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GOPIKA RANJITH
 PHYSICS
the emission of energy as electromagnetic
waves or as moving subatomic
particles,especially high-energy particles that
cause ionization
 BIOLOGY
divergence out from a central point,in
particular evolution from an ancestral animal or
plant group into a variety of new forms
 Ionizing Radiation
 Ultraviolet radiation
 X-ray
 Gamma radiation
 Alpha radiation
 Beta radiation
 Neutron radiation
 Non-Ionizing
Radiation
 Ultraviolet light
 Visible light
 Infrared
 Microwave
 Radio waves
 Thermal
radiation(heat)
 Black body radiation
 Dose
- Exposure and Exposure rate
- Absorbed dose
- Dose equivalent
 The amount of ionizing radiation a person is
exposed to
 Expressed as roentgens(R)
 Can be directly measured and is expressed as
R/min or milli R/hour
 The amount of energy deposited in tissue(the
amount of radiation needed to transfer a
certain amount of energy ie,1J/Kg)
 Expressed as gray(Gy) or rad (1Gy=100rad)
 Absorbed dose varies with type of tissue
ie,bone=5.0,soft tissue=0.95
 The absorbed dose multiplied a quality factor
allowing for different tissue sensitivities
 Expressed as Sievert(Sv) or rem (1Sv=100rem)
 Used to account for different biological
effects of radiation
 Rad,rem and roentgen have approximate
numerical equivalence in the x-ray energy
range used in the cardiac catheterization lab
 Production
Current is applied to a filament electrons are
released and accelerated towards a target by a
high voltage electrical potential
X-rays are produced when electrons collide
and are completely stopped by the
target(charecteristic x-rays)
Electrons are rapidly decelerated after striking
the target(breaking x-rays)
 Fluroscopy-type of x-ray examination used for
dynamic imaging
 Image intensifier-amplify the brightness of the
image to improve visibility
 X-ray transmitted through patient,enter the input
phophor which emits light that is then converted
to electrical energy
 The electrical energy is amplified and converted
back into light at the output phosphor
 Output phosphor of the image intensifier is
coupled to a television pickup tube which
converts the light pattern into an electrical signal
which forms the image on the monitor
 Light exiting the output phosphor is divided,
diverting part of the beam to television
monitor and the rest to the cine camera lens-
refocuses light onto cine film
 Standard cameras use 35 mm film at frame
rates of 15-60 frames/sec(15-30 fps for
angiography and 60 fps for ventriculography)
Limit of 10 R/minute
Patient radiation dependent on several factors
1.x-ray tube factors
2.Image intensifier factors
3.Distance factors
4.Patient factors
 Operator independent
kVp- voltage across the x-ray tube, the energy
that accelerates the electrons
intensity of x-ray and image brightness directly
related to the current passing through the filament
increasing the kVp produces higher energy
x-rays which have greater penetrating power for
large patients
optimal setting for adult70-80kVp
copper or aluminium filters placed between x-ray
tube and patient to absorb low energy x-rays that
are inadequate for imaging purposes
 Automatic brightness control-automatically
adjusted to maintain brightness
 Collimation
restrict the size of the x-ray field
 Field size and magnification
field size decreases with magnification,
therefore the local patient radiation dose must
increase to compensate for the loss of brightness
low magnification(9-11inch)
intermediate magnification(6-7inch)
high magnification(4-5inch)
 Skin exposure
1-2R/min in 9 inch mode
2-5R/min for smaller magnification modes
for 10 minutes of fluroscopy, patients skin
exposure is 10-50R(10-50rads)
 Skin radiation increases with decreasing
distance
 Table height affects patient dose
 Standard is to maintain 18” between x-ray
tube and patient
 Image intensifier should be as close to
patient as possible
 Prolonged or repeated cine runs
 Longer fluroscopy times
 Higher frame rates
All increase radiation exposure to the patient
 Age
 Health of patient
 Skin site
 Radiation Injury
Damage and repair
Somatic effects
Effects on developing embryo and fetus
 Injury produced by large amounts of energy
transferred to individual molecule
Cause ejection of electrons
Initiates physical and chemical effects on
tissues especially DNA
Failure of repair mechanism leads to cell
death or mutation
 Effects to tissue depend on:
> Amount of energy imparted
> Location and extent of region of body
exposed
> Time interval over which energy is
imparted
 Deterministic effects-those in which the
number of cells lost in an organ or tissue is
so great that there is a loss of tissue function
>IE skin erythema and ulceration
 Stochastic effects-occur if an irradiated cell is
modified rather than killed and then goes on
to reproduce
>Do not appear to have a threshold and
the probability of the effect occurring is
related to the radiation dose
* Observed early (days to week)
>Early effects develop in proliferating cell
systems (most radiosensitive skin,ocular lens,
testes,intestine,esophagus)
OR
*Observed late (months to year)
>Carcinogenesis is the most important delayed
somatic effect
>Delayed effects often seen in nerves,muscles
and other radioresistant tissues
 Five groups of patients known to have genetic
or chromosomal defects and an increased
sensitivity to various types of ionizing
radiation:
-Xeroderma pigmentosum
-Ataxia-telangiectasia
-Fanconi’s anemia
-Bloom syndrome
-Cockayne’s syndrome
 Determined by dose
-Bone marrow depression with whole body
radiation>500 rad
 Skin erythema occurs if a single dose of
6-8 Gy(600-800 rad) is given,and it is not
identified until 1-2 days after irradiation
 The higher the irradiation dose,the more
quickly the erythema may be identified
 Characterized by a blue or mauve
discoloration of the skin
 Increases during the first week
 Usually fades during the second week
 May return 2-3 weeks after the initial insult
and last for 20-30 days
 Acute doses in excess of 8Gy will produce
exudative and erosive changes in the skin
 Penetrating doses in excess of 20Gy: there is
usually a nonhealing ulceration
 May appear in a few hours or a few weeks
 The higher the dose,the shorter the period
for appearance
 Type 1 injury-damage limited to the
epidermis and dermis without much damage
to the subcutaneous tissue
-Initial erythema
-A 3wk latency period
-A secondary erythema followed by
-An exudative epidermatitis and recovery in
3-6 months
 Type II Injury
- A vascular endothelitis
- At least 6-8 months post exposure the acute
reactions are renewed with necrosis and
ulceration usually requiring surgery
- A result of damage below the basal layer of
the epidermis
 Necrosis within a few weeks of the acute
exposure
 Lab Specific
Constructed with 1.5mm of lead or
equivalent shielding to protect individuals in
the control room and adjacent areas
 Personal protection
- Time
- Distance
- Shielding
 Time
Radiation dose is proportional to exposure
duration
 Distance
Radiation dose is inversely proportional
to the square root of the distance from the
patient
 Shielding
- Lead is the most common material used
- A lead apron with an equivalent of 0.5mm of
lead in front panel is mandatory
- Lead in the back panel provides additional
protection
- Thyroid shield (0.5mm equivalence) is
recommended to shield the sternum,upper
breast and thyroid gland
 Shielding continued
- Leaded eyeglasses with the side shields
reduce the exposure to the eyes and may
improve visual acuity
- Recommended for staff with collar-badge
doses approaching 15rem per year and for
interventionalist’s training
 Shielding continued
- Hands receive the highest radiation dose,but
are relatively insensitive to radiation
- Supplemental lead shielding to reduce
exposure to scatter is available in the form of
table mounted lead drapes,ceiling mounted
lead acrylic shields and rolling lead acrylic
shields
 Interventionalists commonly assigned 2
radiation badges
- One on collar
- Second underneath lead apron
Lead apron reduces the radiation dose at the
waist to 10% of dose at collar at 75kVp
Effective dose equivalent best estimated by
averaging the 2 dosimeters
- Mean dose equivalent per procedure
4+/-2 millirem,highest doses were delivered
to physicians in training
 Women of child-bearing age should receive a
pregnancy test prior to procedure
 Current regulations restrict radiation dose to
the embryo and fetus to 500millirem for the
entire gestation and a monthly dose
<50millirem
 Pregnancy does not exclude working in the
cardiac catheterization lab
 Highest danger of fetal abnormalities is in the
first trimester
 Maturity lead aprons provide an additional
1mm of lead equivalence
 Use of properly fitting wrap-around apron
provides same protection to the fetus
 Fetal radiation badge should be worn on the
abdomen under the apron to record monthly
fetal exposure
RADIATION PHYSICS & SAFETY.pptx

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RADIATION PHYSICS & SAFETY.pptx

  • 2.  PHYSICS the emission of energy as electromagnetic waves or as moving subatomic particles,especially high-energy particles that cause ionization  BIOLOGY divergence out from a central point,in particular evolution from an ancestral animal or plant group into a variety of new forms
  • 3.  Ionizing Radiation  Ultraviolet radiation  X-ray  Gamma radiation  Alpha radiation  Beta radiation  Neutron radiation  Non-Ionizing Radiation  Ultraviolet light  Visible light  Infrared  Microwave  Radio waves  Thermal radiation(heat)  Black body radiation
  • 4.  Dose - Exposure and Exposure rate - Absorbed dose - Dose equivalent
  • 5.  The amount of ionizing radiation a person is exposed to  Expressed as roentgens(R)  Can be directly measured and is expressed as R/min or milli R/hour
  • 6.  The amount of energy deposited in tissue(the amount of radiation needed to transfer a certain amount of energy ie,1J/Kg)  Expressed as gray(Gy) or rad (1Gy=100rad)  Absorbed dose varies with type of tissue ie,bone=5.0,soft tissue=0.95
  • 7.  The absorbed dose multiplied a quality factor allowing for different tissue sensitivities  Expressed as Sievert(Sv) or rem (1Sv=100rem)  Used to account for different biological effects of radiation  Rad,rem and roentgen have approximate numerical equivalence in the x-ray energy range used in the cardiac catheterization lab
  • 8.  Production Current is applied to a filament electrons are released and accelerated towards a target by a high voltage electrical potential X-rays are produced when electrons collide and are completely stopped by the target(charecteristic x-rays) Electrons are rapidly decelerated after striking the target(breaking x-rays)
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  • 10.  Fluroscopy-type of x-ray examination used for dynamic imaging  Image intensifier-amplify the brightness of the image to improve visibility  X-ray transmitted through patient,enter the input phophor which emits light that is then converted to electrical energy  The electrical energy is amplified and converted back into light at the output phosphor  Output phosphor of the image intensifier is coupled to a television pickup tube which converts the light pattern into an electrical signal which forms the image on the monitor
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  • 13.  Light exiting the output phosphor is divided, diverting part of the beam to television monitor and the rest to the cine camera lens- refocuses light onto cine film  Standard cameras use 35 mm film at frame rates of 15-60 frames/sec(15-30 fps for angiography and 60 fps for ventriculography)
  • 14. Limit of 10 R/minute Patient radiation dependent on several factors 1.x-ray tube factors 2.Image intensifier factors 3.Distance factors 4.Patient factors
  • 15.  Operator independent kVp- voltage across the x-ray tube, the energy that accelerates the electrons intensity of x-ray and image brightness directly related to the current passing through the filament increasing the kVp produces higher energy x-rays which have greater penetrating power for large patients optimal setting for adult70-80kVp copper or aluminium filters placed between x-ray tube and patient to absorb low energy x-rays that are inadequate for imaging purposes
  • 16.  Automatic brightness control-automatically adjusted to maintain brightness  Collimation restrict the size of the x-ray field  Field size and magnification field size decreases with magnification, therefore the local patient radiation dose must increase to compensate for the loss of brightness low magnification(9-11inch) intermediate magnification(6-7inch) high magnification(4-5inch)
  • 17.  Skin exposure 1-2R/min in 9 inch mode 2-5R/min for smaller magnification modes for 10 minutes of fluroscopy, patients skin exposure is 10-50R(10-50rads)
  • 18.  Skin radiation increases with decreasing distance  Table height affects patient dose  Standard is to maintain 18” between x-ray tube and patient  Image intensifier should be as close to patient as possible
  • 19.  Prolonged or repeated cine runs  Longer fluroscopy times  Higher frame rates All increase radiation exposure to the patient
  • 20.  Age  Health of patient  Skin site
  • 21.  Radiation Injury Damage and repair Somatic effects Effects on developing embryo and fetus
  • 22.  Injury produced by large amounts of energy transferred to individual molecule Cause ejection of electrons Initiates physical and chemical effects on tissues especially DNA Failure of repair mechanism leads to cell death or mutation
  • 23.  Effects to tissue depend on: > Amount of energy imparted > Location and extent of region of body exposed > Time interval over which energy is imparted
  • 24.  Deterministic effects-those in which the number of cells lost in an organ or tissue is so great that there is a loss of tissue function >IE skin erythema and ulceration  Stochastic effects-occur if an irradiated cell is modified rather than killed and then goes on to reproduce >Do not appear to have a threshold and the probability of the effect occurring is related to the radiation dose
  • 25. * Observed early (days to week) >Early effects develop in proliferating cell systems (most radiosensitive skin,ocular lens, testes,intestine,esophagus) OR *Observed late (months to year) >Carcinogenesis is the most important delayed somatic effect >Delayed effects often seen in nerves,muscles and other radioresistant tissues
  • 26.  Five groups of patients known to have genetic or chromosomal defects and an increased sensitivity to various types of ionizing radiation: -Xeroderma pigmentosum -Ataxia-telangiectasia -Fanconi’s anemia -Bloom syndrome -Cockayne’s syndrome
  • 27.  Determined by dose -Bone marrow depression with whole body radiation>500 rad  Skin erythema occurs if a single dose of 6-8 Gy(600-800 rad) is given,and it is not identified until 1-2 days after irradiation  The higher the irradiation dose,the more quickly the erythema may be identified
  • 28.  Characterized by a blue or mauve discoloration of the skin  Increases during the first week  Usually fades during the second week  May return 2-3 weeks after the initial insult and last for 20-30 days  Acute doses in excess of 8Gy will produce exudative and erosive changes in the skin  Penetrating doses in excess of 20Gy: there is usually a nonhealing ulceration
  • 29.  May appear in a few hours or a few weeks  The higher the dose,the shorter the period for appearance
  • 30.  Type 1 injury-damage limited to the epidermis and dermis without much damage to the subcutaneous tissue -Initial erythema -A 3wk latency period -A secondary erythema followed by -An exudative epidermatitis and recovery in 3-6 months
  • 31.  Type II Injury - A vascular endothelitis - At least 6-8 months post exposure the acute reactions are renewed with necrosis and ulceration usually requiring surgery - A result of damage below the basal layer of the epidermis
  • 32.  Necrosis within a few weeks of the acute exposure
  • 33.  Lab Specific Constructed with 1.5mm of lead or equivalent shielding to protect individuals in the control room and adjacent areas
  • 34.  Personal protection - Time - Distance - Shielding
  • 35.  Time Radiation dose is proportional to exposure duration  Distance Radiation dose is inversely proportional to the square root of the distance from the patient
  • 36.  Shielding - Lead is the most common material used - A lead apron with an equivalent of 0.5mm of lead in front panel is mandatory - Lead in the back panel provides additional protection - Thyroid shield (0.5mm equivalence) is recommended to shield the sternum,upper breast and thyroid gland
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  • 38.  Shielding continued - Leaded eyeglasses with the side shields reduce the exposure to the eyes and may improve visual acuity - Recommended for staff with collar-badge doses approaching 15rem per year and for interventionalist’s training
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  • 40.  Shielding continued - Hands receive the highest radiation dose,but are relatively insensitive to radiation - Supplemental lead shielding to reduce exposure to scatter is available in the form of table mounted lead drapes,ceiling mounted lead acrylic shields and rolling lead acrylic shields
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  • 42.  Interventionalists commonly assigned 2 radiation badges - One on collar - Second underneath lead apron Lead apron reduces the radiation dose at the waist to 10% of dose at collar at 75kVp Effective dose equivalent best estimated by averaging the 2 dosimeters - Mean dose equivalent per procedure 4+/-2 millirem,highest doses were delivered to physicians in training
  • 43.  Women of child-bearing age should receive a pregnancy test prior to procedure  Current regulations restrict radiation dose to the embryo and fetus to 500millirem for the entire gestation and a monthly dose <50millirem  Pregnancy does not exclude working in the cardiac catheterization lab  Highest danger of fetal abnormalities is in the first trimester
  • 44.  Maturity lead aprons provide an additional 1mm of lead equivalence  Use of properly fitting wrap-around apron provides same protection to the fetus  Fetal radiation badge should be worn on the abdomen under the apron to record monthly fetal exposure