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Manoj Saxena
General Manager
IBM Watson Solutions
Brief History of IBM Watson
R&D
Demonstration
Commercialization
Cross-industry
ApplicationsExpansion
New Division
IBM
Research
Project
(2006 – )
Jeopardy!
Grand
Challenge
(Feb 2011)
Watson
for Healthcare
(Aug 2011 –)
Watson
Industry
Solutions
(2012 – )
Watson
for Financial
Services
(Mar 2012 – )
business leaders don’t
have access to data
they need
of CIOs cited BI and
analytics as part of their
visionary plan
more likely that top
performers use business
analytics
of the world’s data
today is unstructured
of the world’s data was
created in the last two
years
connected devices help
generate 2.5 quintillion
bytes data / day
Businesses Are “Dying of Thirst in an Ocean of Data”
So Why Is It so Hard for Computers to Understand Humans
Person Organization
L. Gerstner IBM
J. Welch GE
W. Gates Microsoft
“If leadership is an art
then surely Jack Welch
has proved himself a
master painter during his
tenure at GE.”
Welch ran this?
 Noses that run and feet that smell?
 How can a house burn up as it burns down?
 Does CPD represent a complex comorbidity of lung cancer?
 What mix of zero-coupon, non-callable, A+ munis fit my risk tolerance?
Understands
natural language
and human
communication
Adapts and
Learns from
user selections
and responses
Generates
and evaluates
evidence-based
hypothesis
IBM Watson Brings Together Transformational
Technologies to Drive Optimized Outcomes
How Watson Works: DeepQA Architecture
Answer
Scoring
Models
Responses with
Confidence
Inquiry
Evidence
Sources
Models
Models
Models
Models
ModelsPrimary
Search
Candidate
Answer
Generation
Hypothesis
Generation
Hypothesis and Evidence
Scoring
Final Confidence
Merging & Ranking
Synthesis
Answer
Sources
Inquiry/Topic
Analysis
Evidence
Retrieval
Deep
Evidence
Scoring
Learned Models
help combine and
weigh the Evidence
Hypothesis
Generation
Hypothesis and Evidence
Scoring
Inquiry
Decomposition
1000’s of
Pieces of Evidence
100,000’s Scores from
many Deep Analysis
Algorithms
100’s
sources
100’s Possible
Answers
Multiple
Interpretations
Balance
& Combine
“Medicine has become too
complex. Only about 20% of
the knowledge clinicians use
today is evidence-based.”
Steven Shapiro
Chief Medical & Scientific Officer
University Pittsburgh Medical Center
Healthcare Is Beset with Some of the Most Complex
Information Challenges We Collectively Face
•Extract Symptoms from record
• Use paraphrasings mined from text to handle alternate
phrasings and variants
• Perform broad search for possible diagnoses
• Score Confidence in each diagnosis based on evidence
so far
• Identify negative Symptoms
• Reason with mined relations to explain away symptoms
(thirst is consistent w/ UTI)
• Extract Family History
• Use Medical Taxonomies to generalize medical
conditions to the granularity used by the models
•Extract Patient History
•Extract Medications
•Use database of drug side-effects
•Together, multiple diagnoses may best explain symptoms
•Extract Findings: Confirms that UTI was present
Most Confident Diagnosis: DiabetesMost Confident Diagnosis: UTIMost Confident Diagnosis: EsophagitisMost Confident Diagnosis: Influenza
Putting the Pieces Together at Point of Impact Can Be
Life Changing
Symptoms
UTI
Diabetes
Influenza
Hypokalemia
Renal failure
no abdominal pain
no back pain
no cough
no diarrhea
(Thyroid Autoimmune)
Esophagitis
pravastatin
Alendronate
levothyroxine
hydroxychloroquine
Diagnosis Models
frequent UTI
cutaneous lupus
hyperlipidemia
osteoporosis
hypothyroidism
Confidence
difficulty swallowing
dizziness
anorexia
fever
dry mouth
thirst
frequent urination
Family
History
Graves’ Disease
Oral cancer
Bladder cancer
Hemochromatosis
Purpura
Patient
History
MedicationsFindings
supine 120/80 mm HG
urine dipstick:
leukocyte esterase
urine culture: E. Coli
heart rate: 88 bpm
Symptoms
A 58-year-old woman presented to her primary care physician
after several days of dizziness, anorexia, dry mouth, increased
thirst, and frequent urination. She had also had a fever and
reported that food would “get stuck” when she was swallowing.
She reported no pain in her abdomen, back, or flank and no
cough, shortness of breath, diarrhea, or dysuria
A 58-year-old woman presented to her primary care physician
after several days of dizziness, anorexia, dry mouth, increased
thirst, and frequent urination. She had also had a fever and
reported that food would “get stuck” when she was swallowing.
She reported no pain in her abdomen, back, or flank and no
cough, shortness of breath, diarrhea, or dysuria
A 58-year-old woman presented to her primary care physician
after several days of dizziness, anorexia, dry mouth, increased
thirst, and frequent urination. She had also had a fever and
reported that food would “get stuck” when she was swallowing.
She reported no pain in her abdomen, back, or flank and no
cough, shortness of breath, diarrhea, or dysuria
Family History
Her family history included oral and bladder cancer in her
mother, Graves' disease in two sisters, hemochromatosis in one
sister, and idiopathic thrombocytopenic purpura in one sister
Patient History
Her history was notable for cutaneous lupus, hyperlipidemia,
osteoporosis, frequent urinary tract infections, three
uncomplicated cesarean sections, a left oophorectomy for a
benign cyst, and primary hypothyroidism, which had been
diagnosed a year earlier
Her medications were levothyroxine, hydroxychloroquine,
pravastatin, and alendronate.
MedicationsFindings
A urine dipstick was positive for leukocyte esterase and
nitrites. The patient given a prescription fo ciprofloxacin
for a urinary tract infection. 3 days later, patient reported
weakness and dizziness. Her supine blood pressure was
120/80 mm Hg, and pulse was 88.
IBM Watson Goes to Work in Healthcare
Support researchers and clinicians
in discovery of new cancer therapies
Assist physicians and care providers with
evidence based diagnosis and treatment
Genomic
Researcher
Analytics
Expert
Therapy
Designer
Care
Provider
Patient
Oncologist
Ultimate Goal: Become the Most Essential Company
1 in 3
individuals will die
from cancer
3X
rate cancer cost climbs vs. std.
health costs or 15-18% / yr.
20%
of cancer cases receive the wrong
diagnosis initially with some as high
as 44%
$263.8B
overall costs of cancer
in the US in 2010
✔
✔
✔
Source: American Cancer Society, National Health Institute
X
$$$$$$$$$$$$
$$$$$$$$$$$$
$$$$$$$$$$$$
$$$$$$$$$$$$
✔ ✔
✔
✔
IBM
+ +
Working Together to Beat Cancer
IBM
+ +Working Together to Beat Cancer
Cancer is an Insidious Disease and the Second Highest
Cause of Death
Demonstration
Watson Enables Three Types of Cognitive Services
Watson Enables Three Classes of Cognitive Services
 Leverage vast amounts of data
 Ask questions for greater insights
 Natural language inquiries
 e.g. Next generation Chat
 Find the rationale for given answers
 Prompt for inputs to yield improved responses
 Inspire consideration of new ideas
 e.g. Next generation Search  Discovery
 Ingest and analyze domain sources, info models
 Generate evidence based decisions with confidence
 Learn with new outcomes and actions
 e.g. Next generation Apps  Probabilistic Apps
How It Works: Watson Technology & Infrastructure
Dynamic Capacity
Automate and control
service provisioning
Flexible
Consumption
Support alternative
delivery and value
pricing models
Time to Value
Enable incremental
automation and
business agility
Hybrid Delivery
Extend & integrate
on-premise solution
with cloud offering
How It Works: Cloud Delivery and Outcome Based Pricing
1. Discovery
Workshops
(4-6 weeks)
2. Pilots
(6-12 Months)
3. Scale Out
(Ongoing)
Option A:
Deploy initial pilot
• Build
• Teach
• Run
Step 1:
 Identify
Candidate Use
Cases
 Assess Content
Availability
 Model Business
Value
Option B:
Put on Ready for
Progression Path
• Smarter Analytics
• Big Data
• Industry Solutions
Step 3:
• Add Users
• Add Geographies
• Expand Processes
Getting Started with Watson
1900 1950 2011
Tabulation Programmatic Cognitive
Search
Deterministic
Enterprise data
Machine language
Simple outputs
Discovery
Probabilistic
Big Data
Natural language
Intelligent Options
Punch Cards
Time Card Readers
Electronic Computation
Watson Is Ushering in a New Era of Computing…
Manoj Saxena General Manager IBM Watson Solutions
Manoj Saxena General Manager IBM Watson Solutions

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Manoj Saxena General Manager IBM Watson Solutions

  • 2.
  • 3. Brief History of IBM Watson R&D Demonstration Commercialization Cross-industry ApplicationsExpansion New Division IBM Research Project (2006 – ) Jeopardy! Grand Challenge (Feb 2011) Watson for Healthcare (Aug 2011 –) Watson Industry Solutions (2012 – ) Watson for Financial Services (Mar 2012 – )
  • 4. business leaders don’t have access to data they need of CIOs cited BI and analytics as part of their visionary plan more likely that top performers use business analytics of the world’s data today is unstructured of the world’s data was created in the last two years connected devices help generate 2.5 quintillion bytes data / day Businesses Are “Dying of Thirst in an Ocean of Data”
  • 5. So Why Is It so Hard for Computers to Understand Humans Person Organization L. Gerstner IBM J. Welch GE W. Gates Microsoft “If leadership is an art then surely Jack Welch has proved himself a master painter during his tenure at GE.” Welch ran this?  Noses that run and feet that smell?  How can a house burn up as it burns down?  Does CPD represent a complex comorbidity of lung cancer?  What mix of zero-coupon, non-callable, A+ munis fit my risk tolerance?
  • 6. Understands natural language and human communication Adapts and Learns from user selections and responses Generates and evaluates evidence-based hypothesis IBM Watson Brings Together Transformational Technologies to Drive Optimized Outcomes
  • 7. How Watson Works: DeepQA Architecture Answer Scoring Models Responses with Confidence Inquiry Evidence Sources Models Models Models Models ModelsPrimary Search Candidate Answer Generation Hypothesis Generation Hypothesis and Evidence Scoring Final Confidence Merging & Ranking Synthesis Answer Sources Inquiry/Topic Analysis Evidence Retrieval Deep Evidence Scoring Learned Models help combine and weigh the Evidence Hypothesis Generation Hypothesis and Evidence Scoring Inquiry Decomposition 1000’s of Pieces of Evidence 100,000’s Scores from many Deep Analysis Algorithms 100’s sources 100’s Possible Answers Multiple Interpretations Balance & Combine
  • 8. “Medicine has become too complex. Only about 20% of the knowledge clinicians use today is evidence-based.” Steven Shapiro Chief Medical & Scientific Officer University Pittsburgh Medical Center Healthcare Is Beset with Some of the Most Complex Information Challenges We Collectively Face
  • 9. •Extract Symptoms from record • Use paraphrasings mined from text to handle alternate phrasings and variants • Perform broad search for possible diagnoses • Score Confidence in each diagnosis based on evidence so far • Identify negative Symptoms • Reason with mined relations to explain away symptoms (thirst is consistent w/ UTI) • Extract Family History • Use Medical Taxonomies to generalize medical conditions to the granularity used by the models •Extract Patient History •Extract Medications •Use database of drug side-effects •Together, multiple diagnoses may best explain symptoms •Extract Findings: Confirms that UTI was present Most Confident Diagnosis: DiabetesMost Confident Diagnosis: UTIMost Confident Diagnosis: EsophagitisMost Confident Diagnosis: Influenza Putting the Pieces Together at Point of Impact Can Be Life Changing Symptoms UTI Diabetes Influenza Hypokalemia Renal failure no abdominal pain no back pain no cough no diarrhea (Thyroid Autoimmune) Esophagitis pravastatin Alendronate levothyroxine hydroxychloroquine Diagnosis Models frequent UTI cutaneous lupus hyperlipidemia osteoporosis hypothyroidism Confidence difficulty swallowing dizziness anorexia fever dry mouth thirst frequent urination Family History Graves’ Disease Oral cancer Bladder cancer Hemochromatosis Purpura Patient History MedicationsFindings supine 120/80 mm HG urine dipstick: leukocyte esterase urine culture: E. Coli heart rate: 88 bpm Symptoms A 58-year-old woman presented to her primary care physician after several days of dizziness, anorexia, dry mouth, increased thirst, and frequent urination. She had also had a fever and reported that food would “get stuck” when she was swallowing. She reported no pain in her abdomen, back, or flank and no cough, shortness of breath, diarrhea, or dysuria A 58-year-old woman presented to her primary care physician after several days of dizziness, anorexia, dry mouth, increased thirst, and frequent urination. She had also had a fever and reported that food would “get stuck” when she was swallowing. She reported no pain in her abdomen, back, or flank and no cough, shortness of breath, diarrhea, or dysuria A 58-year-old woman presented to her primary care physician after several days of dizziness, anorexia, dry mouth, increased thirst, and frequent urination. She had also had a fever and reported that food would “get stuck” when she was swallowing. She reported no pain in her abdomen, back, or flank and no cough, shortness of breath, diarrhea, or dysuria Family History Her family history included oral and bladder cancer in her mother, Graves' disease in two sisters, hemochromatosis in one sister, and idiopathic thrombocytopenic purpura in one sister Patient History Her history was notable for cutaneous lupus, hyperlipidemia, osteoporosis, frequent urinary tract infections, three uncomplicated cesarean sections, a left oophorectomy for a benign cyst, and primary hypothyroidism, which had been diagnosed a year earlier Her medications were levothyroxine, hydroxychloroquine, pravastatin, and alendronate. MedicationsFindings A urine dipstick was positive for leukocyte esterase and nitrites. The patient given a prescription fo ciprofloxacin for a urinary tract infection. 3 days later, patient reported weakness and dizziness. Her supine blood pressure was 120/80 mm Hg, and pulse was 88.
  • 10. IBM Watson Goes to Work in Healthcare Support researchers and clinicians in discovery of new cancer therapies Assist physicians and care providers with evidence based diagnosis and treatment Genomic Researcher Analytics Expert Therapy Designer Care Provider Patient Oncologist Ultimate Goal: Become the Most Essential Company
  • 11. 1 in 3 individuals will die from cancer 3X rate cancer cost climbs vs. std. health costs or 15-18% / yr. 20% of cancer cases receive the wrong diagnosis initially with some as high as 44% $263.8B overall costs of cancer in the US in 2010 ✔ ✔ ✔ Source: American Cancer Society, National Health Institute X $$$$$$$$$$$$ $$$$$$$$$$$$ $$$$$$$$$$$$ $$$$$$$$$$$$ ✔ ✔ ✔ ✔ IBM + + Working Together to Beat Cancer IBM + +Working Together to Beat Cancer Cancer is an Insidious Disease and the Second Highest Cause of Death
  • 13. Watson Enables Three Types of Cognitive Services
  • 14. Watson Enables Three Classes of Cognitive Services  Leverage vast amounts of data  Ask questions for greater insights  Natural language inquiries  e.g. Next generation Chat  Find the rationale for given answers  Prompt for inputs to yield improved responses  Inspire consideration of new ideas  e.g. Next generation Search  Discovery  Ingest and analyze domain sources, info models  Generate evidence based decisions with confidence  Learn with new outcomes and actions  e.g. Next generation Apps  Probabilistic Apps
  • 15. How It Works: Watson Technology & Infrastructure
  • 16. Dynamic Capacity Automate and control service provisioning Flexible Consumption Support alternative delivery and value pricing models Time to Value Enable incremental automation and business agility Hybrid Delivery Extend & integrate on-premise solution with cloud offering How It Works: Cloud Delivery and Outcome Based Pricing
  • 17. 1. Discovery Workshops (4-6 weeks) 2. Pilots (6-12 Months) 3. Scale Out (Ongoing) Option A: Deploy initial pilot • Build • Teach • Run Step 1:  Identify Candidate Use Cases  Assess Content Availability  Model Business Value Option B: Put on Ready for Progression Path • Smarter Analytics • Big Data • Industry Solutions Step 3: • Add Users • Add Geographies • Expand Processes Getting Started with Watson
  • 18. 1900 1950 2011 Tabulation Programmatic Cognitive Search Deterministic Enterprise data Machine language Simple outputs Discovery Probabilistic Big Data Natural language Intelligent Options Punch Cards Time Card Readers Electronic Computation Watson Is Ushering in a New Era of Computing…