Vasopressors and inotropes

Vasopressors and Inotropes 1/27/10 Jason Begalke, D.O.

Adrenergic Receptor Physiology ,[object Object],[object Object],[object Object],[object Object]

Alpha-1 Adrenergic Receptors ,[object Object],[object Object],[object Object],[object Object]

Beta Adrenergic Receptors ,[object Object],[object Object],[object Object]

Dopamine Receptors ,[object Object],[object Object],[object Object]

Principles Of Use Of Vasopressors and Inotropes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Principles Of Use Of Vasopressors and Inotropes ,[object Object],[object Object],[object Object],[object Object]

Volume Resuscitation ,[object Object],[object Object],[object Object]

Selection and Titration ,[object Object],[object Object],[object Object]

Tachyphylaxis ,[object Object],[object Object]

Subcutaneous Drug Delivery ,[object Object]

Phenylephrine (Neosynephrine) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Norepinephrine (Levophed) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Epinephrine (Adrenalin) ,[object Object],[object Object],[object Object],[object Object],[object Object]

Dopamine (Intropin) ,[object Object],[object Object],[object Object],[object Object]

Dopamine (Intropin) ,[object Object],[object Object]

“Renal-dose” Dopamine ,[object Object],[object Object]

Dobutamine (Dobutrex) ,[object Object],[object Object],[object Object],[object Object]

Dobutamine (Dobutrex) ,[object Object],[object Object],[object Object]

Phosphodiesterase Inhibitors ,[object Object],[object Object],[object Object],[object Object],[object Object]

Vasopressin ,[object Object],[object Object],[object Object]

Vasopressin ,[object Object],[object Object],[object Object],1. Arginine Vasopressin in Advanced Vasodilatory Shock, Circulation. 2003; 107: 2313–2319. 2. Vasopressin versus Norepinephrine Infusion in Patients with Septic Shock, NEJM. 2008; 358:877-887. 3. Septic Shock – Vasopressin, Norepinephrine, and Urgency, NEJM. 2008; 358;954-956.

Vasopressin ,[object Object],4. Interaction of vasopressin infusion, corticosteroid treatment, and mortality of septic shock, Crit Care Med. 2009; 37; 811-818.

Complications Hypoperfusion ,[object Object],[object Object],[object Object]

Complications Dysrhythmias ,[object Object],[object Object],[object Object]

Complications Myocardial ischemia ,[object Object],[object Object]

Complications Local effects ,[object Object],[object Object],[object Object]

Complications Hyperglycemia ,[object Object],[object Object],[object Object]

Vasopressor Use in Septic Shock ,[object Object],[object Object],[object Object],[object Object]

SACiUCI Study ,[object Object],[object Object],[object Object]

Vasopressors and inotropes

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