GLUP Montecchio 24-9-10

1. Functional Brain Imaging applied to bladder control

2. The new ( “ brain “ ) urodynamics

5. fMRI BOLD

7. f-MRI (1.5 - 3 Tesla )

8. Esempi di compito

9. 1 - Subject lies in the scanner

10. 2 - Task is performed ( bladder filled manually or through distant urodynamic equipment)

11. 3 - Scanner captures and process brain images

13. How the brain works ?

19. POSITRON EMISSION TOMOGRAPHY (PET) SCANS DURING BLADDER FILLING Pons Peri-aqueductal grey

21. Insula activity during bladder filling

27. MICTURITION Animated Work-up Model

28. Bladder Filling Kavia and Fowler 04 Courtesy CJF

29. Micturition Kavia and Fowler 04 Courtesy CJF

30. PMC S2-4 in cauda equina pelvic & pudendal ns

31. Brain Imaging & Micturition Literature to date

32. Poor Bladder Control ( urgency & DO) Rosenberg LJ , Griffiths DJ, Resnick DM , J.Urol, 2005

33. DO &Urgency as different entities (Tadic ,2009)

34. STRESS INCONTINENCE Neuroplastic Changes after PFM Training Di Gangi H , 2009

37. BRAIN and BLADDER From Barrington cats to human Functional Brain Imaging Giancarlo Vignoli Unità di Urodinamica & Uroginecologia Casa Madre Fortunata Toniolo Bologna

41. The nineties Neuroscience

45. Brain Imaging sections

47. Bladder “ noise “ Structures involved ( Fry C , ICI 2008)

48. Application of Functional Imaging to Pathophysiological Conditions