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IAEA
International Atomic Energy Agency
Slide set of 52 slides based on the chapter authored by
J. R. Cunningham and D. R. Dance
of the IAEA publication (ISBN 978-92-0-131010-1):
Diagnostic Radiology Physics:
A Handbook for Teachers and Students
Objective:
To familiarize students with the physics of events that occur when
photons and electrons interact with matter
Chapter 2: Interactions of Radiation
with Matter
Slide set prepared
by E.Okuno (S. Paulo, Brazil,
Institute of Physics of S. Paulo University)
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 2
Chapter 2. TABLE OF CONTENTS
2.1. Introduction
2.2. Interactions of photons with matter
2.3. Photon attenuation coefficients
2.4. Interactions of electrons with matter
2.5. Data sources
IAEA
2.1. INTRODUCTION
This chapter deals with the physics of events that occur
when photons and electrons interact with matter. These
are the radiations that are important for diagnostic
radiology, and only those interactions which result in
their attenuation, absorption and scattering are dealt with
The energy range used for diagnostic radiology is
generally on the boundary between classical and
quantum physics and following the “Complementarity
Principle”, the numerical details of the interactions will
be treated by classical reasoning where that is
appropriate and by quantum mechanical considerations
where that gives superior results
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 3
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 4
The interaction of photons and electrons, as they
traverse matter, are stochastic and obey the laws of
chance, although, with very different behaviour:
• Electrons experience large numbers of interactions
and in general gradually lose energy until they are
stopped. This is expressed in terms of electron range
and material stopping powers
• Photons in general have none, one or a few
interactions and are exponentially attenuated
Photon interactions are expressed in terms of
cross-sections for individual interactions and
attenuation coefficients for passage through bulk media
2.1. INTRODUCTION
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If there are Φ photons randomly directed at area A, that
contains n targets, each with area σ, the expected
number of interactions ∆Φ between photons and
targets will be ( )
A
n σ
Φ
=
∆Φ
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 5
2.2. INTERACTIONS OF PHOTONS WITH MATTER
The probability of a single photon incident on a
slab of material of area A, that contains one
target of cross-sectional area σ, interacting with
the target will be the ratio of the two areas: σ/A
Another way of saying this is that the probability of a
projectile making a hit is n (σ/A), which is just the
fraction of the area that is blocked off by the targets
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 6
2.2. INTERACTIONS OF PHOTONS WITH MATTER
Changing now the targets to: atoms, their
cross-section would be an atomic cross-section
This wouldn’t be an actual area of the atom, but
would be an effective area – effective for an
interaction between the photon and the atom that is
being considered
Cross-sections are frequently represented by
the symbol σ and conventionally expressed in
a unit of area called the barn (b)
1 barn = 10-28 m2
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 7
2.2. INTERACTIONS OF PHOTONS WITH MATTER
There are four fundamental X-ray interactions that we need to
consider; each can be associated with a specific cross-section
The first three of these interactions are important in the
diagnostic energy range up to 150 keV
Pair and triplet production are only important at much higher
energies and are only treated here for completeness
Interaction Cross-section
photoelectric effect τ
coherent scattering σcoh
incoherent scattering σincoh
pair and triplet production κ
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 8
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.1. Photoelectric Effect
K
L
M
N
before collision
hν
In the photoelectric effect the incident photon interacts
with an atom and disappears. A photoelectron is ejected
The photoelectric effect can only take place if the photon energy
hν > Es (binding energy)
K
L
M
N
after collision
photoelectron
T = hν - Es
The most probable electron shell to lose an electron is the one that
satisfies this constraint and has the highest binding energy
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 9
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.1. Photoelectric Effect
Calculation of the probability of the interaction is very complicated
and quantum mechanics is required
In the diagnostic energy range up to 150 keV, the photoelectric
effect cross-section per atom, τ, is approximately given by:
k is a constant
Z is the atomic number
n is an exponent in the range 3.6-5.3, being largest
for low atomic numbers
m is an exponent in the range 2.5-3.5, again being
largest for low atomic numbers
A typical dependence of τ in the diagnostic photon energy range is:
( )3
4
hv
Z
∝
τ
( )
( )m
n
hv
Z
k
Z
h =
,
ν
τ
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 10
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.1. Photoelectric Effect
Atomic photoelectric cross sections for
copper, molybdenum and tungsten
For tungsten, the discontinuity seen at
69.5 keV represents the effect of the K
shell. At an energy just less than this,
the cross section is 6.4 x 102 b/atom,
while just above this energy, the
coefficient is 3.3 x 103 b/atom. This
represents a sudden increase in
cross-section of about a factor of five
when the photon energy increases
above that of the K shell (K-edge)
Thus the major contribution to the
cross-section above the K-edge
comes from interactions with the two
K-shell electrons
The sharp discontinuities correspond to the positions of the
absorption edges for the different materials, which increase in
energy with increasing atomic number and shell binding energy
W K-edge
1 10 100
100
102
104
106
108
Cu
W
Mo
Photon Energy (keV)
τ
(b/atom)
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 11
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.2. Thomson Scattering
dΩ
θ
dV
Incident photon
Scattered photon
A photon incident on a small volume
element dV is scattered through angle
θ into the solid angle element dΩ
is the differential cross section
J.J. Thomson gave the first treatment of the scattering
of photons by electrons in the very early years of the
20th century
The probability that the photon
will interact and be scattered
into solid angle dΩ is
proportional to: Ω
Ω
d
d
dσ
Ω
d
dσ
The total cross section is
obtained by integrating over all
solid angles:
∫ Ω
Ω
= d
d
dσ
σ
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 12
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.2. Thomson Scattering
Thomson’s derivation of the scattering of a photon by a
single free electron at rest is based on classical physics
and results in a description that is only meaningful at the
low energy limit of this interaction
r0 is “classical radius of the electron”
k is a proportionality constant from Coulomb’s law
e is the charge on the electron
m0 is the rest mass of the electron
c is the speed of light
m
10
81794
.
2
15
2
0
2
0
−
×
=
=
c
m
e
k
r
Thomson showed that the differential
cross section, at scattering angle θ, is
given by :
( )
θ
σ 2
2
0
cos
1
2
d
d
+
=
Ω
r
Th
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 13
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.2. Thomson Scattering
This equation predicts that the same
amount of energy will be scattered
forward as backward, and also that the
energy scattered at right angles will be
half this amount. Except at low energies,
this result does not agree with
observation or with the predictions made
by quantum mechanics
Total cross-section
Differential cross-section
σTh is constant, predicting that the classical scattering
probability is independent of electromagnetic radiation energy
This, of course, is not correct
( )
θ
σ 2
2
0
cos
1
2
d
d
+
=
Ω
r
Th
( ) 2
30
2
0
0
2
2
0
m
10
x
52
.
66
3
8
d
sin
cos
1
2
2
−
=
=
+
= ∫
r
r
Th
π
θ
θ
θ
π
σ
π
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 14
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.3. Coherent (Rayleigh) Scattering
In reality the photon is scattered collectively by the
atomic electrons which are not free, and their proximity
to one another is not very different from the wavelength
of the radiation
In deriving the expression for Thomson scattering it was
assumed that the electron was free, alone and at rest
In coherent scattering essentially no energy is lost by the
photon as it transfers momentum to the atom and is
scattered through angle θ
The scattering by the different electrons is in phase and
the resultant angular distribution is determined by an
interference pattern which is characteristic of the atom
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 15
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.3. Coherent (Rayleigh) Scattering
The differential cross section is then given by:
is the Thomson differential scattering coefficient and
F is known as the coherent form factor
It may be calculated using quantum mechanical
models
λ is the wavelength of the incident photon. The
parameter x is proportional to the transfer of
momentum between the initial and scattered photon
directions
( )
Z
x
F
Th
coh
,
d
d
d
d 2
Ω
=
Ω
σ
σ
d
Ω
d
Th
σ
( )
λ
θ 2
sin
=
x
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 16
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.3. Coherent (Rayleigh) Scattering
Variation of the normalized form factor
F/Z for coherent scattering with the
momentum transfer parameter x
Data from Hubbell and Øverbø, J Phys Chem Ref Data
8, 69-106 (1979)
0.01 0.1 1 10
0.00
0.25
0.50
0.75
1.00
C
Fe
Pt
x (Å-1
)
Normalized
form
factor
(F/Z)
For scattering in the forward
direction all the atomic electrons
act together, and F is equal to the
atomic number and the differential
cross section depends upon Z2
However, for a given value of the
scattering angle, the normalized
coherent form factor F/Z, increases
with increasing atomic number
As the scattering angle increases,
F decreases because it becomes
increasingly difficult for all the
electrons to scatter in phase
without any energy transfer
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 17
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.4. Compton scattering by free electrons
Compton Scattering, like Thomson scattering,
is the interaction between electromagnetic
radiation and a free electron, but in this case
there is an energy transfer to the electron
Both the photon and the electron must be
considered as particles
The energy range is such that relativity and
quantum mechanics must be used to derive
expressions for the cross section
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 18
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.4. Compton scattering by free electrons
θ
ϕ
scattered photon
hν’
p’ = hν’/c
incident photon
hν
p = hν /c
recoil electron
Te
pe
Using conservation of energy and momentum
Compton relations can be derived:
( )
θ
α
ν
ν
cos
1
1
1
−
+
=
′
h
h
2
0c
m
h
α
ν
=
( ) 





+
=
2
tan
1
cot
θ
α
ϕ
( )
( )
θ
α
θ
α
ν
ν
cos
1
1
cos
1
−
+
−
=
′
−
= hv
h
h
Te
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 19
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.4. Compton scattering by free electrons
10
10
20
20
50
50
100
100
Incident photon energy (keV)
Scattered
photon
energy
(keV)
( )
θ
α
ν
ν
cos
1
1
1
−
+
=
′
h
h
( )
( )
θ
α
θ
α
ν
ν
cos
1
1
cos
1
−
+
−
=
′
−
= hv
h
h
Te
In the diagnostic energy range
is small, and as a
consequence the energy transfer
to the recoil electron is also
small, being zero in the forward
direction and taking its largest
value when the photon is
backscattered
2
0c
m
h
α
ν
=
For 20 keV, 50 keV and 100 keV
incident photons, the maximum
energy transfers to the recoil
electron are:
1.5 keV, 8.2 keV and 28.1 keV
respectively
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 20
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.4. Compton scattering by free electrons
The cross-section for the
scattering of a photon, with
energy hν through a given
angle θ, was first derived in
1928 by Klein and Nishina
using the Dirac theory of the
electron
This cross-section reduces to the Thomson
cross-section when α → 0 (that is hν’/ hν → 1)
0 50 100 150
0.0
0.1
0.2
0.3
0.0
0.1
0.2
0.3
dσ/dΩ
dσ/dθ
Scattering angle (degrees)
Photon scattering angle (degree)
Compton differential cross-sections
for scattering of 70 keV photons
(b/rad)
(b/sr)
The expression for the differential
cross-section for scattering of
photons by a single free electron
is:
( )






+
−
+
−
+






−
+
=
]
cos
1
)][
cos
1
(
1
[
cos
1
1
)
cos
1
(
1
1
2
2
2
2
θ
θ
α
θ
α
θ
α
KN
f
( ) KN
KN
f
r
θ
σ 2
2
0
cos
1
2
d
d
+
=
Ω
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 21
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.4. Compton scattering by free electrons
The total Compton cross-section (probability of
interaction per electron) for a photon of energy hν, is
obtained by integrating the differential cross section
over solid angle. The result is:
( ) KN
KN
f
r
θ
σ 2
2
0
cos
1
2
d
d
+
=
Ω
( )
( ) ( ) ( )
( ) 





+
+
−
+
+







 +
−
+
+





 +
= 2
2
2
0
2
1
3
1
2
2
1
ln
2
1
ln
2
1
1
2
1
2
α
α
α
α
α
α
α
α
α
α
π
ν
σ r
h
KN
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 22
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.4. Compton scattering by free electrons
σs : Scattering coefficient
σtr : Energy transfer coefficient
σKN : Total cross section for Compton scattering
σtr can be obtained integrating over all angles with
tr
KN
s
σ
σ
σ −
=
In the incoherent free electron scattering process the initial
photon energy is divided between the scattered photon and the
recoiling electron. The differential energy transfer coefficient is
given by:
( ) ( )
( )







−
+
−
+
=
Ω θ
α
θ
α
θ
σ
cos
1
1
cos
1
cos
1
2
d
d 2
2
0
KN
tr
f
r
θ
θ
π d
sin
2
d =
Ω
The scattering coefficient is, then, by definition:
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 23
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.5. Incoherent scattering
For incoherent scattering by bound atomic electrons, the
contributions from individual electrons are added and the
differential cross section takes the form:
S is known as the incoherent
scattering function, and is a universal
function of the momentum transfer
quantity x and the atomic number. S is
zero in the forward direction and
increases with increasing momentum
transfer reaching the value of Z, the
number of electrons per atom. This
increase becomes slower as the
atomic number increases
0.01 0.1 1 10
0.00
0.25
0.50
0.75
1.00
C
Fe
Pt
x (Å-1
)
Normalized
incoherent
scattering
function
(S/Z)
Data from Hubbell, Veigele et al., J Phys Chem
Ref Data 4(3) (1975)
( ) ( )
Z
x
S
f
r
KN
incoh
,
cos
1
2
d
d 2
2
0
θ
σ
+
=
Ω
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 24
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.5. Incoherent scattering
In many situations it is very nearly equal to
the single electron cross section multiplied
by the number of electrons in the atom
The total cross section for incoherent scattering
is obtained by numerical integration of equation:
( ) ( )
Z
x
S
f
r
KN
incoh
,
cos
1
2
d
d 2
2
0
θ
σ
+
=
Ω
KN
incoh Zσ
σ ≈
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 25
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.6. Pair and Triplet production
As pair production occurs in the field of
the nucleus, the cross-section for this
interaction varies approximately as Z²
where Z is the nuclear charge
Pair
production
incident photon
hν
p = hν /c
e-
T-
e+
T+
Tatom
Pair production cannot take place for photons
with energies less than the energy threshold
2 m0c2 = 1022 keV
When a high energy photon passes near to an atomic
nucleus, the photon may interact with the nuclear
Coulomb field by a process called pair production
The photon is converted into an electron-positron
pair, each with its own kinetic energy. The energy
balance is: 2
0
2 c
m
T
T
h +
+
= −
+
ν
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 26
Triplet
production
2.2. INTERACTIONS OF PHOTONS WITH MATTER
2.2.6. Pair and Triplet production
Thresholds for pair and triplet production are
much higher than the photon energies
relevant to diagnostic radiology
When a high energy photon passes near to an orbital
electron, the photon may interact with the Coulomb
field of this electron by a process called triplet
production
The energy threshold for Triplet production is 4 m0c2
The target electron is itself ejected with considerable
energy. Two electrons and one positron are thus set
into motion
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 27
2.3. PHOTON ATTENUATION COEFFICIENTS
The exit beam from the bulk material will also comprise both
primary and scattered photons. Such effects are best estimated
using Monte Carlo techniques
Photons may undergo more than one interaction as they
pass through bulk material:
An initial scatter interaction might be followed by a
second scattering process which in turn might be followed by a
third scatter, photoelectric absorption or no further interactions
with the photon leaving the bulk material, for example
To consider this macroscopic behaviour of primary photons
traversing matter
• linear attenuation coefficients and
• mass attenuation coefficients
are used, which are simply related to the total cross section
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 28
2.3. PHOTON ATTENUATION COEFFICIENTS
2.3.1. Linear attenuation coefficient
Consider a thin uniform slab of material of thickness
dx, which is irradiated with a beam of photons incident
normally on the slab
dx
Individual photons may pass through the slab without
interacting, or they may be absorbed or scattered
Na is the number of interaction centres (atoms) per unit volume
σ is the total interaction cross section per atom
For scattering by atoms, Na may be calculated from the Avogadro
constant NA, the atomic weight Ar and the density ρ
Linear attenuation coefficient: (S.I.)
σ
ρ
µ
σ
r
A
a
A
N
N
1000
)
m
( 1
=
= −
The probability that an individual photon will interact
in this thin section is given by: x
Na d
σ
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 29
2.3. PHOTON ATTENUATION COEFFICIENTS
2.3.2. Exponential attenuation
A radiation field at a point P can be
quantified by the physical non-
stochastic quantity fluence, which
is usually expressed in units of m-2
or cm-2, and is given by:
where dN is the differential of the expectation value of the number of
particles (photons, or massive particles) striking an infinitesimal
sphere with a great-circle area da surrounding point P
Definition of fluence Φ
a
N
d
d
Φ =
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 30
2.3. PHOTON ATTENUATION COEFFICIENTS
2.3.2. Exponential attenuation
Now consider a thick slab of material. Φ(x) represents the
fluence of photons which have not interacted in the slab
after passage through thickness x. The expected change dΦ
in this fluence after passage through a further thickness dx
is given by:
This equation, known as Beer’s law,
describes the exponential attenuation of a
photon beam
Integrating:
x
d
d µ
Φ
−
=
Φ
x
e
µ
−
Φ
=
Φ 0
is the initial fluence
Φ0
Φ0
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 31
2.3. PHOTON ATTENUATION COEFFICIENTS
2.3.2. Exponential attenuation
It should be noted that it describes the
number of photons which have not
interacted, also known as primary photons
At diagnostic energies other photons may
be present at depth resulting from photon
scattering interactions or the emission of
fluorescent photons following a
photoelectric interaction
Beer’s law, describes the
exponential attenuation of a photon
beam
x
e
µ
−
Φ
=
Φ 0
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 32
2.3. PHOTON ATTENUATION COEFFICIENTS
2.3.3. Mass attenuation coefficient
The linear attenuation coefficient µ (m-1) is
dependent on density which in turn is
dependent on the physical state of the material
As a consequence µ is not a suitable quantity
for data compilations
Physical state Energy of photon (keV) µ (m-1) µ /ρ (m2/kg)
water 50 21.4 0.0226
ice 50 19.6 0.0226
The quantity mass attenuation coefficient
is independent of density








kg
m2
ρ
µ
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 33
2.3. PHOTON ATTENUATION COEFFICIENTS
2.3.4. Mass energy transfer coefficients and
mass energy absorption coefficients
For dosimetric purposes it is necessary to know the energy
transferred to secondary electrons as a result of the initial interaction
µ linear attenuation coeficcient
µ tr linear transfer coefficient
µtr /ρ mass energy transfer coefficient
µen /ρ mass energy absorption coefficient
K = d (hν)tr/dm Kerma
<T> is the expectation value of the energy converted to
secondary electrons
hν is the energy of photon
ν
µ
µ
h
T
tr =
energy d(hν)tr transferred by interactions to
kinetic energy of electrons when photons of
energy hν traverse a distance dx in a material
( ) x
h
h tr
tr d
d µ
ν
ν Φ
=
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 34
Some of the energy transferred to the secondary charged particles is
lost to radiative processes in the material, mainly Bremsstrahlung
2.3. PHOTON ATTENUATION COEFFICIENTS
2.3.4. Mass energy transfer coefficients and
mass energy absorption coefficients
g gives the energy fraction lost to radiative processes. For the
energies used in diagnostic radiology, g may be taken as zero
This is taken account by
the mass energy
absorption coefficient:
( )
g
tr
en
−








=








1
ρ
µ
ρ
µ
K (Kerma): energy
transferred from uncharged
particles to matter
dm = ρ dx
( )








Φ
=
Φ
=
=
ρ
µ
ν
µ
ν
ν tr
tr
tr
h
m
x
h
m
h
K
d
d
d
d
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 35
2.3. PHOTON ATTENUATION COEFFICIENTS
2.3.5. Contribution of individual interactions to the
total mass attenuation coefficient
The four distinctly different mechanisms by which
photons may interact with matter compete, according
to their individual probabilities. The total mass
attenuation coefficient is therefore the sum of all the
individual mass attenuation coefficients:
The size of each attenuation coefficient will depend
on the photon energy and the atomic number of the
material
( ) 1000
r
A
inc
coh
inc
coh
A
N
κ
σ
σ
τ
ρ
κ
ρ
µ
ρ
µ
ρ
τ
ρ
µ
+
+
+
=








+








+








+








=








IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 36
2.3. PHOTON ATTENUATION COEFFICIENTS
2.3.5. Contribution of individual interactions to the
total mass attenuation coefficient
Mass attenuation coefficients for water for
photon energies from 1 keV to 300 keV
1 10 100
10- 3
10- 2
10- 1
100
101
102
103
104
Photon energy (keV)
cm
/g
coherent
incoherent
photoelectric
total
Mass
attenuation
coefficient
(cm
2
/g)
The photoelectric interaction
makes the dominant contribution
to the total interaction cross
section at the lowest energies. The
steep decrease at the lower photon
energies is characteristic for the
photoelectric effect and ends when
incoherent (Compton) scattering
becomes dominant and remains so
for the rest of the diagnostic
energy range. The cross-over
position for these two interactions
depends on the atomic number
For water is about 30 keV
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 37
2.3. PHOTON ATTENUATION COEFFICIENTS
2.3.5. Contribution of individual interactions to the
total mass attenuation coefficient
1 10 100
10- 2
100
102
104
Photon Energy (keV)
Mass
attenuation
coefficient
(cm
2
/g)
iodine
gadox
lead
adipose In the energy range up to
100 keV and for the high Z
materials, the discontinuities
arising from the differences in
photoelectric absorption at K,
L and M edges are evident
Total mass interaction coefficients for
materials relevant to diagnostic
radiology (adipose tissue, iodine,
gadolinium oxysulphide (gadox) and
lead
The differences in absorption
that this creates are important
for the design of filters used to
shape X-ray spectra
(particularly in mammography
and for imaging using iodinated
contrast agents)
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 38
2.3. PHOTON ATTENUATION COEFFICIENTS
2.3.6. Coefficients for compounds and mixtures
Mass attenuation coefficients and mass energy-transfer
coefficients for compounds and intimate mixtures can be
obtained by a weighted summation of the coefficients of the
constituents:
wi are the normalized weight fractions of
the elements i (or mixture components i)
present in the absorber
The mass energy-absorption coefficient for
an element accounts for the radiative
losses of the secondary electrons
i
i i
w
∑ 







=








ρ
µ
ρ
µ
i
i i
tr
tr
w
∑ 







=








ρ
µ
ρ
µ
i
i i
en
en
w
∑ 







=








ρ
µ
ρ
µ
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 39
2.4. INTERACTIONS OF ELECTRONS WITH MATTER
Energy loss by electrons
Ionizational or collisional losses Radiative losses or Bremsstrahlung
Principal process:
collisions with other electrons
Energy losses and the changes
in direction can be quite large
The electron which leaves the
collision with the most energy is
assumed to be the original
incident electron. This means the
maximum energy exchange is
half of the original energy
Interaction with the electric field
of nuclei and be decelerated so
rapidly that some of its energy
may be radiated away
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 40
Energy lost by charged
particles in passing
through matter is
generally described using
a quantity called stopping
power S
2.4. INTERACTIONS OF ELECTRONS WITH MATTER
dT is the loss in kinetic energy
of the particle as it travels a
distance dx. ρ is the density of
the material
Stopping power
Mass stopping power
x
T
S
d
d
=
x
T
S
d
d
1
ρ
ρ
=
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 41
2.4. INTERACTIONS OF ELECTRONS WITH MATTER
2.4.1. Ionizational (Collisional) Interactions and
Ionizational Stopping Power
This process involves collisions
between electrons travelling through
matter and electrons from atoms that
are part of the material, leaving the
atoms ionized
It is rather difficult to measure the rate of energy
lost by these interactions but is relatively easy to
calculate it. Relativity and Quantum Mechanics
must be used
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 42
The problem was first solved by Bethe in the early part of the 20th
century. The Ionizational Mass Stopping Power (Sion/ρ) (MeV⋅cm2 ⋅g-1)
was derived by Bethe-Bloch and extended by Sternheimer:
( ) ( )
( ) 







−
−
+
+
+
−
+
+
= δ
β
µ
µ
µ
µ
µ
β
µ
π
ρ
2
2
0
0
0
2
2
0
0
2
2
0
2
0 1
2
ln
2
8
/
2
2
ln
2
T
T
T
I
T
T
N
r
S
e
ion
r0 is the “classical radius of the electron”
Ne = NA(Z/Ar), NA is the Avogadro constant
µ0 = m0c2 is the rest mass of the electron multiplied by the speed of light squared
T is the kinetic energy
β is the ratio of the speed of the electron to that of light
The density correction term δ, was added later by Sternheimer. Its effect is to reduce energy
losses, but only at high energies. At 100 MeV it can be as great as 20%
I is a semi-empirical quantity called the “Mean Excitation Energy” which is a property of the
material and increases as the atomic number of the material increases. Values of I for a large
number of materials are given by NIST
2.4. INTERACTIONS OF ELECTRONS WITH MATTER
2.4.1. Ionizational (Collisional) Interactions and
Ionizational Stopping Power
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 43
( ) ( )
( ) 







−
−
+
+
+
−
+
+
= δ
β
µ
µ
µ
µ
µ
β
µ
π
ρ
2
2
0
0
0
2
2
0
0
2
2
0
2
0 1
2
ln
2
8
/
2
2
ln
2
T
T
T
I
T
T
N
r
S
e
ion
Below 100 keV or so, the term 2π r0
2Ne µ0/β 2 is the most important
The factor 1/β 2 = c2/v2 makes the stopping power nearly inversely
proportional to the kinetic energy
For energies above 100 keV β is essentially 1 and the term in front
becomes nearly constant
The terms inside the square bracket increase slowly with energy
and the stopping power passes through a minimum in the
neighborhood of 1 MeV
2.4. INTERACTIONS OF ELECTRONS WITH MATTER
2.4.1. Ionizational (Collisional) Interactions and
Ionizational Stopping Power
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 44
( ) ( )
( ) 







−
−
+
+
+
−
+
+
= δ
β
µ
µ
µ
µ
µ
β
µ
π
ρ
2
2
0
0
0
2
2
0
0
2
2
0
2
0 1
2
ln
2
8
/
2
2
ln
2
T
T
T
I
T
T
N
r
S
e
ion
Dependence on atomic number is not strong
The factor in front of the square brackets contains the number of
electrons per unit mass, given by NA(Z/Ar), and remembering Z/Ar is
0.5 or slightly less, for all materials except hydrogen, the mass
stopping power decreases only slightly as atomic number increases
The mean excitation energy, I, increases as atomic number
increases, which also serves to make Sion smaller for high atomic
number materials
2.4. INTERACTIONS OF ELECTRONS WITH MATTER
2.4.1. Ionizational (Collisional) Interactions and
Ionizational Stopping Power
IAEA
The function B = B(hν/T) is a slowly
varying function of T and Z with an
average for non-relativistic energies,
T << m0c2, of 3
/
16
=
B
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 45
2.4. INTERACTIONS OF ELECTRONS WITH MATTER
2.4.2. Radiative Interactions and Radiative Stopping Power
When an electron passes close to a nucleus it will experience a
substantial Coulomb force and will be decelerated, radiating
energy in the form of electromagnetic radiation (Bremsstrahlung)
The quantum mechanical solution is complicated and
approximations must be made, and the most appropriate form for
the result depends on the energy range
The energy loss due to this process is
quite strongly dependent on the
atomic number, as can be seen by the
Z2 term
The approximate Radiative Mass
Stopping Power (Srad/ρ )(MeV·cm2 ·g-1)
for diagnostic energies is:
= 0.580 barn/nucleus
( )B
T
Z
A
N
S
r
A
rad
0
2
0
µ
σ
ρ
+
=
2
0
2
0
137
1








=
µ
σ e
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 46
2.4. INTERACTIONS OF ELECTRONS WITH MATTER
2.4.3. Total Stopping Power
The total stopping power is the sum of the
ionizational and radiative stopping powers:
Ionizational, radiative and total stopping powers for water
and tungsten for electron energies from 10 keV to 10 MeV
10 100 1000 10000
10- 3
10- 2
10- 1
100
101
102
Ionizational
Radiative
Total
water
Stopping
power
(MeV
⋅
cm
2
⋅g
-1
)
Energy (keV)
10 100 1000 10000
10- 2
10- 1
100
101
Ionizational
Radiative
Total
tungsten
Stopping
power
(MeV
⋅
cm
2
⋅g
-1
)
Energy (keV)
rad
ion
tot S
S
S +
=
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 47
2.4. INTERACTIONS OF ELECTRONS WITH MATTER
2.4.4. Stopping power in Compounds and Mixtures
The mass stopping power can be approximated for
compounds or intimate mixtures by a weighed
addition of the mass stopping power of the elemental
constituents assuming independent contribution to
stopping power:
wi are the normalized weight fractions of the elements i
present in the material. The influence of chemical
binding is neglected here
i
i i
w
S
S
∑ 







=








ρ
ρ
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 48
2.4. INTERACTIONS OF ELECTRONS WITH MATTER
2.4.5. Linear Energy Transfer
The mass collision stopping power characterizes the energy loss of
the electron due to all collisions. The secondary electrons resulting
from hard collisions (δ-rays) carry part of the energy some distance
away from the track and may escape the volume of interest
In radiobiology, the use of the collision stopping power can result in an
overestimation of dose. In such situations, the restricted stopping power
may be used which relates to the energy lost in the absorber by secondary
particles not exceeding an energy limit ∆ (typically 10 keV), thus limiting
the volume of interest to the range of electrons with energy ∆
The restricted stopping power may be expressed as mass restricted
stopping power (S/ρ)Res or, for a description of the energy passed to the
medium per unit track length, it is common to use the linear energy
transfer L∆ :
Linear energy transfer L∆ (keV/µm):
∆
∆ 







=
x
T
L
d
d
1
10 ρ
ρ
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 49
2.5. DATA SOURCES
Data for photon attenuation coefficients and
stopping powers can be found in many
textbooks but are conveniently obtained from
web based data sources provided by:
• NIST (Berger, Hubbell et al., 2005;
Berger, Coursey, et al, 2005)
or from the tabulations in:
• ICRU (1992)
The composition of body tissues and
phantom materials are given in:
• ICRU (1989) and
• ICRP (2003)
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 50
• BERGER, M.J., ESTAR, PSTAR AND ASTAR: Computer
Programs for Calculating Stopping-Power and Ranges for
Electrons, Protons and Helium Ions. NIST Report NISTIR-4999
(1992)
• BERGER, M.J., COURSEY, J.S., ZUCKER, M.A. AND CHANG, J.,
ESTAR, PSTAR, and ASTAR: Computer Programs for Calculating
Stopping-Power and Range Tables for Electrons, Protons and
Helium Ions (version 1.2.3), NIST, Gaithersburg, MD (2005)
Available: http://physics.nist.gov/Star [2008, February 7]
• BERGER, M.J., HUBBELL, J.H., SELTZER, S.M., CHANG, J.,
COURSEY, J.S., SUKUMAR, R., and ZUCKER, D.S. (2005), XCOM:
Photon Cross Section Database (version 1.3). Available:
http://physics.nist.gov/xcom [2008, March 20]. NIST,
Gaithersburg, MD
BIBLIOGRAPHY
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 51
BIBLIOGRAPHY
• HUBBELL, J.H., Review of Photon Interaction Cross Section
Data in the Medical and Biological Context, Phys. Med. Biol. 44
R1-22 (1999)
• INTERNATIONAL COMMISSION ON RADIATION UNITS AND
MEASUREMENTS, Stopping Powers for Electrons and
Positrons, Rep. 37, ICRU, Bethesda, MD (1984)
• INTERNATIONAL COMMISSION ON RADIATION UNITS AND
MEASUREMENTS, Tissue Substitutes in Radiation Dosimetry
and Measurement, Rep. 44, ICRU, Bethesda, MD (1989)
• INTERNATIONAL COMMISSION ON RADIATION UNITS AND
MEASUREMENTS, Photon, Electron, Proton and Neutron
Interaction Data for Body Tissues, Rep. 46, ICRU, Bethesda,
MD (1992)
IAEA
Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 52
BIBLIOGRAPHY
• INTERNATIONAL COMMISSION ON RADIOLOGICAL
PROTECTION, Basic Anatomical and Physiological Data for use
in Radiological Protection: Reference Values ICRP Rep. 85,
Pergamon Press, Oxford, (2003)
• JOHNS, H.E. and CUNNINGHAM J.R. The Physics of Radiology
(Fourth Edition), Charles C Thomas, Springfield, Illinois (1983)
• NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY
(NIST), 100 Bureau Drive, Stop 1070, Gaithersburg, MD 20899-
1070. Available: http://www.nist.gov/index.html
• SELTZER, S.M., BERGER, M.J., Evaluation of the Collision
Stopping Power of Elements and Compounds for Electrons and
Positrons, Int J Appl Radiat Isot 33, 1189-1218 (1982)

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Chapter_02.pdf

  • 1. IAEA International Atomic Energy Agency Slide set of 52 slides based on the chapter authored by J. R. Cunningham and D. R. Dance of the IAEA publication (ISBN 978-92-0-131010-1): Diagnostic Radiology Physics: A Handbook for Teachers and Students Objective: To familiarize students with the physics of events that occur when photons and electrons interact with matter Chapter 2: Interactions of Radiation with Matter Slide set prepared by E.Okuno (S. Paulo, Brazil, Institute of Physics of S. Paulo University)
  • 2. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 2 Chapter 2. TABLE OF CONTENTS 2.1. Introduction 2.2. Interactions of photons with matter 2.3. Photon attenuation coefficients 2.4. Interactions of electrons with matter 2.5. Data sources
  • 3. IAEA 2.1. INTRODUCTION This chapter deals with the physics of events that occur when photons and electrons interact with matter. These are the radiations that are important for diagnostic radiology, and only those interactions which result in their attenuation, absorption and scattering are dealt with The energy range used for diagnostic radiology is generally on the boundary between classical and quantum physics and following the “Complementarity Principle”, the numerical details of the interactions will be treated by classical reasoning where that is appropriate and by quantum mechanical considerations where that gives superior results Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 3
  • 4. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 4 The interaction of photons and electrons, as they traverse matter, are stochastic and obey the laws of chance, although, with very different behaviour: • Electrons experience large numbers of interactions and in general gradually lose energy until they are stopped. This is expressed in terms of electron range and material stopping powers • Photons in general have none, one or a few interactions and are exponentially attenuated Photon interactions are expressed in terms of cross-sections for individual interactions and attenuation coefficients for passage through bulk media 2.1. INTRODUCTION
  • 5. IAEA If there are Φ photons randomly directed at area A, that contains n targets, each with area σ, the expected number of interactions ∆Φ between photons and targets will be ( ) A n σ Φ = ∆Φ Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 5 2.2. INTERACTIONS OF PHOTONS WITH MATTER The probability of a single photon incident on a slab of material of area A, that contains one target of cross-sectional area σ, interacting with the target will be the ratio of the two areas: σ/A Another way of saying this is that the probability of a projectile making a hit is n (σ/A), which is just the fraction of the area that is blocked off by the targets
  • 6. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 6 2.2. INTERACTIONS OF PHOTONS WITH MATTER Changing now the targets to: atoms, their cross-section would be an atomic cross-section This wouldn’t be an actual area of the atom, but would be an effective area – effective for an interaction between the photon and the atom that is being considered Cross-sections are frequently represented by the symbol σ and conventionally expressed in a unit of area called the barn (b) 1 barn = 10-28 m2
  • 7. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 7 2.2. INTERACTIONS OF PHOTONS WITH MATTER There are four fundamental X-ray interactions that we need to consider; each can be associated with a specific cross-section The first three of these interactions are important in the diagnostic energy range up to 150 keV Pair and triplet production are only important at much higher energies and are only treated here for completeness Interaction Cross-section photoelectric effect τ coherent scattering σcoh incoherent scattering σincoh pair and triplet production κ
  • 8. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 8 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.1. Photoelectric Effect K L M N before collision hν In the photoelectric effect the incident photon interacts with an atom and disappears. A photoelectron is ejected The photoelectric effect can only take place if the photon energy hν > Es (binding energy) K L M N after collision photoelectron T = hν - Es The most probable electron shell to lose an electron is the one that satisfies this constraint and has the highest binding energy
  • 9. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 9 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.1. Photoelectric Effect Calculation of the probability of the interaction is very complicated and quantum mechanics is required In the diagnostic energy range up to 150 keV, the photoelectric effect cross-section per atom, τ, is approximately given by: k is a constant Z is the atomic number n is an exponent in the range 3.6-5.3, being largest for low atomic numbers m is an exponent in the range 2.5-3.5, again being largest for low atomic numbers A typical dependence of τ in the diagnostic photon energy range is: ( )3 4 hv Z ∝ τ ( ) ( )m n hv Z k Z h = , ν τ
  • 10. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 10 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.1. Photoelectric Effect Atomic photoelectric cross sections for copper, molybdenum and tungsten For tungsten, the discontinuity seen at 69.5 keV represents the effect of the K shell. At an energy just less than this, the cross section is 6.4 x 102 b/atom, while just above this energy, the coefficient is 3.3 x 103 b/atom. This represents a sudden increase in cross-section of about a factor of five when the photon energy increases above that of the K shell (K-edge) Thus the major contribution to the cross-section above the K-edge comes from interactions with the two K-shell electrons The sharp discontinuities correspond to the positions of the absorption edges for the different materials, which increase in energy with increasing atomic number and shell binding energy W K-edge 1 10 100 100 102 104 106 108 Cu W Mo Photon Energy (keV) τ (b/atom)
  • 11. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 11 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.2. Thomson Scattering dΩ θ dV Incident photon Scattered photon A photon incident on a small volume element dV is scattered through angle θ into the solid angle element dΩ is the differential cross section J.J. Thomson gave the first treatment of the scattering of photons by electrons in the very early years of the 20th century The probability that the photon will interact and be scattered into solid angle dΩ is proportional to: Ω Ω d d dσ Ω d dσ The total cross section is obtained by integrating over all solid angles: ∫ Ω Ω = d d dσ σ
  • 12. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 12 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.2. Thomson Scattering Thomson’s derivation of the scattering of a photon by a single free electron at rest is based on classical physics and results in a description that is only meaningful at the low energy limit of this interaction r0 is “classical radius of the electron” k is a proportionality constant from Coulomb’s law e is the charge on the electron m0 is the rest mass of the electron c is the speed of light m 10 81794 . 2 15 2 0 2 0 − × = = c m e k r Thomson showed that the differential cross section, at scattering angle θ, is given by : ( ) θ σ 2 2 0 cos 1 2 d d + = Ω r Th
  • 13. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 13 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.2. Thomson Scattering This equation predicts that the same amount of energy will be scattered forward as backward, and also that the energy scattered at right angles will be half this amount. Except at low energies, this result does not agree with observation or with the predictions made by quantum mechanics Total cross-section Differential cross-section σTh is constant, predicting that the classical scattering probability is independent of electromagnetic radiation energy This, of course, is not correct ( ) θ σ 2 2 0 cos 1 2 d d + = Ω r Th ( ) 2 30 2 0 0 2 2 0 m 10 x 52 . 66 3 8 d sin cos 1 2 2 − = = + = ∫ r r Th π θ θ θ π σ π
  • 14. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 14 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.3. Coherent (Rayleigh) Scattering In reality the photon is scattered collectively by the atomic electrons which are not free, and their proximity to one another is not very different from the wavelength of the radiation In deriving the expression for Thomson scattering it was assumed that the electron was free, alone and at rest In coherent scattering essentially no energy is lost by the photon as it transfers momentum to the atom and is scattered through angle θ The scattering by the different electrons is in phase and the resultant angular distribution is determined by an interference pattern which is characteristic of the atom
  • 15. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 15 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.3. Coherent (Rayleigh) Scattering The differential cross section is then given by: is the Thomson differential scattering coefficient and F is known as the coherent form factor It may be calculated using quantum mechanical models λ is the wavelength of the incident photon. The parameter x is proportional to the transfer of momentum between the initial and scattered photon directions ( ) Z x F Th coh , d d d d 2 Ω = Ω σ σ d Ω d Th σ ( ) λ θ 2 sin = x
  • 16. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 16 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.3. Coherent (Rayleigh) Scattering Variation of the normalized form factor F/Z for coherent scattering with the momentum transfer parameter x Data from Hubbell and Øverbø, J Phys Chem Ref Data 8, 69-106 (1979) 0.01 0.1 1 10 0.00 0.25 0.50 0.75 1.00 C Fe Pt x (Å-1 ) Normalized form factor (F/Z) For scattering in the forward direction all the atomic electrons act together, and F is equal to the atomic number and the differential cross section depends upon Z2 However, for a given value of the scattering angle, the normalized coherent form factor F/Z, increases with increasing atomic number As the scattering angle increases, F decreases because it becomes increasingly difficult for all the electrons to scatter in phase without any energy transfer
  • 17. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 17 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.4. Compton scattering by free electrons Compton Scattering, like Thomson scattering, is the interaction between electromagnetic radiation and a free electron, but in this case there is an energy transfer to the electron Both the photon and the electron must be considered as particles The energy range is such that relativity and quantum mechanics must be used to derive expressions for the cross section
  • 18. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 18 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.4. Compton scattering by free electrons θ ϕ scattered photon hν’ p’ = hν’/c incident photon hν p = hν /c recoil electron Te pe Using conservation of energy and momentum Compton relations can be derived: ( ) θ α ν ν cos 1 1 1 − + = ′ h h 2 0c m h α ν = ( )       + = 2 tan 1 cot θ α ϕ ( ) ( ) θ α θ α ν ν cos 1 1 cos 1 − + − = ′ − = hv h h Te
  • 19. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 19 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.4. Compton scattering by free electrons 10 10 20 20 50 50 100 100 Incident photon energy (keV) Scattered photon energy (keV) ( ) θ α ν ν cos 1 1 1 − + = ′ h h ( ) ( ) θ α θ α ν ν cos 1 1 cos 1 − + − = ′ − = hv h h Te In the diagnostic energy range is small, and as a consequence the energy transfer to the recoil electron is also small, being zero in the forward direction and taking its largest value when the photon is backscattered 2 0c m h α ν = For 20 keV, 50 keV and 100 keV incident photons, the maximum energy transfers to the recoil electron are: 1.5 keV, 8.2 keV and 28.1 keV respectively
  • 20. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 20 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.4. Compton scattering by free electrons The cross-section for the scattering of a photon, with energy hν through a given angle θ, was first derived in 1928 by Klein and Nishina using the Dirac theory of the electron This cross-section reduces to the Thomson cross-section when α → 0 (that is hν’/ hν → 1) 0 50 100 150 0.0 0.1 0.2 0.3 0.0 0.1 0.2 0.3 dσ/dΩ dσ/dθ Scattering angle (degrees) Photon scattering angle (degree) Compton differential cross-sections for scattering of 70 keV photons (b/rad) (b/sr) The expression for the differential cross-section for scattering of photons by a single free electron is: ( )       + − + − +       − + = ] cos 1 )][ cos 1 ( 1 [ cos 1 1 ) cos 1 ( 1 1 2 2 2 2 θ θ α θ α θ α KN f ( ) KN KN f r θ σ 2 2 0 cos 1 2 d d + = Ω
  • 21. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 21 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.4. Compton scattering by free electrons The total Compton cross-section (probability of interaction per electron) for a photon of energy hν, is obtained by integrating the differential cross section over solid angle. The result is: ( ) KN KN f r θ σ 2 2 0 cos 1 2 d d + = Ω ( ) ( ) ( ) ( ) ( )       + + − + +         + − + +       + = 2 2 2 0 2 1 3 1 2 2 1 ln 2 1 ln 2 1 1 2 1 2 α α α α α α α α α α π ν σ r h KN
  • 22. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 22 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.4. Compton scattering by free electrons σs : Scattering coefficient σtr : Energy transfer coefficient σKN : Total cross section for Compton scattering σtr can be obtained integrating over all angles with tr KN s σ σ σ − = In the incoherent free electron scattering process the initial photon energy is divided between the scattered photon and the recoiling electron. The differential energy transfer coefficient is given by: ( ) ( ) ( )        − + − + = Ω θ α θ α θ σ cos 1 1 cos 1 cos 1 2 d d 2 2 0 KN tr f r θ θ π d sin 2 d = Ω The scattering coefficient is, then, by definition:
  • 23. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 23 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.5. Incoherent scattering For incoherent scattering by bound atomic electrons, the contributions from individual electrons are added and the differential cross section takes the form: S is known as the incoherent scattering function, and is a universal function of the momentum transfer quantity x and the atomic number. S is zero in the forward direction and increases with increasing momentum transfer reaching the value of Z, the number of electrons per atom. This increase becomes slower as the atomic number increases 0.01 0.1 1 10 0.00 0.25 0.50 0.75 1.00 C Fe Pt x (Å-1 ) Normalized incoherent scattering function (S/Z) Data from Hubbell, Veigele et al., J Phys Chem Ref Data 4(3) (1975) ( ) ( ) Z x S f r KN incoh , cos 1 2 d d 2 2 0 θ σ + = Ω
  • 24. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 24 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.5. Incoherent scattering In many situations it is very nearly equal to the single electron cross section multiplied by the number of electrons in the atom The total cross section for incoherent scattering is obtained by numerical integration of equation: ( ) ( ) Z x S f r KN incoh , cos 1 2 d d 2 2 0 θ σ + = Ω KN incoh Zσ σ ≈
  • 25. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 25 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.6. Pair and Triplet production As pair production occurs in the field of the nucleus, the cross-section for this interaction varies approximately as Z² where Z is the nuclear charge Pair production incident photon hν p = hν /c e- T- e+ T+ Tatom Pair production cannot take place for photons with energies less than the energy threshold 2 m0c2 = 1022 keV When a high energy photon passes near to an atomic nucleus, the photon may interact with the nuclear Coulomb field by a process called pair production The photon is converted into an electron-positron pair, each with its own kinetic energy. The energy balance is: 2 0 2 c m T T h + + = − + ν
  • 26. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 26 Triplet production 2.2. INTERACTIONS OF PHOTONS WITH MATTER 2.2.6. Pair and Triplet production Thresholds for pair and triplet production are much higher than the photon energies relevant to diagnostic radiology When a high energy photon passes near to an orbital electron, the photon may interact with the Coulomb field of this electron by a process called triplet production The energy threshold for Triplet production is 4 m0c2 The target electron is itself ejected with considerable energy. Two electrons and one positron are thus set into motion
  • 27. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 27 2.3. PHOTON ATTENUATION COEFFICIENTS The exit beam from the bulk material will also comprise both primary and scattered photons. Such effects are best estimated using Monte Carlo techniques Photons may undergo more than one interaction as they pass through bulk material: An initial scatter interaction might be followed by a second scattering process which in turn might be followed by a third scatter, photoelectric absorption or no further interactions with the photon leaving the bulk material, for example To consider this macroscopic behaviour of primary photons traversing matter • linear attenuation coefficients and • mass attenuation coefficients are used, which are simply related to the total cross section
  • 28. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 28 2.3. PHOTON ATTENUATION COEFFICIENTS 2.3.1. Linear attenuation coefficient Consider a thin uniform slab of material of thickness dx, which is irradiated with a beam of photons incident normally on the slab dx Individual photons may pass through the slab without interacting, or they may be absorbed or scattered Na is the number of interaction centres (atoms) per unit volume σ is the total interaction cross section per atom For scattering by atoms, Na may be calculated from the Avogadro constant NA, the atomic weight Ar and the density ρ Linear attenuation coefficient: (S.I.) σ ρ µ σ r A a A N N 1000 ) m ( 1 = = − The probability that an individual photon will interact in this thin section is given by: x Na d σ
  • 29. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 29 2.3. PHOTON ATTENUATION COEFFICIENTS 2.3.2. Exponential attenuation A radiation field at a point P can be quantified by the physical non- stochastic quantity fluence, which is usually expressed in units of m-2 or cm-2, and is given by: where dN is the differential of the expectation value of the number of particles (photons, or massive particles) striking an infinitesimal sphere with a great-circle area da surrounding point P Definition of fluence Φ a N d d Φ =
  • 30. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 30 2.3. PHOTON ATTENUATION COEFFICIENTS 2.3.2. Exponential attenuation Now consider a thick slab of material. Φ(x) represents the fluence of photons which have not interacted in the slab after passage through thickness x. The expected change dΦ in this fluence after passage through a further thickness dx is given by: This equation, known as Beer’s law, describes the exponential attenuation of a photon beam Integrating: x d d µ Φ − = Φ x e µ − Φ = Φ 0 is the initial fluence Φ0 Φ0
  • 31. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 31 2.3. PHOTON ATTENUATION COEFFICIENTS 2.3.2. Exponential attenuation It should be noted that it describes the number of photons which have not interacted, also known as primary photons At diagnostic energies other photons may be present at depth resulting from photon scattering interactions or the emission of fluorescent photons following a photoelectric interaction Beer’s law, describes the exponential attenuation of a photon beam x e µ − Φ = Φ 0
  • 32. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 32 2.3. PHOTON ATTENUATION COEFFICIENTS 2.3.3. Mass attenuation coefficient The linear attenuation coefficient µ (m-1) is dependent on density which in turn is dependent on the physical state of the material As a consequence µ is not a suitable quantity for data compilations Physical state Energy of photon (keV) µ (m-1) µ /ρ (m2/kg) water 50 21.4 0.0226 ice 50 19.6 0.0226 The quantity mass attenuation coefficient is independent of density         kg m2 ρ µ
  • 33. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 33 2.3. PHOTON ATTENUATION COEFFICIENTS 2.3.4. Mass energy transfer coefficients and mass energy absorption coefficients For dosimetric purposes it is necessary to know the energy transferred to secondary electrons as a result of the initial interaction µ linear attenuation coeficcient µ tr linear transfer coefficient µtr /ρ mass energy transfer coefficient µen /ρ mass energy absorption coefficient K = d (hν)tr/dm Kerma <T> is the expectation value of the energy converted to secondary electrons hν is the energy of photon ν µ µ h T tr = energy d(hν)tr transferred by interactions to kinetic energy of electrons when photons of energy hν traverse a distance dx in a material ( ) x h h tr tr d d µ ν ν Φ =
  • 34. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 34 Some of the energy transferred to the secondary charged particles is lost to radiative processes in the material, mainly Bremsstrahlung 2.3. PHOTON ATTENUATION COEFFICIENTS 2.3.4. Mass energy transfer coefficients and mass energy absorption coefficients g gives the energy fraction lost to radiative processes. For the energies used in diagnostic radiology, g may be taken as zero This is taken account by the mass energy absorption coefficient: ( ) g tr en −         =         1 ρ µ ρ µ K (Kerma): energy transferred from uncharged particles to matter dm = ρ dx ( )         Φ = Φ = = ρ µ ν µ ν ν tr tr tr h m x h m h K d d d d
  • 35. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 35 2.3. PHOTON ATTENUATION COEFFICIENTS 2.3.5. Contribution of individual interactions to the total mass attenuation coefficient The four distinctly different mechanisms by which photons may interact with matter compete, according to their individual probabilities. The total mass attenuation coefficient is therefore the sum of all the individual mass attenuation coefficients: The size of each attenuation coefficient will depend on the photon energy and the atomic number of the material ( ) 1000 r A inc coh inc coh A N κ σ σ τ ρ κ ρ µ ρ µ ρ τ ρ µ + + + =         +         +         +         =        
  • 36. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 36 2.3. PHOTON ATTENUATION COEFFICIENTS 2.3.5. Contribution of individual interactions to the total mass attenuation coefficient Mass attenuation coefficients for water for photon energies from 1 keV to 300 keV 1 10 100 10- 3 10- 2 10- 1 100 101 102 103 104 Photon energy (keV) cm /g coherent incoherent photoelectric total Mass attenuation coefficient (cm 2 /g) The photoelectric interaction makes the dominant contribution to the total interaction cross section at the lowest energies. The steep decrease at the lower photon energies is characteristic for the photoelectric effect and ends when incoherent (Compton) scattering becomes dominant and remains so for the rest of the diagnostic energy range. The cross-over position for these two interactions depends on the atomic number For water is about 30 keV
  • 37. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 37 2.3. PHOTON ATTENUATION COEFFICIENTS 2.3.5. Contribution of individual interactions to the total mass attenuation coefficient 1 10 100 10- 2 100 102 104 Photon Energy (keV) Mass attenuation coefficient (cm 2 /g) iodine gadox lead adipose In the energy range up to 100 keV and for the high Z materials, the discontinuities arising from the differences in photoelectric absorption at K, L and M edges are evident Total mass interaction coefficients for materials relevant to diagnostic radiology (adipose tissue, iodine, gadolinium oxysulphide (gadox) and lead The differences in absorption that this creates are important for the design of filters used to shape X-ray spectra (particularly in mammography and for imaging using iodinated contrast agents)
  • 38. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 38 2.3. PHOTON ATTENUATION COEFFICIENTS 2.3.6. Coefficients for compounds and mixtures Mass attenuation coefficients and mass energy-transfer coefficients for compounds and intimate mixtures can be obtained by a weighted summation of the coefficients of the constituents: wi are the normalized weight fractions of the elements i (or mixture components i) present in the absorber The mass energy-absorption coefficient for an element accounts for the radiative losses of the secondary electrons i i i w ∑         =         ρ µ ρ µ i i i tr tr w ∑         =         ρ µ ρ µ i i i en en w ∑         =         ρ µ ρ µ
  • 39. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 39 2.4. INTERACTIONS OF ELECTRONS WITH MATTER Energy loss by electrons Ionizational or collisional losses Radiative losses or Bremsstrahlung Principal process: collisions with other electrons Energy losses and the changes in direction can be quite large The electron which leaves the collision with the most energy is assumed to be the original incident electron. This means the maximum energy exchange is half of the original energy Interaction with the electric field of nuclei and be decelerated so rapidly that some of its energy may be radiated away
  • 40. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 40 Energy lost by charged particles in passing through matter is generally described using a quantity called stopping power S 2.4. INTERACTIONS OF ELECTRONS WITH MATTER dT is the loss in kinetic energy of the particle as it travels a distance dx. ρ is the density of the material Stopping power Mass stopping power x T S d d = x T S d d 1 ρ ρ =
  • 41. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 41 2.4. INTERACTIONS OF ELECTRONS WITH MATTER 2.4.1. Ionizational (Collisional) Interactions and Ionizational Stopping Power This process involves collisions between electrons travelling through matter and electrons from atoms that are part of the material, leaving the atoms ionized It is rather difficult to measure the rate of energy lost by these interactions but is relatively easy to calculate it. Relativity and Quantum Mechanics must be used
  • 42. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 42 The problem was first solved by Bethe in the early part of the 20th century. The Ionizational Mass Stopping Power (Sion/ρ) (MeV⋅cm2 ⋅g-1) was derived by Bethe-Bloch and extended by Sternheimer: ( ) ( ) ( )         − − + + + − + + = δ β µ µ µ µ µ β µ π ρ 2 2 0 0 0 2 2 0 0 2 2 0 2 0 1 2 ln 2 8 / 2 2 ln 2 T T T I T T N r S e ion r0 is the “classical radius of the electron” Ne = NA(Z/Ar), NA is the Avogadro constant µ0 = m0c2 is the rest mass of the electron multiplied by the speed of light squared T is the kinetic energy β is the ratio of the speed of the electron to that of light The density correction term δ, was added later by Sternheimer. Its effect is to reduce energy losses, but only at high energies. At 100 MeV it can be as great as 20% I is a semi-empirical quantity called the “Mean Excitation Energy” which is a property of the material and increases as the atomic number of the material increases. Values of I for a large number of materials are given by NIST 2.4. INTERACTIONS OF ELECTRONS WITH MATTER 2.4.1. Ionizational (Collisional) Interactions and Ionizational Stopping Power
  • 43. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 43 ( ) ( ) ( )         − − + + + − + + = δ β µ µ µ µ µ β µ π ρ 2 2 0 0 0 2 2 0 0 2 2 0 2 0 1 2 ln 2 8 / 2 2 ln 2 T T T I T T N r S e ion Below 100 keV or so, the term 2π r0 2Ne µ0/β 2 is the most important The factor 1/β 2 = c2/v2 makes the stopping power nearly inversely proportional to the kinetic energy For energies above 100 keV β is essentially 1 and the term in front becomes nearly constant The terms inside the square bracket increase slowly with energy and the stopping power passes through a minimum in the neighborhood of 1 MeV 2.4. INTERACTIONS OF ELECTRONS WITH MATTER 2.4.1. Ionizational (Collisional) Interactions and Ionizational Stopping Power
  • 44. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 44 ( ) ( ) ( )         − − + + + − + + = δ β µ µ µ µ µ β µ π ρ 2 2 0 0 0 2 2 0 0 2 2 0 2 0 1 2 ln 2 8 / 2 2 ln 2 T T T I T T N r S e ion Dependence on atomic number is not strong The factor in front of the square brackets contains the number of electrons per unit mass, given by NA(Z/Ar), and remembering Z/Ar is 0.5 or slightly less, for all materials except hydrogen, the mass stopping power decreases only slightly as atomic number increases The mean excitation energy, I, increases as atomic number increases, which also serves to make Sion smaller for high atomic number materials 2.4. INTERACTIONS OF ELECTRONS WITH MATTER 2.4.1. Ionizational (Collisional) Interactions and Ionizational Stopping Power
  • 45. IAEA The function B = B(hν/T) is a slowly varying function of T and Z with an average for non-relativistic energies, T << m0c2, of 3 / 16 = B Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 45 2.4. INTERACTIONS OF ELECTRONS WITH MATTER 2.4.2. Radiative Interactions and Radiative Stopping Power When an electron passes close to a nucleus it will experience a substantial Coulomb force and will be decelerated, radiating energy in the form of electromagnetic radiation (Bremsstrahlung) The quantum mechanical solution is complicated and approximations must be made, and the most appropriate form for the result depends on the energy range The energy loss due to this process is quite strongly dependent on the atomic number, as can be seen by the Z2 term The approximate Radiative Mass Stopping Power (Srad/ρ )(MeV·cm2 ·g-1) for diagnostic energies is: = 0.580 barn/nucleus ( )B T Z A N S r A rad 0 2 0 µ σ ρ + = 2 0 2 0 137 1         = µ σ e
  • 46. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 46 2.4. INTERACTIONS OF ELECTRONS WITH MATTER 2.4.3. Total Stopping Power The total stopping power is the sum of the ionizational and radiative stopping powers: Ionizational, radiative and total stopping powers for water and tungsten for electron energies from 10 keV to 10 MeV 10 100 1000 10000 10- 3 10- 2 10- 1 100 101 102 Ionizational Radiative Total water Stopping power (MeV ⋅ cm 2 ⋅g -1 ) Energy (keV) 10 100 1000 10000 10- 2 10- 1 100 101 Ionizational Radiative Total tungsten Stopping power (MeV ⋅ cm 2 ⋅g -1 ) Energy (keV) rad ion tot S S S + =
  • 47. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 47 2.4. INTERACTIONS OF ELECTRONS WITH MATTER 2.4.4. Stopping power in Compounds and Mixtures The mass stopping power can be approximated for compounds or intimate mixtures by a weighed addition of the mass stopping power of the elemental constituents assuming independent contribution to stopping power: wi are the normalized weight fractions of the elements i present in the material. The influence of chemical binding is neglected here i i i w S S ∑         =         ρ ρ
  • 48. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 48 2.4. INTERACTIONS OF ELECTRONS WITH MATTER 2.4.5. Linear Energy Transfer The mass collision stopping power characterizes the energy loss of the electron due to all collisions. The secondary electrons resulting from hard collisions (δ-rays) carry part of the energy some distance away from the track and may escape the volume of interest In radiobiology, the use of the collision stopping power can result in an overestimation of dose. In such situations, the restricted stopping power may be used which relates to the energy lost in the absorber by secondary particles not exceeding an energy limit ∆ (typically 10 keV), thus limiting the volume of interest to the range of electrons with energy ∆ The restricted stopping power may be expressed as mass restricted stopping power (S/ρ)Res or, for a description of the energy passed to the medium per unit track length, it is common to use the linear energy transfer L∆ : Linear energy transfer L∆ (keV/µm): ∆ ∆         = x T L d d 1 10 ρ ρ
  • 49. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 49 2.5. DATA SOURCES Data for photon attenuation coefficients and stopping powers can be found in many textbooks but are conveniently obtained from web based data sources provided by: • NIST (Berger, Hubbell et al., 2005; Berger, Coursey, et al, 2005) or from the tabulations in: • ICRU (1992) The composition of body tissues and phantom materials are given in: • ICRU (1989) and • ICRP (2003)
  • 50. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 50 • BERGER, M.J., ESTAR, PSTAR AND ASTAR: Computer Programs for Calculating Stopping-Power and Ranges for Electrons, Protons and Helium Ions. NIST Report NISTIR-4999 (1992) • BERGER, M.J., COURSEY, J.S., ZUCKER, M.A. AND CHANG, J., ESTAR, PSTAR, and ASTAR: Computer Programs for Calculating Stopping-Power and Range Tables for Electrons, Protons and Helium Ions (version 1.2.3), NIST, Gaithersburg, MD (2005) Available: http://physics.nist.gov/Star [2008, February 7] • BERGER, M.J., HUBBELL, J.H., SELTZER, S.M., CHANG, J., COURSEY, J.S., SUKUMAR, R., and ZUCKER, D.S. (2005), XCOM: Photon Cross Section Database (version 1.3). Available: http://physics.nist.gov/xcom [2008, March 20]. NIST, Gaithersburg, MD BIBLIOGRAPHY
  • 51. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 51 BIBLIOGRAPHY • HUBBELL, J.H., Review of Photon Interaction Cross Section Data in the Medical and Biological Context, Phys. Med. Biol. 44 R1-22 (1999) • INTERNATIONAL COMMISSION ON RADIATION UNITS AND MEASUREMENTS, Stopping Powers for Electrons and Positrons, Rep. 37, ICRU, Bethesda, MD (1984) • INTERNATIONAL COMMISSION ON RADIATION UNITS AND MEASUREMENTS, Tissue Substitutes in Radiation Dosimetry and Measurement, Rep. 44, ICRU, Bethesda, MD (1989) • INTERNATIONAL COMMISSION ON RADIATION UNITS AND MEASUREMENTS, Photon, Electron, Proton and Neutron Interaction Data for Body Tissues, Rep. 46, ICRU, Bethesda, MD (1992)
  • 52. IAEA Diagnostic Radiology Physics: a Handbook for Teachers and Students – chapter 2, 52 BIBLIOGRAPHY • INTERNATIONAL COMMISSION ON RADIOLOGICAL PROTECTION, Basic Anatomical and Physiological Data for use in Radiological Protection: Reference Values ICRP Rep. 85, Pergamon Press, Oxford, (2003) • JOHNS, H.E. and CUNNINGHAM J.R. The Physics of Radiology (Fourth Edition), Charles C Thomas, Springfield, Illinois (1983) • NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (NIST), 100 Bureau Drive, Stop 1070, Gaithersburg, MD 20899- 1070. Available: http://www.nist.gov/index.html • SELTZER, S.M., BERGER, M.J., Evaluation of the Collision Stopping Power of Elements and Compounds for Electrons and Positrons, Int J Appl Radiat Isot 33, 1189-1218 (1982)