Dr. Elliott Bennett-Guerrero researches treatment methods for COVID-19 and safety of blood transfusions. An acute immune hemolytic reaction can occur if the donor's blood cells are incompatible with the recipient's, causing the immune system to attack the transfused blood cells. This reaction releases substances that can damage the kidneys and cause symptoms like fever, bloody urine, or fainting. In severe cases, it can lead to organ damage like acute kidney failure, though mild cases may pass without major harm. Doctors treat mild reactions with pain relievers and kidney-protecting medications. Proper screening of blood before transfusion can prevent such complications.