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SPECIALIZED ROLE : ONCOLOGY NURSE
Manjunathan C.,
RN RPN., M.Sc.(N)., M.Sc.,(CP)., PhD.,(ON),
AGM-Nursing I Operations I JCI Coordinator,
Apollo CBCC Cancer Care,
Apollo Hospitals International Ltd.
Goals of Cancer Treatment,
Expected Complications:
“Hands of Specialized Nurses Role”
• What am I going to Learn Today????
1. Definition
2. Goals of Cancer treatment
3. Complications –
* Chemotherapy
* Radiation Therapy
* Surgical therapy
* Bone marrow Transplantation/Stem Cell Transplantation
4. Role of specialized Nurse
Define: Cancer
Cancer:
A disease caused by an uncontrolled division of abnormal cells in a part
of the body.
Chemotherapy Radiation therapy Surgical therapy
Adjuvant therapy Neoadjuvant therapy
Types of Cancer Therapy
Goals of Cancer Treatment
To cure the
cancer
To control the
cancer
To ease cancer
symptoms
(sometimes -
palliation)
Complications
Chemo-
Therapy
Radiation-
Therapy
Bone Marrow
Transplantation
Surgical-
Therapy
A Glimpse-Chemotherapy
Chemotherapy Interfering with tumor cells -ability to grow and
proliferate
Adjuvant chemotherapy - localized breast cancer
Neo-adjuvant chemotherapy
Induction chemotherapy
Maintenance chemotherapy AML
Consolidated chemotherapy
Targeted Therapy-Hormonal Therapy
Salvage chemotherapy
Intense chemotherapy (High dose-Chemotherapy)-BMT
Curative chemotherapy - Diffuse Large B Cell Lymphoma
Palliative chemotherapy
Categories
•Antibiotic Derived - Anthracyclines, Bleomycin
•Plant Alkaloids (Periwinkle Plant) -Vincristine, Paclitaxel
•Alkylators - Cylcophosphamide
•Antimetabolites (interfere With Synthesis Of Nucleic Acids)-5fu, Methotrexate
•Epipodophyllotoxins (inhibit Topoisomerase 2) - Etoposide
•Anti-hormonal - Tamoxifen, Coritcosteroids
•Tyrosine Kinase Inhibitors - Imantinib
•Monoclonal Antibodies (targeted Therapy) - Rituximab
Chemotherapy
Chemotherapy
Nausea & Vomiting
Fatigue
Infection
Mouth & Sore Throat
Alopecia(Hair loss)
Weight Gain or Weight loss
Nail Weakness
Hemorrhagic Cystitis
Memory Problems(Chemo- Brain)
Extravasation
Cont…
Chemotherapy
Chemotherapy-Induced Peripheral
Neuropathy
Bone marrow suppression
Early Menopause
Diarrhoea
Infertility
Skin Changes
VMAT /
RapidArc
IMRT
IGRT
SRS
SBRT
Techniques-Radiotherapy
Teletherapy
Brachytherapy
LDR (Low Dose
Rate) Brachytherapy
HDR (High Dose
Rate) Brachytherapy
Cont…,
xerostomia Radiation
fibrosis
Desqumation
(Dry/Moist)
Hypothalamic
Dysfunction
Oesophagea
l Toxicity
(Strictures)
Dysphagia Thyroid
Dysfunction
Ototoxicity
Nervous
system
Dysfunction
Arterial
Injury
Contractures Myelitis
Trismus Burns Ocular toxicity Proctitis
Infection
Pain
Drain
Care/Fistula
Mobilization
Lymphede
ma
Body
Image
Appetite
loss
Bleeding
Fatique,
Sexuality/
Reproduct
ion
Post Surgical Onco Nursing Care
Types of Bone Marrow/Stem Cell Collection
Apharesis
Umbilical cord
Bone
Marrow
Peripheral
Types of Stem Cell transplantation
Allogeneic
*Haplo-Indentical/Half
Matched
*Syngenic-Identical
*MUD
*Mini transplants
Autologus
Acute Toxicities
Busulfan
seizures, pulmonary fibrosis
Calci-neurin inhibitors
seizures, renal failure
Cyclophosphamide
cardiomyopathy, neuropathy, SIADH
Toxicities may happen in all the phases of Bone Marrow Transplantation
Toxicitites in conditioning Phase are:
Drug & Metabolic Disturbances
Cont…,
Ifosfamide
Encephalopathy
Melphalan
mucositis, cardiomyopathy, pulmonary fibrosis
Total body irradiation
parotitis, mucositis, cardiomyopathy, pericarditis
Dimethylsulfoxide
desaturation, hemolysis, seizures, dysgeusia, cholinergic
responses
Cont…Post Induction/Conditioning Phase
• Infection
Neutropenia
• Infection
Neutropenia
• Infection
Neutropenia
Role of Nurse
Isolation
Periodic assessment and Investigations
Care of lines, tubes and drains
Mouth Care, Nostrils, axilla & Groin care
Neutropenic Diet
Sterlization of articles
& Room Cleaning
Medication
Management
Immunocompromized
/ Neutropenia-Special
Care
Role of bedside RN- Isolation
• Positive pressure
• HEPA filter
• PPEs
• Visitor Restriction
• Aseptic Precautions
Cont...
• Hand Hygiene: Hand wash before and after using toilet.
• Hand washing to be done while entering the unit
• Advice Health professional to wear mask and to avoid encoutering
patients when they have a cold or URI
• Advice patient to wear mask when they walk in the corridor
• Protect client from others with infections and those who have recently
been vaccinated (a person may have a subclinical infection after a
vaccination)
Role of bedside RN- Periodic Assessment and
Investigation
• Hemodynamic stabilization
• Investigation:
– Complete Blood Count (with Differential)
-White cells, haemoglobin, platelets
– Biochemistry
-Electrolytes, urea, creatinine, Liver function
– Microbiology
-Blood cultures (peripheral and all central line lumens)
-Oral ulcers or sores –send swabs ( Viral Cx and fungal Cx )
-Exit site swabs
-Wound swabs
-Urine Cultures
-Stool Cultures
– Radiology
-Chest Xray
Role of bedside RN- Care of Lines & Tubes
 Central line dressing once in two/three days
 Frequent flushing of line
 Minimal use of lines
 Avoid invasive procedures (e.g. urinary catheterizations, arterial and
venous punctures, injections) whenever possible; if such procedures are
necessary, perform them using sterile technique
 Change intravenous insertion sites/tubings according to hospital policy
• Anchor catheters/tubings (e.g. urinary, intravenous) securely in order to
reduce trauma to the tissues and the risk for introduction of pathogens
associated with the in-and-out movement of the tubing
• Maintain a closed system for drains (e.g. urinary catheter) and
intravenous infusions whenever possible
Role of bedside RN- Care of Mouth,
Nostrils, Axilla and Groins
 Rinse mouth with chlorhexidine/ cephasole solution thrice a day
 Sitz bath twice a day
 Neosporin powder in the groin and axilla
 Candid mouth paint for the tongue
 Fusidin ointment for nostrils
 Zinc oxide to prevent excoriation
 Avoid Clipping Nails
 Preventing constipation: Initiate measures to prevent constipation &
prevent damage to the bowel mucosa from hard stool
 Avoid unnecessary rectal invasion (e.g. temperature taking, enemas,
suppositories, rectal tube) to prevent trauma to rectal mucosa and
possible abscess formation
Role of bedside RN
- Medication Management
• Antibacterial, antiviral and antifungal systemically
• < 7 days of neutropenia
~ response rates to initial antimicrobial therapy was 95%, compared to
only 32% in patients with more than 14 days of
Immunocompromized / neutropenia ( <.001)
~ patients with intermediate durations of neutropenia between 7 and 14
days had response rates of 79%
1988,Rubin and colleagues
Role of bedside RN- Immunocompromized
/ Neutropenic Diet
• Avoid raw and undercooked meat
• Double boiled Foods
• Preservatives should not be used: Tinned foods, cheese etc
• Outdated products should not be consumed.
• In patients with periodontitis and stomatitis, a soft or full liquid diet is
indicated.
• Maintain a fluid intake of at least 2500 ml/day unless contraindicated
• Avoid spicy and acidic foods
• Eat only fruits and vegetables that can be washed or cooked.
• Eat only meat that is fully cooked.
• Avoid drinking unpasteurized milk or other unpasteurized beverages.
Role of bedside RN- Sterlization & Cleaning
• Autoclave
– RN Scrub
– Patient gowns
– Pillow cover
– Bed spread
– Linens
• Regular room cleaning : Advice cleaning of the room when patient is not
in the room
• Deep Cleaning when required
• Before using equipments (stethoscope, infusion pumps, etc.) from this
room for other patients clean them thoroughly with 70% Alcohol.
• Advice not to use sharp play material and have all items sterilized
Role of IC Nurse
• Daily surveillance
• Coordination with HIC committee members and other Medical team
Operations team-
• Auditing practices
Deep cleaning
Nursing practices
• Maintaining schedule of Air vent cleaning, HEPA filter validation /
change
• Coordination with Biomedical Engineers on Room Pressure
• Educating Bedside nurses on Reverse barrier techniques
• Conducting link nurses meeting with supervisors and other important
• Tracking Quality Indicators
Best Infection Control Practices-Mandate
for Oncology
Ventilation
Construction
Isolation
Hand
Hygiene
EquipmentPlants
Play
Areas &
Toys
Health
Care
Workers
Visitors
Cont...
Patient Skin
Care
Oral & Dental
Care
Prevention of
Bacterial Infection
Related to
Intravascular
Catheter
Drug-Resistant
Organisms
Specific
Nosocomical
Infections
Legionellosis
Community
Respiratory
Virus Infection
Mycobacteriu
m
Tuberculosis
Infection
Control
Surveillance
Ref: Clare A. Dykewicz-Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Cont..,
Toxicities result from profound from during Recovery Phase are;
Marrow suppression
Infectious
Hematologic
Thrombotic microangiopathies
–Hemolytic uremic syndrome
–Risks: female graft, older recipient, viral/fungal infections,
calcineurin inhibitors
Lung injuries
–carmustine, cyclophosphamide, busulfan, melphalan, total
body irradiation
Cont..,
Cytokine storm
- Increased risk with rapid engrftment
–capillary leak, oxygen desaturation,
–Differences with GM-CSF vs G-CSF?
Sinusoidal occlusive syndrome (SOS, veno-occlusive
disease [VOD])
–Risks: cyclophosphamide or busulfan; prior
gemtuzumab ozogamicin; allogeneic SCT
Acute graft versus host
–skin rash, diarrhea, elevated transaminases
Certainly My role is Important
• Rehab-Care• Survivor
Care
• Supportive
Care
• Symptom
Management
Patient
Assessment
Patient
Education
Coordinati
on of Care
Direct
Patient
Care
Major Role-Onco Nurse
Leadership
within the MDT
& wider cancer
team
Innovation, project
management and
change
management
In-depth
knowledge of a
tumor area
Excellent decision
making abilities
Empathy for
patients & their
families
Advanced
communication &
advocacy skills
Ability to assess
patients’ holistic
needs
Acting as a key
worker across
the whole care
pathway
Advanced/
clinical
diagnostic skills
No More Slow….
When you become more
slow to accept, adapt and
adopt an advanced
Technologies in the
system
Then we will be????
-
Take home message!!!
Don’t wish it were easier, wish
You were Better,
Don’t wish for fewer problems
Wish for more Skills
Don’t wish for less challenges,
Wish for more Wisdom
- Carl Shoaf
“We have two jobs: Our job and
the job of improving our job”.
THANK YOU
AnyFurtherqueriesreachme @:
manjunathan1801@gmail.com

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Specialized Role:Oncology Nurse

  • 1. SPECIALIZED ROLE : ONCOLOGY NURSE Manjunathan C., RN RPN., M.Sc.(N)., M.Sc.,(CP)., PhD.,(ON), AGM-Nursing I Operations I JCI Coordinator, Apollo CBCC Cancer Care, Apollo Hospitals International Ltd. Goals of Cancer Treatment, Expected Complications: “Hands of Specialized Nurses Role”
  • 2. • What am I going to Learn Today???? 1. Definition 2. Goals of Cancer treatment 3. Complications – * Chemotherapy * Radiation Therapy * Surgical therapy * Bone marrow Transplantation/Stem Cell Transplantation 4. Role of specialized Nurse
  • 3. Define: Cancer Cancer: A disease caused by an uncontrolled division of abnormal cells in a part of the body.
  • 4. Chemotherapy Radiation therapy Surgical therapy Adjuvant therapy Neoadjuvant therapy Types of Cancer Therapy
  • 5. Goals of Cancer Treatment To cure the cancer To control the cancer To ease cancer symptoms (sometimes - palliation)
  • 7.
  • 8. A Glimpse-Chemotherapy Chemotherapy Interfering with tumor cells -ability to grow and proliferate Adjuvant chemotherapy - localized breast cancer Neo-adjuvant chemotherapy Induction chemotherapy Maintenance chemotherapy AML Consolidated chemotherapy Targeted Therapy-Hormonal Therapy Salvage chemotherapy Intense chemotherapy (High dose-Chemotherapy)-BMT Curative chemotherapy - Diffuse Large B Cell Lymphoma Palliative chemotherapy
  • 9. Categories •Antibiotic Derived - Anthracyclines, Bleomycin •Plant Alkaloids (Periwinkle Plant) -Vincristine, Paclitaxel •Alkylators - Cylcophosphamide •Antimetabolites (interfere With Synthesis Of Nucleic Acids)-5fu, Methotrexate •Epipodophyllotoxins (inhibit Topoisomerase 2) - Etoposide •Anti-hormonal - Tamoxifen, Coritcosteroids •Tyrosine Kinase Inhibitors - Imantinib •Monoclonal Antibodies (targeted Therapy) - Rituximab
  • 10. Chemotherapy Chemotherapy Nausea & Vomiting Fatigue Infection Mouth & Sore Throat Alopecia(Hair loss) Weight Gain or Weight loss Nail Weakness Hemorrhagic Cystitis Memory Problems(Chemo- Brain) Extravasation
  • 11. Cont… Chemotherapy Chemotherapy-Induced Peripheral Neuropathy Bone marrow suppression Early Menopause Diarrhoea Infertility Skin Changes
  • 12.
  • 14. Cont…, xerostomia Radiation fibrosis Desqumation (Dry/Moist) Hypothalamic Dysfunction Oesophagea l Toxicity (Strictures) Dysphagia Thyroid Dysfunction Ototoxicity Nervous system Dysfunction Arterial Injury Contractures Myelitis Trismus Burns Ocular toxicity Proctitis
  • 15.
  • 17.
  • 18. Types of Bone Marrow/Stem Cell Collection Apharesis Umbilical cord Bone Marrow Peripheral
  • 19. Types of Stem Cell transplantation Allogeneic *Haplo-Indentical/Half Matched *Syngenic-Identical *MUD *Mini transplants Autologus
  • 20. Acute Toxicities Busulfan seizures, pulmonary fibrosis Calci-neurin inhibitors seizures, renal failure Cyclophosphamide cardiomyopathy, neuropathy, SIADH Toxicities may happen in all the phases of Bone Marrow Transplantation Toxicitites in conditioning Phase are: Drug & Metabolic Disturbances
  • 21. Cont…, Ifosfamide Encephalopathy Melphalan mucositis, cardiomyopathy, pulmonary fibrosis Total body irradiation parotitis, mucositis, cardiomyopathy, pericarditis Dimethylsulfoxide desaturation, hemolysis, seizures, dysgeusia, cholinergic responses
  • 22. Cont…Post Induction/Conditioning Phase • Infection Neutropenia • Infection Neutropenia • Infection Neutropenia
  • 23. Role of Nurse Isolation Periodic assessment and Investigations Care of lines, tubes and drains Mouth Care, Nostrils, axilla & Groin care Neutropenic Diet Sterlization of articles & Room Cleaning Medication Management Immunocompromized / Neutropenia-Special Care
  • 24. Role of bedside RN- Isolation • Positive pressure • HEPA filter • PPEs • Visitor Restriction • Aseptic Precautions
  • 25. Cont... • Hand Hygiene: Hand wash before and after using toilet. • Hand washing to be done while entering the unit • Advice Health professional to wear mask and to avoid encoutering patients when they have a cold or URI • Advice patient to wear mask when they walk in the corridor • Protect client from others with infections and those who have recently been vaccinated (a person may have a subclinical infection after a vaccination)
  • 26. Role of bedside RN- Periodic Assessment and Investigation • Hemodynamic stabilization • Investigation: – Complete Blood Count (with Differential) -White cells, haemoglobin, platelets – Biochemistry -Electrolytes, urea, creatinine, Liver function – Microbiology -Blood cultures (peripheral and all central line lumens) -Oral ulcers or sores –send swabs ( Viral Cx and fungal Cx ) -Exit site swabs -Wound swabs -Urine Cultures -Stool Cultures – Radiology -Chest Xray
  • 27. Role of bedside RN- Care of Lines & Tubes  Central line dressing once in two/three days  Frequent flushing of line  Minimal use of lines  Avoid invasive procedures (e.g. urinary catheterizations, arterial and venous punctures, injections) whenever possible; if such procedures are necessary, perform them using sterile technique  Change intravenous insertion sites/tubings according to hospital policy • Anchor catheters/tubings (e.g. urinary, intravenous) securely in order to reduce trauma to the tissues and the risk for introduction of pathogens associated with the in-and-out movement of the tubing • Maintain a closed system for drains (e.g. urinary catheter) and intravenous infusions whenever possible
  • 28. Role of bedside RN- Care of Mouth, Nostrils, Axilla and Groins  Rinse mouth with chlorhexidine/ cephasole solution thrice a day  Sitz bath twice a day  Neosporin powder in the groin and axilla  Candid mouth paint for the tongue  Fusidin ointment for nostrils  Zinc oxide to prevent excoriation  Avoid Clipping Nails  Preventing constipation: Initiate measures to prevent constipation & prevent damage to the bowel mucosa from hard stool  Avoid unnecessary rectal invasion (e.g. temperature taking, enemas, suppositories, rectal tube) to prevent trauma to rectal mucosa and possible abscess formation
  • 29. Role of bedside RN - Medication Management • Antibacterial, antiviral and antifungal systemically • < 7 days of neutropenia ~ response rates to initial antimicrobial therapy was 95%, compared to only 32% in patients with more than 14 days of Immunocompromized / neutropenia ( <.001) ~ patients with intermediate durations of neutropenia between 7 and 14 days had response rates of 79% 1988,Rubin and colleagues
  • 30. Role of bedside RN- Immunocompromized / Neutropenic Diet • Avoid raw and undercooked meat • Double boiled Foods • Preservatives should not be used: Tinned foods, cheese etc • Outdated products should not be consumed. • In patients with periodontitis and stomatitis, a soft or full liquid diet is indicated. • Maintain a fluid intake of at least 2500 ml/day unless contraindicated • Avoid spicy and acidic foods • Eat only fruits and vegetables that can be washed or cooked. • Eat only meat that is fully cooked. • Avoid drinking unpasteurized milk or other unpasteurized beverages.
  • 31. Role of bedside RN- Sterlization & Cleaning • Autoclave – RN Scrub – Patient gowns – Pillow cover – Bed spread – Linens • Regular room cleaning : Advice cleaning of the room when patient is not in the room • Deep Cleaning when required • Before using equipments (stethoscope, infusion pumps, etc.) from this room for other patients clean them thoroughly with 70% Alcohol. • Advice not to use sharp play material and have all items sterilized
  • 32. Role of IC Nurse • Daily surveillance • Coordination with HIC committee members and other Medical team Operations team- • Auditing practices Deep cleaning Nursing practices • Maintaining schedule of Air vent cleaning, HEPA filter validation / change • Coordination with Biomedical Engineers on Room Pressure • Educating Bedside nurses on Reverse barrier techniques • Conducting link nurses meeting with supervisors and other important • Tracking Quality Indicators
  • 33. Best Infection Control Practices-Mandate for Oncology Ventilation Construction Isolation Hand Hygiene EquipmentPlants Play Areas & Toys Health Care Workers Visitors
  • 34. Cont... Patient Skin Care Oral & Dental Care Prevention of Bacterial Infection Related to Intravascular Catheter Drug-Resistant Organisms Specific Nosocomical Infections Legionellosis Community Respiratory Virus Infection Mycobacteriu m Tuberculosis Infection Control Surveillance Ref: Clare A. Dykewicz-Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • 35. Cont.., Toxicities result from profound from during Recovery Phase are; Marrow suppression Infectious Hematologic Thrombotic microangiopathies –Hemolytic uremic syndrome –Risks: female graft, older recipient, viral/fungal infections, calcineurin inhibitors Lung injuries –carmustine, cyclophosphamide, busulfan, melphalan, total body irradiation
  • 36. Cont.., Cytokine storm - Increased risk with rapid engrftment –capillary leak, oxygen desaturation, –Differences with GM-CSF vs G-CSF? Sinusoidal occlusive syndrome (SOS, veno-occlusive disease [VOD]) –Risks: cyclophosphamide or busulfan; prior gemtuzumab ozogamicin; allogeneic SCT Acute graft versus host –skin rash, diarrhea, elevated transaminases
  • 37. Certainly My role is Important • Rehab-Care• Survivor Care • Supportive Care • Symptom Management Patient Assessment Patient Education Coordinati on of Care Direct Patient Care
  • 38. Major Role-Onco Nurse Leadership within the MDT & wider cancer team Innovation, project management and change management In-depth knowledge of a tumor area Excellent decision making abilities Empathy for patients & their families Advanced communication & advocacy skills Ability to assess patients’ holistic needs Acting as a key worker across the whole care pathway Advanced/ clinical diagnostic skills
  • 39. No More Slow…. When you become more slow to accept, adapt and adopt an advanced Technologies in the system Then we will be????
  • 40.
  • 41. - Take home message!!! Don’t wish it were easier, wish You were Better, Don’t wish for fewer problems Wish for more Skills Don’t wish for less challenges, Wish for more Wisdom - Carl Shoaf
  • 42. “We have two jobs: Our job and the job of improving our job”. THANK YOU AnyFurtherqueriesreachme @: manjunathan1801@gmail.com