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Objectives of Preformulation: Characterizing Drug Properties

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KashviDesai

preformulation studies

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OBJECTIVES OF PREFORMULATION By: KASHVI DESAI KRUPA BAROT
• Preformulation is the stage of development during which the physicochemical properties of the drug substance are characterized and established. • Objective of preformulation • study is to develop the elegant, stable, effective and safe dosage form by establishing kinetic rate profile, compatibility with the other ingredients and establish Physico-chemical parameter of new drug substances. • Physicochemical properties of drug: The ability of a chemical compound to elicit a pharmacological/ therapeutic effect is related to the influence of various physical and chemical (physicochemical) properties of the chemical substance on the bio molecule that it interacts with.
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Objectives of Preformulation: Characterizing Drug Properties

  • 2. • Preformulation is the stage of development during which the physicochemical properties of the drug substance are characterized and established. • Objective of preformulation • study is to develop the elegant, stable, effective and safe dosage form by establishing kinetic rate profile, compatibility with the other ingredients and establish Physico-chemical parameter of new drug substances. • Physicochemical properties of drug: The ability of a chemical compound to elicit a pharmacological/ therapeutic effect is related to the influence of various physical and chemical (physicochemical) properties of the chemical substance on the bio molecule that it interacts with.
  • 3.
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  • 6.