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The role of
Nuclear Medicine
in treatment of Cancer
Layal K.Jambi
Tutor: Bernardine Briggs
EUS3, University of Surrey
June 2012
Outline
• Biological and pathological features of
cancer.
• Methods of treatment.
• Nuclear Medicine and some
applications.
What is Cancer ?
• Cancer is the abnormal, uncontrolled
growth of normal cells.
• The abnormal change of a cell is due to
alteration to its DNA.
Tumors types
Warning signs of cancer
Methods of Prevention
Early detection of cancer
• Importance
– Give the best chance of cure.
– Cost-effective mean of control.
Treatment
Treatment
11
22
33
44
55
NuclearNuclear
MedicineMedicine
• Sometimes seeing
things from the
Outside doesn't tell
the whole story.
• It may looks okay, but
on the Inside it may
NOT be okay.
• Nuclear Medicine is an area of Radiology
that Allows doctors to see from the
Outside how the body is working Inside
What is Nuclear Medicine ?
• Nuclear Medicine is a medical specialty
that is used to Diagnose and Treat
diseases in a safe and painless way.
Why it is called Nuclear Medicine ?
• Nuclear Medicine refers to ( a Pharmaceutical )
that is attached to a small quantity of
Radioactive Material ( a Radioisotope )
Therapeutic Application of NM
11
22
33
44
I-131 Therapy
• Thyroid Cancer and Graves Disease.
• I-131 Capsules.
• Thyroid tenderness, salivary gland
swelling and nausea.
Zevalin
• Non-Hodgkin’s lymphoma
• IV infusion.
• Mild to moderate flu-like symptoms.
TheraSphere
• Hepatocellular carcinoma.
• Injection of TheraSphere.
• Fatigue, nausea, fever, vomiting and
stomach pain.
Samarium Therapy
• Relieve bone pain.
• Injection of radiopharmaceutical.
• Myelosuppression and an increase
pain in the sites being treated
To sum up
• NM is now producing numerous therapeutic
techniques that can replace other modalities due
to it being considered safe, painless and a cost-
effective technique.
References
•Almeida, C. (2010). Cancer: Basic Science and Clinical Aspects.
Chichester: Wiley Blackwell.
•Brenner, W & Eary, J. (2007). Nuclear Medicine Therapy. New York:
Informa Healthcare.
•IAEA. (2006). Nuclear Medicine Resources Manual. Austria: IAEA.
•Souhami, R. (2005). Cancer and its Management. 5th
Ed. Oxford:
Blackwell.

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