Slides from an informative webinar by Elemental Machines' Founder and CEO, Sridhar Iyengar, discussing how you can use Elemental Machines’ platform and wireless sensors to not only monitor your lab assets in real time from anywhere, at any time, but also instantly be notified the moment an asset malfunctions, the power fails, or a metric falls out of range. Watch the full webinar here: https://elementalmachines.com/maintain-peace-of-mind-24-7-with-lab-monitoring-and-alerting The Elemental Machines platform empowers Lab and Q&A managers to maintain peace of mind 24/7, establish a historical record without additional effort, fine tune your maintenance forecasts with data and AI and account and adjust for environmental variables in the lab.

1. MONITORING ANYTHING AND
EVERYTHING IN YOUR LAB
1
Sridhar Iyengar, PhD
CEO & Founder

2. Topics
Overview
Need for Monitoring
What’s Possible
Case Studies
Cool Hacks
2

3. Founded in 2014
500+ Customers
30,000+ Devices Deployed
80+ Employees
3

4. 4
Mission:
•To enable intelligent operations by connecting the physical
and digital infrastructure to optimize outcomes.
•Science and technology leaders trust Elemental Machines'
ecosystem of hardware and software to deliver actionable
insights that accelerate their pace of innovation.
•We enable data-driven discovery, development, and delivery
within organizations ranging from biopharma labs to
biobanks, analytical labs, and manufacturers in the life
sciences and beyond.

6. 6
LESS OF THIS

7. 7
MORE OF THIS

8. But 300M+ scientific assets
aren’t connected to anything…
(And they’re here to stay)
8

9. Current state of the “Connected” Lab — Silo’ed Workflows
9
MISSING DATA
Scientists miss key data from
experiments performed using
different systems. Often repeats
experiments w/o understanding
contextual problems
Instruments
300M Data Generators
SYSTEM INCOMPATIBILITY
Relevant data is lost between
systems due to missing
connectivity or translation errors.
Lab techs lose an average of
200 hrs every year to manual
data entry and translation from
system to system
LOST TIME
Protocols
E-Notebooks & LIMS
Analytics/Storage/SW
Multiple Data Consumers
Impact
Lost Productivity
UNIDENTIFIED SYSTEM FAILURE
System malfunction isn’t reported
to the lab administrator
LAB ADMINISTRATOR
Unexpected management of
experiment downtime due to
failed equipment - reactive, not
predictive.
REPEATED EXPERIMENT FAILURES
Scientists repeat failed
experiments due to lack of
contextual information.
LOST DATA
1/3 of research data cannot be
found after 2 years
Users
Who Did The Work?
Samples
What Reagents Were Used?

10. EM Cloud: Applications &
Analytics
10
Analytics / Storage / SW
E-Notebooks
Instruments,
Users, Samples
EM IOT
Integrates with customer's ELN/
LIMS for real-time procedure/
protocol guidance & instruction
Captures all relevant meta data
(user, sample, ambient conditions)
Automatically routes data to
correct repository (3rd party
ELN/ LIMS/ data lake)
Automatically gathers
instrument & usage data
Common Standards
Gets 300M+ existing
legacy instruments
online in 60 seconds
The EM Cloud — Seamless, Structured, Integrated

11. 11
What’s Possible

12. 12
Temperature Humidity
Liquid Nitrogen Levels
O2 Levels
RPMs
Light Levels
Pressure
CO2 Levels
Calibration History
Incubator Set Point
VOCs
Particulates
Vibration

13. Our Intelligent Platform Solution
Smart Contextual Alerts
Utilization Data
Ambient Data
Temperature Monitoring
Utilization
Software Integration
Equipment Integration

14. 14
68
70
72
74
76
12A 3A 6A 9A 12P 3P 6P 9P
70
71.5
73
74.5
76
2P 3P 4P 5P
Incubator #1
Incubator #2
Incubator #3
Incubator #4
0% 25% 50% 75% 100%
OPEN CLOSED
HOW OPERATIONAL DATA CAN BE
USED TO ANSWER QUESTIONS THAT
IMPROVE YOUR SCIENCE
-80
-50
-20
-82.5
-80
-77.5
-75

15. 15
68
70
72
74
76
12A 1A 2A 3A 4A 5A 6A 7A 8A 9A 10A 11A 12P 1P 2P 3P 4P 5P 6P 7P 8P 9P 10P 11P
70
71.5
73
74.5
76
2P 2:30P 3P 3:30P 4P 4:30P 5P
Was your Lab at the right temperature 24/7?

16. 16
Were your reagents stored correctly?
-80
-50
-20
-85
-82.5
-80
-77.5
-75

17. 17
Were your cells “disturbed” by other people?
Incubator #1
Incubator #2
Incubator #3
Incubator #4
0% 25% 50% 75% 100%
OPEN CLOSED

18. Automate Alerting and Monitoring with IoT
EM Sensors
Temperature
Humidity
Light
Pressure
Ambient
Water Spills
Third-Party Integrations
Air Flow Rate
Air Quality
Conductivity
Gas Flow Rate
Gas Manifold Alarm
Leak Alarm
Level % Full
Mass
O2
Particle Count
Resistivity
RPM
Salinity
TDS Factor
Tissue Processor Alert
Water Quality Alarm
C E RTA I N T Y
Measurements, issues,
and operability
S AV I N G S
Mitigate loss and
improve reproducibility
C A S E S T U D Y
$100,000 in media
saved by 1 AM alert of
cold room failure

19. 19
Automating compliance: Continuously watching out for “out of range” conditions
https://elementalmachines.com/blog/can-proper-humidity-fight-viruses-like-covid-19
Varian GCMS: 40% - 60% RH operating range
South Northeast
Midwest
West

20. User Training
Software Validation
Field Calibration
NIST Traceable Sensors
CFR Part 11 Reporting
Automating compliance: Records at your fingertips

21. Measure usage
via power cords
21

22. 22
ROI enabled by safe, non-invasive IoT device
Cellular backup
Battery powered Secure connectivity
Real-time & historic usage data
Standard “smart plugs”
• Invasive: In-line with instrument
• Potential damage risk to assets
• May introduce noise into power
line
Non-invasive
•Clamps to the OUTSIDE of power cord
•No-noise in power line
•No need to turn off equipment to install

23. Utilization is sometimes obvious…
23
Liquid Handler Cytometer
Centrifuge

24. … but often not…
24
Plate Reader
Plate Reader
Plate Reader

25. 25
Usage is powered by AI, delivering actionable insights

26. 26
Case Studies

27. 27
Lab prevented 3 years of
clinical trial samples from
being destroyed
They found one of their
freezers was “behaving oddly”
and caught a potential failure
before it occurred
Clinical Trial

28. 28
Lab saved $40,000 in 30 Days
Decommissioning & cancelling
service contracts for under-
utilized instruments
5X ROI
Big Pharma

29. 29
Company found the root
cause of strange behavior in
clinical data
Company’s scientists used EM’s
environmental data to deduce
that humidity interfered with
their device operation, saving ~
$1M and 6 months
Medical Device

30. 30
Lab reallocated $200,000
Eliminated lab space
expansion plans
50X ROI

31. 31
Cool Hacks

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36. Sign up for a FREE PILOT:
https://elementalmachines.com/get-your-free-pilot