2. Disclaimer
This release contains forward-looking statements that are exclusively related to the prospects of the business, its operating and
financial results, and prospects for growth. These data are merely projections and, as such, based exclusively on our management's
expectations for the future of the business and its continued access to capital to fund its business plan. These forward-looking
statements substantially depend on the market conditions, government regulations, competitive pressures, the performance of the
Brazilian economy and the industry, among other factors, as well as the risks shown in our filed disclosure documents, and are
therefore subject to change without prior notice.
In addition, unaudited information herein reflects management's interpretation of information taken from its financial statements and
their respective adjustments, which were prepared in accordance with market practices and for the sole purpose of a more detailed
and specific analysis of our results. Therefore, these additional considerations and data must also be analyzed and interpreted
independently by shareholders and market agents, who should carry out their own analysis and draw their own conclusions from the
information reported herein. No data or interpretative analysis provided by our management should be treated as a guarantee of
future performance or results and are merely illustrative of our directors' vision of our results.
Our management is not responsible for compliance or accuracy of the data from this report, which must be considered as for
informational purposes only, and should not override the analysis of our audited consolidated financial statements for purposes of a
decision to invest in our stock, or for any other purpose.
2
5. Brazil
22.4 bn
44%
Mexico
10.0 bn
19% Argentina
5.0 bn
13%
Colombia
4.7 bn
9%
Chile
2.8 bn
5%
Other
6.5 bn
13% -3.6%
1.9%
3.7%
3.9%
5.1%
The largest market in Latam, with the highest real growth
Source: IQVIA World Review Conference (Jun/2019); LATAM Market LTM 1Q195
Latin American Market (USD) Real Growth 2018-2019
6. Fast-growing market, above Emerging Markets average
Source: IQVIA Market Prognosis, Sep/2018; IQVIA Institute, Dec/20186
5%
5%
6%
6%
7%
7%
8%
10%
11%
RoW
UK
Global
China
USA
EM
Brazil
Russia
India
Forecasted 2019-23 CAGR
14. Our history
14
2007 - 2011 2012 - 2016 2017 - 2021
Industry
Consolidation
Business
Restructuring
Pharma
Focus
Acquisitions of brands
and companies at
attractive valuations:
Development of the go-
to-market platform:
• Largest and most productive
Brazilian manufacturing site
• Highest production volume
• Lowest cost producer
• Most productive
sales force at physicians
• Lowest cost media buying
• Largest field
force at store level
(>70% direct access)
• Focus on the retail pharma
market
• Higher resilience
• Underpenetrated markets
• Untapped demand
• Diversified portfolio
• Higher Returns (ROIC/ROE)
Focus on most attractive
pharma sector:
~4x Total
Return* in 10
years since
IPO
123%
376%
IBOV HYPE3
* Total return considers
dividends
15. Consumer
Health
36%
RX/OTX2
43%
Generics
12%
9%
2018 Portfolio: Strong relevance of branded products
Note: 1OTC products and sweeteners; ²Branded Prescription Products and Branded Generics
Source: Company financials
15
Net Revenues: R$3.7bn
Gross Margin: 71.6%
Dermo
Branded
Products
88%
Consumer
Health1
36%
16. 2018 Revenue breakdown per brand
16
7.1%
4.7%
4.3%
4.1%
3.6%
3.3%
3.2%
2.7%
2.6%
2.4%
62.0%
RX
RX
Dermo
RX
Consumer Health
RX
Consumer Health
Consumer Health
Top 10
Brands:
~38% of
sales
Consumer Health
RX
Source: Company financials
17. 2018 Revenue Breakdown by area
Pain &
Fever
22% 23%
Dermo
17%
Resp3
10%
9%
4%
GI5 2%
Other 3%
Orthopedics
GP2 &
Pediatrics
RX1 and Dermo
Women/Men’s Health 4%
CNS4 2%
Endocrinology 4%
Cardiology
Note: 1Branded Prescription and Branded Generics; ²General Practice; ³Respiratory System; 4Central Nervous System; 5Gastrointestinal
Source: Company financials
17
18. 2018 Revenue Breakdown by area
Source: Company financials18
Vitamins
General
Practice
Nutritionals
31% 23%
18%
12%
12%
4%
Other
Pain &
Fever
Flu &
ColdGI
Orthopedics
Nutritionals &
Nutraceuticals
Consumer Health
19. 3 Business Units with growth, profitability and innovation
targets
19
Hypera Pharma is internally divided into 3 Business Units according to demand generation
(POS, Doctors and Media)
Consumer/MediaDoctorsTrade/POS
20. 2018 Revenue and Market Position per Business Unit
Note: 1OTC products and sweeteners; ²Ex-patents products promoted to physicians; ³Pure and Branded Generics promoted in the POS
Source: Company financials; IMS Health Dec/17
20
Branded
Prescription²
40%
30%
30%
#1 Hypera Aché NC Farma
#2 Sanofi Eurofarma Hypera
#3 GSK Sanofi Cimed
#4 Takeda Novartis Sanofi
#5 Pfizer Hypera Eurofarma
Ranking
2018 Revenue Breakdown
Branded
Prescription
Generics
and Similars
Consumer
Health
Consumer Health1
Generics and
Similars³
21. R$100mi+ Power Brands
21
49 years 57 years
10 years 18 years
24 years
15 years
57 years
104 years
34 years
19 years
18 years
11 Power Brands
(Brand history)
22. How we sell: Diversified distribution
22
Transfer
Order
30%
• Continental country
(27 states; ~200mm people)
• 28 larger chains
• ~230 distributors
Fragmented distribution
36%
Direct
Channel
Indirect
Channel
34%
DistributorRetailer
Warehouse
Distributor
invoices&delivers
Hypera
takestheorders
75,300 Stores
Hypera reaches 100% of POS in Brazil
23. How we manufacture: Large scale facilities in Anápolis
23
~320,000 m2 land ~120,000 m2 constructed area ~3,700 employees
Distribution
Center
Solids/
Raw
Materials
Quality
Control
Aerosol
Efervecent
Dermo
Liquids
Semisolids
Injectables
R&D
PenicilinSolids
Semisolids
Liquids
R&D
Production Capacity per year:
+ 17 billion units of solids
+ 40 million units of injectable medicines
+ 330 million units of liquids, creams, oils and lotions
Anápolis
24. How we innovate: Unique innovation structure in Brazil
25
• Maintenance of existing
structure
• Focus on improving and
adapting the portfolio
• Laboratories for
Pharma
R&D - Anápolis
• Launched in 2017
• Chemists, pharmacists,
and Ph.D professionals
• Laboratories for
Pharma, Dermo and
Nutraceuticals
• State-of-the-art
equipment
R&D - Hynova
Consumer Insights
Center
• Lots in semi-industrial
size
Pilot plant
• Evaluation of the
performance of products
and packaging based on
consumer acceptance and
preference
Capacity
4x higher
25. Innovation in the pharmaceutical industry
26
Similar & Generics
Specific and
phytotherapeutics
New associations
New technologies
New pharmaceutical
forms
New drugs
Biotechnology
White spaces Incremental Radical
Low hanging fruits
Moderate risk and
development process
Global competition
High investment and long
process
26. 27
How we innovate: R&D KPIs
R&D
Investments in
2018
4.9%
of Revenues
Largest
Innovation Hub
in Latin
America
6laboratories
Capacity of
more than 20
pharmaceutical forms
300
people
150simultaneous
Projects
~R$70 million
in infrastructure
Medicines Dermocosmetics
And food
60 35
in R&D
29Patents
Submissions pear year
Note: Considers total R&D investments of the year (Expenses and Capitalization), excluding the “Lei do Bem” incentives
Source: Company financials
27. How we innovate: Increasing the commitment to R&D
Note: Considers total R&D investments of the year (Expenses and Capitalization), excluding the “Lei do Bem” incentives
Source: Company financials
28
1.7%
2.8%
4.0%
4.9%
2015 2016 2017 2018
R&D / Net Revenues
+3.2pp
28. How we innovate: Increasing importance of innovation
Source: Company Financials (% of Net Revenues from products launched over the past 5 years)29
16%
19%
23%
24%
28%
30%
2013 2014 2015 2016 2017 2018
Innovation Index (% Net Revenue) Target: 35%
31. Strategic Plan
Key objectives:
32
• Grow 2-3p.p. above the market in the medium term, boosted by
innovation and excellence in execution
• Maintain profitability
• Finance organic growth with operating cash flow
• Maintain cash distribution to shareholders
• Maintain net debt close to zero
32. Performance drivers
33
Execution
Innovation
• Commercial
productivity increase
• Launches execution
2018 2019 2020 2021+
Growth acceleration from 2020 on
• Better return of
marketing
investments
• Better operating
efficiency
• Working capital
efficiency
• Pipeline increase
• Strengthening
partnerships
33. 34
Pipeline Evolution
# of Projects
#Pipeline dec-2018#Products launched New projects#Pipeline dec-2017
278
70
130
338
34. 35
Pipeline breakdown per Business Unit
% of Gross Revenue in year 5
Consumer
Health
19%
Branded
Prescription
60%
Similars &
Generics
21%
338
projects
35. Pipeline by type of innovation
% of Gross Revenue in year 5
36
53% related to incremental innovation and 47% portfolio expansion
Note: Weighted 5-Year Gross Revenue - Launch: 90%, Anvisa: 80% (R&D) and 85% (BD), Development: 65%, Contract: 75%, Waiting Queue and Negotiation 50%
White
Spaces
38%
New Combination
26%
New
Technologies
28%
Patented
9%
36. Pipeline by Therapeutic area
37
Pain/Analgesics
16%
Allergy/Resp/
Otorrino
15%
Dermo
9%
GP
21%
GI
9%
CNS
16%
Cardio/Endocrino
13%
60%
of the pipeline
for treatment
of chronic diseases
Pipeline – Branded Prescription
% of Gross Revenue in 5th year
37. Products launched in 2018
# of products
38
Brand Extensions
New Categories
White Spaces
Low Complexity
High Complexity
Lançamentos 2018
70
43. Financial Highlights
44
2.8
3.0
3.2
3.5
3.7
2014 2015 2016 2017 2018
912 950
1,092
1,233 1,319
2014 2015 2016 2017 2018
Net Revenues
R$ bn
EBITDA
R$ mm
Net Income
R$ mm
338 346
647
1,112 1,135
2014 2015 2016 2017 2018
CAGR
7.7%
CAGR
9.6%
CAGR
35.4%
Source: Company Financials
44. 2018 Results (R$ million)
Note: ¹2018 vs. 2017; ²Continuing Operations; ³in R$ per share
Source: Company Financials
45
GROSS PROFIT
R$2,665.3 +3.6%1|
R$1,318.7 +7.0%1
EBITDA2
|
NET INCOME2
R$1,135.4 +2.2%1|
EPS2,3
R$1.80 +1.9%1|
NET REVENUES
R$3,724.3 +6.4%1|
GROSS MARGIN
71.6% -190bps1|
EBITDA MARGIN2
35.4% +20bps1|
NET INCOME2
30.5% -130bps1|
45. Cash Flow and Debt
Note: Financing Cash Flow net of interest from financial investments
Source: Company Financials
46
1,522 1,647
1,065
1,067
(128) (91)
848
(88)
(633)
(582)
Gross Cash
2017
Operating Cash
Flow
CAPEX Intangibles Free Cash Flow
2018
Financing Cash
Flow
Dividends Gross Cash
2018
Gross Debt Net Cash 2018
+14.4%
vs 2017
+17.6%
vs 2017
0,8x
EBITDA
46. R$0.50
R$0.65
R$0.92
R$0.97
2016 2017 2018 2019
Dividends/IOC
Note: It considers the dividends paid in the respective periods; Dividend Yield calculated based on the price of June 18, 201947
Dividend Yield: 1.9% 2.4%
CAGR
25%
2.6%
R$ per share
3.4%
47. 7.2%
14.0%
2016 2018
15.4%
18.9%
2016 2018
ROE – Return on Equity ROIC – Return on Invested Capital
ROE & ROIC
Note: ROE calculation is a result of the division of Continuing Operations Consolidated Net Income by the Consolidated Shareholders' Equity quarterly average of the year. ROIC calculation is
a result of the division of Continuing Operations Consolidated NOPAT (Cash Taxes) by the quarterly invested capital average of the year, excluding assets and liabilities for sale.
48
48. 20%
15%
65%
Founder
Free Float
Maiorem
Ownership and listings
Note: ¹2018 ²May/2019 ³June/2019
Source: B3; Company data
49
Listings
• Sao Paulo Stock Exchange: - HYPE3
- BRHYPEACNOR0
• Indexes with Hypera:
Ownership structure
Controlling
Group
35%
• Trade volume¹: 2.0 MM shares/day
• ADR (HYPMY)²: 8.7 MM shares outstanding
• IBOVESPA Index Ranking³: 36/65
• Market Cap³: R$18.2bn (USD4.7bn)