Weekly News Wrap-Up on Health Care Industry (Europe, North America, Asia/Pacific) showing the latest development of most striking fundamental economic and financial news

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Focus on Europe
Focus on North America
Focus on Asia Pacific
AstraZeneca announced that benralizumab achieved the primary endpoint in two pivotal Phase III
registrational trials (SIROCCO and CALIMA). (pharmpro.com)
Eurofins Scientific sig ed a ag ee e t to a ui e E o a’s food, ate a d pha a euti al testi g
business in the UK & Ireland for approximately $26 million. (businesswire.com)
Grifols has invested $50 million for a 20% stake in diagnostics and laboratory testing firm Singulex,
granting Grifols an exclusive license to its single-molecule counting technology. (genomeweb.com)
Novartis announced changes to focus its Pharmaceuticals Division by creating two business units
reporting to the CEO: Novartis Pharmaceuticals and Novartis Oncology. (streetinsider.com)
Qiagen extended the offer period for the acquisition of Exiqon. The company published a conditional,
voluntary public tender offer for the shares in Exiqon. (prnewswire.com)
Smith & Nephew is selling its gynecology business for about $350 million to Medtronic. It expects to
complete the sale in July and will start a $300 million share buyback program shortly after. (wsj.com)
Weekly News Wrap-Up: HEALTH CARE Industry
No. 12
2016-05-21
Allergan AstraZeneca Celgene Chugai Eurofins Scientific Grifols Johnson & Johnson
Medtronic Mylan Novartis Qiagen Ryman Healthcare Smith & Nephew Sysmex
SPOTLIGHT
COMPANY NEWS
Allergan said it had positive results in two trials of its Oculeve Intranasal Tear Neurostimulator,
OCUN-OO9 and OCUN-010, after both met their primary endpoints. (marketwatch.com)
Celgene hands over a $200 million upfront payment for its collaboration with Agios to start a new
pipeline of drugs that focuses in on metabolism pathways for immuno-oncology. (fiercebiotech.com)
Johnson & Johnson announced a collaboration with HP Inc. The collaboration is focused on using 3D
printing technologies to create better health care outcomes at reduced costs. (prnewswire.com)
Medtronic agreed to help promote Mazor Ro oti s’ guida e s ste used du i g spi al su ge ies
and will take an equity stake of up to 15 percent in the company. (bloomberg.com)
Mylan agreed to buy skin drug assets from Renaissance Acquisition for $950 million in cash up front
and up to $50 million in future payments to complement its existing products. (bloomberg.com)
Chugai announced that the results of the Japanese phase III study (J-ALEX) of Alecensa will be
presented at the American Society of Clinical Oncology (ASCO). (businesswire.com)
Ryman Healthcare has posted another record full-year profit, rounding out 14 straight years of
earnings growth. Its net profit jumped 26% to $305 million. (nzherald.co.nz)
Sysmex announced its first RAS biomarker testing site in France opening at the Biopathology
department of the Institut de Cancérologie de Lorraine, Nancy. (prnewswire.com)

2. Contact: Harald Schelenz Linkedin: https://de.linkedin.com/in/haraldschelenz
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Regional Comparison
Focus on Europe
99%
100%
101%
102%
2016-05-16 2016-05-17 2016-05-18 2016-05-19 2016-05-20
Europe North America Asia/Pacific
Ha i g a look at a regio al split up of the orld’s iggest listed health are o pa ies, one can see a
quite similar development in all regions which results in a combined growth rate of +1.2%. The
leading region is Europe with an increase of +1.3% this week, although its one year performance
reaches -15.1%. North America shows +1.2% and Asia/Pacific +0.9% on a weekly basis.
Weekly News Wrap-Up: HEALTH CARE Industry
No. 12
2016-05-21
AstraZeneca BTG Genmab GlaxoSmithKline Ipsen
Merck Recordati Smith & Nephew Sonova Stada
SPOTLIGHT
FINANCIAL MARKET NEWS
The strongest performer from Europe in the weekly performance ranking is Genmab with an increase
of +12.0% while its one year performance reaches +83.6%. Second is BTG with a value gain of +9.7%
on a weekly basis though it shows a negative development of -17.3% on a yearly basis.
Regardi g this eek’s lo perfor ers fro Europe, the orst de elop e t experie ed Sonova with
a decrease of -4.2%, while its one year change shows a decline of -10.9%. In second place is Ipsen
with a loss of -1.4% on a weekly basis, whereas its one year performance reaches +6.3%.
top 5 companies closing price 1 week change 1 year change 1 week'shigh 1 week'slow 1 year'shigh 1 year'slow
Genmab 151.99 +12.00% +83.62% 152.45 135.51 145.15 67.98
BTG 8.22 +9.74% -17.33% 8.23 7.38 10.16 7.05
Merck 87.02 +6.05% -13.00% 87.20 81.63 102.19 70.71
Stada 44.21 +5.69% +33.87% 44.31 41.53 44.31 28.07
Recordati 24.71 +5.50% +29.77% 25.18 23.29 25.18 17.72
flop 5 companies closing price 1 week change 1 year change 1 week's high 1 week's low 1 year's high 1 year's low
Sonova 116.44 -4.28% -10.93% 124.29 112.94 140.05 100.91
Ipsen 53.30 -1.45% +6.33% 54.22 53.14 62.30 47.13
Smith & Nephew 16.45 -1.20% -6.95% 16.99 16.35 18.66 14.95
GlaxoSmithKline 18.62 -1.16% -7.79% 18.99 18.42 21.00 16.65
AstraZeneca 50.97 -1.15% -17.42% 51.58 49.75 65.60 48.56
Index closing price 1 week change 1 year change 1 week's high 1 week's low 1 year's high 1 year's low
STOXX® Europe 600
Health Care
718.28 +1.33% -15.16% 718.47 704.31 876.66 654.95
STOXX® North America 600
Health Care
812.17 +1.23% -11.28% 815.12 800.39 966.34 730.68
STOXX® Asia/Pacific 600
Health Care
443.27 +0.97% +10.95% 447.46 437.88 454.36 349.32
STOXX® Global 1800
Health Care
716.74 +1.24% -10.85% 718.41 705.14 842.76 647.94