Sequential Analysis for the Patterns of the US Fatal Diseases and Injuries

1. Understanding the US
fatal disease and injuries
Group 6 Members:
Hilda Hadan
Jiahui Wang
Shiyu Zhang
Tracey Wanasukaphun

2. About the dataset
● The datasets we selected come from Centers for Disease Control and
Prevention.
● 2015, 2016 and 2006 as a comparison.
● Each dataset contains general information (e.g. place of death, date of death),
decedent information (e.g. gender, race, age, education, marital status, etc.),
underlying cause of death(e.g. diseases, incidents, etc.), injury conditions.
● Data pre-process: Dataset Parse, Missing Values, detect outliers, stack, etc.

3. Project Motivation & Objectives
1. What ICD-10 codes most commonly occur?
2. Which fatal diseases and injuries co-occur most often?
3. What are common sequences of fatal diseases and injuries, grouped by the leading
causes of death?
4. Analyze the sequence of co-occurrences and/or sequences changed across time
(2006 and 2016)

4. Our Methodologies
Methodology Explanation Tools
Association Analysis Discover rules that indicate the likely
occurrence of an item based on the
occurrences of other items in the transaction
SAS JMP Pro
Sequential Analysis Finding sequence patterns, associations,
correlations, or causal structures among sets of
items in transaction databases within the same
level
SAS Enterprise Miner
Market Basket Sequential analysis across Level of items SAS Enterprise Miner
Compare 2006 and 2015-16 Comparing the sequence changed from 2006 to
2015-16
R
Visualization JMP Pro, Python, R,
Tableau

5. ICD-10 Code
Source: https://en.wikipedia.org/wiki/ICD-10

6. Association Analysis (2015-2016)(JMP PRO)
Minimum Support=0.075, Minimum Confidence=0.3, Minimum Lift=1

7. Association Analysis (2015-2016)
(High Level)
➔ {Diseases of the circulatory system, Injury,
poisoning and certain other consequences
of external causes, External causes of
morbidity and mortality}
➔ {Diseases of the respiratory system,
External causes of morbidity and mortality}
➔ {Mental and behavioural disorders,
Diseases of the circulatory system}
➔ {Mental and behavioural disorders, Injury,
poisoning and certain other consequences
of external causes, External causes of
morbidity and mortality}
➔ {Diseases of the circulatory system,
External causes of morbidity and mortality,
Injury, poisoning and certain other
consequences of external causes}
(Low Level)
➔ {Unintentional poisoning, Mental and
behavioural disorders due to psychoactive
substance use, Poisoning by drugs,
medicaments and biological substances}
➔ {Unintentional poisoning, Poisoning by
drugs, medicaments and biological
substances, Toxic effects of substances
chiefly nonmedicinal as to source}
➔ {Head, Intentional self-harm}
➔ {Head, Unintentional falls}
➔ {Unspecified parts of trunk, limb or body
region, Effects of foreign body entering
through natural orifice ,Head}
➔
➔ {Poisoning by narcotics and
psychodysleptics,Accidental poisoning by
and exposure to narcotics and
psychodysleptics [hallucinogens] }

8. Association Analysis (2006)(JMP PRO)
Minimum Support=0.075, Minimum Confidence=0.3, Minimum Lift=1

9. Association Analysis (2006)
(High Level)
➔ {Diseases of the circulatory system,
External causes of morbidity and
mortality}
➔ {Injury, poisoning and certain other
consequences of external causes,
External causes of morbidity and
mortality}
➔ {Mental and behavioural disorders,
External causes of morbidity and mortality,
Injury, poisoning and certain other
consequences of external causes}
➔ {Diseases of the circulatory system, Injury,
poisoning and certain other consequences
of external causes, External causes of
morbidity and mortality}
(Low Level)
➔ {Unintentional poisoning, Poisoning by
drugs, medicaments and biological
substances}
➔ {Unintentional poisoning, Toxic effects of
substances chiefly nonmedicinal as to
source}
➔ {Poisoning by drugs, medicaments and
biological substances, Toxic effects of
substances chiefly nonmedicinal as to
source}
➔ {Head, Intentional self-harm}
➔ {Poisoning by narcotics and
psychodysleptics,Accidental poisoning
by and exposure to narcotics and
psychodysleptics [hallucinogens] }

10. J> T > W
1.Diseases of the respiratory system
2.Injury, poisoning and certain other
consequences of external causes
3.External causes
X> F > T
1.External causes
2.Mental and behavioural disorders
3.Injury, poisoning and certain other
consequences of external causes
I> J > S
1.Diseases of the circulatory system
2.Diseases of the respiratory system
3.Injury, poisoning and certain other
consequences of external causes
Sequential Analysis(2006) - High level
Lift Value > 1, Confident > 30%

11. X95/X74/X72> S01 > T14
1. X95 Assault by other and unspecified firearm discharge
X74: Intentional self-harm by other and unspecified firearm
discharge
X72: Intentional self-harm by handgun discharge
2. Open wound of head
3. Injuries of unspecified body region
X42 > F19 > T40
1. Accidental poisoning by and exposure to narcotics
and psychodysleptics
2.multiple drug use and use of other psychoactive
substances
3.Poisoning by narcotics and psychodysleptics by kind
of drugs
X42 > T40
1. Accidental poisoning by and exposure to narcotics
and psychodysleptics
2.Poisoning by narcotics and psychodysleptics by kind
of drugs
Sequential Analysis(2006)- Low level
Lift Value > 1, Confident > 30%

12. S > W
1. Injury, poisoning and certain
other consequences of external
causes
2.External causes
X7 > S01
1.Intentional self-harm by hanging,
strangulation and suffocation
2.Open wound of headX > T14
1. External causes
2.Injuries of unspecified body
region
W1 > W19
1.Falls
2.accidental fall
Market Basket Analysis 2006
40 Rules: Support % > 7.5%, Confident > 0.3%

13. F > T > W
1.Mental and behavioural disorders
2.Injury, poisoning and certain other
consequences of external causes
3.External causes
G > I > T
1.Diseases of the nervous system
2.Diseases of the circulatory system
3.Injury, poisoning and certain other
consequences of external causes
I > S
1.Diseases of the circulatory system
2.Injury, poisoning and certain other
3.consequences of external causes
G > I > S
1. Diseases of the nervous system
2.Diseases of the circulatory system
3.Injury, poisoning and certain other
consequences of external causes
Sequential Analysis(2015-16)- High level
Lift Value > 1, Confident > 30%

14. X72 > S01 > T14
1.Intentional self-harm by handgun discharge
2.Open wound of head
3.Open wound of unspecified body region
F11> T40 > T43
1.Use of opioids
2.Poisoning by narcotics and psychodysleptics
3.Poisoning by psychotropic drugs, not
elsewhere classified
F10 > T51 > X45
1.Use of alcohol
2.Open wound of forearm
3.Accidental poisoning by and exposure to alcohol
Sequential Analysis(15-16)- Low level)
Lift Value > 1, Confident > 30%

15. W1 > W19
1. Falls
2.Accidental fall
W > S
1.External causes
2. Injury, poisoning and certain other
consequences of external causes
S0 > S01
1.Injury (Head)
2.Open wound of head
S01 > X7
1.Open wound of head
2.Intentional self-harm
T50 > X/ X4/ T5/ T4
1.Poisoning by diuretics and other and unspecified
drugs, medicaments and biological substances
2. T4/T5 Poisoning by drugs, medicaments and
biological substances
X:Other external causes of accidental injury
X4:Accidental poisoning by and exposure to
noxious substances
Market Basket Analysis 2015-16
Support % > 7.5%, Confident > 0.3%

16. Comparison Analysis

17. Comparison Analysis
2006 2015-16