hamity M., White S.R., Schmidt M, Walder R. Y., Brenner C. and Hammond
D. “Nicotinamide riboside: a novel approach to treating peripheral neuropathy
induced by paclitaxel in female rats”. Program No 145.01/Z6San Diego, CA:
Society for Neuroscience, 2016. Online.
2) Nicotinamide riboside, a novel approach to treat peripheral neuropathy
induced by paclitaxel. 2016 Holden Comprehensive Cancer Center (HCCC)
Scientific Retreat. Coralville, Iowa.
3) Hamity M., White S.R., Schmidt M, Walder R. Y., Brenner C. and Hammond
D. “Nicotinamide riboside, a novel approach to treat peripheral neuropathy
induced by paclitaxel”. Health Sciences Research Week. University of Iowa,
Iowa. 2016

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4) Hamity M., Maduka U., Hammond D.” Dissecting the mechanism of substance
P release in the rat rostral ventromedial medulla during inflammatory injury)”
Program no 151.17/M20 Neuroscience Meeting Planner. Chicago, IL: Society
for Neuroscience, 2015. Online.
5) Hamity M., Maduka U., Walter K., Hammond D. ”Release of substance P
(SP) in the rat rostral ventromedial medulla (RVM): Modulation by
inflammatory injury and presynaptic N-methyl-D-aspartate receptors
(NMDARs)” Program no 461.01/XX12 Neuroscience Meeting Planner.
Washington DC: Society for Neuroscience, 2013. Online.
6) Hamity M., Hammond D. “Peripheral inflammation increases the number of
neurokinin-1 receptor (NK1-R) expressing neurons in the rostral ventromedial
medulla (RVM)”. Program no 805.05/NN312011 Neuroscience Meeting
Planner. Washington DC: Society for Neuroscience, 2011. Online.
7) Maduka U., Hamity M., Hammond D. “Unilateral inflammatory injury does not
increase levels of Substance P (SP) in the rostral ventromedial medulla
(RVM), dorsal root ganglia (DRG) or dorsal horn of the rat. Program no
805.05/NN32 Neuroscience Meeting Planner. Washington DC: Society for
Neuroscience, 2011. Online.
8) NK1 receptor upregulation in the RVM: One of the ways that Substance P
participates in the maintenance of peripheral inflammatory pain. Midwest Pain
Interest Group Meeting. (Chicago, IL) July, 2011.
9) Effects of Neurokinin-1 receptor agon ism and antagonism in the RVM under
pain conditions. Midwest Pain Interest Group Meeting. (Indianapolis, IN)
June, 2010.
10)Hamity M, Takenami T, Engle M, Domeyer A and Hammond D. “ Spinal
Nerve Ligation Causes A Selective Upregulation of Alpha2Delta
Immunoreactivity on Small Diameter Dorsal Root Ganglion Neurons “.The
Journal of Pain , Volume 10 , Issue 4 , S30
11)Hamity, Marta; White, Stephanie: Hammond, D “Reversal of Thermal
Hyperalgesia by Microinjection of Neurokinin-1 Receptor (NK1) Antagonist in
the Rostral Ventromedial Medulla (RVM)” Program no 72.7/LL11
Neuroscience Meeting Planner. Washington DC: Society for Neuroscience,
2008. Online.
12)Hamity, Marta; López, H. “Characterization of a subpopulation of sensory
neurons in the DRG and their function in muscle pain”. VII Congress of Pain,
Gramado, Porto Alegre. Brazil. August, 2006.
13)Hamity, Marta; López H. “Analysis of the pain behavioral response of rats
subjected to natural algesic stimuli into skeletal muscle at different ages
during early ontogeny” .11th World Congress on Pain®. Sydney, Australia.
August, 2005.
14)Hamity, Marta; López, H. “Analysis of the muscle pain response in rats treated
with capsaicin”. Congress of Biomedical Societies. Mar del Plata, Argentina.
November 2004.

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PROFESIONAL MEMBERSHIPS
 Member of Society of Neuroscience from 2008/present
MANUSCRIPT REVIEWER
Brain Research 2016
Neuropharmacology 2012
Journal of Pain 2011
Neuroscience 2010
Journal of Pharmacology and Experimental Therapeutics 2010